Nature Reviews - Cardiology

JANUARY 29, 2024

Nature Reviews Cardiology, Published online: 30 January 2024; doi:10.1038/s41569-024-00990-7 In this Comment, we critically examine the association between the increasing consumption of ultra-processed foods and their negative effect on cardiovascular health. We explore the historical evolution of food processing, the Nova food classification and the epidemiological evidence, and highlight the need for urgent public health interventions.

Cardiovascular Disease 144

Cardiovascular Disease Public Health 144

American Heart News - Heart News

JANUARY 31, 2024

DALLAS, Feb. 1, 2024 – From news desks to iconic buildings, scores of people and landmarks across the U.S. will once again “go red” on National Wear Red Day, Feb. 2, to raise awareness that cardiovascular disease is the No. 1 killer of women and support.

Cardiovascular Disease 143

Cardiovascular Disease 143

Medical Xpress - Cardiology

JANUARY 25, 2024

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis, conducted by 23 experts from 11 countries, was led by The Johns Hopkins University in the United States, the Chinese University of Hong Kong in Hong Kong, and Lund University in Sweden.

Biomarkers 133

Biomarkers Cardiovascular Disease Diabetes Academic 133

Physiologically Speaking

JANUARY 10, 2024

Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Circadian rhythms in blood pressure and heart rate, among other functions, are crucial for cardiovascular health and preventing cardiovascular disease. Recent evidence indicates that nighttime light exposure impacts melatonin release, the autonomic nervous system, and cortisol — with potentially harmful effects on cardiovascular health.

Blood Pressure 131

Blood Pressure Physiology Cardiovascular Disease Obesity 131

Med Page Today

JANUARY 29, 2024

(MedPage Today) -- Getting clinicians to commit to the Choosing Wisely recommendations somewhat reduced low-value care for older adults in common scenarios, a cluster randomized trial found. After primary care clinicians committed in writing to.

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American Heart News - Stroke News

JANUARY 29, 2024

DALLAS, January 29, 2024 — A new scientific statement from the American Heart Association emphasizes the need to increase patients’ and physicians’ awareness of cerebral venous thrombosis (CVT) to improve the recognition of this condition and initiate.

Risk Factors 127

Risk Factors Thrombosis Stroke Strokes 127

Nature Reviews - Cardiology

JANUARY 1, 2024

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00962-3 Cardiovascular autonomic dysfunction (CVAD) is a malfunction of the autonomic control of circulatory homeostasis and is an important component of post-COVID-19 syndrome. In this Review, Fedorowski and colleagues define the major forms of CVAD (including postural orthostatic tachycardia syndrome), and discuss the aetiology, diagnosis and management of post-COVID-19 syndrome-associated CVAD.

COVID-19 145

COVID-19 Tachycardia 145

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension 132

Hypertension Circulation Blood Pressure Research 132

HCPLive

JANUARY 18, 2024

Both the FDA and EU regulators indicated visual acuity may serve as primary endpoint to evaluate MCO-010 in the treatment of low-vision retinitis pigmentosa patients.

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Cardiovascular Diabetology

JANUARY 19, 2024

Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and.

Cardiovascular Disease 126

Cardiovascular Disease Diabetes Research 126

Med Page Today

JANUARY 24, 2024

(MedPage Today) -- Ibuprofen again failed to improve short-term outcomes when used to close patent ductus arteriosus (PDA) in newborns, the placebo-controlled Baby-OSCAR trial showed. Administered parenterally a few days after infants were born.

Outcomes 125

Outcomes 125

Nature Reviews - Cardiology

JANUARY 3, 2024

Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments. Invasive and non-invasive imaging modalities used to assess plaque burden and composition are discussed.

Plaque 139

Plaque Cholesterol 139

ECG Weekly Workout

JANUARY 7, 2024

HPI: A young woman presents to the ED after a syncopal episode. She hit her chest after falling and has reproducible chest wall tenderness on exam. She is also noted to be febrile at triage, with reported malaise, vomiting, and unilateral back ache. The following ECG is obtained on arrival before the patient is hospitalized for pyelonephritis, chest pain, and syncope: Case ECG Before watching this week’s video.

Chest Pain 125

Chest Pain Hospital 125

Medical Xpress - Cardiology

JANUARY 24, 2024

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

Cancer 124

Cancer 124

HCPLive

JANUARY 12, 2024

A survey of more than 3000 US physicians is shedding light on the impact of taking vacation time and avoiding physician-related work on vacation can have on burnout and achieving professional fulfillment.

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Physiologically Speaking

JANUARY 12, 2024

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Physiology 125

Physiology BMI Exercise Diet 125

American Heart News - Heart News

JANUARY 11, 2024

DALLAS, Jan. 11, 2024 — Weather forecasters may call it ‘white fluffy stuff,’ however, snow can be a bigger danger than many people may realize. According to the American Heart Association, celebrating its Centennial birthday as the world’s leading.

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Nature Reviews - Cardiology

JANUARY 1, 2024

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00958-z In this Review, the authors discuss the latest insights on RNA-binding proteins and RNA biology and appraise them in the context of cardiovascular research, summarizing the progress in our understanding of the involvement of RNA-binding proteins in cardiac biology and disease.

Research 138

Research 138

Journal of Clinical Investigation - Cardiology

JANUARY 16, 2024

Heterozygous (HET) truncating variant mutations in the TTN gene (TTNtvs), encoding the giant titin protein, are the most common genetic cause of dilated cardiomyopathy (DCM). However, the molecular mechanisms by which TTNtv mutations induce DCM are controversial. Here, we studied 127 clinically identified DCM human cardiac samples with next-generation sequencing (NGS), high-resolution gel electrophoresis, Western blot analysis, and super-resolution microscopy in order to dissect the structural a

Cardiomyopathy 120

Cardiomyopathy 120

Cardiology Update

JANUARY 24, 2024

In 2020, a collaboration involving the Journal of the American College of Cardiology (JACC), the National Heart, Lung, and Blood Institute (NHLBI), and the Institute for Health Metrics and Evaluation (IHME) was formed to focus on CVD trends. The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology.

Cardiovascular Disease 119

Cardiovascular Disease Research Blood Pressure Public Health 119

HCPLive

JANUARY 29, 2024

This new research may require additional follow up studies on potential harms, as 63% of those in this study’s electronic cigarette arm continue to use the product at 6 months.

Research 122

Research 122

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Advanced heart failure (AdvHF) can only be treated definitively by heart transplantation (HTx), yet problems such right ventricle dysfunction (RVD), rejection, cardiac allograft vasculopathy (CAV), and primary graft dysfunction (PGD) are linked to a poor prognosis. As a result, numerous biomarkers have been investigated in an effort to identify and prevent certain diseases sooner.

Heart Transplant 119

Heart Transplant Biomarkers Transplant Heart Failure 119

Med Page Today

JANUARY 29, 2024

(MedPage Today) -- SAN ANTONIO -- The early experience of patients needing cardiac surgery after transcatheter aortic valve replacement (TAVR) has surgeons raising the alarm about the excess risks of these challenging procedures, based on data.

TAVR 119

TAVR Aortic valve Aortic 119

American Heart News - Heart News

JANUARY 24, 2024

DALLAS, Jan. 24, 2024 — In an effort to identify effective food is medicine approaches for incorporating healthy food into health care delivery, the American Heart Association, the world’s leading voluntary organization focused on heart and brain health.

Research 119

Research 119

Physiologically Speaking

JANUARY 5, 2024

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Plaque 120

Plaque Physiology Exercise Cholesterol 120

Cardiology Update

JANUARY 14, 2024

The perplexing landscape of angina with nonobstructive coronary arteries (ANOCA) encompasses diverse pathophysiological entities, including coronary microvascular disease (CMD), coronary artery spasm, and the enigmatic myocardial bridging (MB). Traditionally deemed benign, MBs, marked by the intramyocardial passage of an epicardial artery, are increasingly implicated in chronic angina and acute ischemic events.

Exercise 119

Exercise Ischemia Angina Physiology 119

HCPLive

JANUARY 12, 2024

A new study found the risk of Long COVID for short sleepers with pre-existing medical conditions was 3-fold higher than average-length sleepers without pre-existing conditions.

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Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

BACKGROUND Systemic administration of adeno-associated virus (AAV) can trigger life-threatening inflammatory responses, including thrombotic microangiopathy (TMA), acute kidney injury due to atypical hemolytic uremic syndrome–like complement activation, immune-mediated myocardial inflammation, and hepatic toxicity.METHODS We describe the kinetics of immune activation following systemic AAV serotype 9 (AAV9) administration in 38 individuals following 2 distinct prophylactic immunomodulation regim

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Med Page Today

JANUARY 24, 2024

(MedPage Today) -- A 4-month-old with congenital hyperinsulinism responded well to off-label treatment with a breast cancer drug, researchers reported. A newborn presented with severe congenital hyperinsulinism due to homozygous deletion of the.

Congenital 119

Congenital Cancer Research 119

American Heart News - Heart News

JANUARY 17, 2024

Research Highlights: Consistently high scores of perceived stress during adolescence through adulthood may contribute to worse cardiometabolic health including obesity in young adults. Researchers suggest the adoption of healthy coping strategies.

Obesity 119

Obesity Blood Pressure Diabetes Research 119

Science Daily - Heart Disease

JANUARY 31, 2024

Radon is the second leading cause of lung cancer. Now a new study has found exposure to this invisible, odorless gas is also linked to an increased risk of stroke. The study, which examined exposures in middle age to older female participants, found an increased risk of stroke among those exposed to high and even moderate concentrations of the gas compared to those exposed to the lowest concentrations.

Stroke 116

Stroke Strokes Cancer 116

Cardiovascular Diabetology

JANUARY 27, 2024

Underweight imposes significant burden on cardiovascular outcomes in patients with diabetes mellitus. However, less is known about the impact of serial change in body weight status measured as body mass index.

Cardiac Arrest 116

Cardiac Arrest Diabetes Outcomes Research 116

HCPLive

JANUARY 3, 2024

Mindfulness-Oriented Recovery Enhancement plus methadone treatment is a promising treatment option for patients with opioid use disorder, having been significantly associated with less return to drug use and methadone treatment dropout, a new study found.

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Cardiology Update

JANUARY 28, 2024

The optimal management of concomitant chronic obstructive coronary artery disease (CAD) in transcatheter aortic valve replacement (TAVR) recipients remains a debated topic. While some advocate for pre-TAVR percutaneous coronary intervention, others adopt an expectant approach. In a recent study published in the European Heart Journal, researchers investigated the influence of varying degrees and extent of untreated chronic obstructive CAD on TAVR outcomes and longer-term results.

TAVR 115

TAVR Aortic valve Outcomes Coronary Artery Disease 115

Med Page Today

JANUARY 9, 2024

(MedPage Today) -- Men treated with androgen deprivation therapy (ADT) for prostate cancer had a significantly higher risk of dementia and other neurocognitive disorders, according to a meta-analysis of more than 2.5 million patients. The magnitude.

Cancer 119

Cancer Dementia 119

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Objective This study aims to assess the ability of state-of-the-art machine learning algorithms to detect valvular heart disease (VHD) from digital heart sound recordings in a general population that includes asymptomatic cases and intermediate stages of disease progression. Methods We trained a recurrent neural network to predict murmurs from heart sound audio using annotated recordings collected with digital stethoscopes from four auscultation positions in 2,124 participants from the Tromsø7 s

Heart Disease 116

Heart Disease Stenosis Aortic Bicuspid/Mitral 116

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

Virophagy, the selective autophagosomal engulfment and lysosomal degradation of viral components, is crucial for neuronal cell survival and antiviral immunity. However, the mechanisms leading to viral antigen recognition and capture by autophagic machinery remain poorly understood. Here, we identified cyclin-dependent kinase–like 5 (CDKL5), known to function in neurodevelopment, as an essential regulator of virophagy.

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