Nature Reviews - Cardiology

JANUARY 29, 2024

Nature Reviews Cardiology, Published online: 30 January 2024; doi:10.1038/s41569-024-00990-7 In this Comment, we critically examine the association between the increasing consumption of ultra-processed foods and their negative effect on cardiovascular health. We explore the historical evolution of food processing, the Nova food classification and the epidemiological evidence, and highlight the need for urgent public health interventions.

Cardiovascular Disease 144

Cardiovascular Disease Public Health 144

American Heart News - Heart News

JANUARY 31, 2024

DALLAS, Feb. 1, 2024 – From news desks to iconic buildings, scores of people and landmarks across the U.S. will once again “go red” on National Wear Red Day, Feb. 2, to raise awareness that cardiovascular disease is the No. 1 killer of women and support.

Cardiovascular Disease 144

Cardiovascular Disease 144

Med Page Today

JANUARY 24, 2024

(MedPage Today) -- Ibuprofen again failed to improve short-term outcomes when used to close patent ductus arteriosus (PDA) in newborns, the placebo-controlled Baby-OSCAR trial showed. Administered parenterally a few days after infants were born.

Outcomes 139

Outcomes 139

Medical Xpress - Cardiology

JANUARY 25, 2024

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis, conducted by 23 experts from 11 countries, was led by The Johns Hopkins University in the United States, the Chinese University of Hong Kong in Hong Kong, and Lund University in Sweden.

Cardiovascular Disease 133

Cardiovascular Disease Biomarkers Diabetes Academic 133

American Heart News - Stroke News

JANUARY 29, 2024

DALLAS, January 29, 2024 — A new scientific statement from the American Heart Association emphasizes the need to increase patients’ and physicians’ awareness of cerebral venous thrombosis (CVT) to improve the recognition of this condition and initiate.

Risk Factors 133

Risk Factors Thrombosis Stroke Strokes 133

Physiologically Speaking

JANUARY 10, 2024

Our body’s physiological processes oscillate on a 24-hour cycle known as the circadian rhythm. Circadian rhythms in blood pressure and heart rate, among other functions, are crucial for cardiovascular health and preventing cardiovascular disease. Recent evidence indicates that nighttime light exposure impacts melatonin release, the autonomic nervous system, and cortisol — with potentially harmful effects on cardiovascular health.

Blood Pressure 131

Blood Pressure Physiology Cardiovascular Disease Obesity 131

Nature Reviews - Cardiology

JANUARY 1, 2024

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00962-3 Cardiovascular autonomic dysfunction (CVAD) is a malfunction of the autonomic control of circulatory homeostasis and is an important component of post-COVID-19 syndrome. In this Review, Fedorowski and colleagues define the major forms of CVAD (including postural orthostatic tachycardia syndrome), and discuss the aetiology, diagnosis and management of post-COVID-19 syndrome-associated CVAD.

COVID-19 145

COVID-19 Tachycardia 145

Med Page Today

JANUARY 29, 2024

(MedPage Today) -- SAN ANTONIO -- The early experience of patients needing cardiac surgery after transcatheter aortic valve replacement (TAVR) has surgeons raising the alarm about the excess risks of these challenging procedures, based on data.

TAVR 137

TAVR Aortic valve Aortic 137

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension 132

Hypertension Circulation Blood Pressure Research 132

HCPLive

JANUARY 18, 2024

Both the FDA and EU regulators indicated visual acuity may serve as primary endpoint to evaluate MCO-010 in the treatment of low-vision retinitis pigmentosa patients.

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Cardiovascular Diabetology

JANUARY 19, 2024

Legume consumption has been linked to a reduced risk of type 2 diabetes (T2D) and cardiovascular disease (CVD), while the potential association between plasma metabolites associated with legume consumption and.

Cardiovascular Disease 126

Cardiovascular Disease Diabetes Research 126

Nature Reviews - Cardiology

JANUARY 3, 2024

Nature Reviews Cardiology, Published online: 04 January 2024; doi:10.1038/s41569-023-00979-8 In this Review, Sarraju and Nissen summarize the clinical trial evidence for coronary atherosclerotic plaque stabilization and regression with plasma LDL-cholesterol-lowering therapy and other treatments. Invasive and non-invasive imaging modalities used to assess plaque burden and composition are discussed.

Plaque 139

Plaque Cholesterol 139

American Heart News - Heart News

JANUARY 24, 2024

DALLAS, Jan. 24, 2024 — In an effort to identify effective food is medicine approaches for incorporating healthy food into health care delivery, the American Heart Association, the world’s leading voluntary organization focused on heart and brain health.

Research 127

Research 127

Med Page Today

JANUARY 29, 2024

(MedPage Today) -- Getting clinicians to commit to the Choosing Wisely recommendations somewhat reduced low-value care for older adults in common scenarios, a cluster randomized trial found. After primary care clinicians committed in writing to.

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Medical Xpress - Cardiology

JANUARY 24, 2024

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

Cancer 124

Cancer 124

ECG Weekly Workout

JANUARY 7, 2024

HPI: A young woman presents to the ED after a syncopal episode. She hit her chest after falling and has reproducible chest wall tenderness on exam. She is also noted to be febrile at triage, with reported malaise, vomiting, and unilateral back ache. The following ECG is obtained on arrival before the patient is hospitalized for pyelonephritis, chest pain, and syncope: Case ECG Before watching this week’s video.

Chest Pain 125

Chest Pain Hospital 125

HCPLive

JANUARY 12, 2024

A survey of more than 3000 US physicians is shedding light on the impact of taking vacation time and avoiding physician-related work on vacation can have on burnout and achieving professional fulfillment.

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Nature Reviews - Cardiology

JANUARY 1, 2024

Nature Reviews Cardiology, Published online: 02 January 2024; doi:10.1038/s41569-023-00958-z In this Review, the authors discuss the latest insights on RNA-binding proteins and RNA biology and appraise them in the context of cardiovascular research, summarizing the progress in our understanding of the involvement of RNA-binding proteins in cardiac biology and disease.

Research 138

Research 138

American Heart News - Heart News

JANUARY 11, 2024

DALLAS, Jan. 11, 2024 — Weather forecasters may call it ‘white fluffy stuff,’ however, snow can be a bigger danger than many people may realize. According to the American Heart Association, celebrating its Centennial birthday as the world’s leading.

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Med Page Today

JANUARY 1, 2024

(MedPage Today) -- In January, we reported on Damar Hamlin's collapse during a televised football game. In this report, we follow up on the resulting public interest on sudden cardiac arrest that made Hamlin the most searched person of 2023. During.

Cardiac Arrest 134

Cardiac Arrest 134

Physiologically Speaking

JANUARY 12, 2024

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Physiology 124

Physiology BMI Exercise Diet 124

Journal of Clinical Investigation - Cardiology

JANUARY 16, 2024

Heterozygous (HET) truncating variant mutations in the TTN gene (TTNtvs), encoding the giant titin protein, are the most common genetic cause of dilated cardiomyopathy (DCM). However, the molecular mechanisms by which TTNtv mutations induce DCM are controversial. Here, we studied 127 clinically identified DCM human cardiac samples with next-generation sequencing (NGS), high-resolution gel electrophoresis, Western blot analysis, and super-resolution microscopy in order to dissect the structural a

Cardiomyopathy 120

Cardiomyopathy 120

HCPLive

JANUARY 29, 2024

This new research may require additional follow up studies on potential harms, as 63% of those in this study’s electronic cigarette arm continue to use the product at 6 months.

Research 122

Research 122

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Advanced heart failure (AdvHF) can only be treated definitively by heart transplantation (HTx), yet problems such right ventricle dysfunction (RVD), rejection, cardiac allograft vasculopathy (CAV), and primary graft dysfunction (PGD) are linked to a poor prognosis. As a result, numerous biomarkers have been investigated in an effort to identify and prevent certain diseases sooner.

Heart Transplant 119

Heart Transplant Biomarkers Transplant Heart Failure 119

American Heart News - Heart News

JANUARY 17, 2024

Research Highlights: Consistently high scores of perceived stress during adolescence through adulthood may contribute to worse cardiometabolic health including obesity in young adults. Researchers suggest the adoption of healthy coping strategies.

Obesity 127

Obesity Blood Pressure Diabetes Research 127

Med Page Today

JANUARY 29, 2024

(MedPage Today) -- One class of glucose-lowering agent may help lower the risk of kidney stones in adults with type 2 diabetes, a cohort study suggested. Adults who newly started on an SGLT2 inhibitor had a 31% lower risk of nephrolithiasis compared.

Diabetes 129

Diabetes 129

Physiologically Speaking

JANUARY 5, 2024

Greetings! Welcome to the Physiology Friday newsletter. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.” Details can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Plaque 119

Plaque Physiology Exercise Cholesterol 119

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

BACKGROUND Systemic administration of adeno-associated virus (AAV) can trigger life-threatening inflammatory responses, including thrombotic microangiopathy (TMA), acute kidney injury due to atypical hemolytic uremic syndrome–like complement activation, immune-mediated myocardial inflammation, and hepatic toxicity.METHODS We describe the kinetics of immune activation following systemic AAV serotype 9 (AAV9) administration in 38 individuals following 2 distinct prophylactic immunomodulation regim

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HCPLive

JANUARY 12, 2024

A new study found the risk of Long COVID for short sleepers with pre-existing medical conditions was 3-fold higher than average-length sleepers without pre-existing conditions.

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Cardiovascular Diabetology

JANUARY 27, 2024

Underweight imposes significant burden on cardiovascular outcomes in patients with diabetes mellitus. However, less is known about the impact of serial change in body weight status measured as body mass index.

Cardiac Arrest 116

Cardiac Arrest Diabetes Outcomes Research 116

American Heart News - Heart News

JANUARY 9, 2024

DALLAS, Jan. 9, 2024 — A physician-scientist from Massachusetts researching whether chemicals naturally occurring in foods could help treat heart disease, a genetics expert from Pennsylvania exploring the molecular mechanisms of lipid metabolism and.

Heart Disease 121

Heart Disease Research 121

Med Page Today

JANUARY 18, 2024

(MedPage Today) -- The new nomenclature for classifying steatotic liver disease (SLD) can help clinicians determine distinct prognoses, with the integration of alcohol intake as an aid in risk stratification, according to an analysis of a prospective.

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Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Objective This study aims to assess the ability of state-of-the-art machine learning algorithms to detect valvular heart disease (VHD) from digital heart sound recordings in a general population that includes asymptomatic cases and intermediate stages of disease progression. Methods We trained a recurrent neural network to predict murmurs from heart sound audio using annotated recordings collected with digital stethoscopes from four auscultation positions in 2,124 participants from the Tromsø7 s

Heart Disease 116

Heart Disease Stenosis Aortic Bicuspid/Mitral 116

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

Virophagy, the selective autophagosomal engulfment and lysosomal degradation of viral components, is crucial for neuronal cell survival and antiviral immunity. However, the mechanisms leading to viral antigen recognition and capture by autophagic machinery remain poorly understood. Here, we identified cyclin-dependent kinase–like 5 (CDKL5), known to function in neurodevelopment, as an essential regulator of virophagy.

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HCPLive

JANUARY 3, 2024

Mindfulness-Oriented Recovery Enhancement plus methadone treatment is a promising treatment option for patients with opioid use disorder, having been significantly associated with less return to drug use and methadone treatment dropout, a new study found.

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Medical Xpress - Cardiology

JANUARY 11, 2024

Data from the St. Jude lifetime cohort study (St. Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Early detection through screening using these two biomarkers may lead to earlier treatment to prevent and protect against further heart damage.

Biomarkers 116

Biomarkers Cancer Cardiac Function Cardiomyopathy 116

American Heart News - Heart News

JANUARY 23, 2024

Research Highlights: Positive, warm relationships between caregiver and child were associated with higher odds of attaining ideal heart health at multiple points across a 20-year span of adulthood. Meanwhile, experiencing childhood adversity such as.

Research 112

Research 112