Outcomes - Cardiovascular Update

Ezetimibe Plus Statins Equals Better Outcomes

CardiacWire

MARCH 26, 2025

Digging through decades of data from PubMed, Embase, and ClinicalTrials.gov, researchers pooled all relevant articles published through June 2024 (108k patients) and found that a combination lipid-lowering therapy (LLT) of statins plus ezetimibe led to significantly better CV outcomes compared to statin monotherapy.

Outcomes

Outcomes Cholesterol Article Research

Esperion Presents New Data from CLEAR Outcomes Trial Highlighting Value of NEXLETOL

DAIC

DECEMBER 3, 2024

18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with Peripheral Artery Disease (PAD) who were unable or unwilling to take statin medications. tim.hodson Tue, 12/03/2024 - 16:52 Nov. These data were presented at the 2024 American Heart Association Scientific Sessions, in Chicago, IL.

Outcomes

Outcomes Peripheral Arterial Disease Ischemia Research

The relationship between blood glucose and clinical outcomes after extracorporeal circulation: a retrospective cohort study

Frontiers in Cardiovascular Medicine

MARCH 30, 2025

BackgroundPostoperative blood glucose levels significantly impact outcomes in cardiac surgery patients undergoing extracorporeal circulation (ECC) auxiliary to open heart surgery. While hypoglycemia and hyperglycemia are known risk factors for adverse outcomes, the optimal glycemic range for patients undergoing ECC remains unclear.

Open-Heart Surgery

Open-Heart Surgery Circulation ICU Outcomes

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

IntroductionThere is growing evidence that patients with SARS-CoV-2 (The severe acute respiratory syndrome coronavirus 2) may have a variety of cardiovascular complications in the post-acute phase of COVID-19, but these manifestations have not yet been comprehensively characterized.MethodsWe performed a systematic review and meta-analysis of primary (..)

COVID-19

COVID-19 Cardiogenic Shock Cardiomyopathy Outcomes

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. From Research to Real-World Care 🌎 Understand how AI-driven advancements are shaping personalized treatments and patient outcomes. But its impact goes far beyond research.

Patient Care

Altshock-2: Early IABP Implantation Does Not Improve Outcomes For HF-CS

American College of Cardiology

MARCH 30, 2025

Implantation of an intra-aortic balloon pump (IABP) did not improve 60-day survival or bridge to heart replacement (HRT) therapies in patients with heart failure-cardiogenic shock (HF-CS) compared to standard care, according to a study presented during a Featured Clinical Research session at ACC.25 25 in Chicago and simultaneously published in JACC.

Cardiogenic Shock

Cardiogenic Shock Heart Failure Outcomes Aortic

New Tool Helps Predict Stroke Outcome with Higher Accuracy

DAIC

JANUARY 30, 2025

By integrating a real-time frailty risk score into the electronic medical record (EMR), presenting stroke severity and other variables, we can proactively identify who will benefit from immediate surgery and who may need pre-habilitating before surgery to achieve better outcomes.

Stroke

Stroke Strokes Outcomes Quality of Life

Prevalence and predictors of poor heart failure treatment outcomes in Ethiopia: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

DECEMBER 23, 2024

Various factors can exacerbate disease progression in patients with HF and negatively impact treatment outcomes. Publication bias was assessed using Begg's test, Egger's weighted regression, and funnel plots.ResultsThe pooled prevalence of poor HF treatment outcomes was found to be 16.67% [95% confidence interval (CI): 10.6722.67].

Heart Failure

Heart Failure Outcomes Education

Sexual and Gender Minorities More Likely to Have Adverse Brain Outcomes

Med Page Today

SEPTEMBER 25, 2024

(MedPage Today) -- People who identified as a sexual or gender minority (LGBTQ+) had a higher likelihood of adverse brain health outcomes, cross-sectional data showed. Among nearly 400,000 participants in the All of Us research program, sexual.

Outcomes

Outcomes Research

Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using double-disc occluders

Frontiers in Cardiovascular Medicine

MARCH 28, 2025

This study aimed to evaluate the early and mid-term outcomes of transcatheter closure using a double-disc occluder device in a single-center Vietnamese cohort.MethodA prospective descriptive study was conducted at Hanoi Heart Hospital, Vietnam. Data were analyzed using SPSS 20.0.ResultsThe

VSD

VSD Outcomes Congenital Heart Disease Aortic valve

Artificial blood vessels could improve heart bypass outcomes

Science Daily - Heart Disease

JULY 25, 2024

Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

Outcomes

Outcomes Technology Cardiovascular Disease

Surgeon Preference Impacts Survival Outcomes Analyses for CABG Patients

DAIC

JANUARY 24, 2025

the data and outcomes from the STS Database specialty registries provide true national benchmarks for clinical outcomes of cardiothoracic surgery. Dr. Schaffers team was somewhat surprised by the results of our surgeon-preference analysis. If you enjoy this content, please share it with a colleague

Outcomes

Outcomes Coronary Artery Bypass Graft Cardiothoracic Medicare

TAVR System Shows Durable Clinical Outcomes, Strong Valve Performance in Low-Risk Aortic Stenosis Patients

DAIC

MARCH 31, 2025

tim.hodson Mon, 03/31/2025 - 15:39 March 30, 2025 Medtronic has announced late-breaking data on five-year outcomes from the Evolut Low Risk Trial. Two-Year Outcomes of the Five-Year SMART Trial, presented at CRT 2025. Additional findings at five years include: Numerically lower rate of cardiovascular mortality (7.2% Evolut TAVR vs. 9.3%

TAVR

TAVR Stenosis Aortic Outcomes

Peripandemic outcomes of infants treated for sentinel congenital heart diseases in England and Wales

Open Heart

FEBRUARY 17, 2025

We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups. Outcomes did not vary by pandemic birth era according to social characteristics.

Congenital Heart Disease

Congenital Heart Disease Congenital Heart Disease Outcomes

Serious Outcomes of Steatotic Liver Disease Hit Men and Women Differently

Med Page Today

DECEMBER 4, 2024

(MedPage Today) -- Serious outcomes associated with metabolic dysfunction-associated steatotic liver disease (MASLD) -- including liver cancer, cirrhosis, heart disease, and more -- affect men and women differently, a large cohort study of.

Outcomes

Outcomes Cancer Heart Disease

Trends in the Clinical Characteristics and Outcome of Infective Endocarditis: A Nationwide Study From 2016 to 2021

Journal of the American Heart Association

DECEMBER 31, 2024

BackgroundInfective endocarditis (IE) is still a fatal disease, and given its rarity, ongoing updates to patient characteristics and outcomes of IE are essential for providing precision diagnoses and effective treatments.

Outcomes

Outcomes Heart Failure Risk Factors

Diagnostic pathways, cardiac manifestations and outcomes in light chain amyloidosis: analysis of a US claims database

Open Heart

APRIL 4, 2025

We qualitatively and quantitatively characterised the diagnostic pathway and the impact of delayed diagnosis on health outcomes among patients with AL amyloidosis. Background Patients with light chain (AL) amyloidosis, a rare life-threatening disease, often go through a lengthy diagnostic journey.

Inpatient

Inpatient Outcomes

Sotalol Dosing and Outcomes Among Patients Undergoing Intravenous Loading for Atrial Arrhythmias—A PEAKS Registry Substudy

Journal of Cardiovascular Electrophysiology

APRIL 9, 2025

To date, use and outcomes by dose are not well-described. Methods In the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry, we analyzed outcomes among patients undergoing elective IV sotalol load for atrial arrhythmias (AT/AF).

Arrhythmia

Arrhythmia Outcomes Atrial Fibrillation Hospital

National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era

Journal of Cardiothoracic Surgery

NOVEMBER 12, 2024

We examined the nationwide trends and outcomes of cardiovas. With an aging population and higher prevalence of dementia, there is a paucity of data regarding dementia patients undergoing cardiovascular surgery.

Dementia

Dementia Cardiovascular Surgery Outcomes Research

Beyond Calcium: A Holistic Approach to Optimizing Outcomes for Patients with Hypoparathyroidism

HCPLive

MARCH 13, 2025

Chronic hypoparathyroidism requires holistic management addressing more than just calcium normalization to achieve optimal patient outcomes.

Outcomes

Stroke procedural numbers are an unreliable predictor of patient outcomes, finds study

Medical Xpress - Cardiology

JANUARY 23, 2025

According to new research from the University of Missouri School of Medicine, the number of mechanical thrombectomies performed at hospitals is not an accurate indicator of patient outcomes.

Outcomes

Outcomes Stroke Strokes Hospital

Temporal left ventricular ejection fraction variations and outcomes in wide population of cardiovascular patients with and without heart failure

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

IntroductionHeart failure (HF) with improved ejection fraction (HFimpEF) was shown to be related with improved outcome but increase of left ventricular ejection fraction (LVEF) in patients without HF is of less known clinical significance.

Heart Failure

Heart Failure Outcomes Academic Research

Predictors for long-term outcome of pulmonary valve perforation and balloon valvuloplasty in neonates with critical pulmonary valve stenosis or pulmonary valve atresia with intact ventricular septum

Frontiers in Cardiovascular Medicine

MARCH 12, 2025

ConclusionPulmonary valve perforation and PBV achieved favorable long-term outcomes in neonates with PA/IVS and CPS. IntroductionPercutaneous balloon valvuloplasty is the treatment of choice for critical pulmonary valve stenosis (CPS) and pulmonary valve atresia with intact ventricular septum (PA/IVS) if the ventricle has a suitable size.

Pulmonary

Pulmonary Stenosis Outcomes Hospital

Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta‐analysis

European Journal of Heart Failure

MARCH 10, 2025

Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis. To address these inconsistencies, the present meta-analysis aimed to evaluate the association of CH with the incidence and clinical outcomes of HF. Clonal haematopoiesis and heart failure: a meta-analysis.

Heart Failure

Heart Failure Outcomes Coronary Artery Disease Risk Factors

The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experience”

Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

The primary outcome was survival at the follow-up evaluation. More homogeneous and adequately powered cohorts are needed to better understand the impact of VAD support on posttransplant outcomes. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.

Heart Transplant

Heart Transplant Transplant Pediatrics Heart Failure

Sedentary Behavior and Light-Intensity Physical Activity During Pregnancy and Cardiovascular Health: A Science Advisory From the American Heart Association

Circulation

APRIL 10, 2025

The purpose of this American Heart Association science advisory is to describe the existing evidence on device-measured sedentary behavior and light-intensity physical activity in relation to cardiovascular health during pregnancy and to make specific calls to action for future research to improve health outcomes and to promote health equity.

Blood Pressure

Blood Pressure Cardiovascular Disease Outcomes Hypertension

Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis

Journal of Cardiothoracic Surgery

FEBRUARY 4, 2025

Background The present study aimed to critically revise the published literature on clinical outcomes and cost-effectiveness of Inspiris Resilia valve. Methods This work was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines.

Aortic valve

Aortic valve Aortic Outcomes Article

Impact of HFpEF on Ablation Outcomes; PVI Only Ablation in HFrEF?

American College of Cardiology

APRIL 18, 2025

Patients who undergo catheter ablation for atrial fibrillation (AFib) who also have heart failure with preserved ejection fraction (HFpEF) experienced a greater benefit from ablation in terms of clinical outcome, AFib recurrence and functional status, according to findings from the CABANA trial.

Preserved Ejection Fraction

Preserved Ejection Fraction Ablation AFIB Atrial Fibrillation

Patient-Reported Outcomes as End Points in Heart Failure Trials

Circulation

APRIL 13, 2025

Although traditional therapeutic strategies have focused on reducing the risk for hospitalization and mortality, the importance of patient-reported outcomes (PROs) in patients with heart failure is increasingly being recognized. Heart failure is a growing health-care concern affecting tens of millions of individuals globally.

Heart Failure

Heart Failure Outcomes Article Cardiomyopathy

SUMMIT: No Impact From Baseline eGFR on HF Outcomes With Tirzepatide

American College of Cardiology

MARCH 31, 2025

25 in Chicago and simultaneously published in JACC.

Preserved Ejection Fraction

Preserved Ejection Fraction Kidney Disease Obesity Heart Failure

Better Cognitive Outcomes Tied to Vigorous Exercise in Hypertensive Adults

Med Page Today

JUNE 6, 2024

(MedPage Today) -- Vigorous exercise appeared to preserve cognitive function in older adults with hypertension, a post hoc analysis of SPRINT MIND trial data showed. At least one vigorous physical activity session per week reduced the risk of.

Exercise

Exercise Hypertension Outcomes

New approach to defibrillation may improve cardiac arrest outcomes

Science Daily - Heart Disease

SEPTEMBER 23, 2024

A new observational study suggests the position in which responders initially place the two defibrillator pads on the body may make a significant difference in returning spontaneous blood circulation after shock from a defibrillator.

Defibrillator

Defibrillator Cardiac Arrest Outcomes Circulation

Hearing Loss and Heart Failure; Improved TAVR Outcomes

Med Page Today

APRIL 19, 2025

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

TAVR

TAVR Heart Failure Outcomes

Blood pressure trial intervention shows mixed outcomes in chronic kidney disease patients

Medical Xpress - Cardiology

JANUARY 10, 2025

Stanford University School of Medicineled researchers have found that intensive blood pressure (BP) control produces cardiovascular benefits and increases the risk of adverse events in people with chronic kidney disease (CKD).

Blood Pressure

Blood Pressure Kidney Disease Outcomes Research

Chest pain and computer ‘normal’ ECG. Wait for troponin? And what is the reference standard for ECG diagnosis? Cardiologist or outcome?

Dr. Smith's ECG Blog

MARCH 10, 2025

They concluded, "Our findings increase confidence in the normal automated GE Marquette 12 SL ECG software interpretation to predict a benign outcome. Smith comment: this is a very stupid outcome measure) What if we use that methodology for the ECG above? What is the gold standard for ECG interpretation: patient outcome!!!

Chest Pain

Chest Pain Outcomes STEMI Electrocardiogram

Renal Outcomes Seem to Differ By Gender After Living Kidney Donation

Med Page Today

APRIL 12, 2025

(MedPage Today) -- BOSTON -- After living kidney donation, projection of renal function may vary by gender, a retrospective cohort study of 174,311 living kidney donors suggested. Over a median 6.7 months, the incidence rate of worsening post.

Outcomes

Poor Hepatitis D Screening in HBV Patients Impacts Survival Outcomes

HCPLive

OCTOBER 15, 2024

A new study highlights suboptimal HDV screening rates in HBV-infected individuals, suggesting that treating HBV may improve survival for those with HDV coinfection.

Outcomes

Combined Tacrolimus, Belatacept Regimen Improves Post-Kidney Transplant Outcomes

HCPLive

JANUARY 30, 2025

Findings suggest the benefits of combined belatacept and tacrolimus immunosuppression after kidney transplantation for patient and all-cause graft survival.

Transplant

Transplant Outcomes

Optimizing Psychological Health Across the Perinatal Period: An Update on Maternal Cardiovascular Health: A Scientific Statement From the American Heart Association

Journal of the American Heart Association

FEBRUARY 25, 2025

Perinatal psychological health conditions (eg, perinatal depression, anxiety) are some of the leading causes of maternal mortality in the United States and are associated with adverse pregnancy outcomes, longterm cardiovascular outcomes, and intergenerational effects on offspring neurodevelopment.

Pharmacology

Pharmacology Outcomes

Interventions for adult congenital heart disease

Nature Reviews - Cardiology

JANUARY 19, 2025

In this Review, Rods-Cabau and colleagues provide a comprehensive overview of the available transcatheter interventions for these patients, focusing on their current indications and associated outcomes.

Congenital Heart Disease

Congenital Heart Disease Congenital Heart Disease Outcomes

Patients Who Received Ross Procedure Demonstrate Excellent Survival Rates after 20 Years

Society of Thoracic Surgeons - Adult Cardiac

JANUARY 26, 2025

We wanted to examine our outcomes, and we were pleasantly surprised to find that the freedom from re-intervention was 91% at 10 years and 87% at 20 years. Congenital All Members Clinical Decision-Making Patient Outcomes Quality Improvement The main drawback of the Ross operation is failure of the autograft over time, Dr. Shetty said.

Aortic valve

Aortic valve Cardiothoracic Congenital Aortic

Insulin Beats Oral Alternatives for Gestational Diabetes Outcome

Med Page Today

JANUARY 6, 2025

(MedPage Today) -- Oral glucose-lowering medications weren't up to snuff with insulin for gestational diabetes, a randomized clinical trial found. Among 820 individuals, 23.9% of infants born to mothers treated with a sequential regimen of metformin.

Diabetes

Diabetes Outcomes

Surgical and transcatheter aortic valve interventions for aortic stenosis in England: sociodemographic variations in treatment trends and outcome over 20 years

Heart BMJ

FEBRUARY 26, 2025

Background Health inequalities in cardiovascular care have been identified in the UK. The sociodemographic characteristics of patients undergoing intervention for aortic stenosis (AS) in England, and the impact of COVID-19, is unknown.

Aortic valve

Aortic valve Aortic COVID-19 Stenosis

Aquatic Exercise Improves Physical, Psychosocial Outcomes in People With ME/CFS

HCPLive

APRIL 17, 2025

People with ME/CFS also have a high comorbidity rate of fibromyalgia, which has also been seen to improve with aquatic exercise.

Exercise

Exercise Outcomes

Ezetimibe Plus Statins Equals Better Outcomes

Esperion Presents New Data from CLEAR Outcomes Trial Highlighting Value of NEXLETOL

The relationship between blood glucose and clinical outcomes after extracorporeal circulation: a retrospective cohort study

Webinars

Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis

Bridging Innovation & Patient Care: The Growing Role of AI

Altshock-2: Early IABP Implantation Does Not Improve Outcomes For HF-CS

New Tool Helps Predict Stroke Outcome with Higher Accuracy

Prevalence and predictors of poor heart failure treatment outcomes in Ethiopia: a systematic review and meta-analysis

Sexual and Gender Minorities More Likely to Have Adverse Brain Outcomes

Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using double-disc occluders

Artificial blood vessels could improve heart bypass outcomes

Surgeon Preference Impacts Survival Outcomes Analyses for CABG Patients

TAVR System Shows Durable Clinical Outcomes, Strong Valve Performance in Low-Risk Aortic Stenosis Patients

Peripandemic outcomes of infants treated for sentinel congenital heart diseases in England and Wales

Serious Outcomes of Steatotic Liver Disease Hit Men and Women Differently

Trends in the Clinical Characteristics and Outcome of Infective Endocarditis: A Nationwide Study From 2016 to 2021

Diagnostic pathways, cardiac manifestations and outcomes in light chain amyloidosis: analysis of a US claims database

Sotalol Dosing and Outcomes Among Patients Undergoing Intravenous Loading for Atrial Arrhythmias—A PEAKS Registry Substudy

National outcomes for dementia patients undergoing cardiac surgery in a pre-structural era

Beyond Calcium: A Holistic Approach to Optimizing Outcomes for Patients with Hypoparathyroidism

Stroke procedural numbers are an unreliable predictor of patient outcomes, finds study

Temporal left ventricular ejection fraction variations and outcomes in wide population of cardiovascular patients with and without heart failure

Predictors for long-term outcome of pulmonary valve perforation and balloon valvuloplasty in neonates with critical pulmonary valve stenosis or pulmonary valve atresia with intact ventricular septum

Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta‐analysis

The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experience”

Sedentary Behavior and Light-Intensity Physical Activity During Pregnancy and Cardiovascular Health: A Science Advisory From the American Heart Association

Early and late clinical outcomes and cost-effectiveness of aortic valve replacement using the Inspiris Resilia bioprosthesis

Impact of HFpEF on Ablation Outcomes; PVI Only Ablation in HFrEF?

Patient-Reported Outcomes as End Points in Heart Failure Trials

SUMMIT: No Impact From Baseline eGFR on HF Outcomes With Tirzepatide

Better Cognitive Outcomes Tied to Vigorous Exercise in Hypertensive Adults

New approach to defibrillation may improve cardiac arrest outcomes

Hearing Loss and Heart Failure; Improved TAVR Outcomes

Blood pressure trial intervention shows mixed outcomes in chronic kidney disease patients

Chest pain and computer ‘normal’ ECG. Wait for troponin? And what is the reference standard for ECG diagnosis? Cardiologist or outcome?

Renal Outcomes Seem to Differ By Gender After Living Kidney Donation

Poor Hepatitis D Screening in HBV Patients Impacts Survival Outcomes

Combined Tacrolimus, Belatacept Regimen Improves Post-Kidney Transplant Outcomes

Optimizing Psychological Health Across the Perinatal Period: An Update on Maternal Cardiovascular Health: A Scientific Statement From the American Heart Association

Interventions for adult congenital heart disease

Patients Who Received Ross Procedure Demonstrate Excellent Survival Rates after 20 Years

Insulin Beats Oral Alternatives for Gestational Diabetes Outcome

Surgical and transcatheter aortic valve interventions for aortic stenosis in England: sociodemographic variations in treatment trends and outcome over 20 years

Aquatic Exercise Improves Physical, Psychosocial Outcomes in People With ME/CFS

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