Outcomes - Cardiovascular Update

Amyloidosis Drug Improves Outcomes, Survival

Med Page Today

AUGUST 30, 2024

(MedPage Today) -- LONDON -- Vutrisiran (Amvuttra) improved functional and disease outcomes as well as survival in transthyretin amyloidosis cardiomyopathy (ATTR-CM), according to findings from the HELIOS-B phase III trial. And the benefits.

Outcomes

Outcomes Cardiomyopathy

Finerenone improves outcomes in HFmrEF and HFpEF

Nature Reviews - Cardiology

SEPTEMBER 18, 2024

Nature Reviews Cardiology, Published online: 19 September 2024; doi:10.1038/s41569-024-01087-x The non-steroidal mineralocorticoid receptor antagonist finerenone reduces the risk of adverse outcomes in patients with heart failure with mildly reduced ejection fraction or with preserved ejection fraction, according to findings presented at the ESC Congress (..)

Preserved Ejection Fraction

Preserved Ejection Fraction Outcomes Heart Failure

Outcomes of Class Switching vs Cycling TNF Inhibitors

HCPLive

SEPTEMBER 19, 2024

Panelists discuss how switching to a biologic with a different mechanism of action can enhance clinical outcomes in patients with inadequate responses to tumor necrosis factor inhibitors.

Outcomes

After Adverse Pregnancy Outcomes, Mortality Risk Lingers for Decades

Med Page Today

APRIL 15, 2024

(MedPage Today) -- Women who experienced major adverse pregnancy outcomes still had increased mortality risks decades later, a population-based cohort study of Swedish data found. Adverse pregnancy outcomes independently associated with increased.

Outcomes

Artificial blood vessels could improve heart bypass outcomes

Science Daily - Heart Disease

JULY 25, 2024

Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

Outcomes

Outcomes Cardiovascular Disease Technology

Artificial blood vessels could improve heart bypass outcomes

Medical Xpress - Cardiology

JULY 25, 2024

Strong, flexible, gel-like tubes—created using a novel 3D printing technology—could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

Outcomes

Outcomes Technology

Deucravacitinib Superior to Apremilast in Patient-Reported Outcomes for Psoriasis

HCPLive

AUGUST 10, 2024

In this analysis, investigators compared deucravacitinib in terms of patient-reported outcomes versus those of placebo and apremilast.

Outcomes

Heart Disease Outcomes Better When Anxiety, Depression Are Treated

Med Page Today

MARCH 21, 2024

(MedPage Today) -- In people with heart disease and comorbid anxiety or depression, mental health treatment showed strong links to better clinical outcomes in an observational analysis of the Ohio Medicaid database. Those hospitalized with coronary.

Heart Disease

Heart Disease Medicaid Outcomes Hospital

Valvular and perivalvular thrombus after TAVR: Risks and Outcomes

Cardiology Update

FEBRUARY 26, 2024

This sub-study aimed to assess the frequency of both valvular (subclinical leaflet thrombus) and perivalvular (supravalvular, subvalvular, and sinus of Valsalva) thrombus and their potential association with various clinical outcomes. had thrombus at any aortic valve complex. Specifically, 14.2% had perivalvular thrombus.

TAVR

TAVR Aortic valve Outcomes Aortic

Impact of untreated CAD on TAVR outcomes

Cardiology Update

JANUARY 28, 2024

In a recent study published in the European Heart Journal, researchers investigated the influence of varying degrees and extent of untreated chronic obstructive CAD on TAVR outcomes and longer-term results. The post Impact of untreated CAD on TAVR outcomes appeared first on Cardiology Update. Original article: Persits I et al.

TAVR

TAVR Aortic valve Outcomes Coronary Artery Disease

Impact of Diabetes on Outcomes in Left Main Coronary Revascularization: PCI vs. CABG

Cardiology Update

MARCH 25, 2024

Left main coronary artery disease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes. Original article: Gaba P et al. Circulation.

Diabetes

Diabetes Coronary Artery Bypass Graft Outcomes Coronary Artery Disease

TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk. Severe SVD was defined by specific criteria.

Aortic valve

Aortic valve Aortic Outcomes Thrombosis

Rapid Uptitration of GDMT and HF Outcomes

American College of Cardiology

JULY 22, 2024

What is the relationship between intensive uptitration of guideline-directed medical therapy (GDMT) for heart failure (HF) during the early post-discharge period, and what are the outcomes?

Outcomes

Outcomes Heart Failure Article

Nonsteroidal MRA Improves Outcomes in HFpEF, HFmrEF

Med Page Today

SEPTEMBER 1, 2024

(MedPage Today) -- LONDON -- The nonsteroidal mineralocorticoid receptor antagonist (MRA) finerenone (Kerendia) improved outcomes driven by soft endpoints in patients with heart failure and mildly reduced or preserved ejection fraction (HFmrEF.

Preserved Ejection Fraction

Preserved Ejection Fraction Outcomes Heart Failure

COPD, IPF Linked to More Severe COVID-19 Outcomes, Mortality Risk

HCPLive

APRIL 1, 2024

New data show COPD and IPF, among other interstitial lung diseases, are more significantly associated with poor 30-day outcomes from COVID-19 than asthma.

COVID-19

COVID-19 Outcomes

Balloon Angioplasty 'Lite' Improves Key Intracranial Stenosis Outcomes

Med Page Today

SEPTEMBER 5, 2024

(MedPage Today) -- Submaximal balloon angioplasty for symptomatic intracranial atherosclerotic stenosis (ICAS) improved outcomes over aggressive medical management alone, the BASIS trial from China showed. The incidence of the composite of any.

Angioplasty

Angioplasty Stenosis Outcomes

High-Impact Chronic Pain in Sickle Cell Linked to Poor Health Outcomes

HCPLive

JUNE 7, 2024

High-impact chronic pain is a severely affected subgroup in SCD and is associated with greater pain burden and worse health outcomes.

Outcomes

Electrocardiographic predictors of clinical outcomes in non-ischemic cardiomyopathy patients with left bundle branch area pacing cardiac resynchronization therapy

HeartRhythm

SEPTEMBER 12, 2024

It remains unclear whether electrocardiographic changes observed during LBBAP can predict clinical outcomes. Paced QRS morphology may vary during left bundle branch area pacing (LBBAP) as per the pacing location.

Outcomes

Outcomes Cardiomyopathy

Iron Deficiency Linked to Poor Outcomes in Kidney Transplant Recipients

HCPLive

MARCH 19, 2024

Iron deficiency, independent of anemia, may be a potentially modifiable target to improve patient-reported outcomes after kidney transplantation.

Transplant

Transplant Outcomes

Stress and substance use disorders: risk, relapse, and treatment outcomes

Journal of Clinical Investigation - Cardiology

AUGUST 15, 2024

Finally, the prevention and treatment implications of targeting this “stress pathophysiology of addiction” are discussed, along with specific aspects that may be targeted in intervention development to rescue stress-related alterations in drug motivation and to improve SUD treatment outcomes.

Outcomes

Outcomes Research

Optimal Medical Therapy and Outcomes in Chronic HFrEF

American College of Cardiology

AUGUST 8, 2024

What are the outcomes in patients with chronic heart failure and reduced ejection fraction (HFrEF) as determined by their optimal medical therapy (OMT) score?

Outcomes

Outcomes Heart Failure Article

SECURE: Restrictive Cholecystectomy Strategy Shows No Benefit for Pain-Free Outcomes

HCPLive

AUGUST 29, 2024

The restrictive strategy led to fewer cholecystectomies without increasing complications but did not improve pain-free outcomes versus usual care for symptomatic cholelithiasis.

Outcomes

Renal Function Mediates Link Between Lp(a), Adverse Cardiovascular Outcomes

HCPLive

MARCH 24, 2024

A significant association between Lp(a) and adverse cardiovascular outcomes was altered by renal function in patients undergoing percutaneous coronary intervention.

Outcomes

Tirzepatide Reduces Heart Failure Outcomes in Obesity-Related Heart Failure

HCPLive

AUGUST 1, 2024

Eli Lilly's tirzepatide showed a 38% reduction in heart failure outcomes and improved symptoms in adults with HFpEF and obesity in the phase 3 SUMMIT trial.

Heart Failure

Heart Failure Obesity Outcomes

Blood thinners added to clot-busting medication did not improve stroke outcomes

American Heart News - Stroke News

FEBRUARY 7, 2024

Research Highlights: Although giving blood thinners along with clot-busting medication may help in treating heart attacks, it did not improve 90-day outcomes in people with clot-caused strokes. Enrollment in a large clinical trial, which had been.

Heart attacks

Heart attacks Heart Attack Outcomes Strokes

Faricimab Provides Similar nAMD, DME Outcomes at Significantly Fewer Injections

HCPLive

DECEMBER 31, 2023

A systematic review and meta-analysis suggests the dual pathway-targeting faricimab provides some greater benefit in outcomes like CST at fewer injections and without compromise of safety to anti-VEGF monotherapies.

Outcomes

Artificial Intelligence Speeds Up Heart Scans, Leading to Efficiency and Improving Outcomes

DAIC

JULY 12, 2024

Garg said: “The AI model precisely determined the size and function of the heart's chambers and demonstrated outcomes comparable to those acquired by doctors manually but much quicker. This is paving the way for faster, non-invasive and more accurate diagnosis of heart failure and other cardiac conditions.

Outcomes

Outcomes Hospital Research Innovation

Transcatheter Valve Replacement Outcomes Similar to Surgery in Long-Term Analysis

DAIC

MAY 15, 2024

In the meta-analysis of seven randomized trials, published in JSCAI and presented at the 2024 EuroPCR conference in Paris, France, researchers compared the outcomes of 7,785 patients undergoing TAVR (a procedure that delivers a new aortic valve into the heart through a catheter) to those undergoing SAVR for severe aortic stenosis.

Aortic valve

Aortic valve TAVR Outcomes Aortic

In Heart Failure, Thinking Care Will Be Unaffordable May Mean Poorer Outcomes

Med Page Today

MARCH 21, 2024

(MedPage Today) -- How patients with acute decompensated heart failure (HF) perceived the financial challenges of their healthcare played out in their health outcomes, despite receiving life-prolonging medications, a prospective study from China.

Heart Failure

Heart Failure Outcomes

20 mm vs. â‰¥23 mm Balloon-Expandable TAVR Outcomes

American College of Cardiology

AUGUST 21, 2024

Among patients undergoing transcatheter aortic valve replacement (TAVR) with a balloon-expandable valve (BEV), what are the 3-year clinical outcomes associated with a small (20 mm) compared to a larger (â‰¥23 mm) device, and is there a relationship between the discharge echocardiographic (echo) mean gradient (MG) and measured or predicted thresholds (..)

TAVR

TAVR Aortic valve Outcomes Aortic

Intravascular Lithotripsy Outcomes in Contemporary PCI

American College of Cardiology

JULY 8, 2024

What are the trends and outcomes of coronary intravascular lithotripsy (IVL), rotational/orbital atherectomy, or both among patients who underwent percutaneous coronary intervention (PCI) in Michigan?

Outcomes

Outcomes Article

Optimizing Treatment Outcomes in Retinal Vein Occlusion (RVO)

HCPLive

AUGUST 14, 2024

A panel of ophthalmologists discuss strategies for improving patient outcomes in retinal vein occlusion with anti-VEGF and other therapies.

Outcomes

Outcomes of AF Ablation Among Older Adults in the US

American College of Cardiology

AUGUST 8, 2024

What are the patient characteristics, population rates, and 30-day outcomes of pulmonary vein isolation (PVI) in a nationwide sample of US adults aged >65 years?

Outcomes

Outcomes Ablation Pulmonary Article

Optimizing Treatment Outcomes in Retinal Vein Occlusion

HCPLive

AUGUST 1, 2024

A panel of ophthalmologists discuss strategies for improving patient outcomes in retinal vein occlusion with anti-VEGF and other therapies.

Outcomes

Percutaneous Edge-to-Edge Repair for TR: TRILUMINATE 3-Year Outcomes

American College of Cardiology

SEPTEMBER 11, 2024

What are the 3-year outcomes of tricuspid transcatheter edge-to-edge repair (T-TEER) with the TriClip implant for the treatment of severe symptomatic tricuspid regurgitation (TR)?

Tricuspid

Tricuspid Outcomes Article

Qazi Corner, Edition 6: Bariatric Surgery in Liver Disease, Glucagon, and Cuffitis Outcomes

HCPLive

JUNE 6, 2024

The second quarterly issue of 2024 reviews outcomes in liver disease after bariatric surgery, glucagon’s role in esophageal impaction management, and outcomes after cuffitis following pouch creation.

Outcomes

Treatment and Patient Reported Outcomes in Atopic Dermatitis

HCPLive

JULY 22, 2024

Christopher Bunick, MD, PhD, examines patient satisfaction upon achieving primary study endpoints in clinical trials and highlights the significance of patient-reported outcomes (PROs) in both clinical trial designs and patient care.

Outcomes

Outcomes Patient Care

Comparing Cardiovascular and Kidney Outcomes with Tirzepatide vs. GLP-1 Agonists

NEJM Journal Watch - Cardiology

AUGUST 15, 2024

This retrospective study showed lower incidence for several adverse outcomes with tirzepatide, with some caveats.

Outcomes

Midterm outcomes of transcatheter aortic valve replacement in patients with active cancer

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

Aortic valve

Aortic valve Cancer Aortic TAVR

Predictors and 5-Year Outcomes of Pacemaker After TAVR

American College of Cardiology

JUNE 13, 2024

What are the rates of a permanent pacemaker (PPM) implantation, the predictors of needing a PPM, and long-term clinical outcomes of the third-generation balloon-expandable SAPIEN 3 (S3) transcatheter heart valve (THV)?

Pacemaker

Pacemaker TAVR Outcomes Heart Valves

Automated AKI Alert Prompts Change of Care, Shows No Impact on Patient Outcomes

HCPLive

JANUARY 26, 2024

Use of the electronic AKI alert system led to slight improvements in intervention rates and AKI diagnosis, although kidney function and patient-centered outcomes did not differ from patients receiving usual care.

Outcomes

No Improved Outcomes for HF Patients With Sleep Apnea Using ASV Breathing Devices

Med Page Today

DECEMBER 29, 2023

(MedPage Today) -- Breathing machines with adaptive servo-ventilation (ASV) did not improve survival or other clinical outcomes in patients with heart failure (HF) and reduced ejection fraction and sleep-disordered breathing, the phase III ADVENT.

Outcomes

Outcomes Heart Failure

Allogeneic Stem Cell Therapy Falls Short on Stroke Outcomes

Med Page Today

JANUARY 17, 2024

(MedPage Today) -- Bone marrow-derived allogeneic stem cell therapy shortly after ischemic stroke did not improve outcomes at 90 days, a phase II/III randomized clinical trial known as TREASURE found. The rate of excellent outcomes -- a composite.

Outcomes

Outcomes Strokes Stroke

Predicting Long-Term Clinical Outcomes in Recurrent Pericarditis

American College of Cardiology

SEPTEMBER 16, 2024

What are the factors associated with long-term outcomes in patients with recurrent pericarditis?

Pericarditis

Pericarditis Outcomes Article

Amyloidosis Drug Improves Outcomes, Survival

Finerenone improves outcomes in HFmrEF and HFpEF

Outcomes of Class Switching vs Cycling TNF Inhibitors

After Adverse Pregnancy Outcomes, Mortality Risk Lingers for Decades

Artificial blood vessels could improve heart bypass outcomes

Artificial blood vessels could improve heart bypass outcomes

Deucravacitinib Superior to Apremilast in Patient-Reported Outcomes for Psoriasis

Heart Disease Outcomes Better When Anxiety, Depression Are Treated

Valvular and perivalvular thrombus after TAVR: Risks and Outcomes

Impact of untreated CAD on TAVR outcomes

Impact of Diabetes on Outcomes in Left Main Coronary Revascularization: PCI vs. CABG

TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Rapid Uptitration of GDMT and HF Outcomes

Nonsteroidal MRA Improves Outcomes in HFpEF, HFmrEF

COPD, IPF Linked to More Severe COVID-19 Outcomes, Mortality Risk

Balloon Angioplasty 'Lite' Improves Key Intracranial Stenosis Outcomes

High-Impact Chronic Pain in Sickle Cell Linked to Poor Health Outcomes

Electrocardiographic predictors of clinical outcomes in non-ischemic cardiomyopathy patients with left bundle branch area pacing cardiac resynchronization therapy

Iron Deficiency Linked to Poor Outcomes in Kidney Transplant Recipients

Stress and substance use disorders: risk, relapse, and treatment outcomes

Optimal Medical Therapy and Outcomes in Chronic HFrEF

SECURE: Restrictive Cholecystectomy Strategy Shows No Benefit for Pain-Free Outcomes

Renal Function Mediates Link Between Lp(a), Adverse Cardiovascular Outcomes

Tirzepatide Reduces Heart Failure Outcomes in Obesity-Related Heart Failure

Blood thinners added to clot-busting medication did not improve stroke outcomes

Faricimab Provides Similar nAMD, DME Outcomes at Significantly Fewer Injections

Artificial Intelligence Speeds Up Heart Scans, Leading to Efficiency and Improving Outcomes

Transcatheter Valve Replacement Outcomes Similar to Surgery in Long-Term Analysis

In Heart Failure, Thinking Care Will Be Unaffordable May Mean Poorer Outcomes

20 mm vs. â‰¥23 mm Balloon-Expandable TAVR Outcomes

Intravascular Lithotripsy Outcomes in Contemporary PCI

Optimizing Treatment Outcomes in Retinal Vein Occlusion (RVO)

Outcomes of AF Ablation Among Older Adults in the US

Optimizing Treatment Outcomes in Retinal Vein Occlusion

Percutaneous Edge-to-Edge Repair for TR: TRILUMINATE 3-Year Outcomes

Qazi Corner, Edition 6: Bariatric Surgery in Liver Disease, Glucagon, and Cuffitis Outcomes

Treatment and Patient Reported Outcomes in Atopic Dermatitis

Comparing Cardiovascular and Kidney Outcomes with Tirzepatide vs. GLP-1 Agonists

Midterm outcomes of transcatheter aortic valve replacement in patients with active cancer

Predictors and 5-Year Outcomes of Pacemaker After TAVR

Automated AKI Alert Prompts Change of Care, Shows No Impact on Patient Outcomes

No Improved Outcomes for HF Patients With Sleep Apnea Using ASV Breathing Devices

Allogeneic Stem Cell Therapy Falls Short on Stroke Outcomes

Predicting Long-Term Clinical Outcomes in Recurrent Pericarditis

Stay Connected