Circulation

MARCH 31, 2024

Circulation, Volume 149, Issue 14 , Page 1139-1144, April 2, 2024.

Circulation 45

Circulation 45

Medical Xpress - Cardiology

APRIL 15, 2024

An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrial fibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.

Atrial Fibrillation 111

Atrial Fibrillation Circulation Research 111

Journal of the American Heart Association

MARCH 18, 2024

In this review, we provide a detailed overview of BCAA metabolism, focus on molecular mechanisms linking disrupted BCAA homeostasis with cardiometabolic disease, summarize the evidence from observational and interventional studies investigating associations between circulating BCAAs and cardiometabolic disease, and offer valuable insights into the (..)

Circulation 40

Circulation Obesity Heart Failure Cardiovascular Disease 40

Circulation

DECEMBER 27, 2023

Circulation, Volume 149, Issue 1 , Page 1-3, January 2, 2024.

Circulation 49

Circulation 49

Circulation

FEBRUARY 19, 2024

Circulation, Volume 149, Issue 8 , Page 627-632, February 20, 2024.

Circulation 45

Circulation 45

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension 132

Hypertension Circulation Blood Pressure Research 132

Hypertension Journal

FEBRUARY 9, 2024

BACKGROUND:High circulating DPP3 (dipeptidyl peptidase 3) has been associated with poor prognosis in critically ill patients with circulatory failure. Hypertension, Ahead of Print. In such situation, DPP3 could play a pathological role, putatively via an excessive angiotensin peptides cleavage.

Circulation 40

Circulation Blood Pressure Hypertension 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 5 However, most of the existing literature focuses on anterior circulation. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Stents 40

Stents Stent Circulation Stroke 40

Circulation

FEBRUARY 25, 2024

Circulation, Volume 149, Issue 9 , Page 717-721, February 27, 2024.

Circulation 40

Circulation 40

Circulation

JANUARY 7, 2024

Circulation, Volume 149, Issue 2 , Page 155-159, January 9, 2024.

Circulation 45

Circulation 45

Circulation

DECEMBER 17, 2023

Circulation, Volume 148, Issue 25 , Page 2058-2063, December 19, 2023.

Circulation 45

Circulation 45

JAMA Cardiology

JANUARY 2, 2024

This genetic association study investigates if mendelian randomization can identify associations between circulating cardiovascular disease–related proteins and hypertensive disorders of pregnancy.

Circulation 40

Circulation Hypertension Cardiovascular Disease 40

Stroke Journal

FEBRUARY 1, 2024

These techniques have been derived from studies of anterior-circulation stroke and not yet validated in posterior circulation stroke (PCS). Twenty-seven-patients with baseline multimodal-CT with occlusion of a large posterior-circulation (PC) artery and follow up diffusion-weighted-MRI at 24-48 hours were included.

Circulation 40

Circulation Stroke Strokes 40

Hypertension Journal

FEBRUARY 16, 2024

Such stress alters the content and increases the release of syncytiotrophoblast extracellular vesicles (STB-EVs) into the maternal circulation. We quantified 5′-tRFs from circulating STB-EVs using a placental alkaline phosphatase immunoassay. 5′-tRFs are produced in response to stress.

Circulation 45

Circulation Hypertension 45

Circulation: Cardiovascular Imaging

JANUARY 15, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e016453, January 1, 2024.

Circulation 40

Circulation Cardiovascular Imaging 40

Stroke Journal

APRIL 3, 2024

Steno-occlusive changes in the posterior cerebral arteries (PCAs) may contribute to worsened outcomes in patients with MMD; however, there is little information on the incidence and natural history of posterior circulation MMD (PCMMD).

Circulation 40

Circulation Outcomes Academic Atherosclerosis 40

Stroke Journal

JANUARY 4, 2024

These studies mainly concerned anterior circulation occlusions. All patients with a posterior circulation occlusion were included. Our results are in line with the literature on the anterior circulation. Primary outcome was a shift toward better functional outcome on the modified Rankin Scale at 90 days.

Thrombolysis 40

Thrombolysis Circulation Hemorrhage Ischemia 40

Circulation

DECEMBER 21, 2023

Circulation, Ahead of Print.

Circulation 49

Circulation 49

Cardiovascular Diabetology

FEBRUARY 8, 2024

Circulating levels of microRNAs are increasingly re. Coronary microvascular dysfunction (CMD) is a frequent complication of diabetes mellitus (DM) characterized by challenges in both diagnosis and intervention.

Circulation 52

Circulation Diabetes Research 52

Stroke Journal

JANUARY 30, 2024

We also developed parabioses between tPANulland wild-type mice (tPAWT), anticipating that a tPAWTdonor would restore levels of tPA to normal ones, in the circulation but not in the brain parenchyma of a tPANullrecipient. In this context, the impact of endogenous parenchymal tPA is limited.

Circulation 40

Circulation Stroke Strokes Embolism 40

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2024

In this review, we summarize the diagnostic and prognostic tools for ICI-myocarditis, including electrocardiography, echocardiography, cardiac magnetic resonance imaging, with emphasis on circulating biomarkers.

Biomarkers 64

Biomarkers Circulation Cancer Outcomes 64

Heart BMJ

MARCH 22, 2024

Objective In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH agents on different exercise parameters in stable Fontan patients by synthesising evidence of randomised controlled trials (RCTs).

Exercise 40

Exercise Circulation Pulmonary Pharmacology 40

Stroke Journal

MARCH 6, 2024

BACKGROUND:Inflammatory type focal cerebral arteriopathy (FCA-i) in the anterior circulation (AC) is well characterized, and the focal cerebral arteriopathy severity score (FCASS) reflects the severity of the disease.

Circulation 40

Circulation Pediatrics Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

The Clot Burden Score (CBS) is a semiquantitative measure on CT angiography (CTA) of thrombus extent in proximal anterior circulation strokes that has been correlated with functional outcome. Higher clot burden has also been shown to have lower recanalization rates with intravenous thrombolytics.

Circulation 40

Circulation Stroke Strokes Outcomes 40

Journal of the American Heart Association

JANUARY 12, 2024

We aimed to perform 2‐sample Mendelian randomization (MR) analyses to assess the causal association between circulating cytokines/growth factors and CAD.Methods and ResultsThe instrumental variables for 28 circulating cytokines and growth factors were identified from a genome‐wide association study of 8293 European participants.

Coronary Artery Disease 40

Coronary Artery Disease Circulation 40

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Conclusions Circulating ERFE is higher in patients with ADHF than in other causes of new onset breathlessness with fair diagnostic utility, performing better in Asian than in Western patients. The diagnostic performance of ERFE is impaired in patients with AF but not patients with obesity.

Heart Failure 59

Heart Failure Circulation Obesity Atrial Fibrillation 59

Stroke Journal

FEBRUARY 1, 2024

Background and Purpose:Notoriously difficult to recognize, posterior circulation strokes (PCS) can be some of the most devastating. A PSC with tele-stroke coverage and ongoing education improved identification of posterior circulation strokes and outcomes. Stroke, Volume 55, Issue Suppl_1 , Page ATP53-ATP53, February 1, 2024.

Circulation 40

Circulation Stroke Strokes Education 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, the vertebral‐basilar anatomy is more challenging for MT compared to the anterior circulation due to several congenital variants such as hypoplastic vertebral artery, fenestration on the vertebrobasilar junction, or chronic asymptomatic occlusions of vertebral arteries, and tortuous subclavian arteries and vertebral arteries (VAs).

Circulation 40

Circulation Anatomy Congenital Stroke 40

Stroke Journal

FEBRUARY 1, 2024

We developed an ED triage diagnostic algorithm termed, “Dizzy-7”, based on evidence incorporating key history and physical examination elements derived in patients with acute posterior circulation ischemia.

Circulation 40

Circulation Stroke Strokes Education 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, there is limited evidence regarding its safety and efficacy specifically for distal aneurysms of the posterior circulation including posterior inferior cerebellar artery (PICA), anterior inferior cerebellar artery (AICA), superior cerebellar artery (SCA), and the P2 and P3 segment of the posterior cerebral artery (PCA).

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionFlow diverters have demonstrated reliable safety and effectiveness for the treatment of selected anterior circulation intracranial aneurysms. However, posterior circulation aneurysms comprise around 10‐15% of all aneurysms, and they frequently present atypical morphological and anatomical characteristics.

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Previous studies suggest that the DHV sign was associated with early recurrent ischemic stroke in the anterior circulation secondary to intracranial atherosclerotic disease (ICAD). However, its significance in ischemic stroke in the posterior circulation is unknown.

Circulation 40

Circulation Outcomes Stenosis Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Posterior circulation tandem occlusion was defined as stroke due to intracranial vertebral (V4), basilar, or posterior cerebral artery (PCA) occlusions, with tandem steno-occlusive lesion >70% of the extracranial vertebral artery and impaired distal flow or partial filling of the VA from collaterals.

Circulation 40

Circulation Outcomes Thrombolysis Hemorrhage 40

Journal of the American Heart Association

MARCH 8, 2024

This approach allowed us to evaluate the effect of childhood body size on 11 measures of right heart and pulmonary circulation independent of other anthropometric traits at various stages in the lifecourse. 0.33];P=3×10−7) independent of adulthood body size.

Pulmonary 40

Pulmonary Circulation Physiology 40

Frontiers in Cardiovascular Medicine

JANUARY 23, 2024

Background The relationship between ketone bodies (KB) and mortality in patients with heart failure (HF) syndrome has not been well established.

Heart Failure 64

Heart Failure Circulation 64

Stroke Journal

FEBRUARY 1, 2024

Background/Purpose:Fast progressors (FP) of infarct growth in anterior circulation large vessel occlusions (LVO) may be prevalent in the <6h period depending on how it is defined. Stroke, Volume 55, Issue Suppl_1 , Page ATP130-ATP130, February 1, 2024. Median IGR for the cohort was 3.8mL/h (0-16.4). 14 of these (45.2%, 95% CI: 24.7-75.8%)

Circulation 40

Circulation Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Computerized tomography perfusion (CTP) imaging serves as a valuable modality for the assessment of individuals with a large vessel anterior circulation stroke. Stroke, Volume 55, Issue Suppl_1 , Page ATP141-ATP141, February 1, 2024.

Circulation 40

Circulation Stroke Strokes 40