Circulation - Cardiovascular Update

Highlights From the Circulation Family of Journals

Circulation

JULY 21, 2024

Circulation, Volume 150, Issue 4 , Page 336-339, July 23, 2024.

Circulation

Circulating microRNAs as biomarkers of Chagas cardiomyopathy

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Methods We carried out a case-control study to identify circulating miRNAs associated with CHCM. We performed a clinical, echocardiographic, and laboratory evaluation and profiled circulating miRNA in the serum samples. Results Differences between groups were observed in clinical variables and in the analysis of miRNAs.

Cardiomyopathy

Cardiomyopathy Circulation Biomarkers Laboratory

Researchers identify circulating proteins linked to preeclampsia and other hypertensive disorders of pregnancy

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension

Hypertension Circulation Blood Pressure Research

Study Suggests COPD Preventative Measures Needed During Seasonal Virus Circulations

HCPLive

JUNE 7, 2024

These data indicate the benefits of implementing individual protective measures in winter by patients with COPD.

Circulation

Circulating biomolecules identify patients with atrial fibrillation at high risk of cardiovascular events

Medical Xpress - Cardiology

APRIL 15, 2024

An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrial fibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.

Atrial Fibrillation

Atrial Fibrillation Circulation Research

Circulating palmitoyl sphingomyelin levels predict the 10-year increased risk of cardiovascular disease death in Chinese adults: findings from the Da Qing Diabetes Study

Cardiovascular Diabetology

JANUARY 19, 2024

Whether circulating PSM levels. Higher levels of palmitoyl sphingomyelin (PSM, synonymous with sphingomyelin 16:0) are associated with an increased risk of cardiovascular disease (CVD) in people with diabetes.

Cardiovascular Disease

Cardiovascular Disease Circulation Diabetes Research

Highlights From the Circulation Family of Journals

Circulation

JANUARY 12, 2025

Circulation, Volume 151, Issue 2 , Page 188-192, January 14, 2025.

Circulation

Recognized Outstanding Reviewers for Circulation in 2024

Circulation

JANUARY 12, 2025

Circulation, Volume 151, Issue 2 , Page 125-125, January 14, 2025.

Circulation

Poor blood circulation: How to prevent it, how to spot it

Medical Xpress - Cardiology

OCTOBER 7, 2024

Pain, tingling and cramps in your legs and feet may be giving you a warning.

Circulation

Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation

Cardiovascular Diabetology

JANUARY 7, 2025

We aimed to investigate the relationship between circulating apoCIII levels and. Preclinical studies suggest that a triglyceride (TG)-independent proinflammatory action of apolipoprotein C-III (apoCIII) exists.

Circulation

Circulation Biomarkers Research

Systemic Circulation in Advanced Heart Failure and Cardiogenic Shock: State-of-the-Art Review

Circulation: Heart Failure

JANUARY 20, 2025

Circulation: Heart Failure, Ahead of Print. The integrative physiology of the left ventricle and systemic circulation is fundamental to our understanding of advanced heart failure and cardiogenic shock. In simplest terms, any increase in aortic stiffness increases the vascular afterload presented to the failing left ventricle.

Cardiogenic Shock

Cardiogenic Shock Heart Failure Circulation Physiology

Early Neurologic Deterioration and Efficacy of Dual Antiplatelet in Anterior Versus Posterior Circulation Stroke

Journal of the American Heart Association

JANUARY 23, 2025

BackgroundAnterior circulation stroke (ACS) differs from posterior circulation stroke (PCS) in several aspects. Journal of the American Heart Association, Ahead of Print. The occurrence of END was higher in ACS than PCS (6.8% versus 3.8%,P=0.007). to 0.8%],P=0.004), but not in PCS (risk difference [95% CI]: 0.6% [2.7% to 1.5%],P=0.57).

Circulation

Circulation Stroke Strokes Outcomes

Efficacy and Safety of Finerenone in Patients With Primary Aldosteronism: A Pilot Randomized Controlled Trial

Circulation

JANUARY 12, 2025

Circulation, Volume 151, Issue 2 , Page 196-198, January 14, 2025.

Circulation

Gut microbial pathway identified as target for improved heart disease treatment

Medical Xpress - Cardiology

AUGUST 20, 2024

The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

Heart Disease

Heart Disease Cardiovascular Disease Circulation Research

Uric Acid Levels Pose Potential Harm in Accelerating Biological Aging

HCPLive

AUGUST 24, 2024

A new study suggests circulating uric acid may be a pro-aging factor in older adults, potentially causing more harm than benefits.

Circulation

The human heart may have a hidden ability to repair itself

Medical Xpress - Cardiology

NOVEMBER 21, 2024

This is according to a new study from Karolinska Institutet published in the journal Circulation. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.

Heart Failure

Heart Failure Circulation

Correction to: Circulating miRNAs and Machine Learning for Lateralizing Primary Aldosteronism

Hypertension Journal

JANUARY 14, 2025

Hypertension, Volume 82, Issue 2 , Page e4-e4, February 1, 2025.

Circulation

Circulation Hypertension

Inching Toward a Blood Test for Hypertrophic Cardiomyopathy

Med Page Today

NOVEMBER 11, 2024

(MedPage Today) -- A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From proteomic profiling of nearly.

Cardiomyopathy

Cardiomyopathy Biomarkers Circulation Research

Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity

Cardiovascular Diabetology

MAY 17, 2024

Growth differentiation factor 15 (GDF15) is a mitokine, the role of which, total or H-specific, in modulating energy metabolism and homeostasis in obesity-related diseases, such as metabolic dysfunction associ.

Obesity

Obesity Circulation Research

Cardiovascular and Metabolic Effects of Modulating Circulating Ketone Bodies With 1,3‐Butanediol in Patients With Heart Failure With Reduced Ejection Fraction

Journal of the American Heart Association

DECEMBER 24, 2024

Secondary end points were stroke volume, heart rate, left ventricular ejection fraction, circulating 3hydroxybutyrate, and free fatty acids. BD treatment provided significant increase in circulating 3hydroxybutyrate by 1400 mol/L (95% CI, 12621538 mol/L,P<0.001) and increased cardiac output by 0.9 L/min (95% CI, 0.71.1

Heart Failure

Heart Failure Circulation Cardiac Function Stroke

Driving Restrictions and Incapacitation Vulnerability Evaluation After ST-Segment–Elevation Myocardial Infarction: DRIVE-STEMI Study

Circulation

JANUARY 20, 2025

Circulation, Volume 151, Issue 3 , Page 282-284, January 21, 2025.

Myocardial Infarction

Myocardial Infarction STEMI Circulation

The effect of empagliflozin on circulating endothelial progenitor cells in patients with diabetes and stable coronary artery disease

Cardiovascular Diabetology

OCTOBER 27, 2024

Diabetes mellitus (DM) is associated with premature atherosclerotic disease, coronary artery disease (CAD) and chronic heart failure (HF), leading to increased morbidity and mortality. Sodium-Glucose Co-transp.

Coronary Artery Disease

Coronary Artery Disease Diabetes Circulation Heart Failure

Circulating growth differentiation factor‐15 levels are associated with early echocardiographic signs of diastolic function impairment in the STANISLAS cohort: A 20‐year follow‐up study

European Journal of Heart Failure

JANUARY 21, 2025

Our study aimed to evaluate whether circulating levels of growth differentiation factor-15 (GDF-15) could predict adverse changes in echocardiographic indexes of cardiac structure and function in an initially healthy populational familial cohort with a long follow-up (STANISLAS cohort).

Circulation

Circulation Blood Pressure Cholesterol Research

Heart muscle can regenerate in some patients, study suggests

Becker's Hospital Review - Cardiology

JANUARY 2, 2025

21 in Circulation. Some heart failure patients with artificial hearts have been able to regenerate heart muscle, potentially paving the way for future heart failure treatment options, according to a study published Nov.

Artificial Heart

Artificial Heart Heart Failure Circulation

New approach to defibrillation may improve cardiac arrest outcomes

Science Daily - Heart Disease

SEPTEMBER 23, 2024

A new observational study suggests the position in which responders initially place the two defibrillator pads on the body may make a significant difference in returning spontaneous blood circulation after shock from a defibrillator.

Defibrillator

Defibrillator Cardiac Arrest Outcomes Circulation

Congenital Heart Surgery: In Rapid Evolution

Circulation

AUGUST 18, 2024

Circulation, Volume 150, Issue 8 , Page 583-585, August 20, 2024.

Congenital

Congenital Circulation

Noninferiority Clinical Trials: Overview for the Clinical Cardiologist

Circulation

SEPTEMBER 8, 2024

Circulation, Volume 150, Issue 11 , Page 823-825, September 10, 2024.

Circulation

Perspectives on Heart Valve Repair

Circulation

AUGUST 25, 2024

Circulation, Volume 150, Issue 9 , Page 661-662, August 27, 2024.

Heart Valves

Heart Valves Circulation

Hot news flash: Menopause can impact a woman's heart health

Medical Xpress - Cardiology

OCTOBER 16, 2024

The menopause transition, those years leading up to and through menopause, is a time of increasing heart disease risk, according to an American Heart Association scientific statement published in the flagship journal Circulation in 2020.

Heart Disease

Heart Disease Circulation

Severe lung infection during COVID-19 can cause damage to the heart

Medical Xpress - Cardiology

MARCH 20, 2024

The research, published in the journal Circulation, specifically looked at damage to the hearts of people with SARS-CoV-2-associated acute respiratory distress syndrome (ARDS), a serious lung condition that can be fatal.

COVID-19

COVID-19 Research Circulation

Blood platelet score detects previously unmeasured risk of heart attack and stroke

Medical Xpress - Cardiology

AUGUST 20, 2024

Platelets are circulating cell fragments known to clump up and form blood clots that stop bleeding in injured vessels.

Heart attacks

Heart attacks Heart Attack Peripheral Arterial Disease Blood Clot

Echocardiography, the AHA, and 100 Years

Circulation

DECEMBER 1, 2024

Circulation, Volume 150, Issue 23 , Page 1819-1822, December 3, 2024.

Circulation

Patients With Advanced Heart Failure and Atrial Fibrillation Deserve an Attempt at Catheter Ablation as First-Line Therapy

Circulation

OCTOBER 13, 2024

Circulation, Volume 150, Issue 16 , Page 1220-1222, October 15, 2024.

Atrial Fibrillation

Atrial Fibrillation Heart Failure Ablation Circulation

Microplastics and Cardiovascular Diseases: Importance of Coexisting Environmental Pollutants

Circulation

SEPTEMBER 15, 2024

Circulation, Volume 150, Issue 12 , Page 908-910, September 17, 2024.

Cardiovascular Disease

Cardiovascular Disease Circulation

The Cardiac Intensive Care Unit at Age 60

Circulation

NOVEMBER 3, 2024

Circulation, Volume 150, Issue 19 , Page 1481-1483, November 5, 2024.

Circulation

Geographic Disparities in Availability of Hospital-Based Cardiac Services Across the United States

Circulation

DECEMBER 25, 2024

Circulation, Volume 151, Issue 1 , Page 123-124, January 7, 2025.

Hospital

Hospital Circulation

Transcatheter Aortic Valve Implantation: Two Decades of a Revolutionary and Ongoing Odyssey

Circulation

SEPTEMBER 8, 2024

Circulation, Volume 150, Issue 11 , Page 821-822, September 10, 2024.

Aortic valve

Aortic valve Aortic Circulation

The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals

Journal of Clinical Investigation - Cardiology

DECEMBER 16, 2024

Furthermore, the two compounds were lower in the circulation of older men, paralleling decreases in lean mass and gait speed. The combination of the two compounds promoted MuSC function in vivo in aged mice and in primary cells isolated from older individuals.

Circulation

Pathogenesis of Atherothrombotic Events: From Lumen to Lesion and Beyond

Circulation

OCTOBER 13, 2024

Circulation, Volume 150, Issue 16 , Page 1217-1219, October 15, 2024.

Circulation

Major breakthrough in hypertension diagnosis could save billions

Medical Xpress - Cardiology

DECEMBER 27, 2023

Their findings were published this week in Circulation. Hunter Medical Research Institute and University of Newcastle researcher Professor Murray Cairns, along with his Precision Medicine team, have discovered a way of predicting who will respond to blood pressure treatments to lower sodium in the body.

Blood Pressure

Blood Pressure Hypertension Research Circulation

Electronic sock detects unhealthy walking style linked to cardiovascular and diabetic complications

Medical Xpress - ECG

APRIL 8, 2024

An electronic sock that detects an unhealthy walking style linked with diabetes and poor circulation shows promise for preventing foot ulcers and amputation. The novel research is set to benefit the many patients with diabetes who have clogged arteries in the legs and is presented for the first time at EHRA 2024.

Diabetes

Diabetes Circulation Research

Link between high levels of niacin -- a common b vitamin -- and heart disease, study suggests

Science Daily - Heart Disease

FEBRUARY 19, 2024

Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.

Heart Disease

Heart Disease Heart attacks Heart Attack Atherosclerosis

Close Family Members or Cosurvivors of Cardiac Arrest Patients Need Support

Circulation

AUGUST 11, 2024

Circulation, Volume 150, Issue 7 , Page 577-579, August 13, 2024.

Cardiac Arrest

Cardiac Arrest Circulation

Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Blood vessels are continually exposed to circulating lipids, and elevation of ApoB-containing lipoproteins causes atherosclerosis. Lipoprotein metabolism is highly regulated by lipolysis, largely at the level of the capillary endothelium lining metabolically active tissues.

Atherosclerosis

Atherosclerosis Chronic Disease Physiology Circulation

Highlights From the Circulation Family of Journals

Circulating microRNAs as biomarkers of Chagas cardiomyopathy

Researchers identify circulating proteins linked to preeclampsia and other hypertensive disorders of pregnancy

Study Suggests COPD Preventative Measures Needed During Seasonal Virus Circulations

Circulating biomolecules identify patients with atrial fibrillation at high risk of cardiovascular events

Circulating palmitoyl sphingomyelin levels predict the 10-year increased risk of cardiovascular disease death in Chinese adults: findings from the Da Qing Diabetes Study

Highlights From the Circulation Family of Journals

Recognized Outstanding Reviewers for Circulation in 2024

Poor blood circulation: How to prevent it, how to spot it

Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation

Systemic Circulation in Advanced Heart Failure and Cardiogenic Shock: State-of-the-Art Review

Early Neurologic Deterioration and Efficacy of Dual Antiplatelet in Anterior Versus Posterior Circulation Stroke

Efficacy and Safety of Finerenone in Patients With Primary Aldosteronism: A Pilot Randomized Controlled Trial

Gut microbial pathway identified as target for improved heart disease treatment

Uric Acid Levels Pose Potential Harm in Accelerating Biological Aging

The human heart may have a hidden ability to repair itself

Correction to: Circulating miRNAs and Machine Learning for Lateralizing Primary Aldosteronism

Inching Toward a Blood Test for Hypertrophic Cardiomyopathy

Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity

Cardiovascular and Metabolic Effects of Modulating Circulating Ketone Bodies With 1,3‐Butanediol in Patients With Heart Failure With Reduced Ejection Fraction

Driving Restrictions and Incapacitation Vulnerability Evaluation After ST-Segment–Elevation Myocardial Infarction: DRIVE-STEMI Study

The effect of empagliflozin on circulating endothelial progenitor cells in patients with diabetes and stable coronary artery disease

Circulating growth differentiation factor‐15 levels are associated with early echocardiographic signs of diastolic function impairment in the STANISLAS cohort: A 20‐year follow‐up study

Heart muscle can regenerate in some patients, study suggests

New approach to defibrillation may improve cardiac arrest outcomes

Congenital Heart Surgery: In Rapid Evolution

Noninferiority Clinical Trials: Overview for the Clinical Cardiologist

Perspectives on Heart Valve Repair

Hot news flash: Menopause can impact a woman's heart health

Severe lung infection during COVID-19 can cause damage to the heart

Blood platelet score detects previously unmeasured risk of heart attack and stroke

Echocardiography, the AHA, and 100 Years

Patients With Advanced Heart Failure and Atrial Fibrillation Deserve an Attempt at Catheter Ablation as First-Line Therapy

Microplastics and Cardiovascular Diseases: Importance of Coexisting Environmental Pollutants

The Cardiac Intensive Care Unit at Age 60

Geographic Disparities in Availability of Hospital-Based Cardiac Services Across the United States

Transcatheter Aortic Valve Implantation: Two Decades of a Revolutionary and Ongoing Odyssey

The muscle stem cell case of Benjamin Button: rejuvenating muscle regenerative capacity through nutraceuticals

Pathogenesis of Atherothrombotic Events: From Lumen to Lesion and Beyond

Major breakthrough in hypertension diagnosis could save billions

Electronic sock detects unhealthy walking style linked to cardiovascular and diabetic complications

Link between high levels of niacin -- a common b vitamin -- and heart disease, study suggests

Close Family Members or Cosurvivors of Cardiac Arrest Patients Need Support

Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice

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