The relationships between inflammatory biomarkers, plaque characteristics, and macrophage clusters in coronary plaque: a quantitative assessment of macrophages based on optical coherence tomography
Frontiers in Cardiovascular Medicine
JUNE 25, 2025
BackgroundQuantitative assessment of macrophage accumulation is appealing in evaluating plaque inflammation. Patients with macrophage clusters showed markedly higher levels of inflammatory biomarkers and plaque vulnerability. Large macrophage clusters were independently associated with high MHR and high lipid plaque burden.
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