HCPLive

APRIL 10, 2024

A trio of experts discuss their perspectives on the recent advancement in pharmacotherapy within the management of hypertrophic cardiomyopathy.

Cardiomyopathy 78

Cardiomyopathy 78

All About Cardiovascular System and Disorders

FEBRUARY 24, 2024

Arrhythmogenic Cardiomyopathy was better known as Arrhythmogenic Right Ventricular Dysplasia or ARVD and sometimes as Arrhythmogenic Right Ventricular Cardiomyopathy or ARVC earlier. A study published in JACC has compared the phenotypic expression and clinical outcomes in patients with arrhythmogenic cardiomyopathy [2].

Cardiomyopathy 52

Cardiomyopathy Chest Pain Heart Transplant Myocardial Infarction 52

American College of Cardiology

MAY 2, 2024

What is the prognostic value of extent of late gadolinium enhancement (LGE) in predicting sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM)?

Sudden Cardiac Death 62

Sudden Cardiac Death Cardiomyopathy Article 62

Frontiers in Cardiovascular Medicine

MARCH 19, 2024

Background Precision medicine in paediatric cardiac channelopathy and cardiomyopathy has a rapid advancement over the past years. Results A total of 31 patients (11 cardiac channelopathy and 20 cardiomyopathy) were recruited. Results A total of 31 patients (11 cardiac channelopathy and 20 cardiomyopathy) were recruited.

Cardiomyopathy 64

Cardiomyopathy 64

American Heart News - Heart News

MAY 8, 2024

WASHINGTON and DALLAS (May 8, 2024) – The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 58

Cardiomyopathy Exercise 58

American College of Cardiology

APRIL 17, 2024

What is the risk of mortality and composite cardiomyopathy-related outcomes associated with predicted deleterious variants in cardiomyopathy-associated genes?

Cardiomyopathy 51

Cardiomyopathy Outcomes Article 51

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Infiltration of the myocardium with various cell types, cytokines and chemokines plays a crucial role in the pathogenesis of cardiomyopathies including inflammatory cardiomyopathies and myocarditis. This review offers a comprehensive overview of the current knowledge of the immune landscape in cardiomyopathies based on etiology.

Cardiomyopathy 81

Cardiomyopathy 81

Frontiers in Cardiovascular Medicine

MARCH 6, 2024

Cardiomyopathy, a heterogeneous pathological condition characterized by changes in cardiac structure or function, represents a significant risk factor for the prevalence and mortality of cardiovascular disease (CVD). Research conducted over the years has led to the modification of definition and classification of cardiomyopathy.

Cardiomyopathy 59

Cardiomyopathy Obesity Diabetes Article 59

The New England Journal of Medicine

JANUARY 10, 2024

The author discusses the epidemiology and clinical presentation of peripartum cardiomyopathy, as well as the mechanistic basis for potential therapeutics.

Cardiomyopathy 68

Cardiomyopathy 68

Nature Reviews - Cardiology

APRIL 22, 2024

Nature Reviews Cardiology, Published online: 23 April 2024; doi:10.1038/s41569-024-01032-y According to data from the IMPROVE-HCM trial, ninerafaxstat is well tolerated by patients with symptomatic non-obstructive hypertrophic cardiomyopathy and improves exercise performance among those who are most symptomatically limited.

Cardiomyopathy 59

Cardiomyopathy Exercise 59

Medical Xpress - Cardiology

JANUARY 14, 2024

Acoramidis yields a significantly better four-step primary hierarchical outcome, including aspects of mortality and morbidity, than placebo for patients with transthyretin amyloid cardiomyopathy, according to a study published in the Jan. 11 issue of the New England Journal of Medicine.

Cardiomyopathy 85

Cardiomyopathy Outcomes 85

Frontiers in Cardiovascular Medicine

MARCH 24, 2024

Diabetic cardiomyopathy (DCM), one of the most serious complications of diabetes mellitus, has become recognized as a cardiometabolic disease. The shift in energy substrate preference in diabetic hearts results in increased oxygen consumption and impaired oxidative phosphorylation, leading to diabetic cardiomyopathy.

Diabetes 64

Diabetes Cardiomyopathy 64

American College of Cardiology

MAY 8, 2024

The following are key points to remember from the 2024 AHA/ACC/multisociety guideline for the management of hypertrophic cardiomyopathy (HCM).

Cardiomyopathy 59

Cardiomyopathy Article 59

All About Cardiovascular System and Disorders

DECEMBER 15, 2023

Idiopathic dilated cardiomyopathy Idiopathic dilated cardiomyopathy is a form of dilated cardiomyopathy with unknown etiology characterised by progressive left ventricular dilatation and systolic dysfunction. The incidence of idiopathic dilated cardiomyopathy varies from 3-10 cases per 100,000 population.

Cardiomyopathy 52

Cardiomyopathy General Cardiology 52

American College of Cardiology

APRIL 24, 2024

What is the penetrance of new dilated cardiomyopathy (DCM) diagnosis in genotype positive (G+) relatives and the factors associated with DCM development?

Cardiomyopathy 48

Cardiomyopathy Article 48

Circulation

DECEMBER 21, 2023

microRNAs translocate into subcellular organelles to modify genes involved in diabetic cardiomyopathy. Malonylation, a posttranslational modification of Ago2, reduced the importing of Ago2 into mitochondria in diabetic cardiomyopathy. BACKGROUND:Diabetes is associated with cardiovascular complications.

Cardiomyopathy 81

Cardiomyopathy Diabetes Circulation 81

The American Journal of Cardiology

JANUARY 30, 2024

Hypertrophic cardiomyopathy (HCM) is a heterogeneous genetic heart disease inherited in an autosomal dominant pattern with an estimated prevalence of …

Cardiomyopathy 71

Cardiomyopathy Heart Disease 71

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Methods We prospectively enrolled consecutive patients with ischaemic (ICM) and dilated (DCM) cardiomyopathy from the outpatient heart failure clinic and healthy individuals. Plasma SN levels were significantly higher in the dilated cardiomyopathy (38.8 ± 27 pmol/L) as compared with the ischaemic cardiomyopathy (19.7 ± 22.6 pmol/L)

Cardiomyopathy 59

Cardiomyopathy Heart Failure Outpatient Biomarkers 59

American College of Cardiology

MAY 1, 2024

What are the baseline characteristics and 1-year outcomes of children and adolescents with cardiomyopathy?

Cardiomyopathy 48

Cardiomyopathy Outcomes Article 48

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 72

Cardiomyopathy Sudden Cardiac Death Heart Failure Article 72

Circulation: Genomic and Precision Medicine

JANUARY 30, 2024

TheRBM20gene was first identified as a dilated cardiomyopathy–linked gene over a decade ago. Clinical studies show that pathogenic variants inRBM20are linked to aggressive dilated cardiomyopathy with early onset heart failure and high mortality. Potential therapeutic strategies to treat RBM20 cardiomyopathy are also discussed.

Cardiomyopathy 58

Cardiomyopathy Heart Failure Circulation 58

Medical Xpress - Cardiology

FEBRUARY 21, 2024

Hypertrophic cardiomyopathy is a genetic condition that occurs in 1 in 500 people. It's often silent but can be a deadly killer.

Cardiomyopathy 75

Cardiomyopathy 75

American College of Cardiology

APRIL 23, 2024

Bailey, MD FACC discuss the primary results from the ARISE-HF study: Selective Aldose Reductase Inhibitor For Diabetic Cardiomyopathy. In this interview, James Januzzi, MD, FACC, and Alison L.

Cardiomyopathy 57

Cardiomyopathy Diabetes Article 57

HeartRhythm

APRIL 30, 2024

Tachycardia-induced cardiomyopathy (TIC) is a unique cardiomyopathy, which is potentially reversible. Due to the presence of tachyarrhythmias in various cardiomyopathies, differentiating TIC from other non-reversible conditions can be challenging.

Cardiomyopathy 40

Cardiomyopathy Tachycardia Transplant Biomarkers 40

The New England Journal of Medicine

MAY 12, 2024

In April 1964, leading cardiologists, cardiovascular surgeons, and pathologists convened in London for a 2-day symposium to discuss a relatively new disease entity that we now know as obstructive hypertrophic cardiomyopathy (HCM).1 1 The proceedings kicked off with a comment by the group’s chairman: “I have never before taken.

Cardiomyopathy 40

Cardiomyopathy Pharmacology 40

DAIC

MAY 9, 2024

The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). Ommen, MD, FACC , medical director of the Mayo Hypertrophic Cardiomyopathy Clinic and chair of the guideline writing committee.

Cardiomyopathy 52

Cardiomyopathy Pediatrics Quality of Life Sudden Cardiac Death 52

DAIC

MARCH 6, 2024

Food and Drug Administration’s ( FDA ) Breakthrough Device Designation for their ECGvision-TTR Technology for early detection of ATTR-Cardiomyopathy. ECGvision-TTR was developed through state-of-the-art deep learning algorithms and offers the unique ability to analyze 12-lead ECG images to detect signatures of ATTR Cardiomyopathy.

Technology 86

Technology Cardiomyopathy Quality of Life Innovation 86

American College of Cardiology

DECEMBER 15, 2023

The following are key points to remember from a state-of-the-art paper on current and evolving multimodality cardiac imaging in managing transthyretin amyloid cardiomyopathy.

Cardiomyopathy 72

Cardiomyopathy Article 72

The New England Journal of Medicine

JANUARY 10, 2024

In patients with transthyretin amyloid cardiomyopathy, the TTR stabilizer acoramidis resulted in a better primary hierarchical outcome (including mortality, morbidity, and function) than placebo.

Cardiomyopathy 71

Cardiomyopathy Outcomes 71

HeartRhythm

APRIL 15, 2024

Endocardial electrogram (EGM) characteristics in non-ischemic cardiomyopathy (NICM) have not been explored adequately for prognostication.

Cardiomyopathy 75

Cardiomyopathy Tachycardia 75

American College of Cardiology

JANUARY 11, 2024

The following are key points to remember from a review of peripartum cardiomyopathy (PPCM).

Cardiomyopathy 71

Cardiomyopathy Article 71

Frontiers in Cardiovascular Medicine

JANUARY 16, 2024

Nevertheless, studies on the long-term outcomes of catheter ablation in patients with dilated cardiomyopathy are limited. Conclusions Therefore, catheter ablation proves to be effective in providing long-term control of atrial fibrillation in patients with dilated cardiomyopathy.

Atrial Fibrillation 64

Atrial Fibrillation Cardiomyopathy Ablation Heart Failure 64

HeartRhythm

FEBRUARY 18, 2024

Pathogenic variants (mutations) in genes encoding these proteins (TPM1 [TPM], TNNT2 [cTnT], TNNI3 [cTnI], and TNNC1 [cTnC]) cause different cardiomyopathy types, including hypertrophic (HCM), dilated (DCM), or restrictive cardiomyopathy (RCM).

Cardiomyopathy 45

Cardiomyopathy 45

HCPLive

APRIL 11, 2024

24 examining trends in incidence and outcomes of emergency department visits related to hypertrophic cardiomyopathy from 2006 to 2019. Ahmad Masri, MD, MS, discusses a study from ACC.24

Cardiomyopathy 52

Cardiomyopathy Outcomes 52

American College of Cardiology

MARCH 20, 2024

Echocardiography-based deep learning model to differentiate constrictive pericarditis and restrictive cardiomyopathy. Commentary based on Chao CJ, Jeong J, Arsanjani R, et al. JACC Cardiovasc Imaging

Pericarditis 62

Pericarditis Cardiomyopathy Article 62

American College of Cardiology

MARCH 19, 2024

What is the prevalence and what are the demographics of patients in the US population that are methamphetamine users and are admitted for cardiomyopathy (CM)?

Cardiomyopathy 46

Cardiomyopathy Hospital Article 46

All About Cardiovascular System and Disorders

MAY 8, 2024

2024 ACC/AHA/Multisociety Guidelines for Management of Hypertrophic Cardiomyopathy is now available online with free access at JACC website. Those who are in a hurry could go through the 2024 Hypertrophic Cardiomyopathy Guideline-at-a-Glance which is a five page document which summarises top ten take home messages from the guidelines.

Cardiomyopathy 40

Cardiomyopathy Download Heart Rhythm Document 40