Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

Hypertrophic cardiomyopathy (HCM) is a genetic disorder in the heart caused by variants in sarcomeric proteins that disrupt myocardial function, leading to hypercontractility, hypertrophy, and fibrosis.

Cardiomyopathy 52

Cardiomyopathy Innovation Cardiac Function Research 52

Med Page Today

MARCH 14, 2024

(MedPage Today) -- The American West has seen the biggest surge of cardiomyopathy-associated hospital admissions among methamphetamine users, based on 13 years of the latest available hospital admission data. The National Inpatient Sample (NIS.

Cardiomyopathy 131

Cardiomyopathy Inpatient Hospital 131

Cardiology Update

MARCH 17, 2024

Childhood-onset cardiomyopathies represent a rare and poorly understood subset of cardiac disorders. In a recent study published in the European Heart Journal, investigators delved into the demographics and prognosis of pediatric cardiomyopathy patients within the inaugural European Cardiomyopathy Registry. months (IQR: 11.3–15.3),

Cardiomyopathy 119

Cardiomyopathy Pediatrics Article Heart Failure 119

Heart BMJ

FEBRUARY 12, 2025

Cardiomyopathy is a primary determinant of prognosis in FD and typically presents as a heart failure (HF) with a preserved ejection fraction phenotype. 4 Indeed, the use of CPET is recognised in HF guidelines 5 and parameters such as peak oxygen consumption (VO 2peak ) offer a.

Exercise 52

Exercise Preserved Ejection Fraction Cardiomyopathy Heart Failure 52

Med Page Today

NOVEMBER 11, 2024

(MedPage Today) -- A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From proteomic profiling of nearly.

Cardiomyopathy 116

Cardiomyopathy Biomarkers Circulation Research 116

HeartRhythm

FEBRUARY 27, 2025

For the past several decades, research on arrhythmogenic right ventricular (RV) cardiomyopathy has focused on describing the clinical features, genetic underpinnings, and natural history of patients with this condition. Crucial to the field were the initial diagnostic criteria proposed in 1994 and later revised in 2010.

Cardiomyopathy 40

Cardiomyopathy Research 40

Science Daily - Heart Disease

MAY 8, 2024

Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.

Cardiomyopathy 121

Cardiomyopathy Exercise Pediatrics 121

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

Reversible cardiomyopathy with severe heart failure is a rare complication of adrenal crisis. In summary, we described a rare and severe case of adrenal crisis complicated with reversible cardiomyopathy that was caused by isolated ACTH deficiency.

Cardiomyopathy 52

Cardiomyopathy Heart Failure Ultrasound Physiology 52

Med Page Today

MAY 8, 2024

(MedPage Today) -- Updates to national guidelines for the management of hypertrophic cardiomyopathy (HCM) endorse cardiac myosin inhibitor use in certain cases, greenlight more intensive physical activity, and expand treatment options for young.

Cardiomyopathy 111

Cardiomyopathy Exercise 111

Medical Xpress - Cardiology

APRIL 4, 2024

Diabetic cardiomyopathy (DC) is a serious condition characterized by impaired heart function due to diabetes-related metabolic abnormalities. Diabetes is a global health burden. A whopping 536 million people worldwide struggle with diabetes.

Cardiomyopathy 115

Cardiomyopathy Diabetes 115

Med Page Today

JUNE 21, 2024

(MedPage Today) -- As an adjunct to bypass surgery for ischemic cardiomyopathy, a cardiac shockwave therapy aimed at regenerating ischemic myocardium boosted left ventricular ejection fraction (LVEF) and physical function at 1 year in a small sham.

Cardiomyopathy 105

Cardiomyopathy 105

DAIC

JULY 10, 2024

Findings from an observational analysis of ARISE-HF trial participants, newly-published in the Journal of the American College of Cardiology, JACC, shed light on the racial and ethnic disparities in diabetic cardiomyopathy (DbCM), which researchers note may have the potential to inform clinical practice, interventions, and policies.

Cardiomyopathy 113

Cardiomyopathy Diabetes Health Disparities Exercise 113

Open Heart

FEBRUARY 23, 2025

Background Unlike other suggested therapies, myosin inhibitors have been shown to change the course of hypertrophic cardiomyopathy by altering the contractile mechanics of cardiomyocytes. This meta-analysis sought to determine the efficacy of mavacamten and aficamten in hypertrophic cardiomyopathy. years in intervention vs 60.9±10.5

Cardiomyopathy 40

Cardiomyopathy Biomarkers 40

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

Long COVID-19 was associated with a higher risk of thromboembolic disorders [HR 3.12 (1.60, 6.08)], coronary heart disease [HR 1.61 (1.13, 2.31)], stroke [HR 1.71 (1.07,2.72)], arrhythmia [HR 1.60 (1.13, 2.26)], cardiomyopathy [HR 1.71 (1.12, 2.61)], myocarditis [HR 6.11 (4.17,8.94)], hypertension [HR 1.70 (1.56, 1.85)], heart failure [HR 1.72 (1.15,2.59)] (..)

COVID-19 95

COVID-19 Cardiogenic Shock Cardiomyopathy Outcomes 95

Med Page Today

SEPTEMBER 20, 2024

(MedPage Today) -- Better imaging parameters may exist for risk stratification in nonischemic dilated cardiomyopathy (NIDCM), based on a meta-analysis. The presence and extent of late gadolinium enhancement (LGE) on cardiac MRI was a significant.

Cardiomyopathy 98

Cardiomyopathy 98

Cardiovascular Diabetology

NOVEMBER 25, 2024

Diabetic cardiomyopathy (DCM) is a severe cardiovascular complication of diabetes characterized by myocardial hypertrophy, fibrosis, and impaired cardiac function. Fibroblast growth factor 21 (FGF21) has emerg.

Cardiomyopathy 98

Cardiomyopathy Diabetes Cardiac Function 98

Frontiers in Cardiovascular Medicine

FEBRUARY 26, 2025

BackgroundHypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder characterized by asymmetric hypertrophy of the ventricles and the ventricular septum, leading to subsequent left ventricular outflow tract (LVOT) obstruction and diastolic dysfunction.

Pacemaker 52

Pacemaker Cardiomyopathy Ablation Bradycardia 52

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Background Chagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis for cardiomyopathy.

Cardiomyopathy 84

Cardiomyopathy Circulation Biomarkers Laboratory 84

JAMA Cardiology

NOVEMBER 14, 2024

This patient-level meta-analysis of a variety of randomized clinical trials examines the association between mean Kansas City Cardiomyopathy Questionnaire treatment effects and the absolute differences in the proportion of patients experiencing clinically meaningful improvement.

Cardiomyopathy 89

Cardiomyopathy 89

American College of Cardiology

JUNE 3, 2024

The following are key points to remember from a state-of-the-art review on arrhythmia-induced cardiomyopathy (AiCM).

Arrhythmia 75

Arrhythmia Cardiomyopathy Article 75

DAIC

MARCH 26, 2024

Bristol Myers Squibb has announced that it will present data on CAMZYOS (mavacamten) for NYHA class II-III obstructive hypertrophic cardiomyopathy at the American College of Cardiology (ACC) Annual Scientific Session & Expo, ACC.24, 24, taking place April 6-8, 2024 in Atlanta, Georgia. 24 , taking place April 6-8, 2024 in Atlanta, Georgia.

Cardiomyopathy 104

Cardiomyopathy Research Heart Failure Hospital 104

Medical Xpress - Cardiology

JANUARY 14, 2024

Acoramidis yields a significantly better four-step primary hierarchical outcome, including aspects of mortality and morbidity, than placebo for patients with transthyretin amyloid cardiomyopathy, according to a study published in the Jan. 11 issue of the New England Journal of Medicine.

Cardiomyopathy 85

Cardiomyopathy Outcomes 85

HCPLive

APRIL 10, 2024

A trio of experts discuss their perspectives on the recent advancement in pharmacotherapy within the management of hypertrophic cardiomyopathy.

Cardiomyopathy 78

Cardiomyopathy 78

DAIC

MARCH 6, 2024

Food and Drug Administration’s ( FDA ) Breakthrough Device Designation for their ECGvision-TTR Technology for early detection of ATTR-Cardiomyopathy. ECGvision-TTR was developed through state-of-the-art deep learning algorithms and offers the unique ability to analyze 12-lead ECG images to detect signatures of ATTR Cardiomyopathy.

Technology 105

Technology Cardiomyopathy Quality of Life Innovation 105

The New England Journal of Medicine

JANUARY 1, 2025

Among patients with transthyretin amyloidosis with cardiomyopathy, the risk of death from any cause and recurrent cardiovascular events was lower with vutrisiran treatment than with placebo.

Cardiomyopathy 75

Cardiomyopathy 75

JAMA Cardiology

OCTOBER 1, 2024

This randomized clinical trial assesses whether cardioverter-defibrillator implantation is more effective than amiodarone therapy for the primary prevention of all-cause mortality and secondary prevention of sudden cardiac death, hospitalization for heart failure, and use of a pacemaker among patients with chronic Chagas cardiomyopathy.

Defibrillator 77

Defibrillator Cardiomyopathy Sudden Cardiac Death Pacemaker 77

Medical Xpress - Cardiology

JANUARY 8, 2025

Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published in JACC: Basic to Translational Science.

Cardiomyopathy 81

Cardiomyopathy 81

Circulation

DECEMBER 21, 2023

microRNAs translocate into subcellular organelles to modify genes involved in diabetic cardiomyopathy. Malonylation, a posttranslational modification of Ago2, reduced the importing of Ago2 into mitochondria in diabetic cardiomyopathy. BACKGROUND:Diabetes is associated with cardiovascular complications.

Cardiomyopathy 81

Cardiomyopathy Diabetes Circulation 81

Medical Xpress - Cardiology

DECEMBER 3, 2024

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiovascular condition. It is the leading cause of sudden cardiac death in young people and children, with an annual mortality rate of 1%. However, 10% to 20% of these patients have a significantly higher risk of sudden cardiac death.

Sudden Cardiac Death 81

Sudden Cardiac Death Cardiomyopathy 81

JAMA Cardiology

SEPTEMBER 24, 2024

This cohort study evaluates the association of late gadolinium enhancement with sudden cardiac death or relevant associated events among patients younger than 21 years with hypertrophic cardiomyopathy.

Sudden Cardiac Death 78

Sudden Cardiac Death Cardiomyopathy 78

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

An international cardiology working group has published a consensus report on atrial cardiomyopathy in Europace.

Document 67

Document Cardiomyopathy Heart Rhythm 67

HeartRhythm

APRIL 15, 2024

Endocardial electrogram (EGM) characteristics in non-ischemic cardiomyopathy (NICM) have not been explored adequately for prognostication.

Cardiomyopathy 75

Cardiomyopathy Tachycardia 75

Frontiers in Cardiovascular Medicine

JANUARY 3, 2024

Hypertrophic cardiomyopathy is the most common genetic cardiac disorder and is defined by the presence of left ventricular (LV) hypertrophy in the absence of a condition capable of producing such a magnitude of hypertrophy. Over the past decade, guidelines on the screening, diagnostic, and management protocols of pediatric primary (i.e.,

Pediatrics 87

Pediatrics Cardiomyopathy Heart Failure Exercise 87

Dr. Smith's ECG Blog

APRIL 2, 2024

I was there and said, "No, I think this is all due to severe chronic cardiomyopathy and cardiac arrest due to primary ventricular fibrillation, not due to ACS." _ Why did I say that? Patient has an ICD, which is primarily placed in patients with cardiomyopathy. The bedside echo showed dilated cardiomyopathy with relatively thin walls.

Tachycardia 134

Tachycardia Pacemaker Cardiac Arrest Cardiomyopathy 134

Circulation: Genomic and Precision Medicine

FEBRUARY 28, 2024

Dilated cardiomyopathy (DCM) is a common heart muscle disorder of nonischemic etiology associated with heart failure development and the risk of malignant ventricular arrhythmias and sudden cardiac death. Circulation: Genomic and Precision Medicine, Ahead of Print.

Cardiomyopathy 72

Cardiomyopathy Sudden Cardiac Death Article Heart Failure 72

European Journal of Heart Failure

DECEMBER 5, 2024

Oral diuretic intensification was significantly prognostic of mortality amongst patients with transthyretin cardiomyopathy and occurred more often than HF hospitalization.

Outpatient 75

Outpatient Heart Failure Cardiomyopathy Atrial Fibrillation 75

Circulation: Heart Failure

DECEMBER 18, 2023

Recent evidence suggests that loss of PRDM16 expression is associated with cardiomyopathy development in mice, although its role in human cardiomyopathy development is unclear. BACKGROUND:PRDM16 plays a role in myocardial development through TGF-β (transforming growth factor-beta) signaling.

Cardiomyopathy 75

Cardiomyopathy Heart Failure Pediatrics Circulation 75