Trending Articles

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Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries

Medical Xpress - Cardiology

Metal exposure from environmental pollution is associated with increased buildup of calcium in the coronary arteries at a level that is comparable to traditional risk factors like smoking and diabetes, according to a study by Columbia University Mailman School of Public Health.

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A correctable immune niche for epithelial stem cell reprogramming and post-viral lung diseases

Journal of Clinical Investigation - Cardiology

Epithelial barriers are programmed for defense and repair but are also the site of long-term structural remodeling and disease. In general, this paradigm features epithelial stem cells (ESCs) that are called on to regenerate damaged tissues but can also be reprogrammed for detrimental remodeling. Here we identified a Wfdc21-dependent monocyte-derived dendritic cell (moDC) population that functioned as an early sentinel niche for basal ESC reprogramming in mouse models of epithelial injury after

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The gut microbiota in thrombosis

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 17 September 2024; doi:10.1038/s41569-024-01070-6 The gut microbiota has emerged as a risk factor that affects thrombotic phenotypes in several cardiovascular diseases. In this Review, Reinhardt and colleagues discuss the link between the gut microbiota, its metabolites and thromboembolic diseases, and summarize potential therapeutic interventions to modulate the gut microbiota.

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Direct-to-Consumer Drugs: Big Pharma's Digital Health Play

Med Page Today

(MedPage Today) -- More than a quarter of a century ago, the FDA eased regulations to make it easier for pharmaceutical companies to advertise directly to consumers. Today, it is nearly impossible to get through a family sitcom without hearing.

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Babies born to women consuming a high fat, sugary diet at greater risk of cardiovascular disease and diabetes in later life

Science Daily - Heart Disease

Babies born to pregnant women with obesity are more likely to develop heart problems and diabetes as adults due to fetal damage caused by the high-fat, high-energy diet of their mother.

Diet 116
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A transparent AI approach helps provide a more tailored cardiovascular risk assessment

Medical Xpress - Cardiology

Risk calculators are used to evaluate disease risk for millions of patients, making their accuracy crucial. But when national models are adapted for local populations, they often deteriorate, losing accuracy and interpretability.

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Cannabis Cream Safely Reduces Itch in Patients with CKD-Associated Pruritus

HCPLive

A new study found cannabis-containing cream may be effective at alleviating itch in patients with chronic kidney disease (CKD)-associated pruritus with no adverse events.

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Long-term risk of heart failure in adult cancer survivors: a systematic review and meta-analysis

Heart BMJ

Background Cancer survivors are at increased risk of heart failure (HF). While cardiotoxicity is commonly sought at the time of cancer chemotherapy, HF develops as a result of multiple ‘hits’ over time, and there is limited evidence regarding the frequency and causes of HF during survivorship. Objectives This systematic review sought to investigate the relationship between cardiotoxic cancer therapies and HF during survivorship.

Cancer 98
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Biotronik Catheter Gets FDA Approval

DAIC

tim.hodson Mon, 09/16/2024 - 15:15 Sept. 16, 2024 — Biotronik has received U.S. Food and Drug Administration (FDA) labeling approval of its Selectra 3D catheter in conjunction with its Solia S lead for use in left bundle branch area pacing (LBBAP). The two products represent the first and only FDA-approved stylet-driven lead and dedicated delivery catheter system approved for LBBAP.

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Researchers develop new screening tool to help stroke survivors

Medical Xpress - Cardiology

University of Queensland researchers have developed a fast cognitive screening tool that can detect often-missed rehabilitation needs for people who have experienced a stroke.

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3 Cups of Coffee a Day May Reduce the Risk of New-Onset Cardiometabolic Multimorbidity

HCPLive

A new study revealed those who consume a moderate amount of coffee or caffeine had a 48.1% and 40.7% reduced risk for developing cardiometabolic multimorbidity.

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8-Hour Eating Window Improved Glycemic Control, Small Study Shows

Med Page Today

(MedPage Today) -- Eating within an 8-hour window improved glycemic variability in adults at risk for type 2 diabetes, an interim analysis of a randomized crossover study of 15 people showed. Compared with eating over 14+ hours per day, eating.

Diabetes 106
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Addison Gutierrez

Conquering CHD

The Warrior Heart Project Hi my name is Addison Gutierrez! On June 21, 2008 my mom went in for a routine ultrasound. She had low amniotic fluid which meant that she had to have an emergency C section. My dad was a surgery resident at the hospital so he was able to meet her there. I was born at 35 weeks with the lungs of a 28 week old and blue because of my lack of oxygen.

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New guidelines urge regular screenings to prevent peripheral arterial disease complications

Science Daily - Heart Disease

An international group of cardiologists, angiologists and vascular surgeons is urging regular screening to help prevent complications in people with Peripheral Arterial Disease (PAD).

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Chronic kidney disease linked to key cardiovascular risk precursor

Medical Xpress - Cardiology

Overactivation of the sympathetic nervous system is a hallmark sign of chronic kidney disease (CKD) that increases the risk of cardiovascular disease. People with CKD often have impaired sympathetic baroreflex sensitivity—a measure of how well the baroreflex system regulates blood pressure changes. This may contribute to sympathetic nervous system overactivation and related problems, according to researchers from Vitam—Research Center Health Durable in Canada.

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Inadequate Eczema Control Observed in 30% of Patients on Topicals, Systemic Therapies

HCPLive

These poster data highlight that atopic dermatitis treatment may be suboptimal in certain patients, demonstrating the necessity of additional effective therapy options.

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Why Insulin Resistance Is The Biggest Silent Risk Factor For Heart Disease.

Dr. Paddy Barrett

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Everyone sits somewhere on the scale of insulin sensitivity from very insulin sensitive to very insulin resistant at the point of type 2 diabetes. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers.

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Providence Heart Institute planning $42M renovation

Becker's Hospital Review - Cardiology

Renton, Wash.-based Providence is planning a $42 million renovation of the Providence Heart Institute in Spokane, which will increase its patient capacity by 15%, according to a Sept. 17 report from the Spokane Journal of Business.

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Unhealthy behaviors contribute to more coronary artery disease deaths in the poor

Science Daily - Heart Disease

Lower socioeconomic status is associated with higher rates of death from coronary artery disease compared to higher socioeconomic status, and more than half of the disparities can be explained by four unhealthy behaviors, according to a new study.

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Researchers discover new blood group system

Medical Xpress - Cardiology

The discovery of a new blood group, MAL, has solved a 50-year-old mystery. Researchers from NHS Blood and Transplant (Bristol), NHSBT's International Blood Group Reference Laboratory (IBGRL) and the University of Bristol identified the genetic background of the previously known but mysterious AnWj blood group antigen. The findings allow identification and treatment of rare patients lacking this blood group.

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Helping Schools Calculate Respiratory Infection Risk

HCPLive

Wilson details how her team plans to develop risk assessment models to estimate respiratory viral infection risk reductions for interventions in elementary schools.

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Genetic risk-factor overlap between Alzheimer's disease, and all-cause and vascular dementias

Science Daily - Stroke

Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia.

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Over Half of Adults With Uncontrolled Hypertension Unaware of Their Condition

Med Page Today

(MedPage Today) -- More than half of U.S. adults with uncontrolled hypertension are unaware they have hypertension in the first place, according to a recent study in JAMA Network Open. Furthermore, more than two-thirds of those on treatment had.

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C-Arm Radiation Exposure Prevention Tips for Safer Cardiovascular, IR and Hybrid Labs

Cassling

In healthcare, so much of safety and reference materials emphasize how to protect the patient, but there are far fewer resources dedicated toward helping protect you, the provider, over the course of time. While patients may be exposed to radiation only when they come in for an imaging exam or undergo a surgical procedure utilizing a C-arm, the providers who use these systems over the course of years are exposed again and again and again.

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Researchers discover new target for treating heart failure: Protein kinase N

Medical Xpress - Cardiology

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart failure. A group from the Nagoya University Graduate School of Medicine in Japan has found an enzyme protein kinase N (PKN) that regulates heart fibrosis. The enzyme catalyzes the conversion of heart fibroblasts to myofibroblasts, which threatens the integrity of the heart.

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FDA Warns of Liver Injury Risk from Fezolinetant for Hot Flashes

HCPLive

The FDA advises stopping the fezolinetant treatment at the first signs of liver injury to prevent further damage and help restore normal liver function.

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A patient-led Roundtable on late, missed and misdiagnosis of heart disease in women

Heart Sisters

“These cardiac care recommendations are patient-centred and targeted towards addressing women’s specific needs and concerns.

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Metal Exposure Also Linked to More Coronary Artery Calcium

Med Page Today

(MedPage Today) -- Exposure to metals, essential or not, was associated with the progression of subclinical atherosclerosis, according to longitudinal data from a geographically diverse cohort. Study participants with the highest urinary metal.

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Metal exposure can increase cardiovascular disease risk

Science Daily - Heart Disease

Metal exposure from environmental pollution is associated with increased calcium buildup in the coronary arteries at a level comparable to traditional risk factors, according to a new study. The findings support that metals in the body are associated with the progression of plaque buildup in the arteries and potentially provide a new strategy for managing and preventing atherosclerosis.

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Happy with your life? Research links contentment with fewer heart attacks and strokes

Medical Xpress - Cardiology

People who are content with their lives or feel a sense of well-being may be less likely to develop heart disease and/or stroke compared to those with a lower sense of well-being, according to a new analysis published today (Sept. 18) in the Journal of the American Heart Association.

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Low Purine Diet Lower Uric Acid in People With Gout

HCPLive

Patients also experienced a substantial decrease in systolic blood pressure and diastolic blood pressure.

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Risk of clots, stroke from incorrect blood thinner dosing reduced using online dashboard

Science Daily - Stroke

Doctors and pharmacists treating people with blood thinners can reduce the rate of inappropriate dosing -- as well as blood clots and strokes that can result from it -- using an electronic patient management system, a study suggests. Direct oral anticoagulants can be incorrectly prescribed up to 20% of the time.

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PET scan deserts: 7 things to know

Becker's Hospital Review - Cardiology

Approximately 44.2 million people in the U.S. live more than 60 miles away from the nearest cardiac positron emission tomography center, according to a study published Aug. 28 in JACC: Cardiovascular Imaging.

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Breakthrough is a game changer in heart valve technology

Science Daily - Heart Disease

When a patient needs a new heart valve, the current mechanical and tissue replacements each have strengths and weaknesses. Now, a team of researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing -- and life-saving -- for many.

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Study shows estrogen blocker treatment does not increase risk of coronary heart disease in breast cancer patients

Medical Xpress - Cardiology

New evidence shows that extended estrogen suppression treatment using aromatase inhibitors for hormone receptor-positive postmenopausal breast cancer is safe; it does not increase the risk of coronary artery calcification, a sign of active coronary atherosclerosis, as some prior studies had indicated.

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Patients With Arthritis, IBD, Experience High Rates of Long Covid Affecting QoL

HCPLive

Notably, people with fewer vaccine doses were more likely to experience post-acute sequelae of COVID-19.

COVID-19 142
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Survival of men with metastatic hormone-sensitive prostate cancer and adrenal-permissive HSD3B1 inheritance

Journal of Clinical Investigation - Cardiology

BACKGROUND Metastatic hormone-sensitive prostate cancer (mHSPC) is androgen dependent, and its treatment includes androgen deprivation therapy (ADT) with gonadal testosterone suppression. Since 2014, overall survival (OS) has been prolonged with addition of other systemic therapies, such as adrenal androgen synthesis blockers, potent androgen receptor blockers, or docetaxel, to ADT.

Cancer 74