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Increased Use of Radial Access For PCI in the US, Lower Complication Rates | NCDR Study

American College of Cardiology

PCI with radial access site is associated with lower rates of in-hospital mortality, major access site bleeding and other major vascular complications vs. femoral access site and has increased in use in the U.S. over the past decade, overtaking femoral access site.

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Intensive Blood Pressure Control: Do the Benefits and Harms Vary with Baseline Cardiovascular Risk?

NEJM Journal Watch - Cardiology

Although intensive therapy may lead to more adverse events, the benefit-to-harm ratio favors it in patients at all risk levels.

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Prognostic significance of serum galectin-3 in predicting cardiovascular outcomes after percutaneous coronary intervention with drug-eluting stents

Frontiers in Cardiovascular Medicine

BackgroundGalectin-3 is a well-established biomarker on the predictor of cardiovascular events in patients with heart failure. Its pathophysiologic association with inflammation, cell proliferation, and fibrogenesis may implicate serum galectin-3 as a predictor of clinical outcomes in coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents (DES).

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Scientists identify why some heart rhythm drugs heighten risks when sodium levels drop

Medical Xpress - Cardiology

New research explains how low levels of the electrolyte sodium in the blood can disrupt the timing of the heartbeat in patients taking widely used rhythm-control medications such as flecainide, which is commonly prescribed for atrial fibrillation and other fast or irregular heart rhythms.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Myocardial infarction, stroke and arterial stenosis: time to reassess a major misunderstanding

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 18 July 2025; doi:10.1038/s41569-025-01186-3 In this Perspective article, Saba and Libby review the latest evidence highlighting the lack of a correlation between stenosis severity and the risk of atherosclerosis-induced thrombotic complications and question the overreliance on stenosis grading for therapeutic decision-making.

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Cardio‐microcurrent device treatment for heart failure with reduced ejection fraction: Results from the C‐MIC II open‐label randomized controlled trial

European Journal of Heart Failure

Efficacy and Safety of C-MIC Device in Patients with Heart Failure with Reduced Ejection Fraction. 6MWD, 6-min walk distance; CI, confidence interval; KCCQ-OSS, Kansas City Cardiomyopathy Questionnaire overall summary score; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association. Abstract Aims In patients with heart failure, alterations in electrical fields generated within the myocardium have been associated with myocardial oedema which can act as a substrate for left ventri

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Advanced ECG feature extraction and SVM classification for predicting defibrillation success in OHCA

Frontiers in Cardiovascular Medicine

Out-of-hospital cardiac arrest (OHCA) represents a critical challenge for emergency medical services, with the necessity for rapid and accurate prediction of defibrillation outcomes to enhance patient survival. This study leverages a dataset of 251 ECG signals from OHCA patients, consisting of 195 unsuccessful and 56 successful resuscitation attempts as categorized by expert cardiologists.

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Optimal heart health in children cuts risk of chronic diseases in adulthood, review indicates

Medical Xpress - Cardiology

Optimal heart health from birth through adolescence, as measured by a combination of metrics, leads to long-lasting cardiovascular and overall physical, cognitive and mental health, according to the systematic review published in the Journal of the American Heart Association.

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FDA Approvals in Cardiometabolic Health: Highlights from January–July 2025

Cardiometabolic Health Congress

FDA Approvals CMHC (Jan-July 2025) The first half of 2025 has brought an impressive wave of progress in cardiometabolic and renal care, with the U.S. Food and Drug Administration (FDA) granting approvals to several novel therapies and expanded indications. These approvals address a broad spectrum of conditions, including hypertension, diabetes, chronic kidney disease, stroke, and cardiovascular risk reduction—diseases that collectively represent some of the most burdensome and costly challenges

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Heartflow Unveils New Data Showing Impact of Heartflow Plaque Analysis

DAIC

tim.hodson Thu, 07/17/2025 - 14:40 July 17, 2025— Heartflow, Inc. recently announced new data for its AI-enabled Heartflow Plaque Analysis , including final primary endpoint data from the DECIDE Registry. Data from the DECIDE Registry showed Heartflow Plaque Analysis led to medical management change in over half of patients beyond coronary computed tomography angiography (CCTA) alone, regardless of traditional risk factors or CCTA findings.

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Cardiovascular Hospitalizations Burden Following Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundLonger‐term morbidity post septal myectomy (SM) in obstructive hypertrophic cardiomyopathy has not been well characterized at a national level. We aimed to investigate the nonfatal longer‐term post‐SM outcomes from a national all‐payer individual‐level claims.MethodsThe Symphony Health Claims database (2016–2021) was analyzed to identify all adult patients with obstructive hypertrophic cardiomyopathy who underwent SM in the Uni

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Unraveling mitochondrial crosstalk: a new frontier in heart failure pathogenesis

Frontiers in Cardiovascular Medicine

Mitochondria play a central role in energy production and signal transduction in cardiomyocytes. Their dysfunction is a key contributor to the development and progression of heart failure (HF). Beyond energy metabolism, mitochondria regulate calcium homeostasis, autophagy, protein synthesis, lipid metabolism, and gene expression through close interactions with other organelles.

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Clinical trial shows taking blood pressure medication at night improves nocturnal and daytime control

Medical Xpress - Cardiology

Research led by Sichuan University in China has revealed that bedtime antihypertensive medication dosing improves nocturnal blood pressure control over morning dosing in patients with hypertension.

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Cleerly to Present New AI-QCT Research at SCCT 2025

DAIC

tim.hodson Tue, 07/15/2025 - 12:00 July 9, 2025 — Cleerly, a leader in advanced cardiovascular imaging, will be presenting new research at the Society of Cardiovascular Computed Tomography (SCCT) Annual Meeting 2025. The conference will take place July 17-20, 2025, at the Palais des Congrès de Montréal in Montreal, Canada. This annual event brings together leading cardiovascular imaging specialists, researchers, and technology innovators from around the world to share the latest advances in card

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The Single‐Delayed‐Phase Contrast Computed Tomography Before Ablation to Reduce Radiation Exposure Without Compromising Diagnostic Pulmonary Vein Accuracy

Journal of Cardiovascular Electrophysiology

The results of analyzing the early and delayed phases of contrast computed tomography (CCT) images showed that the single-delayed-phase was comparable in evaluating the anatomy and diameter of the pulmonary veins to the single-early-phase. The single-delayed-phase CCT was considered to be effective for evaluation before ablation. ABSTRACT Introduction Early-phase contrast-enhanced CT (CCT) is often used to plan and guide catheter ablation for atrial fibrillation (AF), and delayed-phase images ca

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Prognostic differences between persistent HFrEF and HFrecEF following acute myocardial infarction

Frontiers in Cardiovascular Medicine

BackgroundAcute myocardial infarction (AMI) often leads to heart failure with reduced ejection fraction (HFrEF), with some patients showing recovery of left ventricular ejection fraction (HFrecEF) over time. This study aimed to evaluate the prognostic differences between persistent HFrEF and HFrecEF.MethodsThis prospective cohort study included AMI patients with reduced LVEF ( 40% with an absolute increase of ≥10% from baseline, in accordance with recent consensus definitions.

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AI tool spots hidden heart disease using routine electrocardiogram data

Medical Xpress - Cardiology

With the help of artificial intelligence (AI), an inexpensive test found in many doctors' offices may soon be used to screen for hidden heart disease.

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Increased Use of Radial Access For PCI in the US, Lower Complication Rates | NCDR Study

American College of Cardiology

PCI with radial access site is associated with lower rates of in-hospital mortality, major access site bleeding and other major vascular complications vs. femoral access site and has increased in use in the U.S. over the past decade, overtaking femoral access site.

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The PRECISION Trial

HCPLive

Panelists discuss how the PRECISION trial demonstrated aprocitentan’s efficacy in lowering blood pressure by nearly 15 mm Hg within 4 weeks in resistant hypertension patients, including those with advanced chronic kidney disease, with durable effects and minimal adverse effects except for manageable peripheral edema.

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Metabolite Profiles of Heart Failure, Central Hemodynamic Derangement, and Response to Heart Transplantation

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundHeart failure (HF) is characterized by hemodynamic derangements that are likely to mediate systemic metabolic perturbations but limited data are available. Plasma metabolite profiling provides opportunities for comprehensive investigation of such perturbations. Here, we aimed to characterize plasma profiles that associate with HF and their relationship with central hemodynamics, symptom burden, and response to restoration of ca

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The effects of moxibustion in chronic heart failure patients: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

ObjectiveMoxibustion has been utilized in China for 2,000 years as a safe and straightforward intervention for chronic heart failure (CHF). Numerous articles indicate that moxibustion enhances quality of life and certain heart failure indicators in CHF patients; however, there is a deficiency of high-quality, evidence-based studies with large sample sizes.

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Treating the Broken Heart: Role of Stellate Ganglion Block in Takotsubo Syndrome

Journal of Cardiovascular Pharmacology

Takotsubo syndrome (TTS) is an acute stress-induced cardiomyopathy characterized by transient left ventricular dysfunction, often mimicking acute myocardial infarction but without obstructive coronary artery disease. While typically reversible, TTS can be complicated by serious adverse events, including life-threatening ventricular arrhythmias (VAs).

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Increased Use of Radial Access For PCI in the US, Lower Complication Rates | NCDR Study

American College of Cardiology

PCI with radial access site is associated with lower rates of in-hospital mortality, major access site bleeding and other major vascular complications vs. femoral access site and has increased in use in the U.S. over the past decade, overtaking femoral access site.

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Access to digital health technologies: personalized framework and global perspectives

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 16 July 2025; doi:10.1038/s41569-025-01184-5 In this Review, Narayan and colleagues discuss global disparities in access to digital health technologies, with a focus on cardiovascular medicine. The authors summarize the factors that affect access at various levels of society and present solutions that target each of these levels, culminating in a personalized framework to improve access to digital health technologies.

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New drug offers hope of cure for hormone-driven high blood pressure

Medical Xpress - Cardiology

An international team of researchers led by Professor Morris Brown FRS at Queen Mary University of London found that Baxdrostat, a drug belonging to a new class of aldosterone synthase inhibitors, led to an average fall in blood pressure of 25 mmHg. This is two to three times the reduction typically achieved by a single antihypertensive drug.

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Research status of triglyceride glucose-body mass index (TyG-BMI index)

Frontiers in Cardiovascular Medicine

Insulin resistance (IR) represents a pivotal metabolic risk factor, with metabolic abnormalities intricately linked to increased predisposition to cardiovascular, digestive, and immune system disorders. While the triglyceride glucose (TyG) index is widely recognized as a simple and specific surrogate marker for IR, the triglyceride glucose body mass index (TyG-BMI), incorporating obesity metrics, has emerged as a more robust predictor of IR.

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Physical findings on hands in cardiovascular disease

All About Cardiovascular System and Disorders

Examination of hands may give a lot of important findings in cardiovascular disease. Cold clammy hands in cardiogenic shock is well known. Body’s protective mechanisms reduce blood flow to extremities and divert blood flow to vital organs like brain and heart. That makes the skin cool. ‘Clammy’ indicates that the skin is moist to touch like a clam!

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Increased Use of Radial Access For PCI in the US, Lower Complication Rates | NCDR Study

American College of Cardiology

PCI with radial access site is associated with lower rates of in-hospital mortality, major access site bleeding and other major vascular complications vs. femoral access site and has increased in use in the U.S. over the past decade, overtaking femoral access site.

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Cardiac Rehabilitation: An Essential Step in Your Recovery Journey

AMS Cardiology

After a heart attack or procedure, it’s normal to have questions about what comes next. You need appropriate support and education in order to return to your previous level of strength. That support comes from cardiac rehab. AMS Cardiology builds a clear, structured program for each individual, including exercise, nutrition, education and emotional support.

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Association of Atherogenic Index of Plasma With Stroke Risk in a Population With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0 to 3: The First Evidence From the China Health and Retirement Longitudinal Study

Journal of the American Heart Association

Journal of the American Heart Association, Ahead of Print. BackgroundThe atherogenic index of plasma (AIP) is a marker of lipids and atherosclerosis. However, its associations with stroke risk in a population with cardiovascular‐kidney‐metabolic (CKM) syndrome stages 0 to 3 remain unclear.MethodsThe data for this study were obtained from CHARLS (China Health and Retirement Longitudinal Study).

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Emerging therapy targets to modulate microbiome-mediated effects evident in cardiovascular disease

Frontiers in Cardiovascular Medicine

The human gut microbiota influences host metabolism, immune responses, and inflammation, with microbial dysbiosis linked to metabolic disorders and increased cardiovascular disease risk. Notably, metabolites such as short-chain fatty acids, trimethylamine N-oxide, and bile acids, which are influenced by the microbiome and its functional composition, have been implicated in vascular health, immune modulation, and atherosclerosis.

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Categories of Biomarkers according to FDA-NIH BEST

All About Cardiovascular System and Disorders

BEST (Biomarkers, EndpointS, and other Tools) Resource is a FDA-NIH Joint Leadership Council initiative. The various categories of biomarkers considered include: Diagnostic Biomarker Monitoring Biomarker Multicomponent Biomarker Predictive Biomarker Prognostic Biomarker Response Biomarker Safety Biomarker Susceptibility/Risk Biomarker A discussion of some of those relevant to cardiology with examples follows.

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Increased Use of Radial Access For PCI in the US, Lower Complication Rates | NCDR Study

American College of Cardiology

PCI with radial access site is associated with lower rates of in-hospital mortality, major access site bleeding and other major vascular complications vs. femoral access site and has increased in use in the U.S. over the past decade, overtaking femoral access site.

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Incidence and Outcome of Cardiac Arrest Over Time

JAMA Cardiology

This cohort study investigates whether the incidence or outcome of out-of-hospital cardiac arrest (OHCA) is changing over time overall or among important demographic or clinical groups.

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Effects of high-intensity interval training on cardiopulmonary function and quality of life in post-PCI or CABG patients with coronary heart disease: a meta-analysis

Journal of Cardiothoracic Surgery

High-intensity interval training (HIIT) has emerged as a potential cardiac rehabilitation strategy for coronary heart disease (CHD) post-surgery, but its efficacy compared to moderate-intensity continuous trai.

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Key inflammatory players for infarcted mass and cardiac remodeling after acute myocardial infarction

Frontiers in Cardiovascular Medicine

Atherosclerosis has been defined as an inflammatory disease. As observed during acute infections, excess inflammatory activity is associated with disease severity and mortality. After myocardial infarction, several waves of inflammatory cells play a crucial role in infarct size and cardiac remodeling. In the short and long term, subtypes of inflammatory cells and cytokines released orchestrate the healing and stability of coronary disease.