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Light-activated ink developed to remotely control cardiac tissue to repair the heart

Medical Xpress - Cardiology

Researchers from Mass General Brigham and collaborating institutions have developed a non-invasive approach to manipulate cardiac tissue activity by using light to stimulate an innovative ink incorporated into bioprinted tissue. Their goal is to develop a technique that can be used to repair the heart. Their findings in preclinical models, published in Science Advances, show the transformative potential of non-invasive therapeutic methods to control electrically active tissues.

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The relationship between cannabis and cardiovascular disease: clearing the haze

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 23 January 2025; doi:10.1038/s41569-025-01121-6 In this Review, Wu and colleagues discuss the evolution in cannabis regulation, the endocannabinoid system and cannabinoid receptors, the influence of cannabis on cardiovascular risk factors, and the effects of traditional and synthetic cannabinoids on cardiovascular health and disease.

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Fatty muscles raise the risk of serious heart disease regardless of overall body weight

Science Daily - Heart Disease

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to new research. This 'intermuscular' fat is highly prized in beef steaks for cooking. However, little is known about this type of body fat in humans, and its impact on health.

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GLP-1 Agents' Risks and Benefits Broader Than Previously Thought

Med Page Today

(MedPage Today) -- An observational study of 175 health outcomes using Veterans Affairs (VA) data for nearly 2 million individuals uncovered new insights about possible risks and benefits of GLP-1 receptor agonists. Over a median of 3.68 years.

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High Pollen Exposure Linked to Increased Chronic Respiratory Mortality

HCPLive

A new study found high concentrations of pollen from 3 species classesragweed, deciduous trees, and grassare linked to increased chronic respiratory mortality.

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Anti-clotting drug significantly reduces bleeding events in patients with atrial fibrillation, clinical trial shows

Medical Xpress - Cardiology

Patients with atrial fibrillation are typically prescribed an anticoagulant, or blood thinner, to reduce the risk of stroke, but many may discontinue them or never receive a prescription due to concerns of increased risk of bleeding complications.

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Should we wait for troponin when the ECG does not show "diagnostic" ST Elevation?

Dr. Smith's ECG Blog

Written by Willy Frick A 52 year old man with hypertension, dyslipidemia, and seropositive rheumatoid arthritis (a risk factor for CAD) presented with acute substernal chest pressure with diaphoresis which woke him from sleep just after midnight. He said it felt like "someone ripped [his] heart out." Ominous. While walking into the ED, the patient had an episode of "dizziness" causing him to fall onto his stomach.

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ECG Blog #466 — Do You See What I See?

Ken Grauer, MD

I was sent the ECG in Figure-1 without clinical information. I interpreted the rhythm as AFib ( A trial F ibrillation ). QUESTION: Do you see anything else? Figure-1: The initial ECG in today's case. Take another LOOK. To facilitate description I've numbered the beats in Figure-2. Figure-2: I've numbered the beats from Figure-1. Confession: I initially looked at this tracing too quickly.

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Mindfulness Reduces Cravings in OUD, No Impact on Abstinence

HCPLive

Mindfulness eased opioid cravings in OUD patients on buprenorphine but showed no added benefit over recovery support for abstinence, substance use, or anxiety.

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More Thyroid Cancers Found After Starting GLP-1s: Researchers Think They Know Why

Med Page Today

(MedPage Today) -- More thyroid cancers were detected soon after starting a GLP-1 receptor agonist than other diabetes drugs, a secondary analysis of a target trial emulation of a comparative effectiveness study found. Of over 350,000 adults with.

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Researchers make breakthrough in bioprinting functional human heart tissue

Science Daily - Heart Disease

Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The breakthrough science focused on replicating heart tissues, bringing research closer to generating functional, bioprinted organs, which would have broad applications in disease modelling, drug screening and regenerative medicine.

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Electrocoagulation-free strategy in minimally invasive direct coronary artery bypass with hybrid revascularisation – a case report

Journal of Cardiothoracic Surgery

Hybrid coronary revascularisation benefits patients with multivessel disease, as it amalgamates the minimally invasive direct coronary artery bypass (MIDCAB) procedure and percutaneous coronary intervention (P.

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Ohio children's hospitals partner on cardiac surgery

Becker's Hospital Review - Cardiology

"Cincinnati Children's and Akron Children's partner for comprehensive cardiovascular care, expanding treatment options for children with complex heart condition

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HDL Antioxidant Function Diminished in Patients with HFpEF, Study Finds

HCPLive

Increases in oxidized HDL levels were linked to HFpEF in new analyses, suggesting reduced antioxidant HDL function is present in this patient population.

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Drug shows promise in preventing heart failure post-heart attack in mice

Medical Xpress - Cardiology

A specially designed drug prevented laboratory mice from developing heart failure after heart attacks, according to new research from Cedars-Sinai. This discovery could lead to new treatments to prevent heart failure, a serious cardiac condition that develops in up to 30% of heart attack survivors within one year.

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New Study Finds Mechanical Valves Offer Superior Long-Term Survival for Aortic Valve Replacement Patients Aged 60 and Younger

Society of Thoracic Surgeons - Congenital

Press Release New Study Finds Mechanical Valves Offer Superior Long-Term Survival for Aortic Valve Replacement Patients Aged 60 and Younger January 25, 2025 KCummings Sat, 01/25/2025 - 13:33 LOS ANGELESJanuary 25, 2025A late-breaking study presented today at the 2025 Society of Thoracic Surgeons (STS) Annual Meeting reveals that mechanical aortic valve replacements (AVRs) provide significant long-term survival benefits for patients aged 60 and younger compared to bioprosthetic valves.

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Interventions for adult congenital heart disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 20 January 2025; doi:10.1038/s41569-025-01118-1 The past 20 years have witnessed remarkable progress in the evolution of transcatheter procedures for the treatment of adult patients with congenital heart disease. In this Review, Rods-Cabau and colleagues provide a comprehensive overview of the available transcatheter interventions for these patients, focusing on their current indications and associated outcomes.

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Study shows anti-clotting drug reduced bleeding events in patients with atrial fibrillation

Science Daily - Heart Disease

Researchers evaluated a drug that represents a new class of anticoagulants known as Factor XI inhibitors for treating patients with atrial fibrillation as part of the AZALEA-TIMI 71 Study. The trial was stopped early by the recommendation of the Data Monitoring Committee due to an overwhelming reduction in bleeding compared to standard-of-care treatment.

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JAKi Treatment for Psoriatic Arthritis Not Associated With Increased CVD, VTE, Cancer Risk

HCPLive

Cancer risk was examined for breast, colorectal, lung, and prostate cancer.

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Marginalized patients more likely to still take daily aspirin despite risks

Medical Xpress - Cardiology

The prevalence of daily low-dose aspirin use fell significantly after the American College of Cardiology and the American Heart Association narrowed recommendations in 2019. However, new research published Jan. 22 in JAMA shows that message has not reached all population segments equally, leaving some groups at greater risk of adverse effects like gastrointestinal bleeding and intracerebral hemorrhage.

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Microplastics in Water; New NCD for CardioMEMS; Valve Surgery Amid Los Angeles Fires

Med Page Today

(MedPage Today) -- A study showed that microplastics -- small enough to pass into human blood and organs -- were found in tap and bottled water in France. (PLOS Water) Artificial intelligence (AI) enabled non-experts to produce high-quality.

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Acute chest pain with LBBB and obvious OMI, worsening on serial ECGs, but repeatedly missed by physicians and Marquette 12SL

Dr. Smith's ECG Blog

This was written by Hans Helseth. He just graduated from college. He has no medical training, but he has read this blog for years. He is an ECG tech who hopes to go to medical school. He has never been poisoned by the STEMI/NSTEMI paradigm because he has never been to medical school. Lucky Hans. You don't need to have medical training to recognize OMI on the ECG.

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While most Americans use a device to monitor their heart, few share that data with their doctor

Science Daily - Heart Disease

A new national survey found that while many Americans use a device to monitor their heart, few share that data with their doctor.

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Air Pollution, Climate Change Exacerbate COPD, Asthma

HCPLive

Meteorological conditions effect on exacerbations were likely mediated by particulate matter.

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Stroke procedural numbers are an unreliable predictor of patient outcomes, finds study

Medical Xpress - Cardiology

According to new research from the University of Missouri School of Medicine, the number of mechanical thrombectomies performed at hospitals is not an accurate indicator of patient outcomes.

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Injectable Anticoagulant Substantially Cuts Bleeding Risk in Afib

Med Page Today

(MedPage Today) -- For people with atrial fibrillation (Afib), investigational abelacimab proved to be a potent dual factor XI/XIa inhibitor with much lower safety risks compared with a direct oral anticoagulant (DOAC), according to the AZALEA.

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Driving Restrictions and Incapacitation Vulnerability Evaluation After ST-Segment–Elevation Myocardial Infarction: DRIVE-STEMI Study

Circulation

Circulation, Volume 151, Issue 3 , Page 282-284, January 21, 2025.

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Yellowish Nodules on a Man Consuming a Carnivore Diet

JAMA Cardiology

This case report describes a diagnosis of xanthelasma in a man in his 40s who adopted a carnivore diet 8 months before presentation.

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Dupilumab Demonstrates Efficacy for Severe Uncontrolled CRSwNP Up Until 1 Year

HCPLive

Dupilumab improves severe CRSwNP symptoms, such as nasal obstruction and quality of life, showing significant efficacy within 6-12 months.

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Intraosseous or Intravenous Vascular Access for Out-of-Hospital Cardiac Arrest

The New England Journal of Medicine

This randomized trial showed no significant difference in return of spontaneous circulation between initial intraosseous and intravenous vascular access in adults with out-of-hospital cardiac arrest.

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Good Response to Obesity Treatment in Childhood Improved Outcomes Down the Line

Med Page Today

(MedPage Today) -- Beneficial pediatric obesity treatment response was associated with a reduced risk of obesity-related events in young adults, a nationwide prospective cohort study in Sweden showed. Compared with poor response, good response.

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Negative vs. positive experiences: what you remember may depend on emotions

Heart Sisters

If asked about a negative experience like the exact moment you were diagnosed with heart disease, would you be able to accurately recall that moment?

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Supine Blood Pressure and Risk of Cardiovascular Disease and Mortality

JAMA Cardiology

This cohort study investigates the association of supine hypertension with cardiovascular disease and mortality in middle-aged adults.

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ONS-5010 for Wet AMD Secures Noninferiority in NORSE EIGHT Trial

HCPLive

With a completed 12-week analysis, Outlook Therapeutics plans to resubmit the Biologics License Application for ONS-5010 in the first quarter of 2025.

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Symptoms of viral influenza, COVID-19, norovirus, and RSV can be signs of potential heart complications, warn experts

Medical Xpress - Cardiology

With a recent surge in influenza, COVID-19, norovirus, respiratory syncytial virus (RSV), and other respiratory viruses, it's critical to pay close attention to your heart and symptomsespecially if you have heart disease or the risk factors for it. That's the message from experts at Mount Sinai Fuster Heart Hospital during American Heart Month.

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Physiology Friday #254: Fueling for Performance and Health: Lessons from a Recent Low-Carb vs. High-Carb Study in Athletes

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. You can find more products I’m affiliated with on my website. Physiologically Speaking is a reader-supported publication.

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No Clear Winner in SGLT2 Showdown for Cardiovascular Disease

Med Page Today

(MedPage Today) -- Individual SGLT2 inhibitors showed roughly comparable cardiovascular effectiveness and safety in an observational study of real-world claims data. Compared with people who had type 2 diabetes treated with empagliflozin (Jardiance.