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ECG Blog #451 — Premature Closure.

Ken Grauer, MD

I was sent the ECG shown in Figure-1 — told only that the patient was a middle-aged man with septicemia. QUESTIONS: Is this rhythm too fast to be sinus tachycardia? Are flutter waves hidden within the QRS and T waves? Are we seeing the retrograde P waves of AVNRT? Is this ATach ( A trial T achycardia )? Figure-1: The initial ECG in today's case. MY Thoughts on Today’s CASE: In my opinion — none of the above answers are optimal to describe the rhythm in Figure-1.

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COVID-19 infection appeared to increase risk of heart attack & stroke up to 3 years later

American Heart News - Heart News

Research Highlights: An analysis of UK Biobank health data that included adults who had mild to severe COVID-19 before vaccines were available found an increased risk of heart attack, stroke and death among those adults during the nearly three-year.

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History of COVID-19 found to double long-term risk of heart attack, stroke and death

Medical Xpress - Cardiology

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

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Certain Arm Positions Can Lead to Inaccurate Blood Pressure Readings

Med Page Today

(MedPage Today) -- Certain arm positions -- supported on a lap or hanging by the side of the body -- led to significant overestimation of blood pressure readings compared with standardized positioning, a randomized trial in JAMA Internal Medicine.

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First Melanoma History is Risk Factor for Subsequent Diagnoses Regardless of Race

HCPLive

This analysis indicates that patients with a history of a first melanoma are at risk for subsequent development of melanoma regardless of their race or their ethnicity.

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Arm position effect on blood pressure readings: 5 things to know

Becker's Hospital Review - Cardiology

Insufficient arm support can lead to an overestimated blood pressure reading of almost 7mmHG and a potential misdiagnosis of hypertension, according to a study published Oct. 7 in JAMA Internal Medicine.

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Heart failure, atrial fibrillation & coronary heart disease linked to cognitive impairment

American Heart News - Heart News

Statement Highlights: Previous studies have found that 14-81% of patients with heart failure experience some degree of cognitive impairment affecting language, memory or executive function. Evidence also indicates that people with atrial fibrillation.

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Loneliness Tied to Alzheimer's and Dementia Risk

Med Page Today

(MedPage Today) -- Loneliness increased the risk for all-cause dementia, a meta-analysis that included more than 600,000 people showed. Feeling lonely was tied to a 31% higher risk of overall dementia (HR 1.306, 95% CI 1.197-1.426), according.

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Nanoscope Signals BLA Submission for MCO-010 for Retinitis Pigmentosa

HCPLive

Based on the regulatory feedback provided by the FDA, Nanoscope announced plans to initiate Biologics License Application submission in Q1 2025.

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How terrible can it be to fail to recognize OMI? To whom is OMI Obvious or Not Obvious?

Dr. Smith's ECG Blog

This was sent to me by a reader who wishes to remain anonymous. A lady in her 60s came to the ER with chest discomfort and shortness of breath. She had a history of previous anterior MI treated by primary PCI to the proximal LAD. The first EKG is from 2:30 PM on the day of presentation to the ER. Smith : To me this is a blatantly obvious acute anterior OMI.

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Are We Too Obsessed with Protein?

Physiologically Speaking

Protein is everywhere. High-protein cereal. Protein-packed frozen meals. There’s even protein water. The deluge of protein-centric products is the result of one thing: we’re convinced that we don’t get enough of it. Or at least that’s what everyone wants you to think. Has the fixation on protein come at a cost? Maybe. One thing I’ve noticed is that the term “protein” is now equated with “healthy.” This couldn’t be further from the truth

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Researchers succeed in creating two interconnected vascular networks

Medical Xpress - Cardiology

Researchers from the Faculty of Medicine and Health Technology (MET) at Tampere University have successfully created a cell culture platform that allows two cultivated vascular networks to interconnect. The blood vessels in these networks are equivalent to human capillaries in size and structure, facilitating the study of human capillary networks in a laboratory setting.

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Checkpoint Inhibitors for Lung Cancer Linked to Pulmonary Embolism

Med Page Today

(MedPage Today) -- BOSTON -- Patients with metastatic lung cancer who were treated with immune checkpoint inhibitors (ICIs) had higher odds of developing a pulmonary embolism, according to a retrospective cohort study. Among propensity-matched.

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Short-Term Surge in Air Pollution May Trigger Schizophrenia Episodes

HCPLive

A short-term rise in air pollution levels between neighboring days was significantly linked to an increased risk of schizophrenia hospitalizations in China.

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If you were this patient, would you prefer to be managed with the Queen of Hearts?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his early sixties with no significant medical history (including a "negative cardiac workup a few years ago" for unclear indication) called 911 for acute chest pain constantly for the past 5 hours. EMS arrived and recorded vital signs within normal limits and the following ECG during active pain: EMS1 @ 0157: What do you think?

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COVID-19 infection appeared to increase risk of heart attack and stroke up to 3 years later

Science Daily - Heart Disease

An analysis of data in the UK Biobank has found that COVID-19 infection may increase the risk of heart attack, stroke and death from any cause for up to three years for people with and without cardiovascular disease, according to new research.

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Commonly used arm positions can substantially overestimate blood pressure readings, study finds

Medical Xpress - Cardiology

A study led by Johns Hopkins Medicine researchers concludes that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.

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The heart health, dementia link: 7 things to know

Becker's Hospital Review - Cardiology

Addressing heart health earlier in life may affect and even deter dementia risk later in life, according to research published by The American Heart Association Oct. 10 in Stroke.

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Jonathan Meyer, MD: Cognitive Gains, Dopamine-Free Schizophrenia Treatment with Xanomeline Trospium Chloride

HCPLive

Xanomeline trospium chloride offers a new pathway in schizophrenia treatment, improving cognitive symptoms without D2 receptor-related side effects like tardive dyskinesia.

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An elderly male with acute altered mental status and huge ST Elevation

Dr. Smith's ECG Blog

Written by Bobby Nicholson What do you think of this “STEMI”? A man in his 90s with a history of HTN, CKD, COPD, and OSA presented to the emergency department after being found unresponsive at home. With EMS, patient had a GCS of 3 and was saturating 60% on room air. He improved to 100% with the addition of non-rebreather, however remained altered and was intubated by EMS with ketamine and succinylcholine.

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Highest Paid Medical Specialties in 2024

Med Page Today

(MedPage Today) -- While it's true that becoming a doctor means a guaranteed six-figure salary, these salaries vary dramatically between specialties. The good news is in 2024, the Physician Compensation Report from Doximity listed 12 medical.

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Commonly used arm positions can substantially overestimate blood pressure readings

Science Daily - Heart Disease

Researchers conclude that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.

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Do patients have a “happiness set point?”

Heart Sisters

The best predictor of how happy you'll be several months after a major life event (positive or negative) might be how happy you were before it happened.

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FASCINATE-2: Denifanstat Improves Disease Activity, MASH Resolution, Fibrosis

HCPLive

New phase 2b data highlight denifanstat’s impact on histological features of MASH, meeting both fibrosis improvement and MASH resolution primary endpoints.

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La insuficiencia cardíaca, la fibrilación auricular y la enfermedad coronaria están relacionadas con el deterioro cognitivo

American Heart News - Heart News

Aspectos destacados de la declaración: En estudios anteriores se ha descubierto que entre el 14 y el 81% de los pacientes con insuficiencia cardíaca presentan algún grado de deterioro cognitivo que afecta el lenguaje, la memoria o la función.

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One Way to Spot Early Cognitive Decline? Medicare Wellness Visits

Med Page Today

(MedPage Today) -- A Medicare annual wellness visit (AWV) was associated with greater recognition of mild cognitive impairment in older adults, a population-based cohort study in Texas showed. Compared with those who didn't have an annual visit.

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Common consumer product chemicals now tied to cardiac electrical changes

Science Daily - Heart Disease

Some environmental phenols are known to have cardiac toxicities. Now, a new study is revealing their adverse impact on the heart's electrical properties.

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Cardiac Contributions to Brain Health: A Scientific Statement From the American Heart Association

Stroke Journal

Stroke, Ahead of Print. The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Thus, achieving optimal brain health has been identified as a public health priority and a major challenge. Cardiovascular diseases are the leading cause of death and disability in the United States and around the world.

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CGRP Monoclonal Antibodies Not More Effective Than Topiramate or Botox for Treating Migraine

HCPLive

A study finds CGRP monoclonal antibodies are not clinically superior to topiramate or Botox in treating chronic migraines, raising cost-effectiveness concerns.

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Early Treatment of Atrial Fibrillation for Stroke Prevention Trial

American College of Cardiology

The goal of the EAST-AFNET 4 trial was to compare a rhythm-control strategy vs. usual care (rate control in the majority of cases) among patients with a recent diagnosis of atrial fibrillation (AF).

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SGLT2 Inhibitors Tied to Better Outcomes in Pulmonary Arterial Hypertension

Med Page Today

(MedPage Today) -- BOSTON -- Sodium-glucose cotransporter-2 (SGLT2) inhibitors were linked to long-term reductions in mortality risk among patients with pulmonary arterial hypertension (PAH), according to an observational cohort study. At 1.

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Having a sweet tooth is linked to higher risk of depression, diabetes, and stroke, study finds

Science Daily - Heart Disease

People with a preference for sweets are at a higher risk of developing depression, diabetes, and suffering a stroke, according to new research.

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UMass hospital cuts heart failure readmissions in half

Becker's Hospital Review - Cardiology

Southbridge, Mass.-based UMass Memorial Health-Harrington Hospital reduced the all-cause 30-day readmission for heart failure patients by 50% as part of a remote patient monitoring program with digital health company Brook Health.

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Age at Onset Predicts Longevity in Long-Term Care of Schizophrenia

HCPLive

Factors, including older age at onset and longer length of stay, may predict longevity for schizophrenia in psychiatric long-term care settings.

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Trial finds metabolic risk contributes to diabetes onset in people with HIV

Medical Xpress - Cardiology

For people with HIV (PWH) with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk, metabolic risk factors contribute to new-onset diabetes mellitus (DM) among those treated with pitavastatin or placebo, according to a study published online Oct. 8 in the Annals of Internal Medicine.

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Cardiac Surgery-Associated AKI Lower With Extracorporeal Blood Purification

Med Page Today

(MedPage Today) -- A nonselective extracorporeal blood purification (EBP) device connected to the cardiopulmonary bypass circuit during surgery reduced the risk of cardiac surgery-associated acute kidney injury (CSA-AKI), a randomized trial found.

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Research advances infusion designed to clean arteries

Science Daily - Heart Disease

Inflammation of the arteries is a primary precursor and driver of cardiovascular disease -- the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries. Advanced treatments are needed to target this inflammation in patients. Researchers have tested a new nanoparticle nanotherapy infusion that precisely targets inflammation and activates the immune system to help clear out arterial plaque.