Med Page Today
DECEMBER 5, 2024
(MedPage Today) -- Older individuals with apparent skeletal muscle mass loss were at greater risk of developing dementia, researchers found. People with low temporalis muscle mass -- a set of jawbone muscles linked to changes in whole-body skeletal.
Dr. Malcolm Kendrick
DECEMBER 5, 2024
And so, we reach the final end to the court case. You may think it all finished months ago, not so. The final, final act is when we have the reading of the Statement in Open Court (SIOC). This took place Thursday the 5 th of December 2024. Which is five years and nine months after the articles in the Mail on Sunday were published. I could not talk or write about the SIOC before it happened, or the Judge would be most upset and angry.
Ken Grauer, MD
NOVEMBER 30, 2024
I was sent this tracing — and told that providers thought that the rhythm was 3rd-degree ( ie, complete ) AV block. Do YOU agree? Figure-1: The initial ECG in today’s case. NOTE: The tracing in Figure-1 is an 8-lead rhythm strip ( and not a complete 12-lead ECG ). This offers the advantage of providing 8 leads with simultaneously-recorded viewpoints of the same 7 beats that we see in this tracing.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Epidermal stem cells control homeostasis and regeneration of skin and hair. In the hair follicle (HF) bulge of mammals, populations of slow-cycling stem cells regenerate the HF during cyclical rounds of anagen (growth), catagen (regression), and telogen (quiescence). Multipotent epidermal cells are also present in the HF above the bulge area, contributing to the formation and maintenance of sebaceous gland and upper and middle portions of the HF.
Dr. Smith's ECG Blog
NOVEMBER 30, 2024
Written by Jesse McLaren, with edits from Meyers Four patients presented with chest pain or shortness of breath, and ECGs labeled ‘inferior STEMI’. Using principles of hyperacute T waves, do any have inferior occlusion MI? Patient 1 : 60 year old with shortness of breath Patient 2 : 40 year old with chest pain Patient 3 : 65 year old with chest pain Patient 4 : 55 year old, prior inferior MI, with chest pain See this recent post on the new and evolving science of hyperacute T waves, including 1.
Medical Xpress - Cardiology
NOVEMBER 29, 2024
Using a gene-screening method they created, Stanford Medicine researchers may have discovered why an effective chemotherapy damages heart cells—and they have identified a drug that could keep the heart cells beating.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Usher syndrome type 1F (USH1F), resulting from mutations in the protocadherin-15 (PCDH15) gene, is characterized by congenital lack of hearing and balance, and progressive blindness in the form of retinitis pigmentosa. In this study, we explore an approach for USH1F gene therapy, exceeding the single AAV packaging limit by employing a dual–adeno-associated virus (dual-AAV) strategy to deliver the full-length PCDH15 coding sequence.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Science Daily - Heart Disease
DECEMBER 3, 2024
An average of four minutes of incidental vigorous physical activity a day could almost halve the risk of major cardiovascular events, such as heart attacks, for middle-aged women who do not engage in structured exercise, according to new research.
Becker's Hospital Review - Cardiology
DECEMBER 2, 2024
Salt Lake City-based Intermountain Health's St. Mary's Regional Hospital in Grand Junction, Colo., has become the first community hospital in the nation to receive vascular verification from the American College of Surgeons and the Society for Vascular Surgery.
HCPLive
DECEMBER 5, 2024
Perspective from neurologists on the current and future applications for artificial intelligence across a bevy of neurologic conditions.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Microglia are recognized as the main cells in the central nervous system responsible for phagocytosis. The current study demonstrates that in prion disease, microglia effectively phagocytose prions or PrPSc during early preclinical stages. However, a critical shift occurred in microglial activity during the late preclinical stage, transitioning from PrPSc uptake to establishing extensive neuron-microglia body-to-body cell contacts.
Med Page Today
DECEMBER 3, 2024
(MedPage Today) -- Traces of nine essential metals and non-essential metals in urine were linked with lower cognitive performance and the risk of future dementia, a large prospective study showed. The study assessed concentrations of the essential.
Dr. Smith's ECG Blog
DECEMBER 3, 2024
This was written by one of our fine residents, who will soon be an EMS fellow: Michael Perlmutter Case A mid-50s male came to the ED with a burning sensation that was acutely worse while at home. He had recently returned from overseas travel where these symptoms had been intermittently bothersome over the preceding weeks and had been attributed to heartburn.
Science Daily - Heart Disease
DECEMBER 2, 2024
Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study. According to the researchers, these risk reductions are likely driven by the replacement of red and processed meats with plant proteins. The researchers also observed that a combination of consuming more plant protein and higher protein intake overall provided the most heart health benefits.
HCPLive
NOVEMBER 29, 2024
A study found patients with schizophrenia exhibiting violence, vs. those who don’t, have less gray matter volume in the frontal lobe and greater thyroid-stimulating hormone levels.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Type 1 diabetes (T1D) develops spontaneously despite functional antigen presentation machinery in the thymus and a perceptible central tolerance process. We found that intrathymic enrichment with IL-4 fine tunes signaling through the IL-4/IL-13 heteroreceptor (HR) in early thymic progenitors (ETPs), augments negative selection of self-reactive T cells, sustains a diverse T cell repertoire devoid of clones expressing disease-associated T cell receptor (TCR) genes, and protects the nonobese diabet
Med Page Today
DECEMBER 5, 2024
(MedPage Today) -- Use of empagliflozin (Jardiance) was not linked to a lower risk of incident nonproliferative diabetic retinopathy compared with dipeptidyl peptidase-4 (DPP-4) inhibitors among patients with type 2 diabetes, but the SGLT2 inhibitor.
ECG Cases
DECEMBER 3, 2024
In this month's ECG Cases Jesse McLaren takes us through 6 cases highlighting important mirror concepts in ECG interpretation including: which leads are reciprocal to each other, how to identify which is the main ST/T change and which is the mirror, reciprocal changes highlighting subtle inferior, lateral and posterior OMI, ST elevation in aVR as a mirror to widespread ST depression and more.
Science Daily - Heart Disease
DECEMBER 4, 2024
Earlier research showed that primary care clinicians using AI-ECG tools identified more unknown cases of a weak heart pump, also called low ejection fraction, than without AI. New study findings suggest that this type of screening is also cost-effective in the long term, especially in outpatient settings.
HCPLive
DECEMBER 4, 2024
Data from SURMOUNT-5, a head-to-head trial, demonstrate tirzepatide offered greater weight loss benefits than semaglutide.
DAIC
DECEMBER 3, 2024
tim.hodson Tue, 12/03/2024 - 16:52 Nov. 18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with Peripheral Artery Disease (PAD) who were unable or unwilling to take statin medications. These data were presented at the 2024 American Heart Association Scientific Sessions, in Chicago, IL. Additionally, two exploratory analyses from the CLEAR Outcomes trial and a real-world analysis of bempedoic acid usage were presented at the conference.
Med Page Today
DECEMBER 5, 2024
(MedPage Today) -- In part two of this three-part Instagram Live discussion, MedPage Today editor-in-chief Jeremy Faust, MD, Karl Nadolsky, DO, and Fatima Cody Stanford, MD, MPH, MPA, MBA, dive into the complexities of GLP-1 receptor agonists.
American Heart News - Heart News
DECEMBER 4, 2024
Research Highlights: An analysis of more than 1,300 stroke survivors found that women were less likely than their male counterparts to take medications, such as cholesterol-lowering statins and blood thinning medications to prevent blood clots, to.
Science Daily - Heart Disease
DECEMBER 2, 2024
A cancer therapy that prompts the body's immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke. A possible explanation for this side effect is that the treatment interferes with immune regulation in the heart's largest blood vessels, a new study suggests.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Ku70, a DNA repair protein, binds to the damaged DNA ends and orchestrates the recruitment of other proteins to facilitate repair of DNA double-strand breaks. Besides its essential role in DNA repair, several studies have highlighted nonclassical functions of Ku70 in cellular processes. However, its function in immune homeostasis and antitumor immunity remains unknown.
Heart Sisters
DECEMBER 1, 2024
Just 24 days to go before Santa slides down our chimneys! What’s your favourite suggestion for heart patient gifts this year?
Med Page Today
DECEMBER 4, 2024
(MedPage Today) -- Eating more dark chocolate was associated with a lower risk of type 2 diabetes, an analysis of prospective cohort studies suggested. Among participants across three studies of healthcare workers, those who consumed ≥5.
HCPLive
DECEMBER 4, 2024
Women who gave birth after infertility without receiving fertility treatments had an elevated risk of developing SARDs, such as lupus.
Science Daily - Heart Disease
DECEMBER 4, 2024
New research shows that the heart has a mini-brain -- its own nervous system that controls the heartbeat. A better understanding of this system, which is much more diverse and complex than previously thought, could lead to new treatments for heart diseases.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Metabolic dysfunction–associated steatotic hepatitis (MASH) is a chronic progressive liver disease that is highly prevalent worldwide. MASH is characterized by hepatic steatosis, inflammation, fibrosis, and liver damage, which eventually result in liver dysfunction due to cirrhosis or hepatocellular carcinoma. However, the cellular and molecular mechanisms underlying MASH progression remain largely unknown.
ECG Cases
DECEMBER 3, 2024
On this month's EM Quick Hits podcast: Ross Prager on TEE in cardiac arrest, Justin Morgenstern on nebulized ketamine for analgesia in the ED, Hans Rosenberg & Krishin Yadav on standardizing cellulitis management, Mathew McArther on latest studies on subcutaneous insulin protocols in DKA, Jennifer C. Tang on documenting differential diagnoses medicolegal tips.
Med Page Today
DECEMBER 4, 2024
(MedPage Today) -- Serious outcomes associated with metabolic dysfunction-associated steatotic liver disease (MASLD) -- including liver cancer, cirrhosis, heart disease, and more -- affect men and women differently, a large cohort study of.
HCPLive
DECEMBER 5, 2024
These data highlight some of the most notable findings related to airline travel issues among those with food allergies or with family members with such allergies.
Science Daily - Heart Disease
DECEMBER 2, 2024
A critical review of cell-based and cell product-based therapies for the treatment of heart failure details 20 years of completed and ongoing clinical trials. While none has yet gained medical approval, pathways to new treatments for heart failure can take decades, as seen for two other, now accepted therapies.
Journal of Clinical Investigation - Cardiology
DECEMBER 2, 2024
Type I IFNs (IFN-Is) induced by radiotherapy (RT) are critical for its efficacy, while the mechanism by which tumor cells inhibit IFN-I production remains largely unsolved. By an unbiased CRISPR screen, we identified hemeoxygenase 1 (HO-1) as an RT-related regulator of IFN-I production. Mechanistically, the ER-anchored, full-length HO-1 disrupted stimulator of IFN genes (STING) polymerization and subsequent coat protein complex II–mediated (COPII-mediated) ER-Golgi transportation, leading to ham
Dr. Paddy Barrett
NOVEMBER 30, 2024
Aaaaaaaand…… now today is the correct day for this email to go out. Not on Tuesday, as it inadvertently did. Our publishing platform has been letting us down recently with scheduling glitches, so if you have received any duplicate emails - our apologies for that. Just a reminder that you can get access to the Heart Health Formula for 30% off.
Dr. S. Venkatesan MD
DECEMBER 3, 2024
The following thought, is in response to a spate of violent attacks by patients on the doctors in my state. One of my ex-colleagues, an Oncologist was stabbed with a knife by a son of an elderly mother in his clinic room, apparently agitated with the side effects of the chemotherapeutic drugs she was receiving for end-stage Hodgkin’s lymphoma.
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