Frontiers in Cardiovascular Medicine

NOVEMBER 26, 2024

Cardiovascular disease (CVD) is responsible for approximately 30% of annual global mortality rates, yet existing treatments for this condition are considered less than ideal. Consequently, there has been a notable increase in interest towards drug targets targeting lactylation in immune cells, prompting further exploration.

Cardiovascular Disease 59

Cardiovascular Disease Article 59

Frontiers in Cardiovascular Medicine

JULY 16, 2025

The human gut microbiota influences host metabolism, immune responses, and inflammation, with microbial dysbiosis linked to metabolic disorders and increased cardiovascular disease risk.

Cardiovascular Disease 52

Cardiovascular Disease Atherosclerosis 52

Frontiers in Cardiovascular Medicine

JULY 11, 2025

Iron deficiency (ID) is common in patients with cardiovascular disease. Up to 60% of patients with coronary artery disease and even higher percentages of patients with heart failure (HF) or pulmonary hypertension have ID. Malnutrition has also been linked to cardiovascular disease.

Cardiovascular Disease 52

Cardiovascular Disease Arrhythmia Coronary Artery Disease Quality of Life 52

Frontiers in Cardiovascular Medicine

JUNE 24, 2025

The pathogenesis of atherosclerotic cardiovascular disease is complex, involving multiple cell types and biological processes. Extracellular Vesicles (EVs) are small, cell-derived particles increasingly recognized for their role in cardiovascular diseases.

Cardiovascular Disease 52

Cardiovascular Disease Atherosclerosis Plaque Biomarkers 52

Frontiers in Cardiovascular Medicine

MARCH 28, 2025

BackgroundThere is a growing body of evidence indicating that metabolites are associated with an increased risk of cardiovascular diseases (CVDs), the underlying causality of these associations remains largely unchallenged. After Bonferroni correction, causal associations were found to be significant with p-values less than 0.05.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Aneurysm Heart Failure 52

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

Cardiovascular disease (CVD) remains a global health burden despite advances in prevention and treatment. Conventional biomarkers, while effective for a number of patient groups, fail to provide personalized diagnosis and prognosis, necessitating the exploration of novel markers.

Cardiovascular Disease 52

Cardiovascular Disease Circulation Biomarkers Risk Factors 52

Frontiers in Cardiovascular Medicine

JUNE 26, 2025

The escalating recognition of perivascular adipose tissue (PVAT) as a molecular nexus in cardiovascular disease (CVD) pathogenesis necessitates a comprehensive synthesis of its spatiotemporal dynamics and therapeutic potential.

Cardiovascular Disease 52

Cardiovascular Disease Pharmacology Biomarkers Obesity 52

Frontiers in Cardiovascular Medicine

MAY 25, 2025

Numerous studies have demonstrated the part that gut microbiota and its metabolites play in the development and course of several illnesses, including colon cancer, heart failure, stroke, hypertension, and inflammatory bowel disease.

Cardiovascular Disease 52

Cardiovascular Disease Heart Failure Atherosclerosis Hypertension 52

Medical Xpress - Cardiology

NOVEMBER 14, 2024

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.

Cholesterol 128

Cholesterol Cardiovascular Disease Heart attacks Heart Attack 128

HCPLive

JUNE 11, 2025

Potentially the first successful CETP inhibitor, obicetrapib has shown positive trial results in reducing the risk of cardiovascular disease when combined with statins.

Cardiovascular Disease 59

Cardiovascular Disease 59

Frontiers in Cardiovascular Medicine

MAY 18, 2025

Cardiovascular diseases (CVD) remain the primary cause of morbidity and mortality in developed countries, highlighting the urgent need to identify biomarkers associated with CVD and its risk factors.

Cardiovascular Disease 52

Cardiovascular Disease Coronary Artery Disease Risk Factors Diabetes 52

Frontiers in Cardiovascular Medicine

FEBRUARY 27, 2025

However, it remains unclear which type of exercise is most effective for managing AS, particularly in individuals at high risk for cardiovascular diseases (CVD). BackgroundPrevious studies have shown that exercise can improve arterial stiffness (AS).

Exercise 52

Exercise Cardiovascular Disease Blood Pressure Education 52

Medical Xpress - Cardiology

JULY 11, 2025

Cardiovascular disease (CVD) risk prediction models have improved the ability to stratify adults across the CVD risk spectrum.

Cardiovascular Disease 40

Cardiovascular Disease Research 40

Science Daily - Heart Disease

DECEMBER 2, 2024

Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study. According to the researchers, these risk reductions are likely driven by the replacement of red and processed meats with plant proteins.

Diet 115

Diet Cardiovascular Disease Heart Disease Research 115

HCPLive

MAY 28, 2025

Yale researchers unveil a groundbreaking 3D-bioprinted synthetic aorta, promising revolutionary advancements in cardiovascular disease treatment and patient care.

Cardiovascular Disease 52

Cardiovascular Disease Patient Care Research 52

Open Heart

MARCH 13, 2025

Background Observational studies have reported that sleep is associated with the risk of major depressive disorder (MDD) and cardiovascular diseases (CVDs). However, the causal relationships among various sleep traits remain contentious, and whether MDD mediates the impact of specific sleep traits on CVDs is unclear.

Cardiovascular Disease 52

Cardiovascular Disease Coronary Artery Disease Myocardial Infarction Atrial Fibrillation 52

American Heart News - Heart News

MAY 15, 2025

Statement Highlights: Palliative care is specialized medical care focused on easing symptoms, addressing psychological and spiritual needs, and helping patients and caregivers make critical decisions aligned with their personal beliefs and values.

Cardiovascular Disease 94

Cardiovascular Disease 94

Frontiers in Cardiovascular Medicine

JULY 14, 2025

BackgroundThere is currently no information on the association between the fasting blood glucose/high-density lipoprotein cholesterol ratio (FBG/HDL-C) and cardiovascular disease (CVD) incidence.MethodsParticipants in our study, sourced from the China Health and Retirement Longitudinal Study, were grouped into quartiles by FBG/HDL-C ratio.

Cholesterol 52

Cholesterol Cardiovascular Disease Heart Disease Strokes 52

Frontiers in Cardiovascular Medicine

JULY 13, 2025

MethodsData were obtained from the China Health and Retirement Longitudinal Study (CHARLS), including a total of 7,812 middle-aged and older adults.

Cardiovascular Disease 52

Cardiovascular Disease Diabetes Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2025

BackgroundCurrent evidence suggests that cardiovascular disease (CVD) plays a role in the progression of chronic obstructive pulmonary disease (COPD). However, the relationship between CVD and the severity of COPD remains inadequately understood.

Cardiovascular Disease 52

Cardiovascular Disease Pulmonary BMI Hypertension 52

Medical Xpress - Cardiology

MAY 10, 2025

Women who experience infertility are more likely to develop heart and blood vessel conditions later in life, with younger women and those who undergo fertility treatments at a greater risk.

Cardiovascular Disease 65

Cardiovascular Disease Pediatrics 65

Frontiers in Cardiovascular Medicine

APRIL 23, 2025

Despite clinical observations of Baduanjin's cardiovascular benefits, systematic evidence for older adults remains limited. Moreover, the effects of Baduanjin exercise on functional capacity in older adults with cardiovascular diseases have not been adequately investigated.

Exercise 52

Exercise Cardiovascular Disease Cardiac Function Biomarkers 52

Frontiers in Cardiovascular Medicine

JUNE 19, 2025

AimEpidemiological and genetic studies have shown that elevated basal remnant cholesterol (RC) levels increase cardiovascular disease (CVD) risk. However, the relationship between RC dynamics and CVD remains unclear.

Cholesterol 52

Cholesterol Cardiovascular Disease Heart Disease Research 52

Circulation

FEBRUARY 13, 2025

Critical care cardiology refers to the practice focus of and subspecialty training for the comprehensive management of life-threatening cardiovascular diseases and comorbid conditions that require advanced critical care in an intensive care unit. Circulation, Ahead of Print.

Critical Care 72

Critical Care Myocardial Infarction Research Cardiovascular Disease 72

Frontiers in Cardiovascular Medicine

JUNE 9, 2025

ObjectiveThe purpose of this study was to investigate the correlation between plasma homocysteine (Hcy) levels and cardiovascular disease (CVD) in United States adults based on the National Health and Examination Survey (NHANES) database of the United States.MethodsData from two survey periods (2003–2006) in the NHANES database were used as the research (..)

Cardiovascular Disease 52

Cardiovascular Disease Obesity Education Diabetes 52

All About Cardiovascular System and Disorders

JULY 5, 2025

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease. The post Clonal hematopoiesis of indeterminate potential (CHIP) and cardiovascular disease appeared first on All About Cardiovascular System and Disorders. 2021.07.004.

Cardiovascular Disease 52

Cardiovascular Disease Coronary Artery Disease Myocardial Infarction Heart Failure 52

JAMA Cardiology

JUNE 3, 2025

Quantitative risk estimation is the starting point for decisions regarding use of drug therapy to reduce events in primary prevention of atherosclerotic cardiovascular disease (ASCVD). Equations that predict 10-year risk have steadily improved in their content, relevance, accuracy, and precision over time.

Cardiovascular Disease 89

Cardiovascular Disease 89

Frontiers in Cardiovascular Medicine

FEBRUARY 18, 2025

BackgroundLimited evidence exists regarding the association between oxidative stress induced by dietary and lifestyle factors and cardiovascular diseases (CVDs).MethodsWe The total oxidative balance score (OBS) was derived from 20 oxidative stress-related exposures, including dietary and lifestyle factors.

Cardiovascular Disease 52

Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

JULY 1, 2025

Atherosclerosis (AS) is a major cause of cardiovascular disease morbidity and mortality, characterized by lipid accumulation, oxidative stress, and chronic inflammation. Natural organic sulfur compounds (OSCs), especially those derived from garlic (Allium sativum), have therapeutic value in slowing the course of AS.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Cholesterol Research 52

Nature Reviews - Cardiology

JULY 17, 2025

Nature Reviews Cardiology, Published online: 18 July 2025; doi:10.1038/s41569-025-01193-4 Seyed Soheil Saeedi Saravi discusses the seminal study that linked a gut microbial metabolite to atherosclerotic cardiovascular disease and opened the way to mechanistic studies assessing how the gut microbiota influences host cardiovascular health.

Cardiovascular Disease 42

Cardiovascular Disease Risk Factors 42

Nature Reviews - Cardiology

FEBRUARY 27, 2025

Nature Reviews Cardiology, Published online: 28 February 2025; doi:10.1038/s41569-025-01143-0 Epigenetic editing holds great promise for the treatment of many diseases, including cardiovascular disease.

Cardiovascular Disease 87

Cardiovascular Disease Technology 87

Frontiers in Cardiovascular Medicine

DECEMBER 9, 2024

PurposeThis study explores the correlation between sleep duration and cardiovascular disease (CVD) among middle-aged and older adults in China.

Cardiovascular Disease 52

Cardiovascular Disease Research 52

Nature Reviews - Cardiology

MARCH 19, 2025

Nature Reviews Cardiology, Published online: 20 March 2025; doi:10.1038/s41569-025-01142-1 In this Review, Ravindran and Gustafsson describe the mechanisms involved in regulating mitochondrial quality control in cardiomyocytes, discuss how these pathways are altered in cardiovascular disease and ageing, and highlight the therapeutic potential of targeting (..)

Cardiovascular Disease 62

Cardiovascular Disease 62

Frontiers in Cardiovascular Medicine

FEBRUARY 13, 2025

IntroductionThis paper aims to expose the link between occupational exposure to respirable crystalline silica (SiO2) and cardiovascular diseases (CVDs).MethodsA Specific cardiovascular diseases, such as acute myocardial infarction, arrhythmias, pulmonary hypertension and pericarditis, were also pointed.

Myocardial Infarction 52

Myocardial Infarction Biomarkers Cardiovascular Disease Pericarditis 52

Medical Xpress - Cardiology

JULY 6, 2025

have linked brighter night-time light exposure to elevated risks of five major cardiovascular diseases. Flinders Health and Medical Research Institute researchers, along with colleagues in the UK and U.S.,

Cardiovascular Disease 111

Cardiovascular Disease Outcomes Research 111

European Journal of Cardiovascular Nursing

JUNE 10, 2025

Abstract Aim The aim of this study was to investigate the associations between interoceptive sensibility and self-care behaviors in individuals with cardiovascular disease. Methods and Results Adults with cardiovascular disease were recruited for this cross-sectional descriptive study.

Cardiovascular Disease 40

Cardiovascular Disease 40

Frontiers in Cardiovascular Medicine

MAY 12, 2025

BackgroundAlthough the cardiometabolic index (CMI) has gained recognition as a new tool for evaluating metabolic health, the relationship between CMI and cardiovascular disease (CVD) remains unclear.

Cardiovascular Disease 40

Cardiovascular Disease Research 40