Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.

Aortic valve 124

Aortic valve Aortic Outcomes Thrombosis 124

JAMA Cardiology

FEBRUARY 11, 2025

This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.

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Aortic valve Aortic Stenosis 105

JAMA Cardiology

OCTOBER 15, 2024

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

Aortic valve 101

Aortic valve Heart Failure Aortic Stenosis 101

Journal of Cardiothoracic Surgery

FEBRUARY 4, 2025

Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis. Its performance appears to be equal to or better than many other bioprosthetic valves. Results The technical success rate was almost perfect in all studies.

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Aortic valve Aortic Outcomes Article 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

A 70-year-old female patient with a history of bioprosthetic aortic valve replacement and coronary artery bypass graft presented with bioprosthetic valve failure secondary to prosthetic valve endocarditis. This resulted in early death due to myocardial infarction and acute heart failure.

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Aortic valve Coronary Artery Bypass Graft Thrombosis Aortic 52

DAIC

JUNE 7, 2024

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

Aortic valve 105

Aortic valve Aortic Heart Valves Pharmacology 105

Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2

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Aortic valve Bicuspid/Mitral Aortic Aneurysm 52

Med Page Today

JANUARY 26, 2025

(MedPage Today) -- LOS ANGELES -- Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry.

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Aortic valve Aortic Outcomes 105

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesispatient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement.

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Aortic valve Aortic TAVR Myocardial Infarction 52

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

Aortic valve 105

Aortic valve Bicuspid/Mitral Aortic Research 105

DAIC

DECEMBER 12, 2023

milla1cf Tue, 12/12/2023 - 07:00 December 12, 2023 — Patients who received the anticoagulant drug warfarin after bioprosthetic aortic valve replacement had lower incidence of mortality and a decreased risk of blood clots, according to a retrospective study published in Mayo Clinic Proceedings.

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Aortic valve Aortic Blood Clot Medicare 116

Heart BMJ

JANUARY 29, 2025

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Multidimensional CT (MDCT) is the main imaging mortality for the diagnosis of SLT but it enhances the risk of contrast-induced nephropathy.

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Aortic valve Thrombosis Aortic Technology 52

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

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Aortic valve Aortic Quality of Life TAVR 98

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

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Aortic valve Aortic TAVR Peripheral Arterial Disease 98

JAMA Cardiology

AUGUST 13, 2024

This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.

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Aortic valve Aortic 91

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

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Aortic valve TAVR Aortic Outcomes 111

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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Aortic valve Aortic Stenosis Research 75

American College of Cardiology

MAY 24, 2024

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

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Aortic valve Aortic Stenosis Article 70

Society of Thoracic Surgeons - Adult Cardiac

JANUARY 26, 2025

Shettys team followed 252 patients who underwent the Ross procedure, a heart valve replacement operation commonly used to treat younger patients with severe aortic valve disease.

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Aortic valve Cardiothoracic Aortic Congenital 83

Science Daily - Heart Disease

JANUARY 15, 2025

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

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Aortic valve Bicuspid/Mitral Aortic 76

Open Heart

JANUARY 8, 2024

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.

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Aortic valve Aortic Preserved Ejection Fraction Stenosis 98

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

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Aortic valve Cancer Aortic TAVR 98

JAMA Cardiology

MAY 14, 2024

This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).

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Aortic valve Aortic TAVR Outcomes 69

Heart BMJ

FEBRUARY 26, 2025

In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.

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Aortic valve Aortic Stenosis 59

Journal of Cardiothoracic Surgery

MARCH 7, 2025

Quadricuspid aortic valve (QAV) is a rare congenital anomaly of the aortic valve, with an incidence of 0.05-0.1%, 0.1%, often associated with aortic regurgitation. The condition typically presents between the ages o.

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Aortic valve Aortic Congenital 52

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Objectives To evaluate the results of the inoperable and operable with aortic valve endocarditis, focus on risk factors, significance, and management of destruction of the aortic annulus in aortic valve endocarditis.

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Aortic valve Aortic Best Practices Risk Factors 64

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

The co-occurrence of a bicuspid aortic valve (BAV) with TSC is exceedingly rare.Case summaryWe report the case of a 26-year-old woman with genetically confirmed TSC, harboring a novel pathogenic variant in the TSC2 gene. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone.

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Aortic valve Bicuspid/Mitral Aortic Heart Valves 52

Science Daily - Heart Disease

JUNE 5, 2024

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification.

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Aortic valve Aortic Risk Factors Research 66

Heart BMJ

JUNE 25, 2024

A transthoracic echocardiogram (TTE) revealed a mobile mass on the right coronary cusp of the aortic valve ( figure 1 , ). cm) at the right coronary cusp of the aortic valve on the long-axis and short-axis parasternal view. Figure 1 A mobile mass (1.88 Question What is the most likely diagnosis?

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Aortic valve Aortic Chest Pain Atrial Fibrillation 59

Open Heart

MARCH 3, 2025

Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown.

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Congenital Aortic Stenosis Aortic valve 52

DAIC

FEBRUARY 22, 2024

He previously served on the HVS Board of Directors and has led the HVS AVIATOR Registry, an international registry examining outcomes after aortic valve surgery. I am very excited and honored to lead the Heart Valve Society and further consolidate its role as a unique society dedicated to valvular heart disease.

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Heart Valves Aortic valve Aortic Sudden Cardiac Death 142

Society of Thoracic Surgeons - Congenital

JANUARY 8, 2025

News Increased Risk of Surgical Aortic Valve Replacement After Prior Transcatheter vs. Surgical Aortic Valve Replacement with Concomitant Valve Disease pvaldez Wed, 01/08/2025 - 09:50 2 min read

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Aortic valve Aortic 52

Circulation: Cardiovascular Interventions

DECEMBER 28, 2023

BACKGROUND:A high permanent pacemaker implantation (PPI) risk remains a concern of self-expandable transcatheter aortic valve implantation, despite the continued improvements in implantation methodology. There were no group differences in 30-day all-cause mortality (1.4% versus 0%;P=0.608).CONCLUSIONS:Our

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Aortic valve Aortic Pacemaker Cardiovascular Interventions 76

Frontiers in Cardiovascular Medicine

NOVEMBER 21, 2024

Although enzyme replacement therapy (ERT) was initiated immediately after diagnosis, the patient experienced aortic valve damage and left heart enlargement 2 years later. Subsequently, the patient underwent transcatheter aortic valve replacement.

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Cardiomyopathy Aortic valve Aortic Hospital 52

Medical Xpress - Cardiology

FEBRUARY 24, 2025

Aortic valve stenosis (AVS) is a significant health concern affecting over 1.5 million Americans and millions more globally. Researchers at Mayo Clinic are exploring the use of a new drug called ataciguat to manage AVS.

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Aortic valve Aortic Stenosis Research 49

DAIC

SEPTEMBER 4, 2024

1, 2024 — Researchers at UTHealth Houston have identified genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications. tim.hodson Wed, 09/04/2024 - 15:53 Sept.

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Research 52

Journal of Cardiothoracic Surgery

MARCH 25, 2024

This is a case report of a 78-year-old male who underwent a sub-coronary aortic valve and root replacement due to valve dehiscence and aortic root pseudoaneurysm. The patient had complex anomalous coronary ana.

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Aortic valve Aortic 59