Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Here, we examined the therapeutic potential of itaconate in atherosclerosis. Deletion of Acod1 in myeloid cells exacerbated inflammation and atherosclerosis in vivo and resulted in an elevated frequency of a specific subset of M1-polarized proinflammatory macrophages in the atherosclerotic aorta.

Atherosclerosis 98

Atherosclerosis Cholesterol 98

Nature Reviews - Cardiology

APRIL 9, 2024

Nature Reviews Cardiology, Published online: 10 April 2024; doi:10.1038/s41569-024-01016-y In this Review, Kemper and colleagues discuss the canonical and non-canonical roles of the complement system in the pathogenesis of atherosclerosis and discuss potential new therapeutic strategies targeting the complement system for the prevention and treatment (..)

Atherosclerosis 82

Atherosclerosis Cardiovascular Disease 82

Medical Xpress - Cardiology

DECEMBER 12, 2023

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes, and coronary artery disease.

Heart Attack 105

Heart Attack Heart attacks Atherosclerosis Coronary Artery Disease 105

Nature Reviews - Cardiology

APRIL 24, 2024

Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01023-z In this Review, the authors discuss the receptors, ligands and interactors that regulate immune cell recruitment in atherosclerosis, describe mechanisms that promote the resolution of inflammation in atherosclerotic lesions, and highlight potential strategies (..)

Atherosclerosis 65

Atherosclerosis Cardiovascular Disease 65

Frontiers in Cardiovascular Medicine

APRIL 4, 2024

Biomechanical forces, including vascular shear stress, cyclic stretching, and extracellular matrix stiffness, which influence mechanosensitive channels in the plasma membrane, determine cell function in atherosclerosis.

Atherosclerosis 52

Atherosclerosis Plaque 52

American College of Cardiology

APRIL 15, 2024

The following are key points to remember from a state-of-the-art review on the long-term safety of low-dose colchicine for atherosclerosis.

Atherosclerosis 75

Atherosclerosis Article 75

Medical Xpress - Cardiology

JANUARY 24, 2024

Atherosclerosis, a chronic inflammatory disease of the inner walls of blood vessels, is responsible for many cardiovascular conditions. Dendritic cells, which act to recognize foreign substances in the body and mount an immune response, play an important role in the disease.

Atherosclerosis 102

Atherosclerosis Research 102

Nature Reviews - Cardiology

MARCH 11, 2024

Nature Reviews Cardiology, Published online: 12 March 2024; doi:10.1038/s41569-024-01007-z Shoaran and Maffia recount how our understanding of the role of inflammation in atherosclerosis has evolved and highlight the study by Göran Hansson and colleagues that provided the first hint of the involvement of the adaptive immune response in atherosclerosis. (..)

Atherosclerosis 50

Atherosclerosis 50

Frontiers in Cardiovascular Medicine

JULY 24, 2024

ObjectiveThis study aimed to investigate the prevalence of carotid atherosclerosis (CAS), especially among seniors, and develop a precise risk assessment tool to facilitate screening and early intervention for high-risk individuals.MethodsA comprehensive approach was employed, integrating traditional epidemiological methods with advanced machine learning (..)

Atherosclerosis 52

Atherosclerosis Cholesterol Blood Pressure Risk Factors 52

Medical Xpress - Cardiology

MARCH 22, 2024

Atherosclerosis is the major contributor to cardiovascular mortality worldwide. Diet-induced metabolic abnormalities including obesity, hyperglycemia, dyslipidemia, insulin resistance (IR), and non-alcoholic fatty liver disease are considered atherogenic risk factors.

Atherosclerosis 88

Atherosclerosis Diet Obesity Risk Factors 88

Frontiers in Cardiovascular Medicine

JUNE 17, 2024

BackgroundWhile Traditional Chinese Medicine (TCM) boasts an extensive historical lineage and abundant clinical expertise in addressing atherosclerosis, this field is yet to be penetrated adequately by bibliometric studies. The Journal of Ethnopharmacology leads with the most publications and boasts the greatest total number of citations.

Atherosclerosis 52

Atherosclerosis Research Article Circulation 52

Frontiers in Cardiovascular Medicine

JULY 11, 2024

The research progress of endoplasmic reticulum (ER) stress in atherosclerosis (AS) is of great concern. The ER, a critical cellular organelle, plays a role in important biological processes including protein synthesis, folding, and modification.

Atherosclerosis 52

Atherosclerosis Research 52

Science Daily - Stroke

JANUARY 13, 2024

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.

Atherosclerosis 79

Atherosclerosis Research 79

Nature Reviews - Cardiology

JANUARY 1, 2024

In this Review, De Meyer and colleagues describe the various forms of programmed macrophage death in atherosclerosis and the potential therapeutic implications.

Atherosclerosis 85

Atherosclerosis Plaque 85

Frontiers in Cardiovascular Medicine

MARCH 21, 2024

Introduction The progression of coronary atherosclerosis is an active and regulated process. The Wnt signaling pathway is thought to play an active role in the pathogenesis of several cardiovascular diseases; however, a better understanding of this system in atherosclerosis is yet to be unraveled.

Atherosclerosis 64

Atherosclerosis Cholesterol Plaque Cardiovascular Disease 64

Med Page Today

DECEMBER 4, 2023

(MedPage Today) -- The link between childhood blood pressure (BP) and adult atherosclerosis appeared stable going all the way back to infancy, suggesting that efforts to prevent arterial thickening may be beneficial starting at the earliest life.

Blood Pressure 76

Blood Pressure Atherosclerosis 76

Medical Xpress - Cardiology

JANUARY 15, 2024

A new 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials in a paper titled "Atherosclerotic three-layer nanomatrix (..)

Atherosclerosis 85

Atherosclerosis Research 85

Medical Xpress - Cardiology

JANUARY 23, 2024

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid have found that one of the most potent genetic risk factors for Alzheimer's disease, apolipoprotein E4 (APOE4), is also associated with an increased risk of developing subclinical atherosclerosis in middle age.

Atherosclerosis 81

Atherosclerosis Risk Factors 81

Science Daily - Heart Disease

APRIL 30, 2024

Researchers have discovered that the smooth muscle cells that line the arteries of people with atherosclerosis can change into new cell types and develop traits similar to cancer that worsen the disease.

Atherosclerosis 56

Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 56

American College of Cardiology

JULY 1, 2024

This expert opinion is based on Primary Prevention of Subclinical Atherosclerosis in Young Adults: JACC Review Topic of the Week.

Atherosclerosis 61

Atherosclerosis Article 61

Frontiers in Cardiovascular Medicine

APRIL 18, 2024

Inflammation and dyslipidemia are critical inducing factors of atherosclerosis. However, synthesized PPAR agonists exhibit contrary therapeutic effects and various side effects in atherosclerosis therapy. However, synthesized PPAR agonists exhibit contrary therapeutic effects and various side effects in atherosclerosis therapy.

Atherosclerosis 52

Atherosclerosis Article Research 52

The British Journal of Cardiology

JUNE 14, 2024

Designed to give healthcare professionals an understanding of lipid metabolism and its role in atherosclerosis. Module first published 9 July 2015 Module first revised 17 March 2021 Second revision June 2024

Atherosclerosis 52

Atherosclerosis 52

Frontiers in Cardiovascular Medicine

JANUARY 9, 2024

Atherosclerosis is a chronic inflammatory disease characterized by endothelial dysfunction and plaque formation. Under pro-inflammatory conditions, endothelial cells can undergo endothelial-to-mesenchymal transition (EndMT), contributing to atherosclerosis development.

Atherosclerosis 59

Atherosclerosis Plaque Cardiovascular Disease 59

Frontiers in Cardiovascular Medicine

JUNE 12, 2024

Atherosclerosis (AS) is a complex disease caused by multiple pathological factors threatening human health-the pathogenesis is yet to be fully elucidated.

Atherosclerosis 52

Atherosclerosis Plaque Research 52

Frontiers in Cardiovascular Medicine

JULY 16, 2024

Atherosclerosis was evaluated at the endpoint of experiments. cholesterol for 16 weeks. Plasma lipid levels, lipoproteins, and apolipoproteins were analyzed.

Atherosclerosis 52

Atherosclerosis Cholesterol Diet Aortic 52

Medical Xpress - Cardiology

FEBRUARY 22, 2024

Men who were physically fit when they were young had a lower risk of atherosclerosis almost 40 years later, according to a study led by researchers at Linköping University, Sweden.

Atherosclerosis 45

Atherosclerosis Cardiovascular Disease Research 45

Frontiers in Cardiovascular Medicine

FEBRUARY 29, 2024

So far, researchers have focused on the significance of silicon for the development of bones and connective tissue, and its role in preventing neurodegenerative diseases and atherosclerosis. Despite numerous studies, the role of silicon as an active element in the human body is poorly understood.

Atherosclerosis 64

Atherosclerosis Article Research 64

Frontiers in Cardiovascular Medicine

JUNE 16, 2024

These innovative strategies hold promise for improving the management of atherosclerosis in the near future. Based on these mechanisms, we discuss novel therapeutic approaches that have been developed to regulate the generation of intimal foam-like cells.

Atherosclerosis 52

Atherosclerosis Plaque Physiology Innovation 52

Journal of Cardiovascular Pharmacology

NOVEMBER 16, 2023

This modification will affect not only the onset of diabetes but also the related onset of atherosclerosis. Therefore, in this review, based on the whole process of atherosclerosis evolution, we explored the possible existence of acetylation/deacetylation caused by diabetes.

Atherosclerosis 40

Atherosclerosis Diabetes Cardiovascular Disease Article 40

Cardiovascular Ultrasound

JANUARY 9, 2024

This study aimed to evaluate atherosclerosis as comorbidity by measuring the carotid (bulb and common carotid artery) Carotid intima-media thickness in COPD-diagnosed patients and to evaluate the relationship.

Atherosclerosis 52

Atherosclerosis Risk Factors Research 52

Cardiovascular Diabetology

JANUARY 8, 2024

Atherosclerosis is one of the leading causes of death worldwide. miR-26 is a potential biomarker of atherosclerosis. Standardized diagnostic tests for miR-26 (MIR26-DX) have been developed, but the fastest pro.

Atherosclerosis 52

Atherosclerosis Biomarkers 52

Frontiers in Cardiovascular Medicine

JULY 2, 2024

It is proven challenging managing chronic cardiovascular illnesses like atherosclerosis, arrhythmias, and diverse cardiomyopathies. This aroused interest among the specialised scientific community, seeking for solutions based on non-clinical and clinical investigations, to shed light onto the physio-pathology of cardiovascular impairment.

Atherosclerosis 52

Atherosclerosis Cardiovascular Disease Biomarkers Physiology 52

Science Daily - Stroke

NOVEMBER 2, 2023

Researchers have demonstrated the specific role microRNA plays in atherosclerosis -- and how it manages to intervene in this signaling pathway.

Atherosclerosis 40

Atherosclerosis Research 40

Nature Reviews - Cardiology

DECEMBER 17, 2023

Nature Reviews Cardiology, Published online: 18 December 2023; doi:10.1038/s41569-023-00982-z Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention

Atherosclerosis 40

Atherosclerosis 40

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundThe relationship between depression and subclinical coronary atherosclerosis in asymptomatic individuals is not clear. The degree and extent of subclinical coronary atherosclerosis were evaluated by coronary computed tomographic angiography, and ≥50% diameter stenosis was defined as significant. 2.03];P=0.450).

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

Journal of the American Heart Association

JANUARY 12, 2024

BackgroundUltraviolet B (UV‐B) irradiation is an effective treatment for human cutaneous disorders and was shown to reduce experimental atherosclerosis by attenuating immunoinflammatory responses. Our findings indicate that a novel 282 nm UV‐B phototherapy could be an attractive approach to treat atherosclerosis.

Atherosclerosis 45

Atherosclerosis Plaque Aortic Technology 45

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG).

Coronary Artery Bypass Graft 64

Coronary Artery Bypass Graft Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease 64