Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.

Heart Transplant 52

Heart Transplant Transplant Pediatrics Heart Failure 52

HCPLive

JUNE 7, 2025

Study findings highlight the potential utility of cardiac catheterization as a targeted intervention in pre-kidney transplant cardiac risk stratification.

Transplant 64

Transplant 64

Nature Reviews - Cardiology

JANUARY 1, 2025

Nature Reviews Cardiology, Published online: 02 January 2025; doi:10.1038/s41569-024-01109-8 In this Review, Lavine and colleagues describe the known subsets of cardiac macrophages, highlighting newly identified macrophage states and associated cellular neighbourhoods, and discuss the roles of cardiac macrophages in homeostasis and disease, including (..)

Transplant 70

Transplant Arrhythmia 70

Medical Xpress - Cardiology

JUNE 17, 2025

In this cohort, more than 30% survived without a transplant to at least 35 years of age. Researchers at Children's Hospital of Philadelphia (CHOP) reported long-term clinical outcomes for the largest single center cohort of individuals who underwent complex reconstructive surgery for hypoplastic left heart syndrome as newborns.

Transplant 40

Transplant Research Hospital Outcomes 40

Journal of the American Heart Association

JULY 3, 2025

To further investigate this process, we developed a mouse model enabling the surgical removal and transplantation of adventitial tissue.ResultsWe observed that activated adventitial fibroblasts release interleukin 6 and other cytokines, which strongly induce SMC proliferation and migration in vitro.

Transplant 45

Transplant Angioplasty 45

Journal of the American Heart Association

JUNE 5, 2025

In‐hospital mortality and index hospitalization transplant were highest among HP (25.6%, 8.5%) compared with DSP (13.8%, 0.8%) and SP (11.3%, 0.9%) (P<0.001). HP, however, was associated with higher in‐hospital mortality and index hospitalization transplant.

Transplant 40

Transplant Hospital Outcomes Pulmonary 40

Frontiers in Cardiovascular Medicine

APRIL 23, 2025

Chronic allograft vasculopathy (CAV) is a major cause of late graft failure in heart transplant recipients, characterized by progressive intimal thickening and diffuse narrowing of the coronary arteries.

Heart Transplant 52

Heart Transplant Transplant Technology Atherosclerosis 52

HCPLive

JUNE 8, 2025

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SCAD 114

SCAD Outcomes Cerebrovascular Disease Heart Failure 114

Science Daily - Heart Disease

MAY 19, 2025

A new discovery could mean more donor hearts are available for heart transplant, giving more people a second chance at life.

Heart Transplant 62

Heart Transplant Transplant 62

Journal of the American Heart Association

JULY 3, 2025

Journal of the American Heart Association, Ahead of Print.

Transplant 40

Transplant 40

Journal of the American Heart Association

JUNE 30, 2025

Baseline evaluation was defined as the echocardiogram performed at the time of referral, before the occurrence of a MACE, including appropriate implantable cardioverter‐defibrillator intervention, myomectomy, heart transplant, or cardiac death.ResultsThe MACE group showed significantly decreased left ventricular peak longitudinal strain compared with (..)

Pediatrics 40

Pediatrics Cardiomyopathy Heart Transplant Echocardiogram 40

Circulation

MARCH 30, 2025

There was heterogeneity in cultural beliefs regarding heart transplantation, but the majority felt that it was acceptable if needed. Most patients felt that Traditional Medicine was important for their cardiovascular health and desired more of its integration into Western treatment.

Heart Failure 40

Heart Failure Health Disparities Heart Transplant Transplant 40

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2025

For patients who are candidates for renal transplantation (RT), major surgeries such as coronary artery bypass grafting (CABG) are associated with cardiac complications as well as higher rates of post-operative complications, including the need for large amounts of blood transfusion, worsening kidney function, infection, and graft rejection.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Transplant Cardiovascular Disease Pulmonary 52

Science Daily - Stroke

MARCH 10, 2025

The discovery could lead to more effective bone marrow transplants and gene therapies. A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study.

Transplant 52

Transplant 52

Circulation: Heart Failure

JULY 2, 2025

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Circulation 40

The New England Journal of Medicine

MAY 14, 2025

Despite vigorous efforts to expand the transplantation of organs from deceased and living donors, the gap between supply and demand persists. This lack of available organs has become a major factor in limiting the lifesaving potential of organ transplantation.

Transplant 41

Transplant 41

DAIC

JULY 9, 2025

Vaccination of pregnant women and other vulnerable patient groups, such as those with congenital heart disease and heart transplantation, is considered. Then follows advice on which vaccines should be given to patients with cardiovascular diseases and how often.

Congenital Heart Disease 52

Congenital Heart Disease Heart Failure Coronary Artery Disease Heart Transplant 52

Journal of Clinical Investigation - Cardiology

MAY 1, 2025

Umbilical cord blood (UCB) plays substantial roles in hematopoietic stem cell (HSC) transplantation and regenerative medicine. UCB is usually cryopreserved for years before use. It remains unclear whether and how cryopreservation affects UCB function.

Transplant 59

Transplant 59

All About Cardiovascular System and Disorders

JULY 5, 2025

MOMENTUM 3 trial compared HeartMate 3 with HeartMate II, either as a bridge to transplantation or as a destination therapy in 1028 patients with advanced-stage heart failure. Heartmate II is an axial continuous-flow pump which requires thoracoabdominal placement [1].

Transplant 52

Transplant Heart Failure Outcomes Strokes 52

Science Daily - Stroke

MARCH 21, 2025

This finding is particularly relevant for stem cell transplants, applied for the treatment of e.g. leukemia. The results yielded a surprise: Even stem cells possess surface proteins that enable them to suppress the activation of inflammatory and immune responses in the body.

Transplant 52

Transplant Research 52

American College of Cardiology

JULY 19, 2025

In this week’s View, Dr. Eagle looks at predictors of high-grade atrioventricular block (AV) after transcatheter tricuspid valve replacement (TTVR).

Heart Transplant 40

Heart Transplant Tricuspid Transplant Article 40

HCPLive

MAY 18, 2025

New research sheds light on improved waitlist outcomes after new allocation guidelines for lung transplants prioritizing medical urgency were implemented.

Transplant 72

Transplant Outcomes Research 72

Journal of Clinical Investigation - Cardiology

JUNE 16, 2025

We find that loss of hemodynamic forces in heterotopically transplanted hearts or genetic deletion of KLF2/4 in cardiac valve endothelium confers valve cell proliferation and matrix deposition associated with valve thickening, findings also observed in mice expressing the mutant fibrillin-1 protein known to cause human MVD.

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Transplant 80

Frontiers in Cardiovascular Medicine

JULY 7, 2025

Until 2024, the keywords with the strongest citation bursts included mitophagy, transplantation, homeostasis, and myocardial ischemia-reperfusion. International Journal of Molecular Sciences was the most co-cited journal in this field.

Ischemia 52

Ischemia Research Transplant Article 52

European Journal of Heart Failure

JUNE 17, 2025

Short-term and long-term mechanical circulatory support and heart transplantation were available at a median of 1.1 (IQR Natriuretic peptide assessment was available at a median of 6.1 (IQR emergency departments and 8.2 (IQR hospitals per million people, respectively, whilst cardiac magnetic resonance was available at a median of 2.0 (IQR

Reimbursement 40

Reimbursement Heart Failure Heart Transplant Transplant 40

The New England Journal of Medicine

JULY 11, 2025

Jacqui’s heart transplant gives her a new lease on life, but when the Covid pandemic arrives, the boundaries of an immunocompromised life in a hostile political climate become painfully clear.

Heart Transplant 55

Heart Transplant Transplant 55

DAIC

MAY 27, 2025

PhD, American Heart Association volunteer, professor of medicine at Cedars-Sinai and director of education, heart failure and transplantation at Smidt Heart Institute. Too many people remain unaware of or disconnected from lifesaving cardiovascular clinical trials, said Michelle Kittleson, M.D.,

Cardiomyopathy 52

Cardiomyopathy Education Webinar Heart Failure 52

Frontiers in Cardiovascular Medicine

FEBRUARY 24, 2025

This gap is particularly significant for those with contraindications to heart replacement therapies (HRT), such as left ventricular assist device (LVAD) or heart transplant. For patients who cannot tolerate or only partially respond to GDMT, therapeutic options remain limited.

Heart Failure 52

Heart Failure Heart Transplant Pharmacology Transplant 52

American College of Cardiology

JULY 18, 2025

In this week’s View, Dr. Eagle looks at predictors of high-grade atrioventricular block (AV) after transcatheter tricuspid valve replacement (TTVR).

Heart Transplant 40

Heart Transplant Tricuspid Transplant Article 40

American College of Cardiology

JULY 18, 2025

In this week’s View, Dr. Eagle looks at predictors of high-grade atrioventricular block (AV) after transcatheter tricuspid valve replacement (TTVR).

Heart Transplant 40

Heart Transplant Tricuspid Transplant Article 40

Circulation

JUNE 24, 2025

Single-cell RNA sequencing, flow cytometry, and immunofluorescence staining were employed to analyze cell populations in remodeled arteries 2 and 4 weeks after transplantation. Additionally, we used VEGFR-3 inhibitors and lymph node dissection to suppress lymphatic vessel formation.

Transplant 45

Transplant Circulation Outcomes 45

DAIC

JULY 16, 2025

As a board-certified cardiothoracic surgeon, cardiovascular surgeon and transplant surgeon, Dr. Joseph Woo is a nationally recognized leader and educator in cardiac surgery innovation. “And, as the daughter of a cardiologist, I am honored to be the first OB-GYN appointed to the Board in the history of the Association.”

Cardiothoracic 52

Cardiothoracic COVID-19 Education Innovation 52

All About Cardiovascular System and Disorders

JULY 2, 2025

There was a large list of exclusion criteria like acute coronary syndrome within the past 4 weeks, coronary revascularization procedure planned within next 6 months, known liver disease, current or planned renal dialysis or transplantation. According to a TCTMD news item, ORION-4 is expected to be completed in 2026.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Cholesterol Myocardial Infarction Aneurysm 52

Circulation: Cardiovascular Interventions

JULY 14, 2025

The secondary outcome is transplant-free survival.RESULTS:Overall, 50 patients with a median age of 2.7 Transplant-free survival was 92% at 12 months.CONCLUSIONS:A multimodal pulmonary vein catheterization assessment determined angiographic and intravascular ultrasound findings to be the most predictive of 12-month pulmonary vein outcome.

Pulmonary 40

Pulmonary Stenosis Ultrasound Outcomes 40

DAIC

APRIL 22, 2025

HCM impacts one in 200 people worldwide and is a leading reason for heart transplantation. This can transform clinical practice because the approach provides meaningful information in a clinically pragmatic fashion to facilitate patient care.

Sudden Cardiac Death 59

Sudden Cardiac Death Electrocardiogram Hospital Heart Transplant 59

Frontiers in Cardiovascular Medicine

APRIL 28, 2025

With the development of mesenchymal stem cell (MSC) transplantation technology, increasing research has shown that stem cell therapy and exosomes derived from these cells hold promise for repairing damaged myocardium and improving cardiac function, becoming a hot topic in clinical treatment for HF.

Heart Failure 52

Heart Failure Pharmacology Transplant Cardiac Function 52

Dr. Smith's ECG Blog

JUNE 3, 2025

The interventionalist stated that a transplanted heart does not have coronary disease. We were aware that ST Elevation can be a result of the low flow state in cardiac arrest, and resolve with time, but we activated the cath lab. A chart review however, revealed the the patient had had an acute distal LAD occlusion one month prior.

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Transplant Heart Transplant Cardiac Arrest 52