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Cedars-Sinai Cardiologist Leads the American Society of Transplantation

DAIC

Jon Kobashigawa, MD, of the Smidt Heart Institute at Cedars-Sinai, is an expert in heart transplantation, heart failure, and other complex cardiac conditions. Kobashigawa will also represent the American Society of Transplantation in discussions with government agencies and policymakers about organ transplant legislation. “Dr.

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Pegcetacoplan Offers Potential Benefit in Post-Transplant C3G, IC-MPGN

HCPLive

The phase 2 NOBLE trial shows pegcetacoplan reduces disease activity in post-transplant C3G and IC-MPGN, with benefits persisting through the 40-week double-blind period.

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Normothermic perfusion system extends life of organs waiting for transplant

Science Daily - Heart Disease

In the United States, about 30-40% of donor hearts aren't considered for transplant due to inadequate function in the donor. This leads to a drop in the number of donated hearts that are available to be matched with someone who needs a heart transplant.

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Pulmonary transplant complications: a radiologic review

Journal of Cardiothoracic Surgery

Lung transplantation has become the definitive treatment for end stage respiratory disease. Numbers and survival rates have increased over the past decade, with transplant recipients living longer and with gre.

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Risk Factors for IgA Nephropathy Recurrence After Kidney Transplant

HCPLive

Younger age at the time of kidney transplantation, faster progression to end-stage renal disease, a history of kidney transplantation, and no induction therapy were associated with IgAN recurrence, which was linked to poorer graft survival.

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Study Details Impact of Pancreas Transplantation on Kidney Function

HCPLive

More than half of patients who received a pancreas transplant alone experienced >50% decline in eGFR, had eGFR < 30 mL/min/1.73 m2, and/or received a kidney transplant 10 years after their initial pancreas transplant.

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A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models

Journal of Clinical Investigation - Cardiology

Long-term organ transplant survival remains suboptimal, and life-long immunosuppression predisposes transplant recipients to an increased risk of infection, malignancy, and kidney toxicity. We showed selective and sustainable Treg expansion by mIL-2 in 2 murine models of skin transplantation.