American College of Cardiology

AUGUST 14, 2024

The following are key points to remember from a state-of-the-art review on optimizing management of stable angina.

Angina 49

Angina Article 49

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

Furthermore, we utilized mass spectrometry analysis, network pharmacology, and lipidomics to predict the potential mechanisms of FFDS in the treatment of SCHD.ResultsFollowing treatment, FFDS demonstrated significant improvements in serum triglyceride levels (P=0.013) and a reduction in the frequency of angina episodes (P=0.021).

Heart Disease 52

Heart Disease Angina Cholesterol Pharmacology 52

Frontiers in Cardiovascular Medicine

JULY 5, 2024

BackgroundVasospastic angina usually presents with intermittent episodes of chest pain. The patient was started on calcium channel blocker therapy with resolution of symptoms.ConclusionPhantom odor perception has been rarely reported as an angina-equivalent symptom.

Angina 52

Angina Chest Pain Coronary Artery Disease Exercise 52

Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2024

Background Tongxinluo capsule (TXLC) is a common drug for treating angina pectoris of coronary heart disease (CHD). In recent years, many systematic reviews (SRs) and meta-analyses (MAs) have reported the efficacy and safety of TXLC for improving angina symptoms in patients with CHD.

Angina 64

Angina Heart Disease Electrocardiogram Cardiac Function 64

American College of Cardiology

DECEMBER 21, 2023

The goal of the ORBITA-2 trial was to assess the efficacy of percutaneous coronary intervention (PCI) compared with a sham placebo procedure for angina relief among patients with stable angina who were not on background antianginal medication.

Angina 56

Angina Angioplasty Article 56

Frontiers in Cardiovascular Medicine

JANUARY 22, 2024

However, there is a notable absence of data regarding patients with short-term myocardial ischemia, such as those experiencing unstable angina (UA). Following vascular recanalization therapy and regular medication treatment, the patient remained free of angina recurrence. The results demonstrated tracer-specific uptake (SUVmax = 4.6)

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Angina Ischemia Myocardial Infarction Electrocardiogram 69

NEJM Journal Watch - Cardiology

JANUARY 22, 2025

The coronary sinus reducer, approved in Europe, appears to improve angina and quality of life in patients with CMD or refractory angina.

Angina 45

Angina Quality of Life 45

Open Heart

JANUARY 12, 2023

It causes stable angina to ACS. Diltiazem was found to decrease angina and increase quality of life until 12th week of treatment; however, some adverse effects include atrioventricular block and recurrent angina up till 4th week were found. Nevertheless, several CCBs adverse effects are harmful for these patients.

Angina 52

Angina Quality of Life Article Outcomes 52

Dr. S. Venkatesan MD

SEPTEMBER 23, 2024

After a series of experiments in animals and peripheral vessels, he proved with a single patient N-1 study that effectively treated refractory LAD angina in a 38-year-old man in 1977. No one has questioned the efficacy of PCI for true angina with a critical lesion. Within a span of five to ten years, the concept spread globally.

Angina 52

Angina Academic Stenosis Article 52

Med Page Today

APRIL 8, 2024

(MedPage Today) -- ATLANTA -- For people with stable coronary artery disease and refractory angina, a coronary sinus reducer (CSR) implant showed a symptom alleviation benefit in the small placebo-controlled ORBITA-COSMIC trial. The number of.

Angina 52

Angina Coronary Artery Disease 52

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Background Refractory angina (RA) is a chronic condition characterized by the presence of debilitating angina symptoms due to established reversible ischemia in the presence of obstructive coronary artery disease (CAD).

Angina 64

Angina Quality of Life Coronary Artery Disease Ischemia 64

Open Heart

OCTOBER 17, 2024

Background Despite tremendous therapeutic advancements, a significant proportion of coronary artery disease patients suffer from refractory angina pectoris, that is, quality-of-life-compromising angina that is non-manageable with established pharmacological and interventional treatment options.

Angina 52

Angina Quality of Life Coronary Artery Disease Pharmacology 52

American College of Cardiology

JUNE 6, 2024

The ORBITA-2 (Objective Randomized Blinded Investigation With Optimal Medical Therapy of Angioplasty in Stable Angina) trial data demonstrate that, in patients with stable angina and ischemia producing coronary stenoses.

Angina 49

Angina Angioplasty Ischemia Article 49

DAIC

MARCH 11, 2024

a med tech company dedicated to helping patients with persistent ischemic heart disease, has announced the treatment of the first patient with the A-FLUX Reducer System, a treatment for patients with angina or chest pain. Angina is often caused by reduced blood flow to the heart. VahatiCor, Inc.,

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Angina Innovation Heart Disease Chest Pain 59

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

Ischemia with no obstructive coronary arteries (INOCA) is an increasingly recognized condition in patients presenting with angina and positive stress tests but without significant coronary artery stenosis.

Ischemia 52

Ischemia Angina Pharmacology Stenosis 52

American College of Cardiology

APRIL 8, 2024

A coronary sinus reducer (CSR) may lead to a significant reduction in the number of angina episodes in patients with chronic chest pain, but it was not superior to a placebo device for improving myocardial blood flow, according to the results of the ORBITA-COSMIC study, presented during a Late-Breaking Clinical Trial session at ACC.24

Angina 52

Angina Chest Pain Article 52

Med Page Today

JANUARY 8, 2024

(MedPage Today) -- Exercise electrocardiographic (ECG) stress tests appeared to reliably indicate that some patients with angina with nonobstructive coronary arteries (ANOCA) actually had coronary microvascular dysfunction (CMD), preliminary evidence.

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Exercise Angina 114

NEJM Journal Watch - Cardiology

APRIL 10, 2024

In a randomized, controlled trial, the device reduced daily angina but not myocardial ischemia in patients with refractory angina.

Angina 45

Angina Ischemia 45

Open Heart

APRIL 4, 2022

Objective Given recent data on published diagnostic accuracies, this study sought to determine the most cost-effective diagnostic strategy for detection of significant coronary artery disease (CAD) in stable angina patients using invasive coronary angiography (ICA) and fractional flow reserve (FFR) as the reference standard.

Angina 52

Angina Coronary Artery Disease 52

Med Page Today

MAY 3, 2024

(MedPage Today) -- LONG BEACH, Calif. -- A gene therapy for therapeutic angiogenesis showed promise for people with angina who had already exhausted their options for medical therapy and coronary revascularization, according to the single-arm.

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Angina 110

ECG Cases

JUNE 4, 2019

The post EM Quick Hits 5 Ludwig’s Angina, Transient Monocular Vision Loss, D-dimer for PE Workup in Pregnancy, Pediatric Nasal Foreign Bodies, Trimethoprim Drug Interactions, Airway Management in Cardiac Arrest appeared first on Emergency Medicine Cases.

Cardiac Arrest 52

Cardiac Arrest Angina Pediatrics Embolism 52

Frontiers in Cardiovascular Medicine

JANUARY 18, 2024

Aim Patients with unstable angina pectoris (UAP) usually present anxiety or depression during percutaneous coronary intervention (PCI). This study sought to investigate the instant and short-term effects of acupuncture for anxiety and depression in UAP patients with PCI.

Angina 64

Angina 64

DAIC

MAY 2, 2024

Results from the open label roll-in cohort of patients having chronic myocardial ischemia with refractory angina showed an average increase in exercise tolerance of 107 seconds and an average of 82% reduction in angina episodes at the primary six-month follow-up endpoint compared to before receiving the study treatment.

Ischemia 95

Ischemia Angina Heart Failure Outcomes 95

The New England Journal of Medicine

NOVEMBER 10, 2023

In a randomized trial of PCI in patients with stable angina who were receiving little or no antianginal medication and had documented ischemia, PCI resulted in a better health status with respect to angina than placebo at 12 weeks.

Angina 40

Angina Document Ischemia 40

Circulation

NOVEMBER 11, 2024

Approximately half of patients with CAD initially present with angina pectoris. The primary outcome was the Seattle Angina Questionnaire summary score (SAQ-SS) changes from baseline to 12 months. The primary outcome was the Seattle Angina Questionnaire summary score (SAQ-SS) changes from baseline to 12 months.

Angina 40

Angina Outcomes Quality of Life Cardiovascular Disease 40

Dr. Smith's ECG Blog

FEBRUARY 14, 2024

On occasion, unstable angina can present with reversible T-wave inversion during pain. Unstable angina in the era of hs trop still exists. I know of no data on unstable angina/30-day adverse events/acute MI after 2 serial undetectable trops. Unstable angina would be exceedingly rare in such a situation, but still possible.

Chest Pain 113

Chest Pain Angina Ischemia Outcomes 113

Frontiers in Cardiovascular Medicine

JANUARY 8, 2025

BackgroundPainful left bundle branch block (LBBB) syndrome is an uncommon disease that is defined as intermittent episodes of angina associated with simultaneous LBBB changes on an electrocardiogram (ECG) with the absence of flow-limiting coronary artery disease or ischemia on functional testing.

Chest Pain 52

Chest Pain Angina Coronary Artery Disease Blood Pressure 52

The American Journal of Cardiology

DECEMBER 13, 2023

Publication date: 15 January 2024 Source: The American Journal of Cardiology, Volume 211 Author(s): Namrita D. Ashokprabhu, Jessie Fox, Timothy D. Henry, Christian W. Schmidt, Darlene Tierney, Julie Gallatin, Yulith Roca Alvarez, Lauren Thompson, Michelle Hamstra, Sachin A. Shah, Odayme Quesada

Coronary Artery Disease 75

Coronary Artery Disease Angina 75

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2024

CVD included stroke, congestive heart failure, coronary heart disease, and angina. Asthma also increased the prevalence of angina in females, non-Hispanic Blacks, participants aged 4559 years old, with a BMI30.00kg/m2, and with a PIR<1.00.

Cardiovascular Disease 52

Cardiovascular Disease Heart Failure Angina BMI 52

Coronary Artery Disease Journal

OCTOBER 30, 2024

Refractory angina affects patients quality of life around the world. We aimed to investigate the efficacy and safety of CSR for refractory angina. However, there was no significant difference between CSR and the control group in double products, all Seattle Angina Questionnaire domains, and safety outcomes.

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Angina Quality of Life Exercise Outcomes 40

Science Daily - Heart Disease

SEPTEMBER 12, 2023

An advanced CT test can identify individuals with stable angina at a reduced risk of three-year adverse outcomes despite their having a high coronary artery calcium score, according to a new study.

Angina 40

Angina Outcomes 40

Circulation

OCTOBER 5, 2023

BACKGROUND:We investigated the usefulness of invasive coronary function testing to diagnose the cause of angina in patients with no obstructive coronary arteries.METHODS:Outpatients referred for coronary computed tomography angiography in 3 hospitals in the United Kingdom were prospectively screened. Circulation, Ahead of Print. versus 50.9%,P&lt;0.001).At

Angina 40

Angina Coronary Artery Disease Circulation Hospital 40

American College of Cardiology

MAY 20, 2024

The closer the similarity between patient-reported and medically induced angina symptoms, the more likely these symptoms will be improved following PCI, according to ORBITA-STAR, an n-of-1 placebo-controlled study presented at EuroPCR 2024.

Angina 40

Angina Article 40

Nature Reviews - Cardiology

APRIL 24, 2024

Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01033-x Findings from the ORBITA-COSMIC trial show that treatment of patients with stable coronary artery disease using a coronary sinus reducer improves angina symptoms but does not increase transmural myocardial perfusion.

Angina 40

Angina Coronary Artery Disease 40

Circulation: Cardiovascular Interventions

JANUARY 15, 2024

The present study aims to investigate whether coronary sinus narrowing improves the indexes of coronary microcirculatory function.METHODS:Patients with refractory angina who had a clinical indication for reducer implantation underwent invasive physiological assessments before and 4 months after the procedure.

Angina 40

Angina Coronary Artery Disease Physiology Cardiovascular Interventions 40

Cardiology Update

JANUARY 14, 2024

The perplexing landscape of angina with nonobstructive coronary arteries (ANOCA) encompasses diverse pathophysiological entities, including coronary microvascular disease (CMD), coronary artery spasm, and the enigmatic myocardial bridging (MB).

Exercise 119

Exercise Ischemia Angina Physiology 119

ECG Guru

MARCH 6, 2024

Ntg is presumably sublingual nitroglycerine used for angina. So, we can assume the patient was probably being treated for angina, heart failure, and hypertension. Lasix (furosemide) is a potassium – wasting diuretic. Capoten (captopril) is an ACE inhibitor. Procardia (nifedipine) is a calcium-channel blocker.

Tachycardia 98

Tachycardia ACE Inhibitor Angina Heart Failure 98