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Polypill Approved for Hypertension, Including as Initial Therapy

Med Page Today

(MedPage Today) -- The FDA approved a polypill containing telmisartan, amlodipine, and indapamide, known as Widaplik, for the treatment of hypertension in adults, including as initial treatment. This marks the first time that a triple combination.

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Backup Drug Gains Footing for Resistant Hypertension

Med Page Today

(MedPage Today) -- A diuretic was able to match spironolactone for blood pressure (BP) lowering in people with resistant hypertension, a small randomized trial showed. Home-measured systolic blood pressure (SBP) was similarly reduced at 12 weeks.

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Mass Screenings Alone Won't Control the U.S. Hypertension Problem

Med Page Today

(MedPage Today) -- Hypertension kills more people than any other condition. despite spending more than $4 trillion a year on healthcare, less than half of people with hypertension have their condition controlled even to below 140/90. In the U.S.,

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Blood pressure patterns during pregnancy predict later hypertension risk, study finds

Science Daily - Heart Disease

Women with blood pressure levels in a range considered clinically normal during pregnancy but no mid-pregnancy drop in blood pressure face an increased risk of developing hypertension in the five years after giving birth.

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New Study to Examine Hypercortisolism in Resistant Hypertension

DAIC

will establish the prevalence of endogenous hypercortisolism in patients with resistant hypertension. Resistant hypertension is defined by the American Heart Association as elevated blood pressure despite the use of three or more antihypertensive medications in different classes, including a diuretic.

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Right ventricles road to recovery: remodelling after chronic thromboembolic pulmonary hypertension intervention

Heart BMJ

Right heart failure is the most common cause of mortality in patients with pulmonary arterial hypertension. 1 This includes chronic thromboembolic pulmonary hypertension (CTEPH), which through obstruction of the pulmonary arteries increases afterload on the right ventricle (RV), ultimately resulting in RV failure.

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Challenges in Managing Resistant Hypertension

HCPLive

A panelist discusses how spironolactone is typically the first fourth medication added for resistant hypertension but has limitations in patients with kidney disease or electrolyte issues, necessitating alternative strategies like renal denervation and highlighting the need for multiple treatment approaches to avoid polypharmacy-related adherence problems. (..)