Physiologically Speaking

MARCH 30, 2025

Learn how VO2 max integrates multiple physiological systems (lungs, heart, blood vessels, mitochondria, and more) and why it’s a stronger predictor of longevity than traditional risk factors like cholesterol or BMI. With compelling data, he reveals how boosting your VO2 max by just 3.5

Physiology 104

Physiology BMI Cholesterol Risk Factors 104

Frontiers in Cardiovascular Medicine

JUNE 26, 2025

Multivariate analysis revealed that BMI (p = 0.003), procedure type (p < 0.001), conversion to sternotomy (p < 0.001), technical challenges (p = 0.034) and total procedure time (p < 0.001) were associated with extended incision length. The median total incision length was 16.5

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft BMI Bicuspid/Mitral Obesity 52

HCPLive

JUNE 8, 2025

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SCAD 114

SCAD Outcomes Cerebrovascular Disease Heart Failure 114

Frontiers in Cardiovascular Medicine

MAY 22, 2025

Care in endocrinology (OR=0.40; 95% CI, 0.230.68), higher BMI (OR=0.92; 95% CI, 0.880.95, per BMI unit), and a higher recent estimated glomerular filtration (OR=0.98; 95% CI, 0.960.99, per eGFR unit) predicted GLP-1RA prescription. Care in cardiology (OR=4.78; 95% CI, 2.539.04) strongly predicted SGLT2i prescription.

Diabetes 52

Diabetes BMI Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

JUNE 18, 2025

This study aimed to systematically evaluate the association between body mass index (BMI) and cardiovascular metabolic multimorbidity (CMM). The meta-analysis revealed that when BMI was analyzed as a categorical variable, both overweight (pooled OR = 3.52, 95% CI: 1.23–10.05) 10.05) and obesity (pooled OR = 3.68, 95% CI: 2.60–5.20)

BMI 52

BMI Obesity Education Research 52

Frontiers in Cardiovascular Medicine

JUNE 30, 2025

Subgroup analyses were conducted based on BMI, hypertension, and TyG index.ResultsNon-HDL-C was significantly associated with higher ASCVD risk and elevated hs-CRP and resistin levels, while RC showed weaker, non-significant associations. ASCVD risk was assessed using the Framingham risk score.

Cholesterol 52

Cholesterol Diabetes BMI Outpatient 52

Dr. Paddy Barrett

NOVEMBER 15, 2024

A study of almost 10,000 adults with obesity (BMI >30) who were evaluated for all LE8 factors and followed for over 7 years can give us some insight 1. The Life Essential 8 also include excess weight, but the question is whether those with excess weight who get the remaining seven factors right can significantly decrease their risk.

Heart Disease 98

Heart Disease Obesity Blood Pressure Cholesterol 98

Frontiers in Cardiovascular Medicine

JUNE 25, 2025

The nomogram includes five predictors: age, BMI ≥ 25 kg/m2, triglycerides, low-density lipoprotein cholesterol, and Log N-terminal brain natriuretic peptide precursor. mm2 (141 patients), macrophages (127 patients), and FCT < 75 μm (64 patients). The LASSO regression model was used to screen variables and develop an HRP risk factor model.

Plaque 52

Plaque Risk Factors BMI Laboratory 52

Open Heart

JANUARY 20, 2025

As diet control and weight control are poor, which means treatment adherence is poor, the BMI will be uncontrolled as well and leads to uncontrolled BP. Conclusion Systolic and diastolic blood pressure, BMI, and the number of antihypertensive medications taken daily were the predicting factors for treatment adherence.

Hypertension 52

Hypertension Blood Pressure Education BMI 52

Frontiers in Cardiovascular Medicine

MAY 14, 2025

Subgroup analyses stratified by age, BMI, and comorbidities consistently supported these findings (all P<0.05).ConclusionLow Each one-unit increase in TWA-Hb was associated with a 0.93-, 0.76- and 0.71-fold fold decrease in the risk of 90-day, 6-month, and 1-year mortality, correspondingly.

Cardiogenic Shock 52

Cardiogenic Shock Myocardial Infarction BMI Heart Disease 52

Frontiers in Cardiovascular Medicine

NOVEMBER 11, 2024

The Pearson correlation test was used to detect the association between WWI and BMI. The independent relationship and consistency between WWI and hypertension were assessed through weighted multivariate regression.

Hypertension 52

Hypertension Blood Pressure BMI 52

Frontiers in Cardiovascular Medicine

MARCH 14, 2025

Clinical information, parameters from left ventricular myocardial work and traditional two - dimensional strain echocardiography were collected and analyzed.ResultsAfter LSG, significant reductions in body mass index (BMI), diastolic blood pressure (DBP) and weight were observed.

Obesity 52

Obesity Blood Pressure BMI Cardiac Function 52

Frontiers in Cardiovascular Medicine

JULY 18, 2025

Compared with the MI-CAD group, MINOCA patients had a significantly lower BMI (p < 0.05). Laboratory findings revealed that LDL-C, apolipoprotein A, hs-cTnI, and CK-MB levels were significantly lower in the MINOCA group compared to the MI-CAD group (p < 0.01).

Myocardial Infarction 52

Myocardial Infarction Laboratory Coronary Artery Disease BMI 52

European Journal of Heart Failure

JUNE 16, 2025

AUC, area under the curve; BMI, body mass index; CI, confidence interval; CVP, central venous pressure; HF, heart failure; LSM, liver stiffness measurement; LVEF, left ventricular ejection fraction. Liver stiffness measurement for central venous pressure assessment.

Heart Failure 40

Heart Failure BMI Research Article 40

CardiacWire

JANUARY 29, 2025

They also often had lower BMI (31.0 While these mortality risks might seem convincing, there are several caveats to keep in mind, including the significant differences in patient characteristics between mechanical and bioprosthetic recipients. Patients receiving bioprosthetic valves tended to be older (65.2 vs 71.8%) or prior PCI (6.7

BMI 80

BMI Aortic Hypertension Research 80

CardiacWire

APRIL 27, 2025

The benefits of the GLP-1 were even greater for patients with severe obesity (BMI >40). GLP-1 use led to a 13% reduction in AFib hospitalizations, cardioversions, and ablation procedures, during a median follow-up of three years.

AFIB 59

AFIB Obesity Ablation BMI 59

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

Diabetes, Red blood cell distribution width (RDW), and Triglyceride glucose-body mass index (TyG-BMI), as determined by Lasso regression and multivariate logistic regression.

Coronary Artery Disease 52

Coronary Artery Disease Heart Disease BMI Diabetes 52

Med Page Today

JULY 7, 2025

(MedPage Today) -- More adults would be diagnosed with obesity when using a framework recently outlined by the European Association for the Study of Obesity (EASO) that goes beyond body mass index (BMI) alone. The 2024 framework takes a more.

Obesity 119

Obesity BMI 119

DAIC

JULY 10, 2025

In this study, they were key to revealing how natural variations in heart orientation, shaped by factors such as body mass index (BMI), sex, and hypertension, can significantly influence ECG readings. The researchers proposed new, standardized definitions for both anatomical and electrical axes based on their alignment in 3D space.

Anatomy 90

Anatomy BMI Blood Pressure Research 90

Frontiers in Cardiovascular Medicine

JUNE 24, 2025

Conventional indicators of obesity, waist circumference, waist-to-hip ratio, body mass index (BMI), have limitations in differentiating between fat and muscle mass. Subgroup analyses indicated that the association was stronger in individuals aged <60 years, nonHispanic Whites, and those with BMI < 30 kg/m2.ConclusionsElevated

Cardiovascular Disease 52

Cardiovascular Disease BMI Cholesterol Obesity 52

Frontiers in Cardiovascular Medicine

MAY 21, 2025

However, the traditional femoral-iliac approach for TAVR was constrained by the patient's peripheral vasculature and low BMI. Additionally, the aortic valve area was reduced, with valve leaflets severely calcified, significantly compromising their mobility. The patient opted for TAVR procedure.

TAVR 52

TAVR Aortic valve BMI Aortic 52

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2025

Subgroup analyses were conducted based on age, gender, body mass index (BMI), left ventricular ejection fraction (LVEF), and culprit artery.ResultsA total of 308 patients were included in the analysis, with 212 in the training set and 96 in the validation set.

Myocardial Infarction 52

Myocardial Infarction STEMI Obesity BMI 52

HCPLive

JUNE 6, 2025

Patients were defined as obese if their BMI was ≥30 kg/m2. “Both tirzepatide and liraglutide have demonstrated cardiometabolic benefits, but their comparative cardiovascular outcomes in high-risk populations remain poorly characterized,” wrote Essien and colleagues. 7% compared to liraglutide’s 1.4% (both HR,479; 95% CI,394-.582,

Obesity 72

Obesity Diabetes Cerebrovascular Disease Atrial Fibrillation 72

Physiologically Speaking

JANUARY 24, 2025

Participants on the low-carb diet experienced significant reductions in body weight, BMI, and body fat percentage compared to those on the high-carb diet. kg/m² reduction in BMI, and decreased their body fat percentage by 1.9%. Over the six weeks, the low-carb group lost an average of 2.3 kg of body weight, saw a 0.7

Physiology 64

Physiology Diet Exercise BMI 64

Frontiers in Cardiovascular Medicine

JUNE 13, 2025

Dyslipidemia was more common in PLWH residing in South China, with baseline CD4 cell count over 500 cells/μl or with a BMI ≥ 24 kg/m2. Elevated triglycerides(TG) and reduced high-density lipoprotein cholesterol (HDL-C) were the most prevalent dyslipidemia, irrespective of ART experience.

BMI 52

BMI Cholesterol Article Risk Factors 52

HCPLive

JULY 2, 2025

Based on a 52-week study of 792 participants, benefits were consistent regardless of HbA1c, diabetes duration, BMI, or SGLT2 inhibitor use. mg (Ozempic) significantly improved walking ability, quality of life, and reduced disease progression risk by 54% in patients with type 2 diabetes and peripheral artery disease (PAD).

Diabetes 64

Diabetes Hypertension RN CME 64

Dr. Paddy Barrett

APRIL 4, 2025

List vital measurements—eg Weight, Height, BMI etc. Make a list of all your medications & allergies. Give a detailed background of your family history. Describe your Smoking & Alcohol history. Here is a sample proforma I ask patients to complete before their first visit.

Blood Pressure 108

Blood Pressure Exercise Heart Disease Cholesterol 108

Frontiers in Cardiovascular Medicine

JULY 10, 2025

Receiver operating characteristic (ROC) curve analysis compared TyG, WC, TyG-BMI, and TyG-WC in diagnosing HTH. Logistic regression and restricted cubic spline (RCS) models analyzed the TyG-WC index's association with HTH. An additive interaction analysis evaluated the synergistic effect of TyG and WC on HTH.

Hypertension 52

Hypertension BMI Biomarkers Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

APRIL 23, 2025

Most research has focused on obese individuals, with limited exploration in those with a normal body mass index (BMI).MethodThis MethodThis study analyzed 4,440 adults with normal BMI from NHANES 20032018.

BMI 52

BMI Outcomes Obesity Cholesterol 52

DAIC

JANUARY 8, 2025

Subjects will be at least 18 years old, with a BMI 27 kg/m 2 , and the trial will be conducted across approximately 40 sites. The key objective of this trial is to validate the hypothesis that lorundrostat both alleviates the severity of upper airway obstruction and reduces nocturnal hypertension.

Blood Pressure 52

Blood Pressure Hypertension Kidney Disease BMI 52

HCPLive

JUNE 21, 2025

to 73.0), median BMI of 28.7 Baseline assessment of disease information indicated 61% had a duration of diabetes of 10 years or longer, and 59% had a BMI of less than 30 kg/m². Conducted in 20 countries, the trial enrolled and randomized 792 patients in a 1:1 ratio to receive semaglutide or placebo for 52 weeks. kg/m² (IQR, 25.6

Diabetes 120

Diabetes Peripheral Arterial Disease Quality of Life Obesity 120

CardiacWire

JULY 16, 2025

It also appears effective regardless of baseline bodyweight and reduces CV death and HF events across all BMI groups. The drug also significantly improved KCCQ from baseline by an average of 1.62 points at 12 months. Main adverse reactions included hyperkalemia (9.7% placebo), hypotension (7.6% vs 4.7%), hyponatremia (1.9%

Kidney Disease 59

Kidney Disease BMI Heart Failure Diabetes 59

European Journal of Heart Failure

JUNE 26, 2025

BMI, body mass index; CI, confidence interval; HR, hazard ratio; PAWP, pulmonary artery wedge pressure. Clinical significance of unintentional weight loss in heart failure with preserved ejection fraction (HFpEF).

Preserved Ejection Fraction 45

Preserved Ejection Fraction Heart Failure Exercise Obesity 45

European Journal of Heart Failure

APRIL 13, 2025

BMI, body mass index; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide. The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status.

Preserved Ejection Fraction 40

Preserved Ejection Fraction Heart Failure Pulmonary Peripheral Arterial Disease 40

Frontiers in Cardiovascular Medicine

JANUARY 10, 2025

and the ROC analysis results showed that the discriminatory power of WWI for CHD was superior to that of body mass index (BMI) and WC. Additionally, RCS analysis indicated a linear relationship between WWI and CHD. Glycated hemoglobin (HbA1c) partially mediated the relationship between WWI and CHD.

Heart Disease 52

Heart Disease Blood Pressure BMI Obesity 52

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

This study aimed to investigate the association of plasma lipid concentrations with the prevalence of OSA among US adults, with an additional examination of the mediating effect of body mass index (BMI).MethodsThis Furthermore, we discovered an inverted U-shaped association between triglyceride and OSA (inflection point: 0.813mmol/L).

BMI 52

BMI Cholesterol Research 52

Frontiers in Cardiovascular Medicine

JUNE 12, 2025

To investigate the intricate link between the TyG index, BMI and CVD, researchers employed weighted multiple logistic regression, linear regression, restricted cubic spline (RCS) analysis, mediation analysis, and subgroup analysis.ResultsAmong the study population, 1,895 Americans and 1,798 Chinese were diagnosed with cardiovascular disease (CVD).

BMI 40

BMI Cardiovascular Disease Research 40