Differential aortic aneurysm formation provoked by chemogenetic oxidative stress
Journal of Clinical Investigation - Cardiology
MAY 1, 2025
Aortic aneurysms are potentially fatal focal enlargements of the aortic lumen; the disease burden is increasing as the human population ages. Pathological oxidative stress is implicated in the development of aortic aneurysms. Generation of H2O2 in the endothelium led to oxidative stress throughout the vascular wall.
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