Sat.Jul 20, 2024 - Fri.Jul 26, 2024

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Dementia Risk Drops With Shingrix Vaccine

Med Page Today

(MedPage Today) -- The recombinant shingles vaccine (Shingrix) was associated with a larger reduction in dementia than the live shingles vaccine (Zostavax), an analysis of more than 200,000 U.S. older adults showed. Over a 6-year follow-up period.

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What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

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Empowering Patients with Educational Resources for Kidney Disease, with Mike Spigler

HCPLive

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

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Brain-heart axis: Strokes change epigenetics of immune system

Science Daily - Heart Disease

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs -- such as the heart. Researchers have worked on the hypothesis that the high rate of comorbidities that develop after a stroke could have a common immunological cause. And they actually managed to find it: The origin of the dysfunctions in other parts of the body lies in the immunological memory of the blood-forming cells in bone marrow.

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Persistent Anxiety Tied to Future Dementia

Med Page Today

(MedPage Today) -- Persistent anxiety raised the risk of all-cause dementia in older adults, a longitudinal study showed. Both chronic anxiety (HR 2.80, 95% CI 1.35-5.72, P=0.01) and new-onset anxiety (HR 3.20, 95% CI 1.40-7.45, P=0.01) were tied.

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A prehospital ECG in a patient with chest pain. The paramedics tell me it is normal.

Dr. Smith's ECG Blog

I was working at triage when the medics brought this patient who is 65 yo and has had chest pain for 12 hours. They recorded a prehospital ECG at 2112 and said that it was “normal”. It had already been crumpled up and put in the waste basket. So I uncrumpled it: What do you think? You need to click on it to enlarge it to view it well I was suspicious for inferior and posterior OMI (Large T-wave in aVF, slight STE in lead III with inverted T-wave in aVL, and a slightly downsloping ST with negativ

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Texas Heart Institute implants artificial heart

Becker's Hospital Review - Cardiology

"Discover the groundbreaking success of the first-in-human implantation of the BiVACOR Total Artificial Heart by the Texas Heart Institute, offering hope for he

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Nasal Sprays for Respiratory Infections; Paxlovid in COVID Prevention

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

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PVCs and their relationship to P waves, some examples

ECG Guru

In order to differentiate supraventricular extrasystoles/tachycardias with aberrant conduction from ventricular extrasystoles/tachycardias, the search for P waves is often very important. Here are some examples of how the P waves can be positioned around the ventricular extrasystoles.

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Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

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New study identifies two proteins that may contribute to stroke recurrence

Science Daily - Heart Disease

A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes. These proteins are known to activate inflammation, which plays a key role in the development of strokes and many chronic conditions and diseases.

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Increasing cardiac ketones may help heart failure in mouse study

American Heart News - Heart News

Research Highlights: In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy. Researchers hope this study may help to improve our.

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Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

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Hemophilia A Gene Therapy Displays Superiority in Phase 3 AFFINE Trial

HCPLive

Giroctocogene fitelparvovec achieved primary and key secondary objectives of superiority compared to routine prophylaxis in hemophilia A treatment.

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Increasing Prediabetes remission for type 2 diabetes

Science Daily - Heart Disease

In mice with heart failure with preserved ejection fraction (HFpEF), increasing ketone supply to the heart allowed their hearts to utilize more ketones and produce more energy.

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SCCT Awards Best Original Science of 19th Annual Scientific Meeting

DAIC

mtaschetta-millane Tue, 07/23/2024 - 10:59 July 23, 2024 — The Society of Cardiovascular Computed Tomography (SCCT) announced its best original science award winners of the 19th Annual Scientific Meeting (SCCT2024) in Washington, DC. Prior to the conference, an independent panel of judges led by Marcus Chen, MD selected two winners for the 18th Annual Canon Young Investigator Awards (YIA) in cardiovascular CT, sponsored by an educational grant from Canon Medical Systems, Inc.

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Pay People, and They Will Go to Cardiac Rehab

Med Page Today

(MedPage Today) -- It might take giving people money directly for them to participate in cardiac rehabilitation, a randomized trial showed. Eligible patients in Vermont of lower socioeconomic status had cardiac rehab adherence rates shoot up if.

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Children with Cerebral Palsy Have More Anxiety Than Those Without this Disorder

HCPLive

A study found children and young adults with cerebral palsy have more anxiety and less depression than those with a chronic condition or who are typically developed.

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Physical activity improves early with customized text messages in patients with heart problems

Science Daily - Heart Disease

Personalized text messages effectively promoted increased physical activity for patients after significant heart events -- such as a heart attack or surgery -- but those effects later diminished. Researcher say the results show incredible promise for simple, low cost interventions delivered through mobile technology and their potential to help prevent secondary cardiovascular events in patients.

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Resuscitated from ventricular fibrillation. Should the cath lab be activated?

Dr. Smith's ECG Blog

This patient was witnessed by bystanders to collapse. They started CPR. EMS arrived and found him in Ventricular Fibrillation (VF). He was defibrillated into VT. He then underwent dual sequential defibrillation into asystole. After 1 mg of epinephrine they achieved ROSC. Total prehospital meds were epinephrine 1 mg x 3, amiodarone 300 mg and 100 mL of 8.4% sodium bicarbonate.

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The Case for Keto for Type 1 Diabetes with Andrew Koutnik, Ph.D.

Physiologically Speaking

Greetings! Today’s interview is with Andrew Koutnik, Ph.D. Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. Andrew is unique because he himself has type 1 diabetes.

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Gout Prevalence Estimated to Increase More Than 70% by 2050

HCPLive

The number of prevalent gout cases is projected to reach 95.8 million by 2050, with population growth cited as the largest contributor.

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FibriCheck Enters US Market with FDA Clearance

DAIC

mtaschetta-millane Wed, 07/24/2024 - 11:34 July 24, 2024 — After a rigorous investigation procedure by the Food and Drug Administration, FibriCheck is now FDA-cleared (K232804). This is an important milestone which supports FibriCheck’s further development in the U.S. market. The FDA-clearance also allows FibriCheck to improve current U.S. care pathways and to provide millions of Americans with the ability to just use their smartphone to obtain easy and accurate heart rhythm measurements.

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How does the brain respond to sleep apnea?

Science Daily - Heart Disease

Nearly 40 million adults in the U.S. have sleep apnea, and more than 30 million of them use a continuous positive airway pressure (CPAP) machine while sleeping. However, the machines tend to be expensive, clunky and uncomfortable -- resulting in many users giving up on using them. High blood pressure is often linked with sleep apnea because the brain works harder to regulate blood flow and breathing during sleep.

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Dapagliflozin and Right Ventricular Pulmonary Vasculature in HFpEF

JAMA Cardiology

This randomized clinical trial investigates the effect of dapagliflozin on right ventricular performance and vascular load during exertion in heart failure with preserved ejection fraction (HFpEF).

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FDA Accepts sNDA for Furosemide (Furoscix) in Chronic Kidney Disease

HCPLive

The sNDA for furosemide seeks to expand the indication to include the treatment of edema due to fluid overload in patients with CKD, with a PDUFA date of March 6, 2025.

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New research explores alcohol’s impact on the heart

American Heart News - Heart News

Research Highlights: Two new, basic research studies in rodents (mice and rats) analyzed the impacts that alcohol may have on the heart. In a mouse study, abnormal heart rhythms that can occur after a pattern of repeated simulation of binge drinking.

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Method enables fast, accurate estimates of cardiovascular state to inform blood pressure management

Science Daily - Heart Disease

A new mathematical method, validated with experimental animal data, provides a fast, reliable and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.

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Physiology Friday #228: Identifying Sleep Patterns that Influence Chronic Disease Risk

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. ICYMI: On Wednesday, I published my video interview with Dr. Andrew Koutnik. We talk about the ketogenic diet as a metabolic therapy for type 1 diabetes. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post!

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Physical Activity Linked to Reducing Depression Symptoms, Mediated by Pain

HCPLive

A study found the association between physical activity engagement and reduction in depression symptoms is moderated by pain.

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International Atherosclerosis Society Issues New White Paper Underscoring Inflammation's Role, Offering Key Recommendations

DAIC

The International Atherosclerosis Society (IAS) has released a clinical proceedings white paper outlining the role of inflammation in atherosclerosis and the importance of early intervention. The paper is part of IAS’ Clinical Proceedings, a white paper series, which offers informational resources intended to raise awareness and address unmet needs in atherosclerosis.

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Artificial blood vessels could improve heart bypass outcomes

Science Daily - Heart Disease

3D-printed blood vessels, which closely mimic the properties of human veins, could transform the treatment of cardiovascular diseases. Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.

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Intermountain opens new cardiac rehab clinic

Becker's Hospital Review - Cardiology

"Discover Intermountain Health's new cardiac rehab clinic at Riverton Hospital, bringing cutting-edge care closer to home for patients in Salt Lake City's south

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Defining Iron Deficiency

HCPLive

The panel provides a broad overview of the treatment of patients with iron deficiency, highlighting diagnostic practices.

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Doctors who know the impact of pregnancy complications on our cardiac risk

Heart Sisters

I didn't even know until after my heart attack that a preeclampsia diagnosis during my first pregnancy meant I was at 2-3 times higher risk for heart disease.

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Renowned Cardiologist Behind ‘Go Red for Women’ Campaign, Nieca Goldberg, MD, Announces Return to Practice at NYU Langone

DAIC

Nieca Goldberg, MD, board-certified cardiologist, educator, author, and advocate for women’s health, has announced she is returning to practice at NYU Langone Health, where she also serves as Clinical Associate Professor, Department of Medicine at NYU Grossman School of Medicine. Image courtesy: Finn Partners christine.book Mon, 07/22/2024 - 11:36 July 22, 2024 — Nieca Goldberg, MD , a board-certified cardiologist, educator, author, and advocate for women’s health, has announced that she is retu