Sat.May 10, 2025 - Fri.May 16, 2025

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Seek medical advice before attempting water-only fasting diets, experts warn

Science Daily - Heart Disease

Experts are urging people, especially those with existing heart or vascular conditions, to seek medical advice before attempting to lose weight using water-only fasting diets.

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Maternal Avocado Intake Tied to 44% Drop in Infant Food Allergy Risk

HCPLive

New research reveals that maternal avocado consumption during pregnancy significantly reduces the risk of infant food allergies.

Research 101
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Albuminuria and cardiovascular outcomes in early-stage chronic kidney disease

Heart BMJ

Chronic kidney disease (CKD) represents a significant global health priority, affecting approximately 844 million adults (10% of the world population). 1 Beyond its implication for kidney health, CKD is inherently linked to cardiovascular disease (CVD), which is the leading cause of morbidity and mortality in this population. 2 The interplay between CKD and CVD is well documented, with mechanisms including shared risk factors, metabolic disturbances and systemic inflammation. 2 Albuminuria, a ma

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Could a mini-stroke leave lasting fatigue?

Science Daily - Stroke

A transient ischemic attack, also known as a mini-stroke, is typically defined as a temporary blockage of blood flow to the brain that causes symptoms that go away within a day, but a new study finds that people who have this type of stroke may also have prolonged fatigue lasting up to one year.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Backup Drug Gains Footing for Resistant Hypertension

Med Page Today

(MedPage Today) -- A diuretic was able to match spironolactone for blood pressure (BP) lowering in people with resistant hypertension, a small randomized trial showed. Home-measured systolic blood pressure (SBP) was similarly reduced at 12 weeks.

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Study Finds Underuse of Allergy Treatments in Teens with Pollen Allergic Rhinitis

HCPLive

A study shows that many children with pollen allergies face ongoing symptoms into adulthood, highlighting the need for better management.

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Diagnostic value and clinical impact of cardiac magnetic resonance imaging in patients after sudden cardiac arrest: a retrospective study

Open Heart

Introduction Cardiac MRI (CMRI) is an important investigation in cases of unclear cause of sudden cardiac arrest (SCA). It demonstrates diagnostic utility in assessing reversibility and tissue scar burden and ultimately aids in further treatment planning. Methods A retrospective analysis of all adult patients referred for CMRI after SCA between 2007 and 2022 by local intensive care units in our institution was performed.

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Age-specific prognosis of acute and steady minor elevations in cardiac troponin among non-acute myocardial infarction inpatients: a large real-world cohort study

Heart BMJ

Background The upper reference limit of normal (ULN) of cardiac troponin (cTn) for older adults can be higher than for young adults, while the same ULN is used for both older and young adults in the current clinical practice. Methods In this multicentre longitudinal cohort study, non-acute myocardial infarction (non-AMI) inpatients with at least two cTn concentrations hospitalised between 2013 and 2022 in the Tianjin Health and Medical Data Platform were included.

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IgE, Skin Prick Test Show Limited Diagnostic Utility for Pediatric Shrimp Allergy

HCPLive

Skin prick test showed limited symptom correlation and shrimp-specific IgE demonstrated greater diagnostic value than tropomyosin-specific IgE.

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Association between time-varying weighted hemoglobin and all-cause mortality in patients with acute myocardial infarction-related cardiogenic shock

Frontiers in Cardiovascular Medicine

Background and aimsAnemia has been implicated in prognosis across ischemic heart diseases. This study aimed to investigate the association between time-weighted average hemoglobin (TWA-Hb) and all-cause mortality in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS).Methods and resultsWe conducted a retrospective analysis of 765 patients diagnosed with AMI-CS using data from the MIMIC-IV database (20082019).

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Women with infertility history at greater risk of cardiovascular disease after assisted conception

Medical Xpress - Cardiology

Women who experience infertility are more likely to develop heart and blood vessel conditions later in life, with younger women and those who undergo fertility treatments at a greater risk. The findings, presented at the first Joint Congress between the European Society of Pediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE), highlight the importance of considering a woman's reproductive history when assessing her long-term heart health.

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Prognostic impact of albuminuria in early-stage chronic kidney disease on cardiovascular outcomes: a cohort study

Heart BMJ

Background The impact of early-stage chronic kidney disease (CKD) on cardiovascular outcomes, particularly when albuminuria is present, remains unclear. This study examined the associations between early CKD (stages 1 and 2) with and without albuminuria and the incidence of major adverse cardiovascular events (MACEs), heart failure (HF) and all-cause mortality.

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Iron Deficiency Anemia Significantly Increases Ischemic Stroke Risk in Young Adults

HCPLive

A study reveals a significant link between iron deficiency anemia and increased ischemic stroke risk in young adults, highlighting urgent screening needs.

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Exploring the role of the atherogenic index of plasma as a mediator between body roundness Index and cardiovascular events in older adults: a NHANES-based study

Frontiers in Cardiovascular Medicine

BackgroundThe rising incidence of cardiovascular diseases (CVD) in the elderly highlights the need for effective preventive strategies. Recent studies suggest that obesity, through metabolic factors, contributes to the development of CVD. This study aims to explore how body roundness index (BRI) levels affect the occurrence of CVD using data from the National Health and Nutrition Examination Survey (NHANES) (20032016), to better understand the role of obesity in CVD prevention and management.Met

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Cardiovascular Magnetic Resonance for Quantification of Mitral Regurgitation

American College of Cardiology

Assessment of mitral regurgitation (MR) has traditionally been performed with echocardiography. However, echocardiography has known limitations including the lack of a single reliable parameter of severity, high inter- and intraobserver variability, and discordance between echocardiographic parameters in a given patient.

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Road to Boston Training Log | Race Recap!

Physiologically Speaking

Thank you all for following this journey through to the end. It still blows my mind that tens of thousands of people (some strangers, some friends) returned weekly to read about my training for the Boston Marathon. I sincerely hope something I shared has helped you train smarter or harder—whether for Boston or otherwise. That’s really the goal!

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Study Highlights Facts About Anaphylaxis Induced by Goat's and Sheep's Milk

HCPLive

These data compare the characteristics and trends of anaphylaxis caused by goat and sheeps milk allergies with those of cows milk and peanut allergy.

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OCT-based diagnosis, management, and predictors of recurrent stent failure: a cohort study

Frontiers in Cardiovascular Medicine

BackgroundStent failure (SF) is a complication of percutaneous coronary intervention (PCI).ObjectivesThis study aimed to assess the relationship of the optical coherence tomography (OCT) determined cause of SF with time since stent implantation, treatment, and outcome.MethodsThis retrospective study included patients who underwent an OCT evaluation for SF from January 2013 to July 2023.

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Novel OCT-FLIm Imaging Feasible, Safe For Identifying High-Risk Plaques in CAD

American College of Cardiology

A novel multitargeted intracoronary imaging technique that combines fluorescence lifetime imaging (FLIm) with optical coherence tomography (OCT) is a clinically feasible and safe diagnostic tool for identifying high-risk plaques in patients with coronary artery disease (CAD).

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Dr. Adam Castano and Dr. C. Michael Gibson discuss: ACT-EARLY, a Phase 3 Study – Clinical Trial Results

Clinical Trial Results

Disclosures: Sponsored by BridgeBio Pharma, Inc

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Bedtime vs Morning Dosing of Blood Pressure Meds Shows No Benefit in Frail Elderly

HCPLive

New findings reveal that timing of antihypertensive medicationbedtime vs. morningshows no significant impact on health outcomes for frail older adults.

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Case Report: a 28-year-old female with anomalous origin of the left coronary artery from the pulmonary artery syndrome presented as atrial fibrillation and pulmonary hypertension

Frontiers in Cardiovascular Medicine

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) typically manifests in the first weeks of life. We report a 28-year-old woman with atrial fibrillation and pulmonary hypertension which were later found to be associated with ALCAPA syndrome. Despite a history free of traditional cardiovascular risk factors, her symptoms included exercise intolerance, palpitations, and an ischemic stroke.

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Ultra-Processed Foods May Be Associated With Adverse Health Outcomes

American College of Cardiology

Consumption of ultra-processed foods, such as sugar-sweetened beverages, breads, potato chips and packaged cookies, may be associated with adverse health outcomes, including hypertension, cancer, digestive diseases and adverse cardiovascular events.

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British Cardiovascular Society Annual Conference, 2025: message from Vice President Dr Shouvik Haldar and Chair of the Programme Committee, Professor Andrew Clark

Heart BMJ

On behalf of the President of the British Cardiovascular Society (BCS), Board, Executive and Programme Committee, we look forward to welcoming you at the BCS Annual Conference, 2–4 June 2025, held at Manchester Central. The theme of the conference this year is ‘The Risk Business’ We appreciate that this is a broad theme that could mean many things to many people, and indeed it gives us the bandwidth to discuss many aspects of cardiology from that perspective.

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Study Identifies Association Between Psoriasis, Sleep Disorders in National Cohort

HCPLive

In this analysis, investigators looked at the extent to which psoriasis severity correlates with patients risk of developing sleep disorders.

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A higher preoperative total protein to albumin ratio independently predicted more severe postoperative acute kidney injury in patients with acute type A aortic dissection: a retrospective cohort study of 224 cases

Frontiers in Cardiovascular Medicine

ObjectivesIn this retrospective study, we investigated the incidence of postoperative acute kidney injury (AKI) and determined the predictors associated with AKI in patients underwent surgeries for acute type A aortic dissection (ATAAD).MethodsWe enrolled patients diagnosed with ATAAD and received operation. AKI was defined based on the Kidney Disease: Improving Global Outcomes criteria.

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Revisiting the Open Vein Hypothesis to Reduce the Postthrombotic Syndrome: Implications for Multidisciplinary Care and Research: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. The open vein hypothesis postulates that early thrombus clearance and restoration of venous blood flow may prevent postthrombotic syndrome after proximal deep vein thrombosis. Since its proposal several decades ago, new insights from basic and clinical studies have motivated a re-evaluation and refinement of this hypothesis.

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Can Lamin Dilated Cardiomyopathy Be Identified Earlier?

American College of Cardiology

Cardiovascular magnetic resonance (CMR) imaging was able to detect longer myocardial T2, higher extracellular volume (ECV) fraction and worse myocardial dynamics, including impaired strain, before significant decline in left ventricular (LV) systolic function in carriers of LMNA (Lamin) dilated cardiomyopathy (DCM).

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Type 1 Diabetes Diagnosed in Adulthood Heightens Cardiovascular Risk

HCPLive

Adult-onset T1D significantly raises cardiovascular disease and mortality risks, highlighting the need for improved management and prevention strategies.

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Pfizer Confirms: Leading JAK Inhibitor Often Comes With Weight Gain

Med Page Today

(MedPage Today) -- Patients taking tofacitinib (Xeljanz) in the drug's late-stage and post-marketing studies were more likely than those on placebo to gain weight and body mass index (BMI) points, pooled data from more than 5,000 rheumatoid arthritis.

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Xenotransplantation — Long Awaited, Much Learned, Much More to Be Learned

The New England Journal of Medicine

Despite vigorous efforts to expand the transplantation of organs from deceased and living donors, the gap between supply and demand persists. This lack of available organs has become a major factor in limiting the lifesaving potential of organ transplantation. Xenotransplantation, which has been hailed as the ultimate solution, seemed mirage-like.

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ACCEL Lite: Cardiac Arrest During Long-Distance Running Races: 2010-2023

American College of Cardiology

In this episode, Drs. Jonathan H. Kim and Aaron L. Baggish discussed the study findings, emphasizing the importance of continued vigilance and preparedness to further reduce the risk of fatal outcomes during endurance events.

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Understanding Hypertension: Epidemiology and Prevalence

HCPLive

A panelist discusses how hypertension, often called the silent killer, remains a widespread yet underdiagnosed and undertreated condition globally, contributing significantly to cardiovascular and kidney-related morbidity despite being largely preventable and manageable.

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Nonlinear Relationship Between Left Atrial Volume Measured by Computed Tomography and Recurrent Atrial Arrhythmias in Patients Undergoing Catheter Ablation for Atrial Fibrillation

Journal of Cardiovascular Electrophysiology

ABSTRACT Background Left atrial remodeling is commonly believed to contribute to the recurrence of atrial arrhythmias following catheter ablation for atrial fibrillation (AF). However, the relationship between left atrial volume (LAV) assessed via left atrial computed tomography (LACT) and AF recurrence remains insufficiently explored. Aim This study aimed to examine the association between LAV measured by LACT and the recurrence of AF.

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Effect of pulmonary artery pressure‐guided management on outcomes of patients with heart failure outside clinical trials: A systematic review and meta‐analysis of real‐world evidence with the CardioMEMS Heart Failure System

European Journal of Heart Failure

Meta-analysis on the main outcomes of pulmonary artery pressure (PAP)-guided management with the CardioMEMS Heart Failure (HF) System in patients with HF outside clinical trials. Effect measures are expressed as pooled means (95% CI), mean differences (95% CI), or pooled incidence rate ratios (95% CI), as appropriate. CI, confidence interval; DSRC, device and system-related complication; HFH, heart failure hospitalization; NYHA, New York Heart Association; VAS, visual analogue scale.

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Correction to: Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results from VALOR-HCM

Circulation

Circulation, Volume 151, Issue 19 , Page e1001-e1001, May 13, 2025.