American Heart News - Heart News
FEBRUARY 28, 2024
Research Highlights: An analysis of survey data for 430,000 adults in the U.S. found that using cannabis has a significant association with an increased risk of heart attack and stroke, independent of tobacco use, with higher odds among the adults.
Med Page Today
FEBRUARY 12, 2024
(MedPage Today) -- Blood protein profiles predicted future dementia in healthy adults, a large longitudinal study showed. Blood samples from over 50,000 people in the U.K. Biobank showed that four proteins -- glial fibrillary acidic protein.
American Heart News - Stroke News
FEBRUARY 1, 2024
Research Highlights: In a large population study conducted in Canada, the risk of dementia was nearly 3 times higher in the first year after a stroke, then fell to a 1.5-times increased risk by the 5-year mark and remained elevated 20 years later.
Journal of Clinical Investigation - Cardiology
FEBRUARY 1, 2024
While the poor prognosis of glioblastoma arises from the invasion of a subset of tumor cells, little is known of the metabolic alterations within these cells that fuel invasion. We integrated spatially addressable hydrogel biomaterial platforms, patient site–directed biopsies, and multiomics analyses to define metabolic drivers of invasive glioblastoma cells.
Cardiovascular Diabetology
FEBRUARY 9, 2024
Currently, the differentiation between type 1 diabetes (T1D) and type 2 diabetes (T2D) is not straightforward, and the features of both types of diabetes coexist in one subject. This situation triggered the ne.
Medical Xpress - Cardiology
FEBRUARY 15, 2024
More than 4,500 heart transplants were performed in the U.S. in 2023. While the lifesaving operation improves the quality of life and longevity for most recipients, organ rejection remains a risk, with acute rejection occurring in up to 32% of recipients within the first year.
American Heart News - Heart News
FEBRUARY 27, 2024
Research Highlights Closer proximity to and a higher number of ready-to-eat food outlets — particularly pubs, bars and fast-food restaurants — may be associated with a greater risk of developing heart failure, according to a study of half a million.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Dr. Smith's ECG Blog
FEBRUARY 22, 2024
Written by Pendell Meyers A woman in her 30s called EMS for acute symptoms including near-syncope, nausea, diaphoresis, and abdominal pain. EMS arrived and found her to appear altered, critically ill, and hypotensive. An ECG was performed: What do you think? Extremely wide complex monomorphic rhythm just over 100 bpm. The QRS is so wide and sinusoidal that the only real possibilities left are hyperkalemia or Na channel blockade.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
C1q/TNF-related protein 4 (CTRP4) is generally thought to be released extracellularly and plays a critical role in energy metabolism and protecting against sepsis. However, its physiological functions in autoimmune diseases have not been thoroughly explored. In this study, we demonstrate that Th17 cell–associated experimental autoimmune encephalomyelitis was greatly exacerbated in Ctrp4–/– mice compared with WT mice due to increased Th17 cell infiltration.
American Heart News - Stroke News
FEBRUARY 8, 2024
Research Highlights: An artificial intelligence (AI) system to help guide treatment decisions for stroke patients led to improved stroke care quality and fewer recurrent strokes, heart attacks and vascular death among stroke survivors three months.
Medical Xpress - Cardiology
FEBRUARY 23, 2024
A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis—the formation of blood clots—researchers report February 23 in the journal Cell Metabolism. The results also revealed that 2MBC is accumulated in individuals with COVID-19, potentially explaining why these patients are at increased risk of thrombosis.
American Heart News - Heart News
FEBRUARY 12, 2024
Embargoed until 4 a.m. CT/5 a.m. ET Monday, Feb. 12, 2024 DALLAS, Feb. 12, 2024 — Dramatic advances in the understanding and treatment of cardiovascular diseases have saved millions of lives in the 100 years since the founding in 1924 of the American.
Med Page Today
FEBRUARY 5, 2024
(MedPage Today) -- Cognitive function was better for older adults with healthy lifestyles even if they had Alzheimer's or other dementia-related pathologies, autopsy data showed. A 1-point increase in a healthy lifestyle score was associated with.
HCPLive
FEBRUARY 18, 2024
Results of a multivariate logistic regression analysis showed previous exposure to occupational noise was positively associated with both rheumatoid arthritis and osteoarthritis.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Skull development coincides with the onset of cerebrospinal fluid (CSF) circulation, brain-CSF perfusion, and meningeal lymphangiogenesis, processes essential for brain waste clearance. How these processes are affected by craniofacial disorders such as craniosynostosis are poorly understood. We report that raised intracranial pressure and diminished CSF flow in craniosynostosis mouse models associate with pathological changes to meningeal lymphatic vessels that affect their sprouting, expansion,
Physiologically Speaking
FEBRUARY 19, 2024
Endurance performance is determined by three primary variables which were proposed by Dr. Michael Joyner over 3 decades ago in a paper titled “Modeling optimal marathon performance on the basis of physiological factors.” These factors are the performance VO2, lactate threshold, and running economy. Performance VO2 is the average oxygen consumption an athlete has to sustain during an event, e.g., the marathon.
American Heart News - Stroke News
FEBRUARY 7, 2024
Research Highlights: Although giving blood thinners along with clot-busting medication may help in treating heart attacks, it did not improve 90-day outcomes in people with clot-caused strokes. Enrollment in a large clinical trial, which had been.
Science Daily - Stroke
FEBRUARY 9, 2024
A new study has found the immune system in the blood of Alzheimer's patients is epigenetically altered. That means the patients' behavior or environment has caused changes that affect the way their genes work. Many of these altered immune genes are the same ones that increase an individual's risk for Alzheimer's. Scientists now theorize the cause could be a previous viral infection, environmental pollutants or other lifestyle factors and behaviors.
Med Page Today
FEBRUARY 26, 2024
(MedPage Today) -- Lipoprotein(a), or Lp(a), at levels well below currently accepted risk thresholds correlated with increased cardiovascular risk in a large registry study, suggesting a wider patient pool that could benefit from future preventive.
HCPLive
FEBRUARY 29, 2024
Cancer patients with behavioral health disorders, such as substance abuse, eating disorders, and sleep disorders have a 7.76% increase in health care costs, a new study found.
Journal of Clinical Investigation - Cardiology
FEBRUARY 1, 2024
Synaptic plasticity is obstructed by pathogenic tau in the brain, representing a key mechanism that underlies memory loss in Alzheimer’s disease (AD) and related tauopathies. Here, we found that reduced levels of the memory-associated protein KIdney/BRAin (KIBRA) in the brain and increased KIBRA protein levels in cerebrospinal fluid are associated with cognitive impairment and pathological tau levels in disease.
Cardiovascular Diabetology
FEBRUARY 12, 2024
Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a.
American Heart News - Stroke News
FEBRUARY 6, 2024
Embargoed until 8 a.m. MT/10 a.m. ET, Tuesday, Feb. 6, 2024 PHOENIX, Feb. 6, 2024 – Eleven scientists leading the way in stroke research will be recognized during the American Stroke Association’s International Stroke Conference 2024 for their.
Dr. Smith's ECG Blog
FEBRUARY 2, 2024
Written by Pendell Meyers First try to interpret this ECG with no clinical context: The ECG shows an irregularly irregular rhythm, therefore almost certainly atrial fibrillation. After an initially narrow QRS, there is a very large abnormal extra wave at the end of the QRS complex. These are Osborn waves usually associated with hypothermia. There is also large T wave inversion and long QT.
Med Page Today
FEBRUARY 19, 2024
(MedPage Today) -- Niacin metabolism was associated with incident major adverse cardiovascular events (MACE) and may be linked to the pathogenesis of heart disease via inflammatory pathways, researchers said. In a metabolomics study of stable.
HCPLive
FEBRUARY 20, 2024
A new study found crisis response planning for PTSD among military veterans had lower onset of suicidal ideation than veterans with self-guided safety planning.
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Blood vessels are continually exposed to circulating lipids, and elevation of ApoB-containing lipoproteins causes atherosclerosis. Lipoprotein metabolism is highly regulated by lipolysis, largely at the level of the capillary endothelium lining metabolically active tissues. How large blood vessels, the site of atherosclerotic vascular disease, regulate the flux of fatty acids (FAs) into triglyceride-rich (TG-rich) lipid droplets (LDs) is not known.
American Heart News - Heart News
FEBRUARY 5, 2024
Research Highlights: The weight loss medication tirzepatide significantly lowered the systolic blood pressure of nearly 500 adults who had obesity and took the medication for 36 weeks, or about eight months, in a subset of an international clinical.
Science Daily - Heart Disease
FEBRUARY 5, 2024
Scientists have found soundwaves from low-intensity focused ultrasound aimed at a place deep in the brain called the insula can reduce both the perception of pain and other effects of pain, such as heart rate changes.
Medical Xpress - Cardiology
FEBRUARY 2, 2024
As opposed to the sensory perception of the external world, interoception is the sensing of internal body signals, which informs the brain about the state of the body. Rhythmic bodily processes such as breathing, the heartbeat, or the pulsing of the gut may help keep brain activity organized. Indeed, it seems that how we think and see the world is affected by our heartbeat.
Med Page Today
FEBRUARY 9, 2024
(MedPage Today) -- Senators pummeled the CEOs of three of the largest pharmaceutical companies with demands that they explain why one in four Americans can't afford their prescription drugs, prices of which are higher in the U.S. compared with.
HCPLive
FEBRUARY 4, 2024
In this interview, Eichenfield discussed the recent pooled analysis from two phase 3 studies looking at once-daily, topical roflumilast for patients 6 and older with eczema.
Journal of Clinical Investigation - Cardiology
FEBRUARY 1, 2024
This study investigates a mechanistic link of bacterial biofilm–mediated host-pathogen interaction leading to immunological complications associated with breast implant illness (BII). Over 10 million women worldwide have breast implants. In recent years, women have described a constellation of immunological symptoms believed to be related to their breast implants.
American Heart News - Stroke News
FEBRUARY 9, 2024
Research Highlights: In the EMBOLISE clinical trial, obstructing (or blocking) an artery that supplies blood to the dura, the protective covering of the brain, along with surgery to remove pooled blood reduced the chances by nearly 3-fold that blood.
Dr. Smith's ECG Blog
FEBRUARY 16, 2024
Written by Pendell Meyers A teenager was playing basketball when he suddenly developed palpitations and lightheadedness. He presented soon afterward at the Emergency Department with ongoing symptoms. Mentation and blood pressure were normal. He had no chest pain or shortness of breath. Heart rates on the monitor fluctuated from 180-250 bpm. Here is his triage ECG: What do you think?
Medical Xpress - Cardiology
FEBRUARY 21, 2024
Using intravascular imaging to guide stent implantation during percutaneous coronary intervention (PCI) in heart disease patients significantly improves survival and reduces adverse cardiovascular events compared to angiography-guided PCI alone, the most commonly used method.
Med Page Today
FEBRUARY 16, 2024
(MedPage Today) -- NATIONAL HARBOR, Md. -- Moms who had hypertensive disorders of pregnancy (HDP) or gestational diabetes mellitus (GDM) were more likely to have kids with worse cardiovascular health (CVH) in adolescence, a secondary analysis.
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