July, 2024

article thumbnail

Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery

Cardiovascular Diabetology

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition that is characterized by unresolved fatigue, post-exertion symptom exacerbation (PESE), cognitive dysfunction, or.

Research 145
article thumbnail

COVID May Affect Type 1 Diabetes in Kids, and Not in a Good Way

Med Page Today

(MedPage Today) -- COVID-19 may accelerate progression of presymptomatic type 1 diabetes in youth, a German study suggested. Incidence of clinical type 1 diabetes nearly doubled after the pandemic started among 591 youth ages 1 to 16 known to.

COVID-19 144
article thumbnail

ECG Blog #437 — A 2-Part Answer.

Ken Grauer, MD

I was sent the ECG in Figure-1 — but without the benefit of any history. QUESTIONS: How would YOU interpret this tracing? WHY do I say there is, "A 2-Part Answer?" Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ). MY Thoughts on Today's CASE: As important as providing a brief, relevant history is for optimal clinical ECG interpretation — Cases like the one today often prove even more educational, because we are not given any

Blog 139
article thumbnail

White adipocytes in subcutaneous fat depots require KLF15 for maintenance in preclinical models

Journal of Clinical Investigation - Cardiology

Healthy adipose tissue is essential for normal physiology. There are 2 broad types of adipose tissue depots: brown adipose tissue (BAT), which contains adipocytes poised to burn energy through thermogenesis, and white adipose tissue (WAT), which contains adipocytes that store lipids. However, within those types of adipose, adipocytes possess depot and cell-specific properties that have important implications.

Obesity 139
article thumbnail

What are treatment options for this rhythm, when all else fails?

Dr. Smith's ECG Blog

Written By Magnus Nossen — with edits by Ken Grauer and Smith. The patient in today’s case is a previously healthy 40-something male who contacted EMS due to acute onset crushing chest pain. The pain was 10/10 in intensity radiating bilaterally to the shoulders and also to the left arm and neck. The below ECG was recorded. The ECG shows obvious STEMI(+) OMI due to probable proximal LAD occlusion.

article thumbnail

Study discovers connection between between heart and brain in KBG syndrome

Medical Xpress - Cardiology

A new study sheds light on a medical question scientists have long wondered: why do 40% of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain. The research is published in the journal Nature Communications.

Research 132
article thumbnail

30-year risk of cardiovascular disease may help inform blood pressure treatment decisions

Science Daily - Heart Disease

According to a new study, both 30-year risk for cardiovascular disease in addition to 10-year risk may be considered in making decisions about when to initiate high blood pressure medication.

More Trending

article thumbnail

Empowering Patients with Educational Resources for Kidney Disease, with Mike Spigler

HCPLive

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

article thumbnail

Texas Heart Institute implants artificial heart

Becker's Hospital Review - Cardiology

"Discover the groundbreaking success of the first-in-human implantation of the BiVACOR Total Artificial Heart by the Texas Heart Institute, offering hope for he

article thumbnail

A prehospital ECG in a patient with chest pain. The paramedics tell me it is normal.

Dr. Smith's ECG Blog

I was working at triage when the medics brought this patient who is 65 yo and has had chest pain for 12 hours. They recorded a prehospital ECG at 2112 and said that it was “normal”. It had already been crumpled up and put in the waste basket. So I uncrumpled it: What do you think? You need to click on it to enlarge it to view it well I was suspicious for inferior and posterior OMI (Large T-wave in aVF, slight STE in lead III with inverted T-wave in aVL, and a slightly downsloping ST with negativ

article thumbnail

AI speeds up heart scans, saves time, and could lead to better treatment for heart conditions

Medical Xpress - Cardiology

Researchers have developed a method for analyzing heart MRI scans with the help of artificial intelligence, which could save valuable NHS time and resources, as well as improve care for patients.

Research 115
article thumbnail

Artificial intelligence speeds up heart scans, saving doctors' time, and could lead to better treatment for heart conditions

Science Daily - Heart Disease

Researchers have developed a groundbreaking method for analysing heart MRI scans with the help of artificial intelligence, which could save valuable time and resources, as well as improve care for patients.

Research 115
article thumbnail

Semaglutide May Be Linked to Condition That Causes Blindness

Med Page Today

(MedPage Today) -- Use of the GLP-1 receptor agonist semaglutide (Ozempic, Wegovy) may be linked with an increased risk of the second most common form of optic neuropathy, a retrospective study suggested. Over a mean follow-up of nearly 3 years.

133
133
article thumbnail

Few Youth Receive Lipid Screening, Highlighting Missed Opportunity to Reduce CVD Risk

HCPLive

Despite recommendations, an analysis of more than 3.2 million youths suggests fewer than 15% of children/adolescents receive lipid screening.

114
114
article thumbnail

Baylor St. Luke’s Settles Concurrent Cardiac Surgery Case

CardiacWire

Cardiac surgeon compensation is generally a numbers game – the more procedures you do, the more you make. However, a Medicare fraud settlement featuring some of Houston’s most prominent institutions and cardiac surgeons reveals the pitfalls of this incentive structure. Allegations claim that between 2013 to 2020 three decorated Baylor St. Luke’s heart surgeons regularly operated in two to three rooms simultaneously, while “delegating key aspects of extremely complicated and risky heart sur

Medicare 109
article thumbnail

Two researchers to receive first-ever Ralph L. Sacco Scholarships for Brain Health

American Heart News - Stroke News

DALLAS and MINNEAPOLIS, July 2, 2024 — The American Academy of Neurology and the American Heart Association have awarded the first-ever Ralph L. Sacco Scholarships for Brain Health to two researchers, Patrick Devlin, Ph.D., of Houston, Texas, and Cyprien.

Research 114
article thumbnail

Mediterranean diet linked to lower risk of mortality, especially from cardiovascular disease, in cancer survivors

Medical Xpress - Cardiology

The Mediterranean diet is a powerful ally for health even after a cancer diagnosis. This is the key result of an Italian study carried out as part of the UMBERTO Project, conducted by the Joint Research Platform Umberto Veronesi Foundation—Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed of Pozzilli, in collaboration with the LUM "Giuseppe Degennaro" University of Casamassima (BA).

Diet 116
article thumbnail

Brain-heart axis: Strokes change epigenetics of immune system

Science Daily - Heart Disease

A stroke not only causes acute damage to the brain, but can also have long-term health implications for other organs -- such as the heart. Researchers have worked on the hypothesis that the high rate of comorbidities that develop after a stroke could have a common immunological cause. And they actually managed to find it: The origin of the dysfunctions in other parts of the body lies in the immunological memory of the blood-forming cells in bone marrow.

Stroke 103
article thumbnail

Mediterranean Diet Good for Kids, Teens Too

Med Page Today

(MedPage Today) -- The Mediterranean diet improved cardiometabolic health among kids and teens, a meta-analysis of randomized clinical trials affirmed. Interventions following the diet's characteristic emphasis on fruit, vegetables, olive oil.

Diet 127
article thumbnail

A man in his 50s with unwitnessed VF arrest, defibrillated to ROSC, and no STEMI criteria on post ROSC ECG. Should he get emergent angiogram?

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 50s was found by his family in cardiac arrest of unknown duration. His family started CPR and called EMS, who arrived to find him in ventricular fibrillation. 15 minutes after EMS arrival, after at least 6 defibrillations, the patient achieved sustained ROSC. He arrived to the ED with severe hypotension, heart rate in the 70s, unable to follow commands but moving all extremities requiring restraint and sedation, respiratory rate around 24/min being supporte

article thumbnail

Serum Complement Levels Demonstrate Prognostic Value in IgA Nephropathy

HCPLive

Integrating serum C3 and C4 levels into existing prognostic scores led to better prediction accuracy and may help optimize risk stratification in patients with IgAN.

102
102
article thumbnail

U.S. News Hospital Rankings Are One Piece of the CHD Care Puzzle

Conquering CHD

Where to receive care is one of the most important decisions a family can make. Conquering CHD has a strong commitment to transparency and ensuring patients and families have essential information at their fingertips when they need it to assist them in making the best choice for their family. With the publishing of this year’s U.S. News & World Hospital Report rankings , we remind you this is only one of many tools you can use to have a conversation with your care team and should not be used

Hospital 105
article thumbnail

Association of diabetes with cardiovascular calcification and all-cause mortality in end-stage renal disease in the early stages of hemodialysis: a retrospective cohort study

Cardiovascular Diabetology

The main goal of this study was to examine how diabetes, cardiovascular calcification characteristics and other risk factors affect mortality in end-stage renal disease (ESRD) patients in the early stages of h.

Diabetes 104
article thumbnail

Combining popular diabetes drugs offers complementary heart and kidney benefits

Science Daily - Heart Disease

New research shows combined use of sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP1-RAs) is likely to offer additional protection against heart and kidney disease in patients with diabetes.

Diabetes 111
article thumbnail

Nasal Sprays for Respiratory Infections; Paxlovid in COVID Prevention

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

115
115
article thumbnail

Stroke recovery: It's in the genes

Science Daily - Stroke

New research has found that specific genes may be related to the trajectory of recovery for stroke survivors, providing doctors insights useful for developing targeted therapies.

Stroke 95
article thumbnail

Circadian disruption, clock genes, and metabolic health

Journal of Clinical Investigation - Cardiology

A growing body of research has identified circadian-rhythm disruption as a risk factor for metabolic health. However, the underlying biological basis remains complex, and complete molecular mechanisms are unknown. There is emerging evidence from animal and human research to suggest that the expression of core circadian genes, such as circadian locomotor output cycles kaput gene (CLOCK), brain and muscle ARNT-Like 1 gene (BMAL1), period (PER), and cyptochrome (CRY), and the consequent expression

Obesity 145
article thumbnail

SGLT2 Inhibitor, GLP-1 RA Combination Improves Cardiovascular, Kidney Outcomes in Diabetes

HCPLive

Findings from a meta-analysis examining 12 trials including more than 70,000 patients with diabetes support combining SGLT2 inhibitors and GLP-1 RAs.

Diabetes 119
article thumbnail

Prevalence and incidence of heart failure in type 2 diabetes patients: results from a nationwide prospective cohort—the DIABET-IC study

Cardiovascular Diabetology

Type 2 diabetes (T2D) patients have an increased risk of heart failure (HF). There are limited data on the association between HF and T2D in specific healthcare settings. This study sought to analyse the preva.

article thumbnail

New study identifies two proteins that may contribute to stroke recurrence

Science Daily - Heart Disease

A new study has identified new genetic and molecular risk factors that may reveal new pathways for treating patients after they experience their first stroke. The study identified CCL27 and TNFRSF14, two proteins that are associated with subsequent MACE, but not initial strokes. These proteins are known to activate inflammation, which plays a key role in the development of strokes and many chronic conditions and diseases.

Stroke 95
article thumbnail

Persistent Anxiety Tied to Future Dementia

Med Page Today

(MedPage Today) -- Persistent anxiety raised the risk of all-cause dementia in older adults, a longitudinal study showed. Both chronic anxiety (HR 2.80, 95% CI 1.35-5.72, P=0.01) and new-onset anxiety (HR 3.20, 95% CI 1.40-7.45, P=0.01) were tied.

Dementia 108
article thumbnail

New study finds cardiovascular outcomes better for patients on home hemodialysis

Medical Xpress - Cardiology

Dialysis patients using a more traditional home hemodialysis procedure have lower incidence of cardiovascular disease than patients using a less invasive peritoneal catheter for dialysis at home, according to a study led by a University of Cincinnati College of Medicine researcher.

article thumbnail

Early surgery to prevent embolic events in patients with infective endocarditis: a comprehensive review

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a dangerous and lethal illness with high mortality rates. One of the main indications for surgery according to the guidelines is prevention of embolic events. However, uncertaint.

article thumbnail

HBV, HCV Screening Disparities Among Low-Income US Veterans

HCPLive

An analysis of data from the NV-HOPE study calls attention to lower rates of HBV and HCV screening among low-income US veterans versus the general US veteran population.

107
107
article thumbnail

Physiology Friday #226: Optimizing Post-exercise Recovery: Embrace Heat and Forget about Cold

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

Exercise 105
article thumbnail

HeartFlow Introduces Next Generation Interactive Plaque Analysis Platform to Assess Patient Risk in Suspected Coronary Artery Disease

DAIC

mtaschetta-millane Thu, 07/18/2024 - 10:00 July 18, 2024 — HeartFlow, Inc. , a leader in non-invasive artificial intelligence (AI) heart care solutions, introduced the next generation HeartFlow Plaque Analysis with an interactive experience. This upgraded platform is the only plaque analysis tool fully integrated with FFR CT (when FFR CT is performed), delivering impactful insights to enhance clinical decision-making and enabling personalized patient treatment plans.

article thumbnail

In Parkinson's Disease, Cognitive Symptoms Often Emerge Soon After Diagnosis

Med Page Today

(MedPage Today) -- About a third of people with Parkinson's disease reported cognitive symptoms early in the disease course, a large cross-sectional study showed. Of 25,000 Fox Insight study participants who had a Parkinson's diagnosis for a median.

116
116