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CVD Risk in Cancer Survivors Varies By Cancer Type and Treatment

American College of Cardiology

The long-term risk of cardiovascular disease (CVD) among cancer survivors can vary significantly based on cancer type and treatment, according to a nationwide cohort study published June 17 in JACC: CardioOncology.

Cancer 66
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Researchers Link Infant Heart Defects, Childhood Cancer

DAIC

tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. are forms of congenital heart defects (CHD). Lopez, M.D.,

Cancer 52
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Cardiovascular Toxicity in Patients Treated for Childhood Cancer: A Scientific Statement From the American Heart Association

Circulation

The field of cardio-oncology has expanded over the past 2 decades to address the ever-increasing issues related to cardiovascular disease in patients with cancer and survivors.

Cancer 55
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Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression

Journal of Clinical Investigation - Cardiology

These findings show that the GGT domain of LH2 is protumorigenic, identify Col6 as a candidate effector, and provide a rationale to develop pharmacological strategies that target LH2s GGT domain in cancer cells.

Cancer 59
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Lung cancer and risk of cardiovascular mortality

Frontiers in Cardiovascular Medicine

PurposeThe aim of the present study was to investigate the cardiovascular mortality risk among lung cancer patients compared to the general population.MethodsUsing data from the National Cancer Institute's Surveillance, Epidemiology, and End Results program, we conducted a population-based cohort study including 278,418 lung cancer patients aged over (..)

Cancer 52
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AMPK is necessary for Treg functional adaptation to microenvironmental stress during malignancy and viral pneumonia

Journal of Clinical Investigation - Cardiology

CD4+FOXP3+ Treg cells maintain self tolerance, suppress the immune response to cancer, and protect against tissue injury during acute inflammation. These results define AMPK as a determinant of Treg cell adaptation to metabolic stress and offer potential therapeutic targets in cancer and tissue injury.

Cancer 105
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ACAT1 regulates tertiary lymphoid structures: A target for enhancing immunotherapy in non–small cell lung cancer

Journal of Clinical Investigation - Cardiology

Nonsmall cell lung cancer (NSCLC), the most common type of lung cancer, remains a leading cause of cancer-related mortality worldwide. Immune checkpoint inhibitors (ICIs) have emerged as a promising therapy for NSCLC but only benefit a subset of patients. In this issue of the JCI, Jiao et al.

Cancer 50