Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression
JAMA Cardiology
JULY 16, 2024
This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.
Stenosis Related Topics 
Lp(a) and Calcific Aortic Valve Stenosis Progression
American College of Cardiology
JULY 23, 2024
What is the association between plasma lipoprotein(a) [Lp(a)] concentrations and hemodynamic progression in patients with aortic stenosis?
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Association between triglyceride-glucose index and intracranial/extracranial atherosclerotic stenosis: findings from a retrospective study
Cardiovascular Diabetology
MARCH 13, 2024
The association of the triglyceride-glucose (TyG) index with intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS) is unclear. This study aimed to investigate the relati.
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A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression
JAMA Cardiology
APRIL 5, 2024
This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.
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Heart-Valve-Surgery.Com and Medtronic Launch Novel "Aortic Stenosis Patient Activation Platform" to Empower Patients
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
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Aortic Valve Calcification in Low-Gradient Aortic Stenosis
American College of Cardiology
MAY 24, 2024
What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?
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Medtronic Announces FDA Approval of Newest-generation Evolut TAVR System for Treatment of Symptomatic Severe Aortic Stenosis
DAIC
MARCH 28, 2024
milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis. Aortic stenosis.
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Abbott Announces First Procedures in ENVISION Trial of Navitor TAVI System to Treat Patients With Severe Aortic Stenosis
DAIC
MARCH 25, 2024
The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve). fall into this category.
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Link Between Clonal Hematopoiesis and Stroke in Carotid Stenosis
All About Cardiovascular System and Disorders
MAY 22, 2024
About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol. doi: 10.1016/j.jacc.2024.03.389.
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Photon-Counting Detector CT Virtual Monoenergetic Images for Coronary Artery Stenosis Open configuration options
DAIC
JANUARY 11, 2024
82-year-old man with calcified stenosis in left main artery who underwent coronary CTA by PCD CT. Curved multiplanar reformatted images at varying virtual monoenergetic imaging (VMI) levels (40-140 keV) show stenosis at each level. Percent diameter stenosis (PDS) decreased from 92.5% at 40 keV to 53.1% at 140 keV. at 140 keV.
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Heart-Valve-Surgery.Com, Medtronic Launch Novel 'Aortic Stenosis Patient Activation Platform' to Empower Patients
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
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Severe Aortic Stenosis, Titration and Acute Heart Failure, Pacemakers After TAVR
American College of Cardiology
JUNE 18, 2024
In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.
ECG in LMCA Stenosis
All About Cardiovascular System and Disorders
APRIL 13, 2024
Such a pattern is consistent with significant left main coronary artery stenosis. Angiography done after initial stabilization showed severe stenosis of distal left main coronary artery. ST segment elevation is noted in aVR. Clinical evaluation and X-Ray chest showed features of pulmonary edema.
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A wolf in sheep's clothing—aortic stenosis and cardiac amyloidosis: “RAISE”ing awareness in clinical practice
Frontiers in Cardiovascular Medicine
FEBRUARY 23, 2024
This concept should be applied when managing older patients with severe aortic stenosis. Although left ventricular wall hypertrophy is expected in patients with aortic stenosis, it should not be assumed that this is caused only by aortic stenosis.
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Coronary-Artery Autoregulation with Increasing Stenosis
The New England Journal of Medicine
JUNE 5, 2024
In this experiment, investigators demonstrated autoregulation of coronary-artery blood flow in response to increasing stenosis using continuous thermodilution.
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William M. Feinberg Lecture: Asymptomatic Carotid Stenosis: Current and Future Considerations
Stroke Journal
JUNE 26, 2024
Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Features like intraplaque hemorrhage on MRI and echolucency on B-mode ultrasonography can identify patients at higher risk of stroke with asymptomatic stenosis.
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40 Computed Tomography Evaluation of Native Aortic Stenosis Beyond Calcification Score
American College of Cardiology
FEBRUARY 21, 2024
Echocardiography remains the principal imaging modality for detection and diagnosis of aortic stenosis (AS), as well as for grading of severity.
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Patient-specific 3D in vitro modeling and fluid dynamic analysis of primary pulmonary vein stenosis
Frontiers in Cardiovascular Medicine
JULY 5, 2024
IntroductionPrimary pulmonary vein stenosis (PVS) is a rare congenital heart disease that proves to be a clinical challenge due to the rapidly progressive disease course and high rates of treatment complications.
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52 Mitral Annulus Calcium Score in Patients With Calcific Mitral Stenosis Undergoing Invasive Hemodynamic Assessment
Journal of the American Heart Association
JANUARY 19, 2024
BackgroundAortic valve calcium score is associated with hemodynamic severity of aortic stenosis. There was no correlation between MAC calcium score and mitral valve area (r=0.07;P=0.6) or mitral valve gradient (r=−0.03;P=0.8).ConclusionsMAC
Severe Aortic Stenosis: Secular Trends of Incidence and Outcomes
American College of Cardiology
JUNE 11, 2024
What is the change in incidence, clinical presentation, treatment, and outcome for quantitatively defined severe aortic stenosis (AS) over the last 20 years in a population-based community?
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Common Carotid Artery Stenosis Degree as a Predictor of Cardiovascular Disease in a General Population: The Suita Study
Journal of the American Heart Association
DECEMBER 20, 2023
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovascular disease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
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Interactive Online Decision Aid Improves Shared Decision-Making For Patients With Severe Aortic Stenosis
American College of Cardiology
JUNE 7, 2024
A novel interactive, online decision aid used at the point of care among patients with severe aortic stenosis (AS) was strongly endorsed by patients and clinicians, easy to use and improved the quality of shared decision-making with a treatment decision that reflected patient values.
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Aortic Valve Calcification and Aortic Stenosis, Microvascular Resistance Reserve After PCI, Microvascular Injury Patterns
American College of Cardiology
MAY 29, 2024
In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis.
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Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome
Frontiers in Cardiovascular Medicine
APRIL 24, 2024
With this longer lifespan, calcific aortic stenosis (AS) was identified as an emerging critical risk factor for cardiac death in older patients. The only approved treatment is the farnesyltransferase inhibitor lonafarnib, which improves vascular structure and function, extending average untreated lifespan of 14.5 years by 4.3 years (30%).
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TAVR or SAVR in Severe Aortic Stenosis and Small Aortic Annulus
American College of Cardiology
MARCH 6, 2024
What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?
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Abstract TP299: The Relationship Between Intracranial Arterial Stenosis Rate and Cerebral Perfusion
Stroke Journal
FEBRUARY 1, 2024
PR was calculated as the ratio of proximal to distal pressure at the stenosis site, indicating post-stenosis blood flow. Arterial stenosis severity was categorized using the WASIDMethod:50%-69% for moderate and 70%-99% for severe. frequency was significantly higher in severe compared to moderate stenosis (P=0.01).
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40 ACCEL Lite: From JACC: Managing Patients with Moderate Aortic Stenosis
American College of Cardiology
JANUARY 16, 2024
In this review, authors discuss how multimodality imaging can help to evaluate the left ventricular remodeling response and improve risk stratification in patients with moderate aortic stenosis.
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Towards a gender-specific and morphology-specific assessment of aortic valve stenosis severity
Heart BMJ
MARCH 22, 2024
Over the last two decades, the differentiation of severe from non-severe aortic valve stenosis with echocardiography has become more complex. The consideration of flow is now frequently essential to evaluate haemodynamic stenosis severity. Low flow can result in low gradient and, thereby, mask severe aortic stenosis.
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Modified blade: an interventional option in rigid bronchoscopy for non-resectable benign tracheal stenosis
Journal of Cardiothoracic Surgery
FEBRUARY 7, 2024
Benign tracheobronchial stenosis is a abnormal tracheal lumen narrowing that may incur progressive dyspnea and life-threatening hypoxemia. There is no consensus on which patients should be treated with endosco.
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Randomized, Multicenter, Event-Driven Trial of TAVI Versus SAVR in Patients With Symptomatic Severe Aortic-Valve Stenosis
American College of Cardiology
APRIL 8, 2024
The goal of the DEDICATE-DZHK6 trial was to evaluate transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and low to intermediate surgical risk.
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MindMics Demonstrates Its In-ear Infrasonic Earbud Technology Shows Promise in Detection of Aortic Stenosis and Hearing Heart Murmurs
DAIC
DECEMBER 26, 2023
reported results from a clinical study of revolutionary earbuds that use a new technology - In-ear Infrasonic Hemodynography to Detects Aortic Stenosis Murmur Before and After Transcatheter Aortic Valve Replacement (TAVR). We propose a new method of assessing aortic stenosis through IH to detect its characteristic systolic ejection murmur."
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The Changing Landscape of Aortic-Valve Stenosis Management
The New England Journal of Medicine
NOVEMBER 22, 2023
Aortic-valve stenosis is an increasingly important cause of cardiovascular disease, particularly among older adults, with an overall prevalence of 2.8% 1 Aortic stenosis is a progressive disease in which the rate of change of the aortic-valve area is estimated to be. among adults older than 75 years of age.1
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Outcomes in patients with aortic stenosis and severely reduced ejection fraction following surgical aortic valve replacement and transcatheter aortic valve replacement
Journal of Cardiothoracic Surgery
APRIL 19, 2024
Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnit.
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Biomimetic transcatheter aortic heart valve offers new option for aortic stenosis patients
Medical Xpress - Cardiology
MAY 3, 2024
Recent findings from a study on a transcatheter heart valve (THV) system, which includes a new class of transcatheter aortic valve, showed positive results in the device's ability to function as a healthy and natural aortic valve in patients with aortic stenosis (AS).
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Aerodynamic evaluation of surgical design for the stenosis correction of airway
Frontiers in Cardiovascular Medicine
MARCH 27, 2024
Introduction Congenital tracheal stenosis (CTS) is a rare but life-threatening disease that can lead to respiratory dysfunction in children. The order of correction for CTS or OSAS greatly affected the aerodynamic parameters and turbulence flows downstream of tracheal stenosis and upstream of epiglottis.
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Abstract WMP116: A P2X4 Inhibitor Dramatically Suppresses the Progression of Cervical Internal Carotid Artery Stenosis - An Attempt to Develop a Therapeutic Agent for Carotid Artery Stenosis Focusing on the Role of Hemodynamic Factors-
Stroke Journal
FEBRUARY 1, 2024
Introduction:Medical treatment of internal carotid artery stenosis consists of treatment of underlying conditions such as hypertension, dyslipidemia, and diabetes mellitus, as well as antiplatelet therapy. This may lead the way to new drug therapies for carotid artery stenosis.
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40 PO-06-006 OUTCOMES OF PERCUTANEOUS BALLOON VENOPLASTY FOR SYMPTOMATIC LEAD-RELATED VENOUS STENOSIS
HeartRhythm
APRIL 30, 2024
Venous stenosis is a common complication of transvenous lead implantation, but optimal management for symptomatic patients has not been well defined.
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Future of Endovascular and Surgical Treatments of Atherosclerotic Intracranial Stenosis
Stroke Journal
JANUARY 21, 2024
Intracranial atherosclerotic disease and resultant intracranial stenosis is a global leading cause of stroke, and poses an ongoing treatment challenge. Among patients with intracranial stenosis, those with hemodynamic compromise are at high risk for recurrent stroke despite medical therapy and risk factor modification.
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40 Randomized Secondary Prevention Trials in Participants With Symptomatic Intracranial Atherosclerotic Stenosis
Stroke Journal
JANUARY 21, 2024
Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. Despite extensive research on secondary stroke prevention treatment over the past several decades, intracranial atherosclerotic stenosis continues to exhibit a notably higher recurrent stroke rate compared with other causes.
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40 Nonmalignant tracheal stenosis: presentation, management and outcome in limited resources setting
Journal of Cardiothoracic Surgery
JANUARY 22, 2024
Nonmalignant tracheal stenosis is a potentially life threatening conditions that develops as fibrotic healing from intubation, tracheostomy, caustic injury or chronic infection processes like tuberculosis.
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Abstract TP220: Intracranial Dotter Angioplasty Using Tenzing for Symptomatic Atherosclerotic Stenosis: Initial Experience
Stroke Journal
FEBRUARY 1, 2024
The Tenzing was slowly inserted across the ICAD stenosis in each case under roadmap fluoroscopic guidance. Stenosis location was: 1 ICA, 7 M1, 4 M2, 2 vertebral. The average pre-treatment ICAD stenosis was 95±7%, including 6 patients (43%) with complete occlusion. The median age was 62±11 years and 6 were female (43%).
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40 Eagle’s Eye View: Sacubitril/Valsartan in Decompensated Heart Failure; Discordant Aortic Stenosis and Transcatheter Treatment of Tricuspid Valve Regurgitation
American College of Cardiology
MARCH 27, 2024
Eagle looks at sacubitril/valsartan in patients hospitalized with decompensated heart failure, then examines the prevalence and outcomes of patients with discordant high gradient aortic stenosis.
Emergent Large Vessel Occlusion due to Intracranial Stenosis: Identification, Management, Challenges, and Future Directions
Stroke Journal
JANUARY 21, 2024
This comprehensive literature review focuses on acute stroke related to intracranial atherosclerotic stenosis (ICAS), with an emphasis on ICAS-large vessel occlusion. Stroke, Volume 55, Issue 2 , Page 355-365, February 1, 2024.
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Perceval sutureless bioprosthesis versus Perimount sutured bioprosthesis for aortic valve replacement in patients with aortic stenosis: a retrospective, propensity-matched study
Journal of Cardiothoracic Surgery
FEBRUARY 13, 2024
Rapid-deployment aortic valve replacement (RDAVR) is an alternative to conventional AVR (cAVR) for aortic stenosis. Benefits include a reduction in operative times, facilitation of minimal access surgery and s.
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