Aortic Stenosis, Heart Failure, and Aortic Valve Replacement
JAMA Cardiology
OCTOBER 15, 2024
This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.
Stenosis Related Topics 
Is Cardiology Overtreating Aortic Stenosis? with Linda Gillam, MD, MPH
HCPLive
OCTOBER 11, 2024
be overtreating aortic stenosis. Linda Gillam, MD, MPH, discusses the idea that the cardiology community may.
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Heart-Valve-Surgery.Com and Medtronic Launch Novel "Aortic Stenosis Patient Activation Platform" to Empower Patients
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
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Distinct Genetic Risk Profile Found in Aortic Stenosis
American College of Cardiology
NOVEMBER 20, 2024
Which genetic and cardiovascular risk factors are aortic stenosis (AS)-specific, and which could be shared between AS and with coronary artery disease (CAD)?
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Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
American College of Cardiology
OCTOBER 28, 2024
The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).
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Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression
JAMA Cardiology
JULY 16, 2024
This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.
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85 Myocardial Fibrosis and Outcomes in Aortic Stenosis
American College of Cardiology
SEPTEMBER 27, 2024
How does diffuse interstitial myocardial fibrosis, as observed on cardiac magnetic resonance (CMR), correlate with clinical outcomes in moderate and asymptomatic severe aortic stenosis (AS)?
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Association between triglyceride-glucose index and intracranial/extracranial atherosclerotic stenosis: findings from a retrospective study
Cardiovascular Diabetology
MARCH 13, 2024
The association of the triglyceride-glucose (TyG) index with intracranial atherosclerotic stenosis (ICAS) and extracranial atherosclerotic stenosis (ECAS) is unclear. This study aimed to investigate the relati.
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A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression
JAMA Cardiology
APRIL 5, 2024
This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.
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Photon-Counting Detector CT Virtual Monoenergetic Images for Coronary Artery Stenosis Open configuration options
DAIC
JANUARY 11, 2024
82-year-old man with calcified stenosis in left main artery who underwent coronary CTA by PCD CT. Curved multiplanar reformatted images at varying virtual monoenergetic imaging (VMI) levels (40-140 keV) show stenosis at each level. Percent diameter stenosis (PDS) decreased from 92.5% at 40 keV to 53.1% at 140 keV. at 140 keV.
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Genetic Risk Profile in Aortic Stenosis Compared With Coronary Artery Disease
JAMA Cardiology
NOVEMBER 5, 2024
This genomewide association study examined specific genetic variants, pathways, and tissues associated with aortic stenosis independent of coronary artery disease in a meta-analysis of participants from 3 European cohorts.
Swift intervention with early surgery aids elderly heart patients with aortic stenosis, finds study
Medical Xpress - Cardiology
OCTOBER 29, 2024
Until now, patients with aortic stenosis—a narrowing of one of the heart's main valves—have had to wait until symptoms become severe before undergoing valve replacement.
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Abbott Announces First Procedures in ENVISION Trial of Navitor TAVI System to Treat Patients With Severe Aortic Stenosis
DAIC
MARCH 25, 2024
The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve). fall into this category.
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Medtronic Announces FDA Approval of Newest-generation Evolut TAVR System for Treatment of Symptomatic Severe Aortic Stenosis
DAIC
MARCH 28, 2024
milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis. Aortic stenosis.
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Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis
American College of Cardiology
SEPTEMBER 18, 2024
The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.
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Balloon Angioplasty 'Lite' Improves Key Intracranial Stenosis Outcomes
Med Page Today
SEPTEMBER 5, 2024
(MedPage Today) -- Submaximal balloon angioplasty for symptomatic intracranial atherosclerotic stenosis (ICAS) improved outcomes over aggressive medical management alone, the BASIS trial from China showed. The incidence of the composite of any.
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A simple way to estimate Trans-Aortic gradient without doppler in Aortic stenosis
Dr. S. Venkatesan MD
DECEMBER 1, 2024
Here is a simple research paper on echocardiography , yet comprehensive, that assessed aortic leaflet separation distance with mean aortic gradient and valve area in patients with aortic stenosis. Kudos to the authors.
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Aortic Valve Calcification in Low-Gradient Aortic Stenosis
American College of Cardiology
MAY 24, 2024
What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?
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Primary transcatheter dilation of the pulmonary valve in cyanotic patients with tetralogy of Fallot and dominant pulmonary valve stenosis
Frontiers in Cardiovascular Medicine
NOVEMBER 14, 2024
ConclusionPalliative transcatheter dilation of predominantly pulmonary valve stenosis in patients with TOF and predominantly pulmonary valve stenosis is safe and effective in palliating cyanosis in most patients. Seven patients needed transannular patching, and in 11, the PV could be preserved (including 7 with BRCTs).ConclusionPalliative
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59 Features and Prognosis of High-Gradient Aortic Stenosis
American College of Cardiology
SEPTEMBER 24, 2024
What are the clinical features and prognosis of patients with high-gradient (HG) aortic stenosis (AS) with a calculated aortic valve area (AVA) of >1.0
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How do you manage “one & a half”cm² mitral stenosis ?
Dr. S. Venkatesan MD
NOVEMBER 26, 2024
Right from the days we entered medical schools, severe mitral stenosis was defined by less than 1 cm² MVO by echocardiography. The bottom line is, we should not miss a functionally significant mitral stenosis, strictly adhering to the anatomical 1 cm² cut-off. There is something called low gradient severe MS (as in aortic stenosis).
Link Between Clonal Hematopoiesis and Stroke in Carotid Stenosis
All About Cardiovascular System and Disorders
MAY 22, 2024
About a fifth of all ischemic strokes are attributed to embolization of ruptured atherosclerotic plaque from carotid arterial stenosis. But it has been difficult to predict which person with asymptomatic carotid artery stenosis is likely to progress to symptomatic carotid disease and stroke. J Am Coll Cardiol. doi: 10.1016/j.jacc.2024.03.389.
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Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis
American College of Cardiology
OCTOBER 9, 2024
Is balloon angioplasty plus medical management superior to medical management alone in patients with symptomatic intracranial atherosclerotic stenosis?
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Lp(a) and Calcific Aortic Valve Stenosis Progression
American College of Cardiology
JULY 23, 2024
What is the association between plasma lipoprotein(a) [Lp(a)] concentrations and hemodynamic progression in patients with aortic stenosis?
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Heart-Valve-Surgery.Com, Medtronic Launch Novel 'Aortic Stenosis Patient Activation Platform' to Empower Patients
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
Heart Valves 59
59 FAVOR III Europe: QFR-Guided Strategy vs. FFR-Guided Strategy in Patients With Intermediate Coronary Stenosis
American College of Cardiology
OCTOBER 30, 2024
A quantitative flow ratio (QFR)-guided strategy did not provide the same prognostic benefits as a fractional flow reserve (FFR)-guided strategy for patients with intermediate coronary stenosis, based on findings from the FAVOR III Europe trial presented at TCT 2024 and simultaneously published in The Lancet.
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Transcatheter mitral valve replacement to treat rheumatic mitral stenosis: a case series
Frontiers in Cardiovascular Medicine
DECEMBER 4, 2024
BackgroundRheumatic mitral stenosis (RMS) is a common valvular heart disease in developing countries. We sought to evaluate the early experience of patients with RMS undergoing transcatheter mitral valve replacement (TMVR).MethodsIn MethodsIn this retrospective study, a total of 5 RMS patients accepted TMVR.
Percutaneous Balloon Venoplasty for Symptomatic Lead Related Venous Stenosis
HeartRhythm
OCTOBER 8, 2024
Lead-related venous stenosis (LRVS) is common after transvenous lead implantation and generally diagnosed incidentally. Symptomatic LRVS, causing discomfort and swelling, is less common.
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A wolf in sheep's clothing—aortic stenosis and cardiac amyloidosis: “RAISE”ing awareness in clinical practice
Frontiers in Cardiovascular Medicine
FEBRUARY 23, 2024
This concept should be applied when managing older patients with severe aortic stenosis. Although left ventricular wall hypertrophy is expected in patients with aortic stenosis, it should not be assumed that this is caused only by aortic stenosis.
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Abstract 4120743: MEK inhibition for recurring pulmonary valve stenosis in RASopathy patients
Circulation
NOVEMBER 11, 2024
However, the most recurrent cardiac complication in RASopathies is pulmonary valve stenosis (PVS). This has motivated compassionate use of MEK inhibition (MEKi) for rare, but potentially lethal complications such as hypertrophic cardiomyopathy and lymphatic disease.
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Computed Tomography Evaluation of Native Aortic Stenosis Beyond Calcification Score
American College of Cardiology
FEBRUARY 21, 2024
Echocardiography remains the principal imaging modality for detection and diagnosis of aortic stenosis (AS), as well as for grading of severity.
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ECG in LMCA Stenosis
All About Cardiovascular System and Disorders
APRIL 13, 2024
Such a pattern is consistent with significant left main coronary artery stenosis. Angiography done after initial stabilization showed severe stenosis of distal left main coronary artery. ST segment elevation is noted in aVR. Clinical evaluation and X-Ray chest showed features of pulmonary edema.
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Updates in Using TAVR for Treating Aortic Stenosis, with Linda Gillam, MD, MPH
HCPLive
OCTOBER 13, 2024
Linda Gillam, MD, MPH, discusses updates in the management of aortic stenosis, with a focus on use of TAVR.
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52 Severe Aortic Stenosis, Titration and Acute Heart Failure, Pacemakers After TAVR
American College of Cardiology
JUNE 18, 2024
In this week's View, Dr. Eagle looks at secular trends of incidence and outcomes in severe aortic stenosis. He then examines titration of medications after acute heart failure.
Abstract 4145373: PREVALENCE OF NON-RHEUMATIC MITRAL STENOSIS IN CHRONIC KIDNEY DISEASE: NATIONAL IN-PATIENT SAMPLE ANALYSIS
Circulation
NOVEMBER 11, 2024
Background:There have been several studies postulating the association between Mitral valve stenosis (MS) and Chronic Kidney Disease (CKD). The prevalence of non rheumatic Mitral stenosis (MS) in the admission cohort was analyzed. The association between the conditions was statistically significant.
Transcatheter aortic valve replacement in patients with systolic heart failure, aortic stenosis shows limited benefits
Medical Xpress - Cardiology
OCTOBER 29, 2024
Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).
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Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients With Severe Aortic Stenosis
American College of Cardiology
OCTOBER 28, 2024
The goal of the EVOLVED trial was to assess the safety and efficacy of early aortic valve replacement compared with conservative management among patients with asymptomatic severe aortic stenosis, normal ejection fraction (EF), and presence of myocardial fibrosis on cardiac magnetic resonance imaging (CMR).
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46 Disease drivers in aortic stenosis vs atherosclerosis
JAMA Cardiology
NOVEMBER 5, 2024
Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.
Common Carotid Artery Stenosis Degree as a Predictor of Cardiovascular Disease in a General Population: The Suita Study
Journal of the American Heart Association
DECEMBER 20, 2023
BackgroundThe utility of screening for the degree of common carotid artery (CCA) stenosis as a predictor of cardiovascular disease (CVD) in a general population remains unclear.Methods and ResultsWe studied 4775 Japanese men and women whose CCA was measured using bilateral carotid ultrasonography at baseline (April 1994–August 2001).
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Mitral Annulus Calcium Score in Patients With Calcific Mitral Stenosis Undergoing Invasive Hemodynamic Assessment
Journal of the American Heart Association
JANUARY 19, 2024
BackgroundAortic valve calcium score is associated with hemodynamic severity of aortic stenosis. There was no correlation between MAC calcium score and mitral valve area (r=0.07;P=0.6) or mitral valve gradient (r=−0.03;P=0.8).ConclusionsMAC
Coronary-Artery Autoregulation with Increasing Stenosis
The New England Journal of Medicine
JUNE 5, 2024
In this experiment, investigators demonstrated autoregulation of coronary-artery blood flow in response to increasing stenosis using continuous thermodilution.
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Cardiopulmonary exercise testing in aortic stenosis patients before and after aortic valve replacement
Open Heart
NOVEMBER 9, 2024
Background Knowledge about how patients with symptomatic aortic stenosis (AS) perform on cardiopulmonary exercise testing (CPET) is sparse. Since exercise testing in patients with symptomatic AS is not advised, submaximal parameters could be of special interest.
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Early transcatheter aortic valve replacement can be beneficial for asymptomatic severe aortic stenosis patients: Study
Medical Xpress - Cardiology
OCTOBER 29, 2024
The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).
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TAVR or SAVR in Severe Aortic Stenosis and Small Aortic Annulus
American College of Cardiology
MARCH 6, 2024
What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?
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