DAIC

JULY 15, 2025

Cleerly will be sharing findings on three scientific abstracts: an investigation into how AI-QCT influences physician prescribing practices, a pooled analysis comparing AI-QCT ISCHEMIA accuracy to alternative measurements, and a pooled analysis, per-vessel comparison of AI-QCT ISCHEMIA to alternative measurements.

Research 52

Research Ischemia Cardiovascular Imaging Technology 52

Frontiers in Cardiovascular Medicine

JUNE 12, 2025

IntroductionShexiang Tongxin Dropping Pills (STDP), a traditional Chinese medicine (TCM), is clinically used for cardiovascular diseases like myocardial ischemia.

Ischemia 40

Ischemia Myocardial Infarction Cardiac Function Arrhythmia 40

Cardiovascular Diabetology

JUNE 6, 2025

Heart failure with preserved ejection fraction (HFpEF) poses a significant global health challenge, disproportionately affecting women. Diabetic women with HFpEF represent a high-risk subgroup, particularly af.

Preserved Ejection Fraction 121

Preserved Ejection Fraction Diabetes Ischemia STEMI 121

ECG Guru

JULY 5, 2025

This shape represents ischemia in a patient with these symptoms and ECG findings. LAFB can be explained by this patient's history of prior CAD and valve replacement. There is ST elevation in Lead I and also in V1-V6. The ST segments have a straight shape in Leads I and aVL and in V1-V6. This is an ANTERIOR-LATERAL OCCLUSIVE M.I.

Aortic valve 94

Aortic valve Chest Pain Coronary Artery Disease Angioplasty 94

Cardiovascular Diabetology

JULY 9, 2025

Chronic limb-threatening ischemia (CLTI) presents a major clinical challenge in patients with Type 2 Diabetes Mellitus (T2DM), requiring lower extremity revascularization (LER) to mitigate adverse cardiovascul.

Ischemia 52

Ischemia Diabetes Research 52

All About Cardiovascular System and Disorders

JUNE 29, 2025

Dobutamine stress CMR is a sensitive and accurate method for detection and quantification of myocardial ischemia. CMR is also useful in the assessment of myocardial masses and fibrosis. Repeated CMR evaluations can be done to track progression of disease processes and results of therapeutic interventions, without fear of radiation hazards.

Congenital Heart Disease 52

Congenital Heart Disease Congenital Heart Disease Ischemia 52

Frontiers in Cardiovascular Medicine

MAY 15, 2025

ObjectiveTo compare the efficacy and safety outcomes between percutaneous mechanical thrombectomy (PMT) and catheter-directed thrombolysis (CDT) as the first endovascular revascularization (EVR) strategy for arterial acute mesenteric ischemia (AMI) and identify risk factors for 30-day mortality.MethodsThis was a single-center retrospective study.

Risk Factors 52

Risk Factors Thrombolysis Ischemia Outcomes 52

Medical Xpress - Cardiology

JUNE 19, 2025

A new statement from leading heart and blood vessel experts in Europe is providing clinical guidance for treatments to prevent blood clots in patients with a serious condition called chronic limb-threatening ischemia (CLTI), after they have had procedures to restore blood flow in their lower limbs.

Blood Clot 40

Blood Clot Research Ischemia 40

DAIC

JANUARY 13, 2025

tim.hodson Mon, 01/13/2025 - 16:24 A new studyreports persistent disparities in outcomes for people with peripheral artery disease (PAD) and its more severe form, chronic limb-threatening ischemia (CLTI) in the United States. Among 73,237 patients who underwent major lower extremity amputation, 55.1%

Peripheral Arterial Disease 52

Peripheral Arterial Disease Outpatient Ischemia Vascular Care 52

Dr. Smith's ECG Blog

SEPTEMBER 6, 2013

In the 1980's, it was believed that the right precordial ST depression that frequently accompanies inferior STEMI was due to "anterior subendocardial ischemia." Heart block in inferior STEMI is due to ischemia of the AV node. Then numerous angiographic studies refuted this and showed that it is almost always due to posterior STEMI.

Chest Pain 52

Chest Pain Bradycardia STEMI Atrial Fibrillation 52

Frontiers in Cardiovascular Medicine

APRIL 28, 2025

BackgroundTotal aortic arch replacement surgery (TARS) for Acute type A aortic dissection is associated with high incidence of postoperative acute kidney injury (AKI), at least partly due to the lower body ischemia during circulatory arrest.

Aortic 52

Aortic Ischemia Outcomes Research 52

Dr. Smith's ECG Blog

JANUARY 30, 2016

An ECG was recorded: There is ST depression in V3-V6 consistent with ischemia. Is it ischemia? is very short, and includes ischemia, hypokalemia, and digoxin effect. This patient had a subdural hematoma. When I saw this ECG, I thought: "That looks like hypokalemia." If it is QT, then the QT is impossibly long.

Ischemia 52

Ischemia 52

Dr. Smith's ECG Blog

OCTOBER 7, 2022

I thought that IF the ST depression seen in this ECG was the result of diffuse subendocardial ischemia — then instead of isoelectric ST segments in the lateral leads, there should be ST depression there as well. I therefore viewed the ST segments in the lateral leads as probably being inappropriately isoelectric.

Chest Pain 52

Chest Pain Cardiomyopathy Ischemia Myocardial Infarction 52

Ken Grauer, MD

DECEMBER 28, 2024

Unless a potentially fixable cause of this rhythm can be found ( ie, acute ischemia from recent infarction; electrolyte disturbance, use of rate-slowing medication ) the patient will need a pacemaker. This strongly suggests ischemia which could be recent and a contributing ( or precipitating) cause of todays abnormal rhythm.

Blog 171

Blog Ischemia Pacemaker 171

Dr. Smith's ECG Blog

NOVEMBER 15, 2021

STD Max V1-V4 can be due to subendocardial ischemia (not OMI) when there is tachycardia, especially if due to atrial fibrillation with RVR. He converted to sinus rhythm and we recorded this 12-lead ECG immediately after: Sinus rhythm with no evidence of OMI and some residual ischemia (ST depression), which eventually resolved.

Ischemia 52

Ischemia Atrial Fibrillation Chest Pain Tachycardia 52

Frontiers in Cardiovascular Medicine

MARCH 18, 2025

Finally, we also emphasize the preclinical/clinical translational significance of neutrophil-targeted strategies.

Cardiovascular Disease 52

Cardiovascular Disease Atrial Fibrillation Atherosclerosis Ischemia 52

Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

CTFFR can identify impaired myocardial strain and can be used as an indirect indicator of myocardial ischemia.

Stenosis 52

Stenosis Heart Disease Ischemia Research 52

Dr. Smith's ECG Blog

JANUARY 2, 2025

It should be kept in mind that on occasions, beta-one agonist can result in increased ventricular ectopy e.g., in severe myocardial ischemia (by increasing myocardial demand), or sometimes with congenital long-QT syndrome. Smith, this can be accomplished by either using beta-one agonists or temporary transvenous pacing.

Tachycardia 122

Tachycardia Cardiomyopathy Blog Bradycardia 122

Dr. Smith's ECG Blog

APRIL 14, 2017

There is STE in aVR (reciprocal ST elevation, reciprocal to the ST depression) This is classic diffuse subendocardial ischemia. ng/mL (expected with complete resolution of ischemia -- this rise is due to ischemia that occurred before the rate control). She was given a sublingual nitroglycerin and her BP dropped to 80 systolic.

Ischemia 52

Ischemia Atrial Fibrillation STEMI Chest Pain 52

DAIC

JUNE 6, 2025

For this study, MALE were defined as acute limb ischemia requiring thrombectomy or major amputation, and MACE were defined as myocardial infarction, stroke, acute ischemic heart disease, and heart failure. At one year, patients with moderate PAD who were started on GLP-1 RAs had fewer major adverse limb events (MALE) (0.8%

Peripheral Arterial Disease 52

Peripheral Arterial Disease Myocardial Infarction Blood Pressure Heart attacks 52

Dr. Smith's ECG Blog

JUNE 17, 2020

ST Depression in V2, V3 is most often due to "posterior" transmural ischemia (now called "lateral" by a convention that I disagree with because posterior and lateral MI are different on the ECG). However, sometimes it is due to subendocardial ischemia. What do you want to do? How do we make the distinction?

AFIB 52

AFIB Ischemia Atrial Fibrillation Bicuspid/Mitral 52

Journal of the American Heart Association

FEBRUARY 8, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundIschemic stroke is among the most prevalent diseases, with high death and morbidity. Numerous preclinical studies have reported efficacious interventions in rodent stroke models. However, reperfusion therapies remain the only clinically efficacious intervention to date.

Ischemia 45

Ischemia Strokes Stroke Outcomes 45

Frontiers in Cardiovascular Medicine

JUNE 16, 2025

Kounis syndrome is an allergic myocardial ischemia syndrome triggered by various factors. Herein, we presented a case of a patient with Multiple Myeloma who developed chest pain as a result of lenalidomide use. The patient’s electrocardiogram (ECG) revealed ST-segment depression, along with elevated troponin I and eosinophils levels.

Chest Pain 52

Chest Pain Myocardial Infarction Electrocardiogram Thrombosis 52

All About Cardiovascular System and Disorders

JULY 4, 2025

Primary endpoint was a composite of cardiovascular death, spontaneous myocardial infarction, ischemic stroke, or ischemia-driven coronary revascularization. LoDoCo2 from Australia, was a randomized controlled, double-blind trial in patients with chronic coronary artery disease. 5522 patients were randomized to either colchicine 0.5

Coronary Artery Disease 52

Coronary Artery Disease Myocardial Infarction Cardiac Arrest Pericarditis 52

Frontiers in Cardiovascular Medicine

JULY 15, 2025

Increasing evidence has revealed that dysregulation of mTOR activity, often triggered or exacerbated by aberrant post-translational modifications (PTMs), contributes to the onset and progression of cardiovascular diseases (CVDs), including atherosclerosis, myocardial infarction, heart failure, and ischemia-reperfusion injury.

Cardiovascular Disease 52

Cardiovascular Disease Myocardial Infarction Atherosclerosis Physiology 52

Dr. Smith's ECG Blog

JUNE 19, 2015

A patient with history of severe CAD, CABG, with all native vessels occluded, on maximal medical therapy presented with his typical angina. He had had several recent small NonSTEMIs that were treated medically. Here is his initial ECG: There is an LBBB-like QRS.

Ischemia 52

Ischemia Chest Pain Myocardial Infarction Anatomy 52

Ken Grauer, MD

JUNE 21, 2025

Although nonspecific — these abnormal ST-T wave changes could reflect recent ischemia and/or infarction as the potential cause of this patient's conduction defects! In the chest leads — odd-numbered beats #5 and 7 show persistent ST-T wave depression as far laterally as lead V5 ( which should not be seen with simple RBBB conduction ).

Blog 99

Blog Bradycardia Arrhythmia Pacemaker 99

Dr. Smith's ECG Blog

APRIL 3, 2019

So this shows ischemia. It may be Brugada + ischemia. Comment: This could still be Brugada phenotype with superimposed ischemia, as Brugada morphology can be intermittent. But more like the LAD ischemia manifested similarly to Brugada. This ECG has diffuse ST depression in II, III, aVF and V4-V6. Learning Point: 1.

Chest Pain 52

Chest Pain Ischemia STEMI Stents 52

Dr. Smith's ECG Blog

DECEMBER 3, 2024

A good size infarct that no longer has active ischemia will have continually rising troponins due to the damage that was done hours ago. The only way to know if this patient whom you know has Acute MI needs the cath lab is if 1) symptoms are present and can't be controlled or 2) the ECG shows active ischemia.

Catheterization Laboratory 116

Catheterization Laboratory Blog STEMI Ischemia 116

American College of Cardiology

MAY 6, 2025

Funded by the Congressionally Directed Medical Research Programs (CDMRP) of the Department of Defense, the WARRIOR (Women's IschemiA TRial to Reduce events In non-ObstRuctive CAD) Trial addresses the urgent need for evidence-based care in a growing population of patientsparticularly womenexperiencing ischemia without obstructive coronary artery disease (..)

Coronary Artery Disease 58

Coronary Artery Disease Ischemia Outcomes Research 58

Open Heart

JANUARY 20, 2025

Specifically, the study aimed to assess the target vessel's failure (TVF) at one year, which includes acute coronary syndrome (ACS), cardiac death, and ischemia-driven target vessel revascularization (TVR). The secondary objectives were total mortality, including cardiac death and non-cardiac death.

Outcomes 52

Outcomes Angioplasty Ischemia Risk Factors 52

Dr. Smith's ECG Blog

JANUARY 6, 2016

Pacemaker syndrome Is this Acute Ischemia? The Electrocardiographically Silent Circumflex Artery ST Segment Depression. Looking for a wall motion abnormality can lead you. Atrial Fib with RVR. What treatment? Inferior STEMI with AV Block, Cardiogenic Shock an. Shouldn't need Modified Sgarbossa rule for cath la. More on LVH.

STEMI 52

STEMI Tachycardia Pericarditis Atrial Fibrillation 52

Dr. Smith's ECG Blog

JANUARY 20, 2022

Wellens (1) PEA - Pulseless Electrical Activity (1) PERFECT study (3) PM Cardio Queen of Hearts (59) PR depression (1) PR interval (2) PVC (16) Pancreatitis (1) Panic attack (1) Papillary muscle (mitral valve) rupture (2) Paradox: No False Negative (1) Patent Foramen Ovale (1) Peaked T waves (6) Pediatric (15) Persistent Juvenile T-waves (3) Pleomorphic (..)

STEMI 52

STEMI Tachycardia Atrial Fibrillation Atrial Flutter 52

Dr. Smith's ECG Blog

APRIL 13, 2019

Wellens (1) PEA - Pulseless Electrical Activity (1) PERFECT study (3) PM Cardio Queen of Hearts (59) PR depression (1) PR interval (2) PVC (16) Pancreatitis (1) Panic attack (1) Papillary muscle (mitral valve) rupture (2) Paradox: No False Negative (1) Patent Foramen Ovale (1) Peaked T waves (6) Pediatric (15) Persistent Juvenile T-waves (3) Pleomorphic (..)

STEMI 52

STEMI Tachycardia Atrial Fibrillation Chest Pain 52

MIBHS

OCTOBER 31, 2024

This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge. Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart.

Blood Pressure 52

Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

Dr. Smith's ECG Blog

JANUARY 25, 2016

The ischemia on the ECG could be of several possible etiologies: 1) New atrial fib with RVR causing demand ischemia (but the rate is not terribly fast). 2) Old atrial fib with poor rate control causing demand ischemia. 3) ACS with possible additional ischemia from atrial fib with RVR 4) Hemorrhage/dehydration/sepsis/etc.,

Ultrasound 40

Ultrasound Ischemia Atrial Fibrillation Tachycardia 40

DAIC

APRIL 2, 2025

The primary endpoint was the one-year rate of target vessel failure, the composite occurrence of either cardiac death, target-vessel myocardial infarction, or ischemia-driven target-vessel revascularization.

Stents 40

Stents Stent Outcomes Coronary Angiogram 40