Medical Xpress - Cardiology

JANUARY 9, 2024

However, reperfusion itself could induce more severe injury, called myocardial ischemia/reperfusion injury (MI/RI). The most effective treatment for MI in clinic is reperfusion, e.g., interventional or thrombolytic therapy.

Ischemia 75

Ischemia Myocardial Infarction Research 75

Frontiers in Cardiovascular Medicine

FEBRUARY 1, 2024

In addition, with the prevalence of COVID-19 infection, more and more studies report that COVID-19 infection may lead to arteriovenous thrombosis, which could cause lower limb ischemia. This case reported that a 31-year-old male amateur football player who developed intermittent claudication after recovering from COVID-19.

COVID-19 64

COVID-19 Ischemia Thrombosis 64

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

Introduction Accurate identification of the myocardial texture features of fat around the coronary artery on coronary computed tomography angiography (CCTA) images are crucial to improve clinical diagnostic efficiency of myocardial ischemia (MI).

Ischemia 59

Ischemia 59

Medical Xpress - Cardiology

APRIL 10, 2024

A new study reveals diminished quality of life among patients with chronic limb-threatening ischemia, a severe form of peripheral artery disease, and emphasizes the benefits of revascularization on well-being.

Quality of Life 40

Quality of Life Ischemia Peripheral Arterial Disease 40

NEJM Journal Watch - Cardiology

APRIL 10, 2024

In a randomized, controlled trial, the device reduced daily angina but not myocardial ischemia in patients with refractory angina.

Angina 45

Angina Ischemia 45

Circulation: Cardiovascular Interventions

DECEMBER 28, 2023

BACKGROUND:Lower-limb amputation rates in patients with chronic limb-threatening ischemia vary across the United States, with marked disparities in amputation rates by gender, race, and income status. Circulation: Cardiovascular Interventions, Ahead of Print. Mean age, 76.6

Vascular Care 61

Vascular Care Ischemia Medicare Cardiovascular Interventions 61

American College of Cardiology

JANUARY 2, 2024

The goal of the MINT trial was to compare the effect of a liberal vs. restrictive blood transfusion strategy on acute myocardial infarction (MI) in patients with concomitant anemia.

Ischemia 75

Ischemia Myocardial Infarction Article 75

All About Cardiovascular System and Disorders

FEBRUARY 9, 2024

Why is left ventricle more prone for ischemia than right ventricle or atria?

Ischemia 52

Ischemia General Cardiology 52

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. Journal of the American Heart Association, Ahead of Print. Our analysis included 102 eligible studies.

Ischemia 40

Ischemia Hemorrhage Blood Pressure Aneurysm 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionAcute spinal cord ischemia syndrome (ASCIS) is a rare disease that is thought to comprise roughly only 1.2% Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. of all strokes [1, 2]. Due to the scarcity of these events, the patient outcomes are unclear.

Ischemia 40

Ischemia Myocardial Infarction Thrombosis Document 40

Frontiers in Cardiovascular Medicine

JANUARY 28, 2024

Background Impaired energy balance caused by lipid metabolism dysregulation is an essential mechanism of myocardial ischemia-reperfusion injury (MI/RI). This study aims to explore the lipid metabolism-related gene (LMRG) expression patterns in MI/RI and to find potential therapeutic agents.

Ischemia 59

Ischemia 59

Journal of Cardiovascular Pharmacology

APRIL 1, 2024

Abstract: N-n-butyl haloperidol iodide (F2), a derivative of haloperidol developed by our group, exhibits potent antioxidative properties and confers protection against cardiac ischemia/reperfusion (I/R) injury. The protective mechanisms by which F2 ameliorates I/R injury remain obscure.

Ischemia 40

Ischemia Pharmacology Heart Disease Article 40

Stroke Journal

FEBRUARY 1, 2024

To confirm the time-kinetics of cGK1/2 changes, brain samples were divided ischemia-reperfusion period in SMLC and SMKO mice with and without dipyridamole (60 mg/kg, p.o.).Results:Infarction During the ischemia and reperfusion period, neuronal cGK1 was sustained without protein degradation. Not only SMLC but also SMKO were the same.

Ischemia 40

Ischemia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

miR-155-5p ASO-treated PBMC administration increased VEGF expression 21 d after administration in ischemic rats (28 d after cerebral ischemia). Moreover, VEGF expression levels in the microglia cocultured with OGD-PBMCs were higher with miR-155-5p ASO than without it (P = 0.049).

Ischemia 40

Ischemia Stroke Strokes 40

Circulation: Cardiovascular Interventions

NOVEMBER 6, 2023

We sought to determine the substrates for ischemia in patients with angina, nonobstructive coronary arteries (ANOCA) and a MB in the left anterior descending artery.Methods:Patients with ANOCA underwent acquisition of intracoronary pressure and flow during rest, supine bicycle exercise and adenosine infusion.

Ischemia 40

Ischemia Exercise Angina Cardiovascular Interventions 40

Stroke Journal

FEBRUARY 1, 2024

This study aims to understand the role of SIRT3 on ischemia and reperfusion-induced neuronal apoptosis. One potential therapeutic target for reperfusion injury is Sirtuin 3 (SIRT3), which mediates the deacetylation of enzymes that are responsible for the reduction of ROS, leading to protection against oxidative stress.

Ischemia 40

Ischemia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Malonate, a competitive inhibitor of succinate dehydrogenase, has shown much promise in ameliorating ischemia/reperfusion injury (IRI) in various diseases, including ischemic stroke. Stroke, Volume 55, Issue Suppl_1 , Page AWMP12-AWMP12, February 1, 2024.

Ischemia 40

Ischemia Stroke Strokes Physiology 40

Journal of the American Heart Association

DECEMBER 29, 2023

BackgroundFerroptosis, an iron‐dependent form of regulated cell death, is a major cell death mode in myocardial ischemia reperfusion (I/R) injury, along with mitochondrial permeability transition‐driven necrosis, which is inhibited by cyclosporine A (CsA). Journal of the American Heart Association, Ahead of Print.

Ischemia 40

Ischemia Myocardial Infarction 40

ECG Cases

SEPTEMBER 23, 2019

And guess what.they all show acute ischemia! The post ECG Cases 1: Missed Ischemia – Never Trust the ECG Computer Interpretation appeared first on Emergency Medicine Cases.

Ischemia 52

Ischemia Chest Pain Blog STEMI 52

Stroke Journal

FEBRUARY 1, 2024

In this study, our hypothesis was that NETs cause vascular occlusion leading to delayed cerebral ischemia (DCI) and worse outcome after SAH. Following ischemic stroke, neutrophils cause vascular occlusion via neutrophil extracellular traps (NETs).

Ischemia 40

Ischemia Hemorrhage Aneurysm Outcomes 40

American College of Cardiology

APRIL 8, 2024

The goal of the ORBITA-COSMIC trial was to determine the effects of a coronary sinus reducer (CSR) device versus sham control on both myocardial blood flow (MBF) assessed by stress perfusion cardiac magnetic resonance imaging (CMR) and daily angina burden in patients with refractory angina.

Ischemia 53

Ischemia Angina Article 53

Stroke Journal

FEBRUARY 1, 2024

Background and Purpose:Neutrophils are the first recruited leukocytes following ischemia/reperfusion injury in the brain; however, when and where neutrophils enter the brain parenchyma to exert their effects is controversial. Stroke, Volume 55, Issue Suppl_1 , Page ATP309-ATP309, February 1, 2024.

Ischemia 40

Ischemia Stroke Strokes 40

Dr. Smith's ECG Blog

JULY 30, 2023

The STD maximal in V1-V4 is diagnostic of acute transmural posterior wall ischemia, most likely due to posterior OMI. Subendocardial ischemia does not localize, and subendocardial ischemia presents with STD maximal in V5-6, II, and STE in aVR. Subendocardial ischemia does not localize. AI can do it too.

Chest Pain 52

Chest Pain Ischemia STEMI Arrhythmia 52

Journal of the American Heart Association

JANUARY 19, 2024

BackgroundLittle is known about treatment variability across US hospitals for patients with chronic limb‐threatening ischemia (CLTI).Methods Journal of the American Heart Association, Ahead of Print. Methods and ResultsData were collected from the 2016 to 2018 National Inpatient Sample.

Inpatient 40

Inpatient Ischemia Hospital Outcomes 40

Journal of Cardiothoracic Surgery

MAY 3, 2024

Intravascular lithotripsy (IVL) represents a novel approach in the management of coronary calcification. This technique employs acoustic pressure waves, generated by a shockwave balloon, to effectively fractur.

Ischemia 52

Ischemia 52

Journal of Cardiothoracic Surgery

APRIL 11, 2024

Background The clinical presentation of left ventricular free wall rupture (LVFWR) varies ranging from uneventful condition to congestive heart failure. Case summary Here we report two cases of LVFWR with different clinical presentation and notable outcome.

Ischemia 52

Ischemia ICU Myocardial Infarction Aortic 52

Med Page Today

APRIL 29, 2024

(MedPage Today) -- The FDA approved the Esprit BTK everolimus-eluting scaffold system for chronic limb-threatening ischemia (CLTI) below the knee, Abbott announced on Monday. This system represents the first drug-eluting resorbable scaffold with.

Peripheral Arterial Disease 111

Peripheral Arterial Disease Stents Stent Ischemia 111

EMS 12-Lead

APRIL 9, 2024

Many of the changes seen are reminiscent of LVH with “strain,” and downstream Echo may very well corroborate such a suspicion, but since the ECG isn’t the best tool for definitively establishing the presence of LVH, we must favor a subendocardial ischemia pattern, instead. Type I ischemia. Type II ischemia.

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Ischemia Stenosis Coronary Artery Disease Chest Pain 116

CardiacWire

MAY 10, 2024

FFRCT analysis revealed high rates of asymptomatic lesion-specific coronary ischemia (65%), severe ischemia (52%), multivessel ischemia (36%), and left main ischemia (8%). Meanwhile, the usual care group’s coronary ischemia statuses remained unknown (because they didn’t test for it).

Coronary Artery Disease 59

Coronary Artery Disease Peripheral Arterial Disease Ischemia Myocardial Infarction 59

Dr. Smith's ECG Blog

APRIL 14, 2024

No ischemia. This is a conundrum, because it is clear that the patient is having an acute MI, the ECG is dynamic, but the pain is very mild and there is no ECG evidence of active transmural ischemia. We already know that the ischemia is ongoing, though mild (because of the persistent pain). Q-waves are even more pronounced.

Chest Pain 96

Chest Pain Ischemia Myocardial Infarction Ultrasound 96

Dr. Smith's ECG Blog

JANUARY 4, 2021

This suggests diffuse subendocardial ischemia. However, along with that subendocardial ischemia, there is also STE in lead III with reciprocal ST depression in aVL, and some STE in V1. If there is also subendocardial ischemia, the ST depression vector remains leftward, with a reciprocal ST Elevation vector also to the right.

Ischemia 52

Ischemia Pulmonary STEMI Chest Pain 52

Journal of the American Heart Association

FEBRUARY 14, 2024

Maternal blood and tissues were collected.

Ischemia 40

Ischemia Blood Pressure Circulation Hypertension 40

Dr. Smith's ECG Blog

NOVEMBER 26, 2018

In some cases the ischemia can be seen "through" the flutter waves, whereas in other cases the arrhythmia must be terminated before the ischemia can be clearly distinguished. First , there can simply be diffuse ST depressions (which obligates reciprocal STE in aVR) associated with tachycardia which are not indicative of ischemia.

Ischemia 52

Ischemia Atrial Flutter Arrhythmia Tachycardia 52

Circulation: Cardiovascular Interventions

DECEMBER 28, 2023

Circulation: Cardiovascular Interventions, Ahead of Print.

Ischemia 40

Ischemia Cardiovascular Interventions Circulation 40

DAIC

MARCH 27, 2024

Food and Drug Administration (FDA) for its DynamX BTK System, a novel, adaptive implant for use in the treatment of narrowed or blocked vessels below-the-knee (BTK) in patients with chronic limb-threatening ischemia (CLTI). The natural history of untreated severe or critical limb ischemia. 2013;382(9901):1329-1340. J Vasc Surg.

Peripheral Arterial Disease 95

Peripheral Arterial Disease Ischemia Technology Coronary Artery Disease 95

Dr. Smith's ECG Blog

JANUARY 2, 2016

There may be ischemia present, but it is not evident on the ECG. In this paper, Dr. Birnbaum writes: "In patients with ACS without LVH, ST depression with negative T waves in the lateral leads is a sign of sub-endocardial ischemia and is an independent predictor of adverse outcome [11 – 13].

Ischemia 52

Ischemia Chest Pain STEMI Myocardial Infarction 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A108-A108, February 1, 2024. Neonatal hypoxic ischemic encephalopathy (HIE) increases the risk for attention deficit disorder and autism spectrum disorders in children. Perturbations in the gut microbiome are associated with behavioral changes in pre-clinical models of neurological injury and development.

Ischemia 40

Ischemia Stroke Strokes 40