Medical Xpress - Cardiology

JANUARY 25, 2024

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes.

Cardiovascular Disease 133

Cardiovascular Disease Biomarkers Diabetes Academic 133

Science Daily - Heart Disease

MARCH 18, 2024

Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes. Coronary heart disease is a major global health problem, especially among people with type 2 diabetes.

Biomarkers 66

Biomarkers Heart Disease Diabetes Research 66

Medical Xpress - Cardiology

MARCH 18, 2024

The research team investigated the predictive performance of protein biomarkers on incident CHD in individuals with and without T2D. Among middle-aged adults, individuals with type 2 diabetes (T2D) have a two to four times higher risk of developing CHD than people without T2D.

Biomarkers 75

Biomarkers Heart Disease Diabetes Research 75

Journal of the American Heart Association

FEBRUARY 27, 2024

A group of 24 candidate biomarkers supported by prior literature was assessed at baseline and 24 weeks later. Longitudinal analyses examined the association between baseline biomarker values, measured in plasma EDTA, and the change in arterial inflammation target to background ratio. to 0.33 (likelihood ratioP=0.0005).ConclusionsA

Biomarkers 74

Biomarkers 74

Journal of Clinical Investigation - Cardiology

APRIL 1, 2024

There is unmet need for additional biomarkers to better select patients with non–small cell lung cancer (NSCLC) that are likely to benefit from immunotherapy in order to improve patient outcomes, reduce patient toxicity, and relieve the growing burden of healthcare costs.

Biomarkers 73

Biomarkers Cancer Outcomes 73

Medical Xpress - Cardiology

JANUARY 31, 2024

A collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandro, has identified kynurenine as a critical new biomarker in the quality of stored red blood cells (RBCs), a crucial step in the development of more personalized transfusions.

Biomarkers 81

Biomarkers Research 81

Med Page Today

MAY 3, 2024

(MedPage Today) -- Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults, a longitudinal cohort study in Korea showed. Over 2 years, lower baseline plasma leptin was associated with a greater.

Biomarkers 138

Biomarkers 138

Frontiers in Cardiovascular Medicine

JANUARY 31, 2024

Objective In patients with complex coronary artery disease (CAD) undergoing cardiac surgery, myocardial protection might be impaired due to microvascular obstruction, resulting in myocardial injury and subsequent biomarker release. Preoperatively, higher levels of cardiac biomarkers were found in patients with higher SYNTAX Score II.

Coronary Artery Disease 64

Coronary Artery Disease Biomarkers Outcomes 64

Nature Reviews - Cardiology

MARCH 17, 2024

In this Review, Caporali and colleagues examine the biology of these molecules and discuss the potential of non-coding RNAs for translation to the clinic as biomarkers and therapeutics in adverse cardiac remodelling leading to ischaemic heart failure.

Biomarkers 73

Biomarkers Heart Disease Heart Failure 73

Stroke Journal

MARCH 24, 2024

While researchers in the Alzheimer disease field have been working for years to establish and test blood-based biomarkers for Alzheimer disease diagnosis, prognosis, clinical therapy discovery, and early detection, blood-based biomarkers for VCID are in their infancy and also face challenges.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Cardiovascular Diabetology

MAY 6, 2024

The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.

Risk Factors 52

Risk Factors Biomarkers Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

MARCH 3, 2024

The goal of our study is to identify potential relationships between plasma biomarkers and cardiac magnetic resonance (CMR) imaging markers in patients with HFpEF. Partial least squares discriminant analysis (PLS-DA) was used to characterize CMR and biomarker variables that differentiate the subject groups into two principal components.

Preserved Ejection Fraction 64

Preserved Ejection Fraction Biomarkers Heart Failure 64

HCPLive

JANUARY 23, 2024

Wesley Mizutani, MD, discusses California's SB 496 legislation, which addresses the crucial role of biomarkers in guiding optimal drug selection to improve overall healthcare outcomes.

Biomarkers 59

Biomarkers Outcomes 59

HCPLive

FEBRUARY 28, 2024

A study from Brigham and Women's Hospital has identified 6 blood-based biomarkers that may predict cardiovascular disease risk in rheumatoid arthritis patients.

Cardiovascular Disease 59

Cardiovascular Disease Biomarkers Hospital 59

Society of Thoracic Surgeons - Surgeon

NOVEMBER 16, 2023

Webinar Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC dkaczmarek Thu, 11/16/2023 - 16:01 December 14, 2023 Part 2 of a 2-part webinar series, supported by AstraZeneca This webinar will address preoperative biomarker testing and issues around neoadjuvant immunotherapy for NSCLC. Moderators Robert E.

Biomarkers 52

Biomarkers Webinar 52

HCPLive

FEBRUARY 19, 2024

In this Lungcast segment, Spicer spoke on several treatment-specific biomarkers for lung cancer and discussed the future of lung cancer therapy.

Cancer 69

Cancer Biomarkers Research 69

Frontiers in Cardiovascular Medicine

APRIL 24, 2024

The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. BackgroundAtherosclerosis is a widespread disorder of the cardiovascular system.

Plaque 52

Plaque Biomarkers Circulation Atherosclerosis 52

Science Daily - Heart Disease

JANUARY 11, 2024

Scientists have found that two common biomarkers could predict cardiomyopathy that is otherwise undetected by conventional screenings in childhood cancer survivors.

Biomarkers 55

Biomarkers Cancer Cardiomyopathy 55

Journal of the American Heart Association

FEBRUARY 23, 2024

We aimed to evaluate the association of 3 cardiac biomarkers in combination with poststroke cognitive impairment and their prognostic significance.Methods and ResultsThis prospective study included 566 patients with ischemic stroke. 4.07) and 1.86 (1.10–3.14) 4.07) and 1.86 (1.10–3.14)

Biomarkers 45

Biomarkers Stroke Strokes Risk Factors 45

Frontiers in Cardiovascular Medicine

FEBRUARY 11, 2024

In this review, we summarize the diagnostic and prognostic tools for ICI-myocarditis, including electrocardiography, echocardiography, cardiac magnetic resonance imaging, with emphasis on circulating biomarkers.

Biomarkers 64

Biomarkers Circulation Cancer Outcomes 64

HCPLive

JANUARY 29, 2024

A systematic review of over 400 studies in type 2 diabetes reveals 13 biomarkers, including NT-proBNP and troponin-t, with potential to significantly enhance cardiovascular disease risk prediction.

Cardiovascular Disease 59

Cardiovascular Disease Biomarkers Diabetes 59

JAMA Cardiology

FEBRUARY 20, 2024

This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.

Coronary Artery Disease 56

Coronary Artery Disease Biomarkers Plaque 56

Journal of the American Heart Association

JANUARY 31, 2024

This study investigated the metabolic biomarkers associated with AF and the differences in metabolomics and associated metabolic biomarkers between paroxysmal AF (AFPA) and persistent AF.Methods and ResultsPlasma samples were prospectively collected from patients with AF and patients in sinus rhythm with negative coronary angiography.

Biomarkers 40

Biomarkers Atrial Fibrillation Arrhythmia 40

Stroke Journal

MARCH 6, 2024

BACKGROUND:The temporal ordering of biomarkers for cerebral amyloid angiopathy (CAA) is important for their use in trials and for the understanding of the pathological cascade of CAA. Stroke, Ahead of Print.

Biomarkers 40

Biomarkers Hemorrhage Stroke Strokes 40

Journal of Clinical Investigation - Cardiology

MAY 15, 2024

In this issue of the JCI, Yehya and colleagues measured 19 plasma biomarkers in 279 children over the first seven days of ARDS. Given the complexity of this clinically defined syndrome and the repeated failure of therapeutic trials, there has been an effort to identify subphenotypes of ARDS that may share targetable mechanisms of disease.

Biomarkers 52

Biomarkers Pediatrics 52

Stroke Journal

MARCH 6, 2024

Here, we aim to provide a pragmatic but evidence-based summary of the current state of potential imaging biomarkers, focusing on magnetic resonance imaging and computed tomography, which are relevant to diagnosing, estimating prognosis, monitoring vascular cognitive impairment, and incorporating our own experiences.

Biomarkers 40

Biomarkers Dementia Stroke Strokes 40

HCPLive

JANUARY 24, 2024

Interventions designed to improve mood, especially psychological therapy, may also have notable effects on C-reactive protein, fecal calprotectin, and other inflammatory biomarkers in IBD.

Biomarkers 52

Biomarkers 52

Journal of the American Heart Association

JANUARY 12, 2024

Biomarkers were measured in a median of 16 repeated samples per individual. Cluster analysis was performed to identify biomarker‐based subphenotypes in 723 patients without a repeat ACS in the first year. The temporal biomarker patterns of patients in cluster 3 were similar to those with a repeat ACS during the first year.

Biomarkers 40

Biomarkers Outcomes 40

Circulation: Heart Failure

SEPTEMBER 12, 2023

Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. Our findings suggest that among the obesity-related biomarkers studied, higher levels of leptin and CRP are independently associated with increased odds of HFpEF, with odds ratios of 1.36 (95% CI, 1.09–1.70)

Obesity 40

Obesity Biomarkers Exercise Preserved Ejection Fraction 40

HCPLive

MAY 15, 2024

The panelists explore the significance of type 2 inflammation in asthma, including its role and associated markers, while also delving into their approach to assessing patients whose asthma is triggered or worsened by allergies, examining markers beyond IgE and noting the frequency of patients presenting with asthma symptoms during allergy season without (..)

Biomarkers 52

Biomarkers 52

HeartRhythm

APRIL 30, 2024

An aggregate weighted scoring system utilising fully-customised 3D models of patient hearts, combining functional and structural biomarkers, allows the opportunity for the enhanced assessment of patient risk and outcomes.

Biomarkers 40

Biomarkers Sudden Cardiac Death Heart Disease Defibrillator 40

Circulation: Cardiovascular Quality & Outcomes

JANUARY 19, 2024

Background:Serum troponins and CK-MB (creatine kinase-MB) are readily detectable and reliable cardiac-specific biomarkers of subclinical myocardial injury. Conclusions:Comprehensive evaluations of biomarkers of myocardial injury, cTnI and CK-MB, have considerable value for predicting adverse outcomes among patients with HCM.

Biomarkers 40

Biomarkers Sudden Cardiac Death Coronary Artery Bypass Graft Cardiomyopathy 40

Stroke Journal

FEBRUARY 1, 2024

The LDA equation combining eight biomarkers was: -0.239[LPC17:0] - 1.125[TAG51:2:FA15:0] + [TAG51:2:FA18:1] + [D-glucuronic Acid] + 0.416[hsa-miR-146b-3p] + 0.082[hsa-miR-485-3p] + 0.433[hsa-miR-5010-5p] + 0.727[hsa-miR-485-5p], effectively predicting favorable outcomes.

Biomarkers 40

Biomarkers Outcomes Aneurysm Hemorrhage 40

Science Daily - Heart Disease

MAY 1, 2024

A simple blood test could allow doctors to determine whether a person may be at higher risk for stroke or cognitive decline during their lifetime, according to a new study.

Cerebrovascular Disease 95

Cerebrovascular Disease Biomarkers Stroke Strokes 95

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Background Chagas cardiomyopathy (CHCM) is the most important clinical manifestation of Chagas disease. The analysis of cardiac miRNAs may contribute to predicting the progression to CHCM in Chagas indeterminate phase and/or to the differential diagnosis for cardiomyopathy.

Circulation 84

Circulation Cardiomyopathy Biomarkers Laboratory 84

Stroke Journal

FEBRUARY 1, 2024

It also identifies a novel biomarker for ischemic strokes from atherosclerosis. This suggests the role of lymphocytic activation in strokes from intracranial and extracranial atherosclerotic disease, which may be used as a therapeutic target.

Biomarkers 40

Biomarkers Stroke Strokes Atherosclerosis 40

Medical Xpress - Cardiology

DECEMBER 20, 2023

Decreased activity of a specific signaling pathway in brain vessels was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.

Biomarkers 102

Biomarkers 102