Biomarkers in COPD
HCPLive
MAY 24, 2024
Igor Barjaktarevic, MD, PhD, provides insights on the evolving role of biomarkers in COPD, highlighting the role of eosinophils on informing treatment decisions.
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HCPLive
MAY 24, 2024
Igor Barjaktarevic, MD, PhD, provides insights on the evolving role of biomarkers in COPD, highlighting the role of eosinophils on informing treatment decisions.
HCPLive
JUNE 10, 2024
Strnad explains key findings from research presented at the EASL Congress regarding noninvasive testing and biomarkers in AATD-LD based on phase 2 fazirsiran clinical trials.
HCPLive
MAY 1, 2024
Urinary cytokines GDF-15, IL-6, and EGF significantly strengthened the predictability of IgAN prognosis and may be viable biomarker candidates for disease progression.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2024
As a result, numerous biomarkers have been investigated in an effort to identify and prevent certain diseases sooner. These biomarkers are typically linked to complications from HTX. We also highlight the relationships between each biomarker and one or more problems, as well as their applicability in routine clinical practice.
Medical Xpress - Cardiology
JANUARY 11, 2024
Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Jude lifetime cohort study (St.
Nature Reviews - Cardiology
JULY 21, 2024
Nature Reviews Cardiology, Published online: 22 July 2024; doi:10.1038/s41569-024-01060-8 In this Roadmap arising from an NHLBI workshop, Chew and colleagues explore the use of retinal imaging biomarkers for the prediction, diagnosis and monitoring of systemic cardiovascular diseases.
Med Page Today
MARCH 6, 2024
(MedPage Today) -- DENVER -- People with HIV who received semaglutide (Ozempic, Wegovy) had reduced levels of several inflammatory biomarkers associated with cardiovascular disease, a randomized controlled trial showed. After 32 weeks, interleukin.
DAIC
APRIL 22, 2024
This is an innovative platform for measuring biomarkers,” stated Dr. Karlsberg. This study highlights the value of digital biomarkers that may enable instantaneous feedback for care providers in assessing the patient. milla1cf Mon, 04/22/2024 - 15:05 April 22, 2024 — At the annual American College of Cardiology conference ( ACC.24
Medical Xpress - Cardiology
JANUARY 25, 2024
An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes.
JAMA Cardiology
APRIL 5, 2024
This cohort study explores whether a novel artificial intelligence (AI) video-based biomarker for aortic stenosis is associated with development and progression of aortic stenosis.
Science Daily - Heart Disease
MARCH 18, 2024
Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes. Coronary heart disease is a major global health problem, especially among people with type 2 diabetes.
HCPLive
JUNE 5, 2024
The key opinion leaders explore the utilization of biomarkers in guiding the treatment of severe or uncontrolled asthma, discussing the specific role of eosinophils in informing therapeutic decision-making for patients with challenging asthma cases.
Medical Xpress - Cardiology
MARCH 18, 2024
The research team investigated the predictive performance of protein biomarkers on incident CHD in individuals with and without T2D. Among middle-aged adults, individuals with type 2 diabetes (T2D) have a two to four times higher risk of developing CHD than people without T2D.
Journal of the American Heart Association
FEBRUARY 27, 2024
A group of 24 candidate biomarkers supported by prior literature was assessed at baseline and 24 weeks later. Longitudinal analyses examined the association between baseline biomarker values, measured in plasma EDTA, and the change in arterial inflammation target to background ratio. to 0.33 (likelihood ratioP=0.0005).ConclusionsA
Medical Xpress - Cardiology
JANUARY 31, 2024
A collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandro, has identified kynurenine as a critical new biomarker in the quality of stored red blood cells (RBCs), a crucial step in the development of more personalized transfusions.
Frontiers in Cardiovascular Medicine
JANUARY 31, 2024
Objective In patients with complex coronary artery disease (CAD) undergoing cardiac surgery, myocardial protection might be impaired due to microvascular obstruction, resulting in myocardial injury and subsequent biomarker release. Preoperatively, higher levels of cardiac biomarkers were found in patients with higher SYNTAX Score II.
Journal of Clinical Investigation - Cardiology
APRIL 1, 2024
There is unmet need for additional biomarkers to better select patients with non–small cell lung cancer (NSCLC) that are likely to benefit from immunotherapy in order to improve patient outcomes, reduce patient toxicity, and relieve the growing burden of healthcare costs.
Society of Thoracic Surgeons - Surgeon
MAY 23, 2024
Video 8 in 8: Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC kchalko Thu, 05/23/2024 - 09:56 In this video in the 8 in 8 Series, Dr. Dwight Owen (Ohio State University) discussed advances in biomarker testing and neoadjuvant immunotherapy for resectable non-small cell lung cancer.
Heart BMJ
MAY 10, 2024
Biomarkers have dramatically impacted the way patients with HF are evaluated and managed. The most studied biomarkers in HF are natriuretic peptides (NPs). A timely diagnosis and initiation of evidence-based treatments are key to prevent hospitalisation and improve outcomes in this population.
Stroke Journal
MARCH 24, 2024
While researchers in the Alzheimer disease field have been working for years to establish and test blood-based biomarkers for Alzheimer disease diagnosis, prognosis, clinical therapy discovery, and early detection, blood-based biomarkers for VCID are in their infancy and also face challenges.
Society of Thoracic Surgeons - Surgeon
NOVEMBER 16, 2023
Webinar Biomarker Testing and Neoadjuvant Immunotherapy for Resectable NSCLC dkaczmarek Thu, 11/16/2023 - 16:01 December 14, 2023 Part 2 of a 2-part webinar series, supported by AstraZeneca This webinar will address preoperative biomarker testing and issues around neoadjuvant immunotherapy for NSCLC. Moderators Robert E.
Nature Reviews - Cardiology
MARCH 17, 2024
In this Review, Caporali and colleagues examine the biology of these molecules and discuss the potential of non-coding RNAs for translation to the clinic as biomarkers and therapeutics in adverse cardiac remodelling leading to ischaemic heart failure.
HCPLive
MAY 31, 2024
Using available literature, the review assesses our current understanding of AATD, emerging biomarkers, and the future of drug development.
HCPLive
JANUARY 23, 2024
Wesley Mizutani, MD, discusses California's SB 496 legislation, which addresses the crucial role of biomarkers in guiding optimal drug selection to improve overall healthcare outcomes.
Frontiers in Cardiovascular Medicine
MARCH 3, 2024
The goal of our study is to identify potential relationships between plasma biomarkers and cardiac magnetic resonance (CMR) imaging markers in patients with HFpEF. Partial least squares discriminant analysis (PLS-DA) was used to characterize CMR and biomarker variables that differentiate the subject groups into two principal components.
HCPLive
FEBRUARY 28, 2024
A study from Brigham and Women's Hospital has identified 6 blood-based biomarkers that may predict cardiovascular disease risk in rheumatoid arthritis patients.
HCPLive
FEBRUARY 19, 2024
In this Lungcast segment, Spicer spoke on several treatment-specific biomarkers for lung cancer and discussed the future of lung cancer therapy.
Med Page Today
MAY 3, 2024
(MedPage Today) -- Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults, a longitudinal cohort study in Korea showed. Over 2 years, lower baseline plasma leptin was associated with a greater.
Science Daily - Heart Disease
JANUARY 11, 2024
Scientists have found that two common biomarkers could predict cardiomyopathy that is otherwise undetected by conventional screenings in childhood cancer survivors.
JAMA Cardiology
FEBRUARY 20, 2024
This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.
HCPLive
JANUARY 29, 2024
A systematic review of over 400 studies in type 2 diabetes reveals 13 biomarkers, including NT-proBNP and troponin-t, with potential to significantly enhance cardiovascular disease risk prediction.
Cardiovascular Diabetology
MAY 6, 2024
The association between iron biomarkers and cardiovascular disease risk factors (CVD-RFs) remains unclear. We aimed to (1) evaluate the cross-sectional and longitudinal associations between iron biomarkers (se.
Journal of the American Heart Association
FEBRUARY 23, 2024
We aimed to evaluate the association of 3 cardiac biomarkers in combination with poststroke cognitive impairment and their prognostic significance.Methods and ResultsThis prospective study included 566 patients with ischemic stroke. 4.07) and 1.86 (1.10–3.14) 4.07) and 1.86 (1.10–3.14)
Frontiers in Cardiovascular Medicine
FEBRUARY 11, 2024
In this review, we summarize the diagnostic and prognostic tools for ICI-myocarditis, including electrocardiography, echocardiography, cardiac magnetic resonance imaging, with emphasis on circulating biomarkers.
Journal of the American Heart Association
JANUARY 31, 2024
This study investigated the metabolic biomarkers associated with AF and the differences in metabolomics and associated metabolic biomarkers between paroxysmal AF (AFPA) and persistent AF.Methods and ResultsPlasma samples were prospectively collected from patients with AF and patients in sinus rhythm with negative coronary angiography.
Journal of Clinical Investigation - Cardiology
MAY 15, 2024
In this issue of the JCI, Yehya and colleagues measured 19 plasma biomarkers in 279 children over the first seven days of ARDS. Given the complexity of this clinically defined syndrome and the repeated failure of therapeutic trials, there has been an effort to identify subphenotypes of ARDS that may share targetable mechanisms of disease.
Frontiers in Cardiovascular Medicine
APRIL 24, 2024
The early detection of plaques by circulating biomarkers is highly clinically relevant to prevent the occurrence of major complications such as stroke or heart attacks. BackgroundAtherosclerosis is a widespread disorder of the cardiovascular system.
Stroke Journal
MARCH 6, 2024
BACKGROUND:The temporal ordering of biomarkers for cerebral amyloid angiopathy (CAA) is important for their use in trials and for the understanding of the pathological cascade of CAA. Stroke, Ahead of Print.
HCPLive
JANUARY 24, 2024
Interventions designed to improve mood, especially psychological therapy, may also have notable effects on C-reactive protein, fecal calprotectin, and other inflammatory biomarkers in IBD.
Stroke Journal
MARCH 6, 2024
Here, we aim to provide a pragmatic but evidence-based summary of the current state of potential imaging biomarkers, focusing on magnetic resonance imaging and computed tomography, which are relevant to diagnosing, estimating prognosis, monitoring vascular cognitive impairment, and incorporating our own experiences.
Circulation: Heart Failure
SEPTEMBER 12, 2023
Fasting blood samples collected at the time of the cardiopulmonary exercise test were used to assay obesity-related biomarkers. Our findings suggest that among the obesity-related biomarkers studied, higher levels of leptin and CRP are independently associated with increased odds of HFpEF, with odds ratios of 1.36 (95% CI, 1.09–1.70)
Journal of the American Heart Association
JANUARY 12, 2024
Biomarkers were measured in a median of 16 repeated samples per individual. Cluster analysis was performed to identify biomarker‐based subphenotypes in 723 patients without a repeat ACS in the first year. The temporal biomarker patterns of patients in cluster 3 were similar to those with a repeat ACS during the first year.
Circulation: Cardiovascular Quality & Outcomes
JANUARY 19, 2024
Background:Serum troponins and CK-MB (creatine kinase-MB) are readily detectable and reliable cardiac-specific biomarkers of subclinical myocardial injury. Conclusions:Comprehensive evaluations of biomarkers of myocardial injury, cTnI and CK-MB, have considerable value for predicting adverse outcomes among patients with HCM.
Stroke Journal
FEBRUARY 1, 2024
The LDA equation combining eight biomarkers was: -0.239[LPC17:0] - 1.125[TAG51:2:FA15:0] + [TAG51:2:FA18:1] + [D-glucuronic Acid] + 0.416[hsa-miR-146b-3p] + 0.082[hsa-miR-485-3p] + 0.433[hsa-miR-5010-5p] + 0.727[hsa-miR-485-5p], effectively predicting favorable outcomes.
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