HCPLive

JANUARY 31, 2025

Management focuses on optimizing respiratory and cardiac function through appropriate medication selection, oxygen therapy when indicated, and careful monitoring of both conditions to prevent deterioration.

Heart Disease 59

Heart Disease Cardiac Function Pulmonary Hypertension 59

Frontiers in Cardiovascular Medicine

JANUARY 20, 2025

Despite its known effects on cholesterol metabolism, the role of PCSK9 in cardiac function, especially post-myocardial infarction (MI), remains unclear. Cardiac function was assessed via echocardiography and isolated working heart model experiments. PCSK9 and LDL receptor levels were measured using ELISA and qRT-PCR.

Myocardial Infarction 52

Myocardial Infarction Cardiac Function Cholesterol Pharmacology 52

Frontiers in Cardiovascular Medicine

FEBRUARY 22, 2024

The purpose of the current study was to measure the efficacy of exercise on the physical ability, cardiac function and cardiopulmonary fitness of patients with AF. Meanwhile, we also do not exclude the positive effect of exercise on the improvement of cardiac function (LVEF) in patients with AF.

Cardiac Function 64

Cardiac Function Exercise Atrial Fibrillation Quality of Life 64

Journal of Cardiothoracic Surgery

JANUARY 30, 2025

This study investigates the impact of nursing interventions, guided by behavior change theory, on the recovery of cardiac function and quality of life in patients undergoing cardiac surgery with cardiopulmonar.

Quality of Life 52

Quality of Life Cardiac Function Nursing Research 52

Frontiers in Cardiovascular Medicine

JANUARY 15, 2025

It is characterized by left ventricular hypertrophy and impaired cardiac function, with forms categorized into obstructive (oHCM) and nonobstructive (nHCM). IntroductionHypertrophic cardiomyopathy (HCM) is a common genetic heart disorder. Further research is needed to confirm long-term benefits.

Cardiomyopathy 52

Cardiomyopathy Cardiac Function Research Outcomes 52

Frontiers in Cardiovascular Medicine

JUNE 12, 2025

ResultsSTDP pretreatment significantly enhanced serum SOD activity and reduced cardiac ROS levels and cardiomyocyte apoptosis. Its cardioprotective effects include reducing apoptosis, inflammation, ROS, infarction size, and arrhythmias, while improving cardiac function and tissue repair.

Ischemia 40

Ischemia Myocardial Infarction Cardiac Function Arrhythmia 40

Frontiers in Cardiovascular Medicine

FEBRUARY 26, 2025

However, it remains unclear whether MIC contributes to cardiac function impairment in patients with CHD. An increasing number of studies indicate that MIC is associated with coronary heart disease (CHD).

Heart Disease 52

Heart Disease Cardiac Function Stenosis Hospital 52

Open Heart

SEPTEMBER 13, 2024

This could facilitate the leakage of bacterial products into circulation and contribute to inflammation and adverse cardiac remodelling. We aimed to investigate gut leakage markers and their associations with inflammation, infarct size and cardiac function. to 22.44; aOR 5.05, 95% CI 1.25 to 20.43; aOR 5.67, 95% CI 1.42

Myocardial Infarction 52

Myocardial Infarction Cardiac Function Heart Failure STEMI 52

Medical Xpress - Cardiology

JANUARY 10, 2024

Inflammation of the heart muscle, also known as myocarditis, is a serious consequence of a viral infection. This can impede the heart's ability to pump blood in the long term. In a recent study, researchers of the Faculty of Medicine of the University of Freiburg have discovered a new approach for treating myocarditis.

Cardiac Function 79

Cardiac Function Research 79

American College of Cardiology

DECEMBER 10, 2024

How do N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-CTnI) predict long-term changes in cardiac structure and function in older adults?

Cardiac Function 54

Cardiac Function Article 54

Cardiovascular Diabetology

NOVEMBER 25, 2024

Diabetic cardiomyopathy (DCM) is a severe cardiovascular complication of diabetes characterized by myocardial hypertrophy, fibrosis, and impaired cardiac function. Fibroblast growth factor 21 (FGF21) has emerg.

Cardiomyopathy 98

Cardiomyopathy Diabetes Cardiac Function 98

Frontiers in Cardiovascular Medicine

APRIL 28, 2025

With the development of mesenchymal stem cell (MSC) transplantation technology, increasing research has shown that stem cell therapy and exosomes derived from these cells hold promise for repairing damaged myocardium and improving cardiac function, becoming a hot topic in clinical treatment for HF.

Heart Failure 52

Heart Failure Pharmacology Transplant Cardiac Function 52

Frontiers in Cardiovascular Medicine

MAY 19, 2025

proven effective, this digital model could address the global underutilization of cardiac rehabilitation by providing scalable, low-cost solutions, particularly in rural and resource-limited settings. In the control group, within one year after discharge, participants will receive only the current standard postoperative follow-up management.

Outpatient 52

Outpatient Quality of Life Cardiac Rehabilitation Cardiac Function 52

HeartRhythm

APRIL 17, 2024

Peripheral electrical nerve stimulation (PENS) reportedly improves cardiac function after myocardial ischemia (MI) by rebalancing the cardiac autonomic nervous system. The dynamic and continuous influence of the PENS on autonomic and cardiac functioning based on cardiac self-repair is not well understood.

Cardiac Function 40

Cardiac Function Ischemia 40

Medical Xpress - Cardiology

JANUARY 11, 2024

Jude LIFE) have revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors. Data from the St. Jude lifetime cohort study (St.

Biomarkers 116

Biomarkers Cancer Cardiac Function Cardiomyopathy 116

JAMA Cardiology

NOVEMBER 14, 2023

This post hoc analysis of the randomized Tafamidis in Transthyretin Cardiomyopathy Clinical Trial examines the effect of tafamidis vs placebo on 30-month changes in cardiac function in patients with transthyretin amyloid cardiomyopathy.

Cardiac Function 40

Cardiac Function Cardiomyopathy 40

Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

Hypertrophic cardiomyopathy (HCM) is a genetic disorder in the heart caused by variants in sarcomeric proteins that disrupt myocardial function, leading to hypercontractility, hypertrophy, and fibrosis.

Cardiomyopathy 52

Cardiomyopathy Innovation Cardiac Function Research 52

Medical Xpress - Cardiology

DECEMBER 10, 2024

The therapy increases the amount of blood the heart can pump and dramatically improves survival, in what a paper describing the results calls "an unprecedented recovery of cardiac function."

Heart Failure 97

Heart Failure Cardiac Function 97

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

Outcomes were assessed by evaluating the clinical efficacy, cardiac function, inflammatory markers, depressive symptoms, and quality of life.

Heart Failure 52

Heart Failure Quality of Life Cardiac Function Outcomes 52

Frontiers in Cardiovascular Medicine

JUNE 6, 2025

Cardiac contractility modulation (CCM) is a novel therapeutic approach that enhances myocardial contractility and reverses cardiac remodeling, thereby improving cardiac function and quality of life in patients with HFrEF.

Heart Failure 52

Heart Failure Quality of Life Blood Pressure Cardiac Function 52

Frontiers in Cardiovascular Medicine

APRIL 21, 2025

Compared to the model group, GXBD improved the activities of BNP, CK-MB, and LDH, ameliorated the general condition and cardiac function, and repaired heart damage in MI rats. GXBD decreased MDA and ROS levels, increased SOD and GSH-Px levels, and protected cardiac tissues from oxidative stress.

Pharmacology 52

Pharmacology Ischemia Cardiac Function Research 52

Circulation

NOVEMBER 11, 2024

addition, its robust performance suggests a strong potential for widespread adoption in routine cardiac evaluations. Our approach provides rapid, accurate assessments of LVID makes it an invaluable tool for cardiac function evaluation.

Cardiac Function 40

Cardiac Function Pediatrics Echocardiogram Circulation 40

Medical Xpress - Cardiology

JANUARY 19, 2024

The study, published in the journal Science Advances, identifies the first therapeutic target that can be modulated to preserve cardiac function in pulmonary hypertension, providing hope in the fight against this rare but fatal disease for which there is currently no cure.

Pulmonary 101

Pulmonary Hypertension Cardiac Function Research 101

Frontiers in Cardiovascular Medicine

MARCH 26, 2024

Introduction This study evaluated the hypothesis that vascular aging (VA) reduces ventricular contractile function and mechanical efficiency (ME) using the left ventricular pressure-volume (PV) construct. Methods A previously published in-silico computational model (CM) was modified to evaluate the hypothesis in two phases.

Cardiac Function 64

Cardiac Function Aortic Stroke Strokes 64

Open Heart

JUNE 18, 2025

Results NDLVC patients exhibited better cardiac function than those with DCM, with higher LVEF (40.1%±15.8% Follow-up lasted until May 2024, with a composite endpoint of major adverse cardiovascular events (only NDLVC patients were followed). vs 23.3%±8.8%, p<0.001). vs 64.8%, p<0.001).

Cardiomyopathy 52

Cardiomyopathy Cardiac Function Outcomes 52

HeartRhythm

APRIL 30, 2024

Catheter ablation is recommended in patients with suspected atrial fibrillation-mediated cardiomyopathy (AMC) for the recovery of cardiac function.

Atrial Fibrillation 40

Atrial Fibrillation Cardiac Function Cardiomyopathy Ablation 40

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

ObjectiveThis network meta-analysis was to compare the efficacy of different drugs on cardiac function, renal function, and clinical outcomes in patients with acute heart failure (AHF) accompanied by renal dysfunction.MethodsPubMed, EMBASE, Cochrane Library, and Web of Science were searched to screen all clinical trials of AHF between January 1st 2001 (..)

Heart Failure 52

Heart Failure Cardiac Function Outcomes 52

DAIC

JUNE 12, 2025

If unrecognized, AS can cause irreversible myocardial damage and significant deterioration in cardiac function. Early symptoms are frequently vague or absent, resulting in delayed diagnosis and treatment. The algorithm would offer a novel, AI-driven ECG solution capable of detecting moderate-to-severe aortic stenosis.

Stenosis 52

Stenosis Aortic Aortic valve Heart Valves 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

p<0.01), and was characterised by more advanced cardiac remodelling with worse indices of multi-chamber cardiac function, as quantified by strain imaging. Compared to Cluster 1, Cluster 2 demonstrated significantly worse all-cause mortality at 12 months (HR 6.3,

Aortic valve 52

Aortic valve Aortic TAVR Cardiac Function 52

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

CAMK2D-edited mice recovered cardiac function, showed improved exercise performance, and were protected from myocardial fibrosis, which was otherwise observed in injured control mice after IR. Our findings identify a potentially effective strategy for cardioprotection in response to oxidative damage.

Cardiac Function 40

Cardiac Function Ischemia Exercise Cardiovascular Disease 40

Frontiers in Cardiovascular Medicine

MARCH 14, 2025

Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric surgery, but its effect on cardiac functions remains unclear. BackgroundObesity is a global epidemic and a major risk factor for cardiovascular diseases.

Obesity 52

Obesity Blood Pressure BMI Cardiac Function 52

Cardiovascular Diabetology

NOVEMBER 4, 2024

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

Preserved Ejection Fraction 52

Preserved Ejection Fraction Cardiac Function Heart Dysfunction Heart Failure 52

Cardiovascular Diabetology

AUGUST 7, 2024

We sought to explore the underlying mechanisms in terms of structural and functional remodelling in HCM pati. The adverse prognostic impact of diabetes on hypertrophic cardiomyopathy (HCM) is poorly understood.

Cardiomyopathy 52

Cardiomyopathy Diabetes Cardiac Function Research 52

Journal of Cardiothoracic Surgery

FEBRUARY 20, 2025

The objective of this study is to examine the therapeutic efficacy of miR-133a-transfected bone marrow mesenchymal stem cells (BM-MSCs) in restoring damaged myocardium, reducing myocardial fibrosis, and improv.

Myocardial Infarction 52

Myocardial Infarction Cardiac Function Transplant Research 52

Frontiers in Cardiovascular Medicine

MARCH 7, 2024

The patient required prolonged catecholamine support owing to poor cardiac function, and heart transplantation was considered. Case presentation A 43-year-old man with a body mass index of 41 kg/m 2 was admitted to our hospital for acute heart failure due to dilated cardiomyopathy.

Heart Failure 124

Heart Failure Obesity Heart Transplant Transplant 124

Frontiers in Cardiovascular Medicine

JANUARY 15, 2025

Pre NT-proBNP level had no effect on mechanical ventilation time, CPB time, ACC time and CCU stay and cardiac function after 3 months postoperatively. ConclusionsVSD children with higher pre NT-proBNP level had longer hospital stays after surgery than those with lower level.

VSD 52

VSD Outcomes Cardiac Function Hospital 52

Frontiers in Cardiovascular Medicine

APRIL 23, 2025

ConclusionsModerate-intensity Baduanjin (3060min/session) significantly improved 6MWT distance and cardiac function parameters by LVEF, LVESD, and LVDD, etc.Systematic Review Registrationidentifier, PROSPERO registration number: (CRD42023477008). What's more, it also decreased MLHFQ (MD: 7.00, 95% CI: 9.54 to 4.45, p=0.0003, I2=79%).ConclusionsModerate-intensity

Exercise 52

Exercise Cardiovascular Disease Cardiac Function Biomarkers 52