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Dementia Mortality Tied to Olive Oil Consumption

Med Page Today

(MedPage Today) -- Higher olive oil intake was associated with a lower risk of dementia-related mortality, a prospective study of 90,000 healthcare professionals showed. Eating at least 7 g of olive oil daily -- about a half tablespoon --.

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FDA Advisory Committee Meeting to Review MDMA-Assisted Therapy for PTSD

HCPLive

Lykos Therapeutics' new drug application for MDMA plus psychiatric intervention for adults with PTSD will be the first reviewed by an FDA committee for such a therapy.

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Tenax Therapeutics Announces New U.S. Patent Covering the Use of Levosimendan in Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (PH-HFpEF)

DAIC

Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. , a Phase 3, development-stage pharmaceutical company focused on identifying, developing and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need, announced that the United States Patent and Trademark Office ( USPTO ) has granted the Company a patent covering the use of TNX-103 (oral l evosimendan ), TNX-102 (subcutaneous levosimendan), TNX-101 (IV levosimendan

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Dietary changes may treat pulmonary hypertension

Science Daily - Heart Disease

Blood vessels in the lungs aren't like the others in the body. This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. The underlying reasons for this organ-specific vessel stiffening remained a mystery until researchers made a surprising discovery about these blood vessel cells in patients with pulmonary hypertension -- they're hungry.

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Do you need to be a trained health care professional to diagnose subtle OMI on the ECG?

Dr. Smith's ECG Blog

An undergraduate (not yet in medical school) who works as an ED technician (records all EKGs, helps with procedures, takes vital signs) and who reads this blog regularly arrived at work and happened to glance down and see this previously recorded ECG on a table in the ED. It was recorded at 0530: What do you think? The young ED tech immediately suspected LAD OMI.

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Some Patients Suffered Psychiatric Issues After Ozempic Initiation

Med Page Today

(MedPage Today) -- NEW YORK CITY -- Some patients who newly started a GLP-1 receptor agonist quickly developed psychiatric symptoms, a few case reports detailed here. One case involved a female, age 42, with a history of bipolar I disorder.

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Clinical Quiz: Lp(a) Treatments and Therapeutics Considerations

HCPLive

The final in our 3-part quiz series based on the NLA's 2024 update to their 2019 scientific statement on use of lipoprotein(a) in clinical practice focuses on treatment considerations and therapeutic options for elevated Lp(a).

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Large registry data demonstrate PCI for stable CAD can be safely performed before, during or after TAVR

Medical Xpress - Cardiology

New data reveal that percutaneous coronary intervention (PCI) can be safely performed before, during, or after transcatheter aortic valve replacement (TAVR) for patients with stable coronary artery disease (CAD). The results from the analysis were presented at the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Sessions.

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Exercise, new drug class recommended for management of hypertrophic cardiomyopathy

Science Daily - Heart Disease

Experts released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The guideline reiterates the importance of collaborative decision-making with patients who have HCM and provides updated recommendations for the most effective treatment pathways for adult and pediatric patients.

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Cardiologists Float Idea of Unionization Among Ways to Protect Employee Physicians

Med Page Today

(MedPage Today) -- LONG BEACH, Calif. -- Even recognized cardiology leaders have not been immune from threats and abuse by their hospital employers, prompting an emotional discussion on worker's rights at the Society for Cardiovascular Angiography.

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Patient on Esketamine had Improved Depression, Fibromyalgia

HCPLive

Treatment-resistant depression with intranasal esketamine was linked to improvements in major depressive disorder (MDD) symptoms and fibromyalgia pain in a 40-year-old female.

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New Study Published in JACC: Heart Failure Reveals that Despite Significant Efforts to Improve Acute Heart Failure Treatment Over the Past 20 Years, Management Remains Unchanged

DAIC

Getty Images milla1cf Thu, 05/02/2024 - 10:17 May 2, 2024 — Reprieve Cardiovascular, Inc. (‘Reprieve’), a development stage company focused on pioneering an intelligent approach to acute decompensated heart failure (ADHF) treatment, today highlighted the publication of TREAT-AHF study results in JACC: Heart Failure. Heart failure (HF) is a leading cause of hospitalization in the United States.

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New study reveals age-related brain changes influence recovery after stroke

Science Daily - Stroke

A new study has revealed that areas of age-related damage in the brain relate to motor outcomes after a stroke -- a phenomenon that may be under-recognized in stroke research. The new observational study looked at the relationship between stroke recovery and white matter hyper-intensities (WMHs) -- areas of age-related damage in the brain's white matter, which represent vascular dysfunction and are known to impact cognitive functions.

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Sedentary lifestyle puts strain on young hearts

Science Daily - Heart Disease

According to a recent study, high levels of sedentary behavior and physical inactivity from childhood strain the heart in adolescence. High cardiac workload predicts heart failure and other heart diseases. In light of the findings, increasing moderate and vigorous physical activity from childhood onwards is particularly important in preventing heart diseases.

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Alzheimer's Biomarkers Linked With Plasma Leptin Levels

Med Page Today

(MedPage Today) -- Plasma leptin levels were linked with Alzheimer's disease PET pathology in cognitively unimpaired older adults, a longitudinal cohort study in Korea showed. Over 2 years, lower baseline plasma leptin was associated with a greater.

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Smokers with Lung Abnormalities More Likely to Report Severe Acute Respiratory Disease Events

HCPLive

This analysis indicates that quantitative interstitial abnormalities may indicate alterations in lung tissue processes that can result in short- and long-term consequences as far as symptoms.

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Teleflex Announces the Limited Market Release of the Wattson Temporary Pacing Guidewire

DAIC

milla1cf Mon, 05/06/2024 - 10:50 May 6, 2024 — Teleflex Incorporate , a leading global provider of medical technologies, today announced that the Wattson Temporary Pacing Guidewire limited market release has commenced at Columbia University Irving Medical Center. The first cases were performed by Dr. Tamim Nazif , Director of Clinical Research, Dr. Susheel Kodali , Professor of Medicine and Director of the Structural Heart and Valve Center , and Dr.

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Scientists identify new treatment target for leading cause of blindness

Science Daily - Stroke

Scientists report that a gene previously implicated in the development of atherosclerotic lesions in coronary arteries could be key to understanding why many people don't benefit from the most used therapy for neovascular age-related macular degeneration (AMD), a leading cause of blindness.

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Illusion of revascularization: does anyone achieve optimal revascularization during percutaneous coronary intervention?

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardial infarction was suboptimal in many patients and gave an ‘illusion of reperfusion’. In this Perspective article, the authors propose that a similar illusion of revascularization exists for contemporary percutaneous revascularization in patients with coronary artery disease and ischaemia, and identify how outco

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'Evil Personified': Nurse Gets Life Sentence for Murdering Patients With Insulin

Med Page Today

(MedPage Today) -- A Pennsylvania nurse who purposely administered lethal doses of insulin to more than 20 patients at skilled nursing facilities received a life sentence after pleading guilty to three counts of murder and other charges, the state.

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Role of Tyrosine Kinase Inhibitors and Gene Therapy in Retinal Diseases

HCPLive

Experts discuss challenges in integrating gene therapy and port delivery systems early in treating common retinal diseases while emphasizing historical challenges and safety considerations.

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Documentary Led by HonorHealth Research Institute Focuses on Injuries to Doctors and Nurses Working in Cardiology

DAIC

milla1cf Tue, 05/07/2024 - 12:54 May 7, 2024 — HonorHealth Research Institute ’s David G. Rizik , M.D., narrates and is a co-producer of a documentary focused on radiation and orthopedic injuries suffered by doctors and nurses who work in cardiac catheterization laboratories where they apply the very latest non-surgical technologies to treat the world’s leading cause of death, heart disease.

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Biomarker found to help identify cells that can repair damaged blood vessels

Science Daily - Heart Disease

Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.

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SGLT1 and SGLT2 inhibition, circulating metabolites, and cerebral small vessel disease: a mediation Mendelian Randomization study

Cardiovascular Diabetology

Sodium-glucose cotransporter 2 (SGLT2) and SGLT1 inhibitors may have additional beneficial metabolic effects on circulating metabolites beyond glucose regulation, which could contribute to a reduction in the b.

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With Help From AI, Randy Travis Got His Voice Back After Debilitating Stroke

Med Page Today

(MedPage Today) -- With some help from artificial intelligence (AI), country music star Randy Travis, celebrated for his timeless hits like "Forever and Ever, Amen" and "I Told You So," has his voice back. In July 2013, Travis was hospitalized.

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Paul Appelbaum, MD: What to Warn Patients When Prescribing Psychedelics in the Future

HCPLive

In an interview, Paul Appelbaum, MD, discussed issues clinicians will need to bring up to their patients if the FDA approves a psychedelic-assisted therapy.

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Cardiologists Train Large AI Model to Assess Heart Structure, Function

DAIC

Cedars-Sinai and Smidt Heart Institute investigators developed a novel foundation model that integrates computer vision interpretation of echocardiogram images with natural language processing to augment cardiologists’ interpretation of echocardiograms. Image by Getty. milla1cf Thu, 05/02/2024 - 10:09 May 2, 2024 — Artificial intelligence experts at Cedars-Sinai and the Smidt Heart Institute created a dataset with more than 1 million echocardiograms, or cardiac ultrasound videos, and their corre

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New York hospital halts open-heart surgeries

Becker's Hospital Review - Cardiology

Utica, N.Y.-based Wynn Hospital is temporarily suspending open-heart surgeries to review and strengthen the service, NBC affiliate WKTV reported May 7.

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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?

Cardiovascular Diabetology

Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate in type 1 diabetes infer insulin sensitivity from c.

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Medicare Drug Price Negotiation; Diagnostic Errors

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Sociodemographic Factors Linked to Topical Psoriasis Treatment Non-Adherence

HCPLive

A new study found specific sociodemographic factors were linked to 76.4% lower odds of adhering to topical therapy for psoriasis.

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DAIC's Top 10 for April

DAIC

Clinical trials and innovative technology took center stage during the month of April, racking up some record number views. Here is a look at what DAIC viewers were reading last month: 1. New Study Reveals 65 and Older Population Lowered Blood Pressure, Cholesterol and Weight Using Mobile Technology 2. Atlantic Health System’s Morristown Medical Center Treats First Patient in New Jersey with Edwards’ EVOQUE Tricuspid Valve Replacement 3.

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Exercise, New Drug Class Recommended for Management of Hypertrophic Cardiomyopathy

American Heart News - Heart News

WASHINGTON and DALLAS (May 8, 2024) – The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM). The.

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No benefit of apoA-I infusion after myocardial infarction

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 03 May 2024; doi:10.1038/s41569-024-01031-z In the AEGIS-II trial, infusion of apolipoprotein A-I to increase cholesterol efflux capacity did not improve outcomes in patients with acute myocardial infarction.

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Kids With Hypertension May Have Twice the Risk of Cardiac Events

Med Page Today

(MedPage Today) -- Children diagnosed with hypertension had a higher associated long-term risk of major adverse cardiac events (MACE) compared with matched controls without the condition, according to a Canadian population-based, retrospective.

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Discussing the Potential Approval of Tapinarof for Atopic Dermatitis with John Browning, MD

HCPLive

In this interview, Browning discusses his team’s trial data and the implications of the FDA’s decision to accept the supplemental new drug application for tapinarof as an eczema treatment.

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Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization

Cardiovascular Diabetology

In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i.

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