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Chronic Thromboembolic Pulmonary Hypertension: the therapeutic assessment

Frontiers in Cardiovascular Medicine

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.

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Dietary changes may treat pulmonary hypertension

Science Daily - Heart Disease

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death.

Pulmonary 113
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Sotatercept's FDA Approval a New Chapter for Pulmonary Arterial Hypertension

Med Page Today

(MedPage Today) -- The FDA approved sotatercept (Winrevair) for treating pulmonary arterial hypertension (PAH) in adults, Merck announced on Tuesday. A novel activin signaling inhibitor, sotatercept is indicated to increase exercise capacity.

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Hormone replacement therapy may improve pulmonary hypertension and right ventricular function

Medical Xpress - Cardiology

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.

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Reviva Announces Grant of European Patent Covering Use of Brilaroxazine for the Treatment of Pulmonary Hypertension

DAIC

“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.

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RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

Journal of Clinical Investigation - Cardiology

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

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Pulmonary artery sarcoma affecting the pulmonary valve mistaken as pulmonary vasculitis: a case report and comparative literature review

Journal of Cardiothoracic Surgery

Pulmonary arterial sarcomas (PAS) are rare aggressive tumours occurring mainly in the pulmonary trunk. We report a case of PAS involving the pulmonary trunk wall and valve, with uniform wall thickening which r.