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Sotatercept's FDA Approval a New Chapter for Pulmonary Arterial Hypertension

Med Page Today

(MedPage Today) -- The FDA approved sotatercept (Winrevair) for treating pulmonary arterial hypertension (PAH) in adults, Merck announced on Tuesday. A novel activin signaling inhibitor, sotatercept is indicated to increase exercise capacity.

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RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

Journal of Clinical Investigation - Cardiology

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

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What are the Cyanotic Congenital Heart Diseases With Decreased Pulmonary Blood Flow?

All About Cardiovascular System and Disorders

Tetralogy of Fallot TOF with pulmonary atresia Pulmonary atresia with intact interventricular septum Tricuspid atresia Double outlet right ventricle Transposition of great arteries with ventricular septal defect and pulmonary stenosis Ebstein’s anomaly of tricuspid valve In DORV and tricuspid atresia, there are also variants with increased pulmonary (..)

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Antler Sign in Pulmonary Venous Hypertension

All About Cardiovascular System and Disorders

Transcript of the video: Now we will discuss a chest X-ray showing antler sign in pulmonary venous hypertension. So, the shape of the upper lobe vessels in venous hypertension, pulmonary venous hypertension, will be resembling the antlers of the stag. For a change, first we will see the picture of a stag, with antlers.

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Aria CV Announces First Patient Successfully Implanted with Second-Generation Pulmonary Hypertension System

DAIC

milla1cf Tue, 02/27/2024 - 17:29 February 27, 2024 — Aria CV, Inc , a developer of medical devices treating pulmonary hypertension, today announced the first patient was implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial at Ascension St. Ashwin Ravichandran and Scott Hittinger.

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Mortality Reaches 20% for Hospitalized Patients With High-Risk Pulmonary Embolism

Med Page Today

(MedPage Today) -- Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT.

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Sudden Shortness of Breath - Pulmonary Embolism

ECG Guru

These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.