Science Daily - Heart Disease

AUGUST 21, 2024

A new study has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

Pulmonary 106

Pulmonary Hypertension 106

Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

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Pulmonary Hypertension 98

Medical Xpress - Cardiology

MAY 19, 2024

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.

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Pulmonary Hypertension Research 98

ECG Guru

JULY 14, 2023

These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.

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Embolism Pulmonary Tachycardia 98

DAIC

JULY 10, 2024

“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.

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Pulmonary Hypertension Pharmacology Biomarkers 111

DAIC

JANUARY 29, 2024

They looked at anonymous results for 57,531 adult patients who underwent pulmonary resection—removal of all or part of a lung—between January 2009 and June 2021. occurrence of postoperative PE in patients undergoing a first-time pulmonary resection for lung cancer. occurrence of postoperative VTE and a 1.3%

Cancer 116

Cancer Pulmonary Research Blood Clot 116

Heart BMJ

JANUARY 13, 2025

Right heart failure is the most common cause of mortality in patients with pulmonary arterial hypertension. 1 This includes chronic thromboembolic pulmonary hypertension (CTEPH), which through obstruction of the pulmonary arteries increases afterload on the right ventricle (RV), ultimately resulting in RV failure.

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Pulmonary Hypertension Angioplasty Heart Failure 98

DAIC

DECEMBER 13, 2023

Pulmonary arterial hypertension, a form of high blood pressure that occurs in the lungs, is a target of research by Cedars-Sinai investigators. Pulmonary arterial hypertension is a rare disease, affecting fewer than 100 people per million. Siegel Family Foundation Distinguished Professor and senior author of the study. “We

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Pulmonary Hypertension Blood Pressure Research 105

Med Page Today

DECEMBER 29, 2024

(MedPage Today) -- In March, we reported on back-to-back FDA approvals for two treatments in pulmonary arterial hypertension (PAH). In this report, we follow up on what has happened since. After the FDA approved both combination macitentan/tadalafil.

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Pulmonary Hypertension 84

Med Page Today

JANUARY 1, 2024

(MedPage Today) -- Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT.

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Embolism Pulmonary Hospital Outcomes 100

Medical Xpress - Cardiology

JANUARY 19, 2024

A research team has discovered a possible therapeutic target for pulmonary hypertension.

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Pulmonary Hypertension Cardiac Function Research 101

Medical Xpress - Cardiology

JULY 8, 2024

Pulmonary hypertension is a very serious disease that leads to heart failure and death in many patients.

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Pulmonary Hypertension Physiology Heart Failure 88

Journal of the American Heart Association

JANUARY 17, 2025

However, the cause and risk factors for mortality remain uncertain.MethodsThis retrospective, singlecenter study identified children with primary and secondary pulmonary vein stenosis through a cardiac catheterization database. 95% CI, 2.214.1];P<0.001). P<0.001). 95% CI, 1.610.4];P=0.004), 95% CI, 1.111.5];P=0.032),

Stenosis 76

Stenosis Pulmonary Sudden Cardiac Death Pediatrics 76

DAIC

MAY 6, 2024

Results of Tenax Therapeutics’ Phase 2 HELP study of levosimendan in patients with pulmonary hypertension (PH) with heart failure with preserved ejection fraction (HFpEF) demonstrated that I.V. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

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Preserved Ejection Fraction Heart Failure Pulmonary Hypertension 105

Science Daily - Heart Disease

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a new study.

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Pulmonary Hypertension Blood Pressure 96

Medical Xpress - Cardiology

DECEMBER 10, 2023

Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography & Interventions.

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Embolism Pulmonary 89

Medical Xpress - Cardiology

MAY 2, 2024

This difference becomes clear in pulmonary hypertension, in which only the lungs' blood vessels stiffen progressively, leading to chronic lung disease, heart failure and death. Blood vessels in the lungs aren't like the others in the body.

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Pulmonary Hypertension Heart Failure 75

Journal of Cardiothoracic Surgery

OCTOBER 31, 2024

In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.

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Pulmonary Aortic Research 80

Medical Xpress - Cardiology

MARCH 29, 2024

Food and Drug Administration has approved Winrevair (sotatercept-csrk) as an injectable treatment for pulmonary arterial hypertension (PAH) in adults.

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Pulmonary Hypertension 77

Journal of the American Heart Association

DECEMBER 24, 2024

Up to 50% of patients with pulmonary embolism (PE) experience hemodynamic instability and approximately 70% of patients who die of PE experience an accelerated cascade of symptoms within the first hours of onset of symptoms, thus necessitating rapid evaluation and intervention. Journal of the American Heart Association, Ahead of Print.

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Embolism Pulmonary Ischemia Circulation 75

Med Page Today

DECEMBER 12, 2023

(MedPage Today) -- Stable patients with pulmonary vascular disease (PVD) tolerated travel to high altitudes fairly well with frequent monitoring and supplemental oxygen therapy provided as necessary, a field study found. Despite the perceived.

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Pulmonary Hypertension 83

Open Heart

OCTOBER 1, 2024

Patients were categorised into cardiac or pulmonary origin groups based on initial admission. True cardiac origin was confirmed in 96 patients in a sensitivity analysis of 129 patients with a high probability of cardiac origin initially misdiagnosed as pulmonary origin predicted by AI-ECG.

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Pulmonary Heart Failure 98

Medical Xpress - Cardiology

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a study led by Cedars-Sinai investigators.

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Pulmonary Hypertension Blood Pressure 85

HCPLive

JANUARY 2, 2025

A recent study identified the prevalence of asymptomatic pulmonary involvement in patients with newly diagnosed RA or PsA, highlighting the need to reevaluate screening protocols.

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Pulmonary 65

HeartRhythm

NOVEMBER 7, 2024

Superior vena cava (SVC) conduction delay or isolation during right superior pulmonary vein (RSPV) ablation using thermal ablation technologies has been previously described.1,2 1,2 No reports regarding the impact of pulsed-field ablation (PFA) on the SVC exist.

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Ablation Pulmonary Technology 75

Journal of Cardiothoracic Surgery

JANUARY 2, 2024

While the role of low-dose computed tomography (CT) in lung cancer screening is established, its limitations in detailing pulmonary vascular variations are less emphasized. Three-dimensional reconstruction tec.

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Pulmonary Cancer 78

Journal of Cardiothoracic Surgery

JANUARY 4, 2025

Pulmonary artery sling (PAS) is a rare congenital anomaly where the left pulmonary artery (LPA) branches from the right pulmonary artery, compressing the trachea and esophagus and frequently leading to respira.

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Pulmonary Congenital 52

Med Page Today

JANUARY 26, 2025

(MedPage Today) -- LOS ANGELES -- For surgeons already split on their preference of inhaled pulmonary vasodilator to prevent postoperative right ventricular (RV) failure, a shifting market is not helping decision-making, as highlighted by a debate.

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HeartRhythm

JANUARY 27, 2024

However, vagal responses and reversible effects on ganglionated plexi (GP) are observed during pulmonary vein isolation (PVI). Pulsed field ablation (PFA) is selective for the myocardium. Anterior-right GP ablation has been proven to effectively prevent vagal responses during radiofrequency-based PVI.

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Pulmonary Ablation 74

DAIC

JANUARY 6, 2025

6, 2025 Medtronic plc hasannounced it received CE ( Conformit Europenne ) Mark for the Harmony Transcatheter Pulmonary Valve (TPV) System, a minimally invasive alternative to open-heart surgery for congenital heart disease patients with native or surgically repaired right ventricular outflow tract (RVOT).

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Pulmonary Congenital Heart Disease Open-Heart Surgery Congenital 52

American College of Cardiology

JANUARY 21, 2025

Acute pulmonary embolism (PE) remains a diagnostic and therapeutic challenge, with an estimated 60,000-100,000 deaths each year in the United States.

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Embolism Pulmonary Thrombolysis Article 58

Med Page Today

MAY 4, 2024

(MedPage Today) -- LONG BEACH, Calif. -- Big Data may provide some answers to the many questions surrounding advanced catheter-based pulmonary embolism (PE) therapies, a buzzing field that otherwise has little evidence from real-world practice.

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Embolism Pulmonary 67

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

Pulmonary sequestration (PS) is a rare congenital lung developmental anomaly characterized by abnormal lung tissue that receives its blood supply from the aorta. Utilizing the Seldinger technique, we accessed the right femoral artery and vein for angiography, confirming the abnormal vessels supplying the pulmonary cyst.

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Embolism Pulmonary Congenital 52

HCPLive

JANUARY 31, 2024

A recent analysis found risk factors linked to an embolism after VTE included Black race, interstitial fibrosis, advanced-stage disease, and increased operative duration.

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Risk Factors Pulmonary Embolism 105

Medical Xpress - Cardiology

JANUARY 22, 2025

A new molecular imaging technique18F-FAPI PETcan detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression.

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Pulmonary Hypertension 52

Dr. Smith's ECG Blog

JUNE 17, 2024

He was started on a heparin drip and CTA of the chest was ordered to rule out pulmonary embolism. This is a case like many others posted (see list below) and the EKG from the patient’s original presentation can be quickly recognized as diagnostic for pulmonary embolism. In fact, Kosuge et al. Accessed May 28, 2024. This is a quiz.

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Chest Pain Embolism Pulmonary Tachycardia 136

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. The actual frequency of pulmonary vein (PV) occlusion remains a topic of debate.

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Atrial Fibrillation Stenosis Pulmonary Ablation 52