Science Daily - Heart Disease

AUGUST 21, 2024

A new study has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

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Pulmonary Hypertension 119

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

Pulmonary artery sling (PAS) is an uncommon congenital anomaly in which the left pulmonary artery (LPA) originates abnormally from the posterior aspect of the right pulmonary artery (RPA). The LPA then traverses between the trachea and esophagus, resulting in compression of the lower trachea.

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Pulmonary Congenital 52

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

Pulmonary sequestration (PS) is a rare congenital lung developmental anomaly characterized by abnormal lung tissue that receives its blood supply from the aorta. Utilizing the Seldinger technique, we accessed the right femoral artery and vein for angiography, confirming the abnormal vessels supplying the pulmonary cyst.

Embolism 52

Embolism Pulmonary Congenital 52

Med Page Today

JANUARY 3, 2025

(MedPage Today) -- Despite guidelines recommending other anticoagulants for people hospitalized with acute pulmonary embolism (PE), old habits and misconceptions have kept unfractionated heparin (UFH) the initial choice for many physicians in the.

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Embolism Pulmonary Hospital 119

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. The actual frequency of pulmonary vein (PV) occlusion remains a topic of debate.

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Atrial Fibrillation Stenosis Pulmonary Ablation 52

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Chronic Thromboembolic Pulmonary Hypertension (CTEPH) is a severe and complex condition that evolves from unresolved pulmonary embolism, leading to fibrotic obstruction of pulmonary arteries, pulmonary hypertension, and potential right heart failure.

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Pulmonary Hypertension Angioplasty Pharmacology 98

Med Page Today

JANUARY 1, 2024

(MedPage Today) -- Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT.

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Embolism Pulmonary Hospital Outcomes 119

Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2025

BackgroundCurrent evidence suggests that cardiovascular disease (CVD) plays a role in the progression of chronic obstructive pulmonary disease (COPD). However, the relationship between CVD and the severity of COPD remains inadequately understood.

Cardiovascular Disease 52

Cardiovascular Disease Pulmonary BMI Hypertension 52

Journal of the American Heart Association

FEBRUARY 8, 2025

Pulmonary arterial hypertension is a disease of the pulmonary vasculature, resulting in elevated pressure in the pulmonary arteries and disrupting the physiological coordination between the right heart and the pulmonary circulation. Journal of the American Heart Association, Ahead of Print.

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Exercise Pulmonary Hypertension Quality of Life 40

Hypertension Journal

APRIL 11, 2025

BACKGROUND:Aberrant BMPR2 (bone morphogenetic protein receptor 2) signaling is associated with the pathogenesis of pulmonary hypertension. By contrast, mice with smooth muscle cell-specificSmad4deletion had no pulmonary hypertension but rather displayed evident aortic aneurysm and dissection.

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Pulmonary Hypertension Aneurysm Aortic 40

Medical Xpress - Cardiology

MAY 19, 2024

The use of hormone replacement therapy (HRT) may be associated with improved pulmonary hypertension in women, according to research presented at the ATS 2024 International Conference held May 17–22 in San Diego.

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Pulmonary Hypertension Research 98

ECG Guru

JULY 14, 2023

These are typical ECG changes that may indicate a pulmonary embolism. The patient has an acute pulmonary embolism. Sinus tachycardia may be present in acute pulmonary embolism. We see a sinus rhythm with left anterior fascicular block (LAFB) and conspicuous T-wave inversions in the inferior leads and in V1-V6.

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Embolism Pulmonary Tachycardia 98

DAIC

JULY 10, 2024

“This latest patent further secures the broad therapeutic potential of brilaroxazine for inflammatory conditions driven by underlying disruption in serotonin signaling like pulmonary hypertension,” said Laxminarayan Bhat, Ph.D. Founder, President, and CEO. Brilaroxazine has already received Orphan Drug Designation by the U.S.

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Pulmonary Hypertension Pharmacology Biomarkers 111

Journal of Clinical Investigation - Cardiology

FEBRUARY 1, 2024

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with limited treatment options. Endothelial haploinsufficiency of RAB7 caused spontaneous pulmonary hypertension (PH) in mice. Here, we explored the role of RAB7 in endothelial cell (EC) function and lung vascular homeostasis.

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Pulmonary Hypertension 98

Science Daily - Heart Disease

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a new study.

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Pulmonary Hypertension Blood Pressure 115

Med Page Today

DECEMBER 29, 2024

(MedPage Today) -- In March, we reported on back-to-back FDA approvals for two treatments in pulmonary arterial hypertension (PAH). In this report, we follow up on what has happened since. After the FDA approved both combination macitentan/tadalafil.

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Pulmonary Hypertension 98

DAIC

DECEMBER 13, 2023

Pulmonary arterial hypertension, a form of high blood pressure that occurs in the lungs, is a target of research by Cedars-Sinai investigators. Pulmonary arterial hypertension is a rare disease, affecting fewer than 100 people per million. Siegel Family Foundation Distinguished Professor and senior author of the study. “We

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Pulmonary Hypertension Blood Pressure Research 105

Med Page Today

DECEMBER 12, 2023

(MedPage Today) -- Stable patients with pulmonary vascular disease (PVD) tolerated travel to high altitudes fairly well with frequent monitoring and supplemental oxygen therapy provided as necessary, a field study found. Despite the perceived.

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Pulmonary Hypertension 104

DAIC

JANUARY 29, 2024

They looked at anonymous results for 57,531 adult patients who underwent pulmonary resection—removal of all or part of a lung—between January 2009 and June 2021. occurrence of postoperative PE in patients undergoing a first-time pulmonary resection for lung cancer. occurrence of postoperative VTE and a 1.3%

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Cancer Pulmonary Research Blood Clot 116

Frontiers in Cardiovascular Medicine

FEBRUARY 18, 2025

PDA combined with pulmonary artery aneurysm (PAA) due to IE is rare in children. Patent ductus arteriosus (PDA) is one of the most common forms of congenital heart disease (CHD). Infectious endocarditis (IE) is a rare but serious complication of PDA. In this report, we report a rare pediatric PDA case, complicated with PAA due to IE.

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Aneurysm Congenital Heart Disease Pulmonary Pediatrics 52

Medical Xpress - Cardiology

JANUARY 19, 2024

A research team has discovered a possible therapeutic target for pulmonary hypertension.

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Pulmonary Hypertension Cardiac Function Research 101

Society of Thoracic Surgeons - Adult Cardiac

JANUARY 26, 2025

During the surgery, the malfunctioning aortic valve is replaced with the patients own healthy pulmonary valvea technique called an autograftand the pulmonary valve replaced with donor tissue. Three patients underwent the Ross-Konno procedure, in which the left-sided outflow root is enlarged to fit the pulmonary autograft.

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Aortic valve Cardiothoracic Aortic Congenital 83

Medical Xpress - Cardiology

MAY 6, 2025

Patients suffering from long COVID may exhibit persistent inflammation in the heart and lungs for up to a year following SARS-CoV-2 infectioneven when standard medical tests return normal resultspotentially placing them at elevated risk for future cardiac and pulmonary conditions.

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Pulmonary Research 86

Frontiers in Cardiovascular Medicine

MAY 12, 2025

BackgroundResidual venous defects after atrial septal defect (ASD) repair may remain asymptomatic for years and can be misinterpreted as partial anomalous pulmonary venous return. She had undergone ASD repair at age 3. She underwent thoracoscopic repair with tricuspid annuloplasty.

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Pulmonary Tricuspid Anatomy 40

Medical Xpress - Cardiology

DECEMBER 10, 2023

Mechanical thrombectomy (MT) is safe and effective in real-world, high-risk patients with pulmonary embolism (PE), according to a study published online Oct. 31 in the Journal of the Society for Cardiovascular Angiography & Interventions.

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Embolism Pulmonary 89

Medical Xpress - Cardiology

APRIL 7, 2025

Pulmonary arterial hypertension (PAH) is a rare form of pulmonary hypertension. It occurs because progressive vascular changes cause the small pulmonary arteries to narrow. As a result, the right side of the heart has to pump harder to transport blood to the lungs and the blood pressure in the pulmonary circulation rises.

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Pulmonary Hypertension Blood Pressure Circulation 72

Journal of Cardiothoracic Surgery

OCTOBER 31, 2024

In our study, we aim to explore the structural differences between the aortic root and the pulmonary artery to better understand the process of pulmonary autograft dilatation during the Ross procedure.

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Pulmonary Aortic Research 80

HCPLive

JANUARY 31, 2025

Panelists discuss how the coexistence of heart disease and chronic obstructive pulmonary disease (COPD) requires careful management as these conditions significantly impact each other. Key treatable traits in COPD-associated pulmonary hypertension include hypoxemia, inflammation, and right ventricular dysfunction.

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Heart Disease Cardiac Function Pulmonary Hypertension 59

DAIC

MAY 6, 2024

Results of Tenax Therapeutics’ Phase 2 HELP study of levosimendan in patients with pulmonary hypertension (PH) with heart failure with preserved ejection fraction (HFpEF) demonstrated that I.V. Getty Images milla1cf Mon, 05/06/2024 - 10:48 May 6, 2024 — Tenax Therapeutics, Inc. ,

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Preserved Ejection Fraction Heart Failure Pulmonary Hypertension 105

HeartRhythm

MARCH 10, 2025

Pulmonary vein isolation (PVI) is the cornerstone of interventional treatment for atrial fibrillation (AF). Pulsed-field ablation (PFA), a novel non-thermal modality, was recently introduced and is now available with four different FDA-approved systems from three different manufacturers.

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Pulmonary Ablation Atrial Fibrillation 40

Med Page Today

MAY 4, 2024

(MedPage Today) -- LONG BEACH, Calif. -- Big Data may provide some answers to the many questions surrounding advanced catheter-based pulmonary embolism (PE) therapies, a buzzing field that otherwise has little evidence from real-world practice.

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Embolism Pulmonary 91

European Journal of Heart Failure

MAY 13, 2025

Meta-analysis on the main outcomes of pulmonary artery pressure (PAP)-guided management with the CardioMEMS Heart Failure (HF) System in patients with HF outside clinical trials. Effect measures are expressed as pooled means (95% CI), mean differences (95% CI), or pooled incidence rate ratios (95% CI), as appropriate.

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Heart Failure Pulmonary Quality of Life Outcomes 40

Med Page Today

JANUARY 26, 2025

(MedPage Today) -- LOS ANGELES -- For surgeons already split on their preference of inhaled pulmonary vasodilator to prevent postoperative right ventricular (RV) failure, a shifting market is not helping decision-making, as highlighted by a debate.

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Pulmonary 74

Medical Xpress - Cardiology

DECEMBER 13, 2023

Infusions of potentially therapeutic cells derived from the heart are safe for people with pulmonary arterial hypertension, a form of high blood pressure that occurs in the blood vessels of the lungs and typically affects middle-aged women, according to a study led by Cedars-Sinai investigators.

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Pulmonary Hypertension Blood Pressure 86

Open Heart

OCTOBER 1, 2024

Patients were categorised into cardiac or pulmonary origin groups based on initial admission. True cardiac origin was confirmed in 96 patients in a sensitivity analysis of 129 patients with a high probability of cardiac origin initially misdiagnosed as pulmonary origin predicted by AI-ECG.

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Pulmonary Heart Failure 98

Medical Xpress - Cardiology

MARCH 29, 2024

Food and Drug Administration has approved Winrevair (sotatercept-csrk) as an injectable treatment for pulmonary arterial hypertension (PAH) in adults.

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Pulmonary Hypertension 77

HeartRhythm

NOVEMBER 7, 2024

Superior vena cava (SVC) conduction delay or isolation during right superior pulmonary vein (RSPV) ablation using thermal ablation technologies has been previously described.1,2 1,2 No reports regarding the impact of pulsed-field ablation (PFA) on the SVC exist.

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Pulmonary Ablation Technology 75