Sat.Apr 06, 2024 - Fri.Apr 12, 2024

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Unnecessary use of beta-blockers after a heart attack?

Science Daily - Heart Disease

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily, new study suggests.

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Study Assuages Thyroid Cancer Fears With GLP-1 Receptor Agonists

Med Page Today

(MedPage Today) -- A Scandinavian cohort study suggested a popular class of diabetes drug did not put patients at an elevated risk for thyroid cancer, a longtime lingering concern with this drug class. Compared with DPP-4 inhibitors, patients.

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HeartBeam Presents Positive Results on its Artificial Intelligence Capabilities for Detecting Arrhythmias

DAIC

milla1cf Fri, 04/12/2024 - 20:53 April 12, 2024 — HeartBeam, Inc. , a medical technology company focused on transforming cardiac care through the power of personalized insights, today announced new data demonstrating that applying the company’s artificial intelligence ( AI ) algorithms to vectorcardiography (VCG) showed considerably improved performance in the detection of atrial flutter over single-lead electrocardiograms (ECGs) and similar performance to 12-lead ECGs, the standard for diagno

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Inclisiran First Strategy Safe, Effective for LDL-C Control in ASCVD Patients

HCPLive

New data from a phase 3b trial presented at ACC.24 underlines the potential of inclisiran in reducing LDL-C levels among patients with ASCVD.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Cardiology team performs novel heart artery repair with newly approved device

Science Daily - Heart Disease

Medical researchers have performed a successful transcatheter tricuspid valve repair procedure with a groundbreaking catheter.

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A young woman with chest pain, cath lab activated

Dr. Smith's ECG Blog

This case came from a friend whose sister was the patient. She knew I was interested in ECGs, so she took a photo of this one. A young woman presented with acute chest pain. This was her presenting ECG: What do you think? This is clearly Brugada phenotype. There is downsloping ST Elevation in V1 and V2. To an experienced interpreter, it is clearly not due to OMI.

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Patients with Fibromyalgia Scored Worse in Memory, Attention, Cognitive Function

HCPLive

Without controlling for the severity of symptoms, patients with either fibromyalgia or RA performed worse when compared with controls in terms of cognitive domains including verbal memory, visual memory, and strategic planning.

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A pulse of innovation: AI at the service of heart research

Science Daily - Heart Disease

Researchers unveiled BeatProfiler, a groundbreaking new tool -- a comprehensive software that automates the analysis of heart cell function from video data. It's the first system to integrate the analysis of different heart function indicators, such as contractility, calcium handling, and force output into one tool, speeding up the process significantly and reducing the chance for errors.

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Intravascular Ultrasound Outperforms Angiography for Peripheral Artery Disease Treatment

DAIC

milla1cf Thu, 04/11/2024 - 06:00 April 11, 2024 — One-year success rates from angioplasty procedures to open clogged arteries in the legs were significantly higher among patients whose procedures were guided by intravascular ultrasound (IVUS) alongside angiography compared with those whose procedures were guided by angiography alone, in a study presented at the American College of Cardiology ’s Annual Scientific Session.

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Third-Generation PCSK9 Inhibitor Cuts Cholesterol With Single, Small, Monthly Shot

Med Page Today

(MedPage Today) -- ATLANTA -- A novel PCSK9 inhibitor safely reduced LDL cholesterol levels with just a single, quick, once-monthly dose, the phase III LIBerate-HR trial showed. Lerodalcibep reduced LDL cholesterol by 56% more than placebo from.

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Alkaline Water Reduced Pain, Joint Swelling in Patients with Gout

HCPLive

Alkaline water significantly reduced VAS pain scores among patients with gout.

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Nasal spray safely treats recurrent abnormal heart rhythms, clinical trial suggests

Science Daily - Heart Disease

A clinical trial showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms. The study provides real-world evidence that a wide range of patients can safely and effectively use the experimental drug, called etripamil, to treat recurrent paroxysmal supraventricular tachycardia (PSVT) episodes at home, potentially sparing them the need for repeated hospital trips for mor

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Elder Male with Syncope

EMS 12-Lead

David Didlake @DidlakeDW EMS personnel responded to the residence of an 81 y/o Male with syncope. His spouse had called 911 after she heard a loud “thud” in the adjacent room. He was found altered, hypotensive, and with a large hematoma to the left periorbital region. No 12 Lead ECG was captured, but telemetry did reveal the following: The spouse offers a pertinent medical history to include HTN and HLD, and furthermore states that he hasn’t previously complained of any chest discomfort, or shor

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Oral Appliance for Sleep Apnea Noninferior to CPAP for Reducing Arterial BP

Med Page Today

(MedPage Today) -- ATLANTA -- An oral appliance for people with obstructive sleep apnea (OSA) was noninferior to continuous positive airway pressure (CPAP) for reducing 24-hour mean arterial blood pressure (BP) in patients with hypertension and.

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Ankeet Bhatt, MD, MBA: NUDGE-FLU Analysis in Patients With and Without Myocardial Infarction

HCPLive

Ankeet Bhatt, MD, MBA, discusses a NUDGE-FLU analysis from ACC.24 examining effect of the CV gain-framed nudge in patients with and without history of AMI.

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Heart disease, depression linked by inflammation

Science Daily - Heart Disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers have found.

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10 FDA panel members who voted on heart device connected to Abbott: Report

Becker's Hospital Review - Cardiology

The FDA convened a committee of advisers to assess a cardiac device made by Abbott, but the agency did not disclose that 10 of the 14 members had received payments from the company or conducted research it had funded, KFF Health News reported April 8.

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Impella Pump Improves Survival in STEMI-Related Cardiogenic Shock

Med Page Today

(MedPage Today) -- ATLANTA -- Routine use of the Impella CP microaxial flow pump significantly improved survival in patients with infarct-related cardiogenic shock, the randomized DanGer Shock trial showed. In more than 350 patients receiving.

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Resmetirom (Rezdiffra) Now Available in the US Pharmacies, Marks Turning Point in NASH Management

HCPLive

Madrigal Pharmaceuticals announced resmetirom is available in the US beginning on April 9, 2024, ushering in a new era of NASH management.

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Preventive angioplasty does not improve prognosis

Science Daily - Heart Disease

For heart attack patients, treating only the coronary artery that caused the infarction works just as well as preventive balloon dilation of the other coronary arteries, according to a new large study.

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Study Finds Olezarsen Cuts Triglyceride Levels by About Half

DAIC

milla1cf Sun, 04/07/2024 - 18:20 April 7, 2024 — An estimated 1 in 5 U.S. adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heart attacks and stroke. However, few treatments are currently available for this patient population, until now. A new investigational drug called olezarsen holds promise for substantially reducing triglyceride levels without significant adverse effects, accordi

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Self-Selection for Statin Appears Safe, Effective

Med Page Today

(MedPage Today) -- ATLANTA -- The vast majority of people correctly identified their own need for a statin using a web tool and took the drug appropriately without a prescription, according to an actual use study, supporting the safety of approval.

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Geographic Disparities Persist in Access to Pediatric Eye Care in US

HCPLive

The geographic distribution of pediatric optometrists and ophthalmologists substantially overlaps in the US in 2023.

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Novel CT exam reduces need for invasive artery treatment

Science Daily - Heart Disease

A new study showed that a non-invasive imaging test can help identify patients with coronary artery blockage or narrowing who need a revascularization procedure.

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Simpson Interventions Receives FDA Breakthrough Device Designation for Acolyte Image Guided Crossing and Re-Entry Catheter System

DAIC

Getty Images milla1cf Fri, 04/12/2024 - 20:55 April 12, 2024 — Simpson Interventions, Inc. , a pioneering medical technology company specializing in cardiovascular interventional devices, today announced that its groundbreaking Acolyte Image Guided Crossing and Re-Entry Catheter System has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ).

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Study reveals mechanism linking heart disease to cancer development

Medical Xpress - Cardiology

Researchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism responsible for increasing the risk of developing cancer among patients with heart disease: Small extracellular bubbles, or vesicles (sEVs), secreted from the sick heart to heal itself, are released into the bloodstream and promote the growth of cancer cells throughout the body.

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Adverse Effects of Therapeutic Psilocybin Are “Tolerable” and Resolve in 48 Hours

HCPLive

Patients on psilocybin for depression or anxiety reported tolerable adverse events, including headache, nausea, anxiety, dizziness, and elevated blood pressure.

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Researchers developed new method for detecting heart failure with a smartphone

Science Daily - Heart Disease

New technology uses a smartphone to analyze heart movement and detect heart failure.

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Study Suggests Most Patients with Acute Coronary Syndromes Can Safely Stop Aspirin One Month After Percutaneous Coronary Intervention

DAIC

milla1cf Mon, 04/08/2024 - 17:57 April 8, 2024 — People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study prese

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A 29 year old male with chest pain, ST Elevation, and very elevated troponin T

Dr. Smith's ECG Blog

By Magnus Nossen This ECG is from a young man with no risk factors for CAD, he presented with chest pain. How would you assess this ECG? How confident are you in your assessment? What is your next step? Note: lead format is Cabrera I was sent this ECG in real time. The patient is a young adult male with chest pain. The chest pain was described as pressure like and radiation to both arms and the jaw.

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No Link Between GLP-1 Drugs and Suicide, Says European Regulator

Med Page Today

(MedPage Today) -- The European Medicines Agency (EMA) found no evidence to support a causal link between GLP-1 receptor agonists and suicidal thoughts, a committee said on Friday following a 9-month review. An investigation was launched in July.

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Electrocardiographic approach strategies in patients with Parkinson disease treated with deep brain stimulation

Frontiers in Cardiovascular Medicine

Deep brain stimulation (DBS) is an interdisciplinary and reversible therapy that uses high-frequency electrical stimulation to correct aberrant neural pathways in motor and cognitive neurological disorders. However, the high frequency of the waves used in DBS can interfere with electrical recording devices (e.g., electrocardiogram, electroencephalogram, cardiac monitor), creating artifacts that hinder their interpretation.

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Novel PCSK9 Inhibitor Cut LDL Cholesterol Levels by More Than Half

DAIC

milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo. In addition, 90% of patients treated with lerodalcibep, versus 16% of those on placebo, attained the newer, more stringent guideline-recommended LDL targets set by the Amer

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Updated Clinical Data for Povetacicept in IgA Nephropathy Support Advancement to Phase 3 Trial

HCPLive

RUBY-3 findings support povetacicept’s ability to induce remission, reduce UPCR, stabilize renal function, and resolve hematuria in patients with IgAN.

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Shockwave Therapy Shows Benefit in Lower Limb Claudication

Med Page Today

(MedPage Today) -- Extracorporeal shockwave therapy may be effective for intermittent lower limb claudication in peripheral artery disease (PAD) patients unable to engage in supervised exercise or who experienced little benefit from that standard.

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Cardiovascular disease and cancer: shared risk factors and mechanisms

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 10 April 2024; doi:10.1038/s41569-024-01017-x Patients with cardiovascular disease (CVD) have an increased risk of cancer, and patients with cancer have an increased risk of CVD. In this Review, the authors discuss the shared modifiable risk factors and the shared pathophysiological mechanisms underlying the bidirectional relationship between these two prevalent diseases.