Sat.Apr 06, 2024 - Fri.Apr 12, 2024

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CDC: COVID Vax Not Linked to Sudden Deaths in Young Adults

Med Page Today

(MedPage Today) -- The hunt for a signal of excess sudden cardiac deaths among young people after COVID-19 vaccination left Oregon health officials empty-handed, they reported. Investigators searched death certificates for Oregon residents 16.

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Patients with Fibromyalgia Scored Worse in Memory, Attention, Cognitive Function

HCPLive

Without controlling for the severity of symptoms, patients with either fibromyalgia or RA performed worse when compared with controls in terms of cognitive domains including verbal memory, visual memory, and strategic planning.

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More than half a million global stroke deaths may be tied to climate change

Science Daily - Stroke

A changing climate may be linked to growing death and disability from stroke in regions around the world, according to a new study. Researchers found over three decades that non-optimal temperatures, those above or below temperatures associated with the lowest death rates, were increasingly linked to death and disability due to stroke. The study does not prove that climate change causes stroke.

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Elder Male with Syncope

EMS 12-Lead

David Didlake @DidlakeDW EMS personnel responded to the residence of an 81 y/o Male with syncope. His spouse had called 911 after she heard a loud “thud” in the adjacent room. He was found altered, hypotensive, and with a large hematoma to the left periorbital region. No 12 Lead ECG was captured, but telemetry did reveal the following: The spouse offers a pertinent medical history to include HTN and HLD, and furthermore states that he hasn’t previously complained of any chest discomfort, or shor

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Study Assuages Thyroid Cancer Fears With GLP-1 Receptor Agonists

Med Page Today

(MedPage Today) -- A Scandinavian cohort study suggested a popular class of diabetes drug did not put patients at an elevated risk for thyroid cancer, a longtime lingering concern with this drug class. Compared with DPP-4 inhibitors, patients.

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10 FDA panel members who voted on heart device connected to Abbott: Report

Becker's Hospital Review - Cardiology

The FDA convened a committee of advisers to assess a cardiac device made by Abbott, but the agency did not disclose that 10 of the 14 members had received payments from the company or conducted research it had funded, KFF Health News reported April 8.

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Ankeet Bhatt, MD, MBA: NUDGE-FLU Analysis in Patients With and Without Myocardial Infarction

HCPLive

Ankeet Bhatt, MD, MBA, discusses a NUDGE-FLU analysis from ACC.24 examining effect of the CV gain-framed nudge in patients with and without history of AMI.

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Early Win for Preemptive Stents on Vulnerable Coronary Plaque

Med Page Today

(MedPage Today) -- ATLANTA -- The concept of using stents to seal off non-flow-limiting vulnerable plaques, before they have a chance to rupture, worked out in the first major trial testing this provocative idea. Compared with standard medical.

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Intravascular Ultrasound Outperforms Angiography for Peripheral Artery Disease Treatment

DAIC

milla1cf Thu, 04/11/2024 - 06:00 April 11, 2024 — One-year success rates from angioplasty procedures to open clogged arteries in the legs were significantly higher among patients whose procedures were guided by intravascular ultrasound (IVUS) alongside angiography compared with those whose procedures were guided by angiography alone, in a study presented at the American College of Cardiology ’s Annual Scientific Session.

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Inclisiran First Strategy Safe, Effective for LDL-C Control in ASCVD Patients

HCPLive

New data from a phase 3b trial presented at ACC.24 underlines the potential of inclisiran in reducing LDL-C levels among patients with ASCVD.

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Cardiovascular disease and cancer: shared risk factors and mechanisms

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 10 April 2024; doi:10.1038/s41569-024-01017-x Patients with cardiovascular disease (CVD) have an increased risk of cancer, and patients with cancer have an increased risk of CVD. In this Review, the authors discuss the shared modifiable risk factors and the shared pathophysiological mechanisms underlying the bidirectional relationship between these two prevalent diseases.

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Oral Appliance for Sleep Apnea Noninferior to CPAP for Reducing Arterial BP

Med Page Today

(MedPage Today) -- ATLANTA -- An oral appliance for people with obstructive sleep apnea (OSA) was noninferior to continuous positive airway pressure (CPAP) for reducing 24-hour mean arterial blood pressure (BP) in patients with hypertension and.

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Cardiology Team Performs Novel Heart Artery Repair with Newly Approved Device

DAIC

Image courtesy of UC Davis Health milla1cf Tue, 04/09/2024 - 16:47 April 9, 2024 — UC Davis Health cardiology team members are among the first in the country to treat patients with tricuspid regurgitation , or a leaky heart valve, by using a groundbreaking catheter. The minimally invasive procedure, a transcatheter edge-to-edge repair (TEER), is made possible with a new medical device called the Abbott TriClip™ system.

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Extending Postpartum Medicaid Linked to Increased Perinatal Mental Health Care

HCPLive

A new study found extending postpartum Medicaid from 60 days to 12 months is linked to new mothers being more likely to seek mental health care for perinatal mood and anxiety disorders.

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Study shows effect of socio-economic factors that predict diabetic patients' risk of heart failure

Medical Xpress - Cardiology

A recent study by Case Western Reserve University used national data from U.S. military veterans with diabetes to validate and modify a widely accepted model used to predict the risk of heart failure in diabetic patients.

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Impella Pump Improves Survival in STEMI-Related Cardiogenic Shock

Med Page Today

(MedPage Today) -- ATLANTA -- Routine use of the Impella CP microaxial flow pump significantly improved survival in patients with infarct-related cardiogenic shock, the randomized DanGer Shock trial showed. In more than 350 patients receiving.

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Study Finds Olezarsen Cuts Triglyceride Levels by About Half

DAIC

milla1cf Sun, 04/07/2024 - 18:20 April 7, 2024 — An estimated 1 in 5 U.S. adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heart attacks and stroke. However, few treatments are currently available for this patient population, until now. A new investigational drug called olezarsen holds promise for substantially reducing triglyceride levels without significant adverse effects, accordi

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Adverse Effects of Therapeutic Psilocybin Are “Tolerable” and Resolve in 48 Hours

HCPLive

Patients on psilocybin for depression or anxiety reported tolerable adverse events, including headache, nausea, anxiety, dizziness, and elevated blood pressure.

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Study reveals mechanism linking heart disease to cancer development

Medical Xpress - Cardiology

Researchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism responsible for increasing the risk of developing cancer among patients with heart disease: Small extracellular bubbles, or vesicles (sEVs), secreted from the sick heart to heal itself, are released into the bloodstream and promote the growth of cancer cells throughout the body.

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Self-Selection for Statin Appears Safe, Effective

Med Page Today

(MedPage Today) -- ATLANTA -- The vast majority of people correctly identified their own need for a statin using a web tool and took the drug appropriately without a prescription, according to an actual use study, supporting the safety of approval.

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Preventive Percutaneous Coronary Intervention for High-Risk Coronary Plaques Reduces Cardiac Events

DAIC

milla1cf Thu, 04/11/2024 - 07:00 April 11, 2024 — People with a buildup of fatty atherosclerotic plaque in the heart’s arteries considered at risk of rupturing were far less likely to suffer a serious cardiac event if they underwent percutaneous coronary intervention (PCI), a procedure to open blocked arteries, compared with those who took medications alone but did not undergo PCI , according to research presented at the American College of Cardiology ’s Annual Scientific Session.

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Resmetirom (Rezdiffra) Now Available in the US Pharmacies, Marks Turning Point in NASH Management

HCPLive

Madrigal Pharmaceuticals announced resmetirom is available in the US beginning on April 9, 2024, ushering in a new era of NASH management.

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Electronic sock detects unhealthy walking style linked to cardiovascular and diabetic complications

Medical Xpress - ECG

An electronic sock that detects an unhealthy walking style linked with diabetes and poor circulation shows promise for preventing foot ulcers and amputation. The novel research is set to benefit the many patients with diabetes who have clogged arteries in the legs and is presented for the first time at EHRA 2024.

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No Link Between GLP-1 Drugs and Suicide, Says European Regulator

Med Page Today

(MedPage Today) -- The European Medicines Agency (EMA) found no evidence to support a causal link between GLP-1 receptor agonists and suicidal thoughts, a committee said on Friday following a 9-month review. An investigation was launched in July.

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TAVR Found Non-Inferior to SAVR for Low-Risk Patients

DAIC

milla1cf Thu, 04/11/2024 - 20:48 April 11, 2024 — Transcatheter aortic valve replacement (TAVR) was found to bring no increased risks and was associated with substantial decreased rates of death or stroke at one year in lowrisk patients, compared with surgical aortic valve replacement (SAVR), according to findings presented at the American College of Cardiology’s Annual Scientific Session.

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Unnecessary use of beta-blockers after a heart attack?

Science Daily - Heart Disease

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily, new study suggests.

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Acetaminophen Use During Pregnancy is Not Linked to a Child’s Risk of Autism or ADHD

HCPLive

Sibling control analyses showed acetaminophen use during pregnancy was not associated with an offspring’s risk of autism, ADHD, or intellectual disability.

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Shockwave Therapy Shows Benefit in Lower Limb Claudication

Med Page Today

(MedPage Today) -- Extracorporeal shockwave therapy may be effective for intermittent lower limb claudication in peripheral artery disease (PAD) patients unable to engage in supervised exercise or who experienced little benefit from that standard.

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Study Suggests Most Patients with Acute Coronary Syndromes Can Safely Stop Aspirin One Month After Percutaneous Coronary Intervention

DAIC

milla1cf Mon, 04/08/2024 - 17:57 April 8, 2024 — People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study prese

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Nasal spray safely treats recurrent abnormal heart rhythms, clinical trial suggests

Science Daily - Heart Disease

A clinical trial showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms. The study provides real-world evidence that a wide range of patients can safely and effectively use the experimental drug, called etripamil, to treat recurrent paroxysmal supraventricular tachycardia (PSVT) episodes at home, potentially sparing them the need for repeated hospital trips for mor

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People with Dementia and Their Care Partners Have an Increased Loneliness Risk

HCPLive

The study highlights how the experience of loneliness for care partners of people with dementia changes relationship roles throughout the dementia trajectory.

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Botulism After 'Botox'? NEJM Ignored Nazi Atrocities; Jungle Jack's Alzheimer's

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. The Tennessee Department of Health said it's collaborating with the CDC and FDA to investigate botulism-like symptoms in people who received Botox-like botulinum.

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Novel PCSK9 Inhibitor Cut LDL Cholesterol Levels by More Than Half

DAIC

milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo. In addition, 90% of patients treated with lerodalcibep, versus 16% of those on placebo, attained the newer, more stringent guideline-recommended LDL targets set by the Amer

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Heart disease, depression linked by inflammation

Science Daily - Heart Disease

Coronary artery disease and major depression may be genetically linked via inflammatory pathways to an increased risk for cardiomyopathy, a degenerative heart muscle disease, researchers have found.

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Updated Clinical Data for Povetacicept in IgA Nephropathy Support Advancement to Phase 3 Trial

HCPLive

RUBY-3 findings support povetacicept’s ability to induce remission, reduce UPCR, stabilize renal function, and resolve hematuria in patients with IgAN.

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Persistent Non-HDL-C Dyslipidemia Starting in Childhood Tied to Higher CVD Risk

Med Page Today

(MedPage Today) -- Patients with persistent non-high-density lipoprotein (HDL) cholesterol dyslipidemia from childhood to adulthood had an increased risk of cardiovascular disease (CVD) events, but those who had resolved this by adulthood had a.

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Simpson Interventions Receives FDA Breakthrough Device Designation for Acolyte Image Guided Crossing and Re-Entry Catheter System

DAIC

Getty Images milla1cf Fri, 04/12/2024 - 20:55 April 12, 2024 — Simpson Interventions, Inc. , a pioneering medical technology company specializing in cardiovascular interventional devices, today announced that its groundbreaking Acolyte Image Guided Crossing and Re-Entry Catheter System has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ).