Med Page Today
APRIL 16, 2024
(MedPage Today) -- Independent reviewers confirmed a causal relationship between the first mRNA COVID-19 vaccines and myocarditis, and also determined that, more broadly, intramuscular shots can cause a series of shoulder injuries. At the same.
Ken Grauer, MD
APRIL 13, 2024
I was sent the ECG in Figure-1 — told only that the patient was 70 years old, and had a history of an ASD ( A trial S eptal D efect ). Serum K+ was normal. The patient was hemodynamically stable with ECG #1. QUESTIONS: How would YOU interpret the rhythm in Figure-1 ? Are there P waves? Figure-1: The initial ECG in today's case. MY Initial Thoughts on Today's CASE: Knowing that today's patient has a history of an ASD ( A trial S eptal D efect ) — is relevant to the interpretation of today's inter
Journal of Clinical Investigation - Cardiology
APRIL 15, 2024
RAD54 and BLM helicase play pivotal roles during homologous recombination repair (HRR) to ensure genome maintenance. BLM amino acids (aa 181–212) interact with RAD54 and enhance its chromatin remodeling activity. Functionally, this interaction heightens HRR, leading to a decrease in residual DNA damage in colon cancer cells. This contributes to chemoresistance in colon cancer cells against cisplatin, camptothecin, and oxaliplatin, eventually promoting tumorigenesis in preclinical colon cancer mo
Medical Xpress - Cardiology
APRIL 14, 2024
New research indicates that physical activity lowers cardiovascular disease risk in part by reducing stress-related signaling in the brain.
Med Page Today
APRIL 15, 2024
(MedPage Today) -- More than one in five older adults hospitalized for respiratory syncytial virus (RSV) infection experienced an acute cardiac event, an observational study found. Among 6,248 hospitalized patients 50 or older with laboratory.
HCPLive
APRIL 19, 2024
This interview segment featured a discussion on Jay’s ACP Internal Medicine Meeting presentation ‘Advancing Equitable Approaches to Improve Obesity Care.
Dr. Smith's ECG Blog
APRIL 18, 2024
Written by Jesse McLaren A 70 year old with prior MIs and stents to LAD and RCA presented to the emergency department with 2 weeks of increasing exertional chest pain radiating to the left arm, associated with nausea. The pain recurred at rest 90 minutes prior to presentation, felt like the patient’s prior MIs, and was not relieved by 6 sprays of nitro.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Med Page Today
APRIL 18, 2024
(MedPage Today) -- Tirzepatide (Zepbound) injections reduced sleep apnea severity among patients with obesity, regardless of positive airway pressure (PAP) use, according to topline data from two phase III trials. In the SURMOUNT-OSA 1 study.
HCPLive
APRIL 18, 2024
Modern large language models perform strongly on ophthalmic knowledge assessments and approach or exceed the scores of fully qualified and trainee ophthalmologists.
DAIC
APRIL 18, 2024
Based on continuous monitoring of early recurrence of atrial tachyarrhythmia immediately after patients have undergone atrial fibrillation ablation, Musat et al. recommend shortening the blanking period from three months to one. Graphic courtesy of Dan Musat milla1cf Thu, 04/18/2024 - 13:32 April 18, 2024 — New evidence-based research calls into question the conventional three-month blanking period immediately after atrial fibrillation (AF) ablation, when early occurrences of AF are thought not
Journal of Clinical Investigation - Cardiology
APRIL 15, 2024
SARS-CoV-2 infection of the upper airway and the subsequent immune response are early, critical factors in COVID-19 pathogenesis. By studying infection of human biopsies in vitro and in a hamster model in vivo, we demonstrated a transition in nasal tropism from olfactory to respiratory epithelium as the virus evolved. Analyzing each variant revealed that SARS-CoV-2 WA1 or Delta infect a proportion of olfactory neurons in addition to the primary target sustentacular cells.
Med Page Today
APRIL 17, 2024
(MedPage Today) -- Use of antipsychotics in dementia patients was associated with an increased risk for a wider range of adverse outcomes than previously acknowledged, a population-based matched cohort study from the U.K. showed. In the analysis.
HCPLive
APRIL 19, 2024
The American College of Physicians released new recommendations for the management of type 2 diabetes with inadequate glycemic control using metformin or other first-line therapies.
DAIC
APRIL 18, 2024
Getty Images milla1cf Thu, 04/18/2024 - 13:20 April 18, 2024 — Bayer AG and Asklepios BioPharmaceutical , Inc., a gene therapy company wholly owned and independently operated as a subsidiary of Bayer AG, today announced that the U.S. Food and Drug Administration ( FDA ) has granted Fast Track Designation for the AB-1002 program. AB-1002 is an investigational one-time gene therapy that is administered to the heart with the intention of helping to promote the production of a constitutively active
Journal of Clinical Investigation - Cardiology
APRIL 15, 2024
Chromosomal instability is a prominent biological feature of myelodysplastic syndromes (MDS), with over 50% of patients with MDS harboring chromosomal abnormalities or a complex karyotype (CK). Despite this observation, the mechanisms underlying mitotic and chromosomal defects in MDS remain elusive. In this study, we identified ectopic expression of the transcription factor ONECUT3, which is associated with CKs and poorer survival outcomes in MDS.
Med Page Today
APRIL 15, 2024
(MedPage Today) -- Women who experienced major adverse pregnancy outcomes still had increased mortality risks decades later, a population-based cohort study of Swedish data found. Adverse pregnancy outcomes independently associated with increased.
Medical Xpress - Cardiology
APRIL 13, 2024
Treatment with ticagrelor alone results in a lower rate of clinically relevant bleeding compared with ticagrelor and aspirin among patients with an acute coronary syndrome who had percutaneous coronary intervention and remained event-free for one month on dual antiplatelet therapy, according to a study published online April 7 in The Lancet to coincide with the annual meeting of the American College of Cardiology, held from April 6 to 8 in Atlanta.
HCPLive
APRIL 16, 2024
The FDA approved ustekinumab-aekn for the treatment of moderate to severe plaque psoriasis and active psoriatic arthritis.
Journal of Clinical Investigation - Cardiology
APRIL 15, 2024
Craniofacial anomalies, especially midline facial defects, are among the most common birth defects in patients and are associated with increased mortality or require lifelong treatment. During mammalian embryogenesis, specific instructions arising at genetic, signaling, and metabolic levels are important for stem cell behaviors and fate determination, but how these functionally relevant mechanisms are coordinated to regulate craniofacial morphogenesis remain unknown.
Med Page Today
APRIL 19, 2024
(MedPage Today) -- Restricting daily eating to a 10-hour window was no silver bullet for boosting weight loss in people with obesity and prediabetes, a small study found. In the 12-week trial, both time-restricted eating (TRE) and a usual pattern.
Heart BMJ
APRIL 15, 2024
Objective To study the association between COVID-19 vaccination and the risk of post-COVID-19 cardiac and thromboembolic complications. Methods We conducted a staggered cohort study based on national vaccination campaigns using electronic health records from the UK, Spain and Estonia. Vaccine rollout was grouped into four stages with predefined enrolment periods.
HCPLive
APRIL 15, 2024
A recent multi-center study identified risk factors linked to premature mortality in sickle cell disease, including male gender and hematologic and biochemical parameters.
Journal of Clinical Investigation - Cardiology
APRIL 15, 2024
Loss of arterial smooth muscle cells (SMCs) and abnormal accumulation of the extracellular domain of the NOTCH3 receptor (Notch3ECD) are the 2 core features of CADASIL, a common cerebral small vessel disease caused by highly stereotyped dominant mutations in NOTCH3. Yet the relationship between NOTCH3 receptor activity, Notch3ECD accumulation, and arterial SMC loss has remained elusive, hampering the development of disease-modifying therapies.
Med Page Today
APRIL 15, 2024
(MedPage Today) -- A multi-pronged electronic health record-based population health management intervention failed to move the needle for slowing chronic kidney disease (CKD) progression, a cluster randomized trial showed. Over a median follow.
Heart BMJ
APRIL 15, 2024
Inflammation has a direct role in the development of atherosclerotic vascular disease, and oral colchicine displays broad anti-inflammatory properties. Several large, randomised controlled trials (RCTs) have evaluated colchicine’s impact on cardiovascular outcomes. Results from a meta-analysis of these trials demonstrate that colchicine reduces the risk of recurrent major adverse cardiovascular events (MACEs) by 25%, leading to its recent approval by the Food and Drug Administration for th
HCPLive
APRIL 18, 2024
Almost 50% of fibromyalgia patients use cannabis for symptom relief, according to new study. Experts suggest results underline need for clinician awareness, further research.
Dr. Smith's ECG Blog
APRIL 14, 2024
A 56 year old male with PMHx significant for hypertension had chest pain for several hours, then presented to the ED in the middle of the night. He reported chest pain that developed several hours prior to arrival and was 5/10 in intensity. The pain was located in the mid to left chest and developed after riding his bike. There was associated fatigue when symptoms developed and mild shortness of breath at onset of chest pain however that has since resolved.
DAIC
APRIL 16, 2024
Getty Images milla1cf Tue, 04/16/2024 - 12:43 April 16, 2024 — Each year more than 500,000 Americans undergo percutaneous coronary intervention , or PCI, a minimally invasive procedure to unclog the arteries that feed the heart. While PCI, which includes both angioplasty and stenting, is one of the most common operations in the world, it does carry a small (about 1-2%) but significant risk of death.
Heart Sisters
APRIL 14, 2024
Can we do a better job teaching medical and nursing students about women’s unique cardiac issues? The answer might be in these nine teaching modules!
HCPLive
APRIL 16, 2024
Mendelian randomization analysis demonstrated a direct connection between rheumatoid arthritis and an increased risk of age-related macular degeneration.
Science Daily - Heart Disease
APRIL 17, 2024
In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.
DAIC
APRIL 18, 2024
milla1cf Thu, 04/18/2024 - 13:23 April 18, 2024 — Karoo Health , the only operational provider of cardiac value-based care (VBC) enablement with published results, today launched Kohere.ai, its proprietary cloud-based platform that augments the company's proven model of care (MoC) for cardiovascular healthcare providers, payers, and patients. The Kohere.ai platform launch and 2024 roadmap are composed of the following modules: FLOW is uniquely designed and A/B tested to drive Karoo Health's MoC
Becker's Hospital Review - Cardiology
APRIL 15, 2024
Seventeen percent of cardiologists said their burnout was so severe that they may leave medicine, according to a Medscape report.
HCPLive
APRIL 18, 2024
The modified difference-in-differences analysis found notable increases in DAA use after state Medicaid programs relaxed certain coverage restrictions.
Science Daily - Heart Disease
APRIL 18, 2024
A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
DAIC
APRIL 15, 2024
Image courtesy of Abbott mtaschetta-millane Mon, 04/15/2024 - 09:54 April 15, 2024 — The U.S. Food and Drug Administration ( FDA ) announced A bbott/Thoratec Corp. is recalling HeartMate II and HeartMate 3 Left Ventricular Assist System (LVAS) due to an issue called Extrinsic Outflow Graft Obstruction , (EOGO). This occurs when biological material builds up between certain parts of the device, causing a blockage that makes it harder for the heart to pump blood.
Cardiology Update
APRIL 15, 2024
Dr. Chadi Alraies discusses the top impactful trials presented at the 2024 American College of Cardiology conference. Learn more about the highlights from ACC 2024. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram. The post ACC 2024 Highlights appeared first on Cardiology Update.
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