HCPLive

JUNE 13, 2025

Rethinking Gout in Chronic Kidney Disease Gout and chronic kidney disease (CKD) are intrinsically linked, creating a cycle of metabolic dysfunction that presents distinct diagnostic and treatment challenges. Uncontrolled Gout Demands More Than Standard Dosing, with Brittany Panico, DO Now Viewing EP: 2.

Kidney Disease 59

Kidney Disease Sickle Cell Disease CME Pediatrics 59

HCPLive

MAY 24, 2024

mg reduced major kidney disease events and slowed eGFR decline in patients with type 2 diabetes and chronic kidney disease, according to the FLOW trial. Semaglutide 1.0

Kidney Disease 116

Kidney Disease Diabetes 116

HCPLive

SEPTEMBER 18, 2024

The new guidance reviews existing tools for weight management and provides recommendations for their use in clinical practice in patients with obesity and kidney disease.

Kidney Disease 104

Kidney Disease Obesity 104

Journal of Clinical Investigation - Cardiology

OCTOBER 1, 2024

of cases, a qualifying potentially disease-causing rare variant in an established gene was found.

Kidney Disease 119

Kidney Disease Research 119

Cardiovascular Diabetology

MAY 23, 2025

Elevated blood pressure (BP) is a key contributor to the progression of arterial stiffness and the incidence of diabetic kidney disease (DKD). Cumulative BP load enables the evaluation of long-term BP exposure.

Blood Pressure 108

Blood Pressure Kidney Disease Diabetes Research 108

Heart BMJ

MAY 12, 2025

Background The impact of early-stage chronic kidney disease (CKD) on cardiovascular outcomes, particularly when albuminuria is present, remains unclear.

Kidney Disease 52

Kidney Disease Outcomes Heart Failure 52

HCPLive

MAY 18, 2024

A diagnosis of chronic kidney disease was approximately 3-times more likely in Crohn's disease than in ulcerative colitis.

Kidney Disease 111

Kidney Disease 111

Med Page Today

JUNE 9, 2025

(MedPage Today) -- Daily treatment with a mineralocorticoid receptor antagonist flopped for reducing serious cardiac events in kidney failure patients on maintenance dialysis, a randomized trial found. Among over 2,500 patients in the ACHIEVE.

Kidney Disease 68

Kidney Disease 68

HCPLive

SEPTEMBER 20, 2024

Nehad Soloman, MD, FACR; Andrew Sharobeem, DO, FACR, and Sunil Patel, MD, explore the nephrologist's vital role in gout diagnosis, treatment options for gout patients with chronic kidney disease, and strategies for managing refractory gout and its associated challenges.

Kidney Disease 105

Kidney Disease 105

Med Page Today

JUNE 5, 2025

(MedPage Today) -- An SGLT2 inhibitor combined with a nonsteroidal mineralocorticoid receptor antagonist quickly cut urinary albumin-to-creatinine ratio (UACR) in patients with albuminuria and both chronic kidney disease (CKD) and type 2 diabetes.

Diabetes 88

Diabetes Kidney Disease 88

HCPLive

FEBRUARY 2, 2024

Obesity was linked to an increased risk of focal segmental glomerulosclerosis and hypertensive nephropathy, with further analysis revealing its impact on the risk of developing end-stage kidney disease.

Kidney Disease 105

Kidney Disease Obesity Hypertension 105

HCPLive

JANUARY 23, 2024

Findings from the retrospective cohort study suggest an increased prevalence of advanced kidney disease among individuals with Crohn disease and ulcerative colitis.

Kidney Disease 105

Kidney Disease 105

Frontiers in Cardiovascular Medicine

MARCH 25, 2025

Chronic kidney disease (CKD) is a progressive condition characterized by the gradual loss of kidney function, leading to the accumulation of uremic toxins in the bloodstream. This review article explores the intricate mechanisms by which uremic toxins accelerate vascular inflammation.

Kidney Disease 52

Kidney Disease Article Risk Factors 52

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2024

BackgroundInflammation significantly impacts chronic kidney disease (CKD) and acute myocardial infarction (AMI).

Myocardial Infarction 52

Myocardial Infarction Kidney Disease Risk Factors Hospital 52

HCPLive

DECEMBER 14, 2023

Microbiota-based interventions may be a novel strategy to benefit the mitigation of chronic kidney disease advancement.

Kidney Disease 98

Kidney Disease 98

Medical Xpress - Cardiology

SEPTEMBER 17, 2024

Overactivation of the sympathetic nervous system is a hallmark sign of chronic kidney disease (CKD) that increases the risk of cardiovascular disease. People with CKD often have impaired sympathetic baroreflex sensitivity—a measure of how well the baroreflex system regulates blood pressure changes.

Kidney Disease 94

Kidney Disease Blood Pressure Cardiovascular Disease Research 94

HCPLive

MAY 17, 2024

Check out this quiz on the NKF's KDOQI recommendations on nutrition in chronic kidney disease, with a focus on their guidance for protein and energy intake!

Kidney Disease 104

Kidney Disease 104

Journal of Clinical Investigation - Cardiology

MARCH 1, 2024

Two coding variants of apolipoprotein L1 (APOL1), called G1 and G2, explain much of the excess risk of kidney disease in African Americans. While various cytotoxic phenotypes have been reported in experimental models, the proximal mechanism by which G1 and G2 cause kidney disease is poorly understood.

Kidney Disease 102

Kidney Disease 102

Medical Xpress - Cardiology

JUNE 13, 2025

SGLT2 inhibitors have become a major drug used to treat diabetes, heart failure, and chronic kidney disease. However, there have been questions as to whether it is safe to use these drugs in patients after a recent heart attack due to concerns about harming kidney function in potentially unstable patients.

Heart attacks 82

Heart attacks Heart Attack Kidney Disease Heart Failure 82

HCPLive

APRIL 17, 2024

The consensus calls for the recognition of kidney disease as a major non-communicable disease driver of premature mortality by the World Health Organization.

Kidney Disease 98

Kidney Disease 98

HCPLive

JANUARY 4, 2024

Compared to nonusers, patients with type 2 diabetes and acute kidney disease administered SGLT-2is had a significantly lower risk of mortality, major adverse kidney events, and major adverse cardiovascular events.

Kidney Disease 104

Kidney Disease Diabetes 104

American Heart News - Heart News

MARCH 21, 2024

Research Highlights: A study of nearly 4 million young adults under age 40 in South Korea found that those who had ideal cardiovascular health were nearly two-thirds less likely to develop heart disease, stroke and/or kidney disease during a 12-year.

Kidney Disease 103

Kidney Disease Heart Disease Stroke Strokes 103

HeartRhythm

FEBRUARY 6, 2025

Limited evidence supports apixaban's use for atrial fibrillation (Af) in severe chronic kidney disease (CKD) or end-stage kidney disease (ESKD) patients, where warfarin is often contraindicated.

Kidney Disease 74

Kidney Disease Atrial Fibrillation 74

Frontiers in Cardiovascular Medicine

FEBRUARY 25, 2025

Research objectiveThis study is based on bioinformatics analysis to explore the co-expressed differentially expressed genes (DEGs) between atrial fibrillation (AF) and chronic kidney disease (CKD), identify the biomarkers for the occurrence and development of the two diseases, investigate the potential connections between AF and CKD, and explore the (..)

Kidney Disease 52

Kidney Disease Atrial Fibrillation Biomarkers Download 52

Med Page Today

FEBRUARY 14, 2025

(MedPage Today) -- The dual SGLT1/2 inhibitor sotagliflozin (Inpefa) reduced the risk for myocardial infarction (MI) and stroke in high-risk patients with type 2 diabetes (T2D), chronic kidney disease (CKD), and cardiovascular risk factors, a prespecified.

Kidney Disease 83

Kidney Disease Heart attacks Heart Attack Diabetes 83

American College of Cardiology

JUNE 18, 2025

Among persons with chronic kidney disease (CKD) and type 2 diabetes (T2D), combination therapy with finerenone plus empagliflozin leads to a greater reduction in the urinary albumin-to-creatinine ratio (UACR) than either drug alone.

Kidney Disease 64

Kidney Disease Diabetes Article 64

Medical Xpress - Cardiology

DECEMBER 19, 2023

Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE.

Kidney Disease 75

Kidney Disease Heart Failure 75

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Worldwide, over 800 million people are affected by kidney disease, yet its pathogenesis remains elusive, hindering the development of novel therapeutics. Lipid accumulation and the expression of genes related to DNL were elevated in the kidneys of patients with fibrosis.

Kidney Disease 81

Kidney Disease Pharmacology Ablation 81

HCPLive

OCTOBER 26, 2024

The dapagliflozin group had an average eGFR rate of -2.24 mL/min/1.73 m2 compared to -3.67 mL/min/1.73 m2 in the control group after about 1.5 years of follow-up.

Kidney Disease 111

Kidney Disease 111

HCPLive

JULY 25, 2024

The sNDA for furosemide seeks to expand the indication to include the treatment of edema due to fluid overload in patients with CKD, with a PDUFA date of March 6, 2025.

Kidney Disease 111

Kidney Disease 111

HCPLive

JUNE 9, 2025

A recent meta-analysis reveals GLP-1 RAs significantly reduce adverse kidney outcomes, highlighting their potential in chronic kidney disease management.

Kidney Disease 76

Kidney Disease Outcomes 76

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Ten percent of the population worldwide suffers from chronic kidney disease (CKD), but the mechanisms driving CKD pathology are incompletely understood. Identify acyl-CoA synthetase short-chain family 2 (ACSS2) as a disease risk gene and demonstrate a role for ACSS2 in de novo lipogenesis (DNL).

Kidney Disease 67

Kidney Disease Pharmacology 67

HCPLive

JULY 23, 2024

Spigler provides insight into the development of new patient-focused guidelines for managing hyperkalemia in CKD and the importance of providing patients with such resources.

Kidney Disease 111

Kidney Disease Education 111

Cardiovascular Diabetology

FEBRUARY 14, 2025

People living with diabetes mellitus (DM) and chronic kidney disease (CKD) are at significantly high risk of cardiovascular events (CVEs), however the predictive performance of traditional risk prediction meth.

Kidney Disease 76

Kidney Disease Diabetes Research 76

HCPLive

JUNE 11, 2025

A panelist discusses how spironolactone is typically the first fourth medication added for resistant hypertension but has limitations in patients with kidney disease or electrolyte issues, necessitating alternative strategies like renal denervation and highlighting the need for multiple treatment approaches to avoid polypharmacy-related adherence problems. (..)

Hypertension 52

Hypertension Kidney Disease 52

HCPLive

NOVEMBER 13, 2024

People with diabetes, kidney stones, damaged joints, high uric acids, and daily use of NSAID were more likely to develop CKD than others.

Kidney Disease 105

Kidney Disease Diabetes 105

HCPLive

MARCH 5, 2025

In part 1 of this episode of Crisis Point, 3 nephrology experts and a patient advocate discuss CKDs emergence as a public health crisis.

Kidney Disease 110

Kidney Disease Public Health 110