Diagnosis of Crohn’s Disease Linked to Chronic Kidney Disease Risk
HCPLive
MAY 18, 2024
A diagnosis of chronic kidney disease was approximately 3-times more likely in Crohn's disease than in ulcerative colitis.
Kidney Disease Related Topics 
Clinical Quiz: Protein and Energy Intake in Chronic Kidney Disease from KDOQI Guidelines
HCPLive
MAY 17, 2024
Check out this quiz on the NKF's KDOQI recommendations on nutrition in chronic kidney disease, with a focus on their guidance for protein and energy intake!
International Consensus Statement Calls for Prioritization of Kidney Disease by the WHO
HCPLive
APRIL 17, 2024
The consensus calls for the recognition of kidney disease as a major non-communicable disease driver of premature mortality by the World Health Organization.
Obesity Associated With Renal Function Decline, Kidney Disease Risk
HCPLive
FEBRUARY 2, 2024
Obesity was linked to an increased risk of focal segmental glomerulosclerosis and hypertensive nephropathy, with further analysis revealing its impact on the risk of developing end-stage kidney disease.
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IgAN, Kidney Disease Common Among Patients with Inflammatory Bowel Disease
HCPLive
JANUARY 23, 2024
Findings from the retrospective cohort study suggest an increased prevalence of advanced kidney disease among individuals with Crohn disease and ulcerative colitis.
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APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease
Journal of Clinical Investigation - Cardiology
MARCH 1, 2024
Two coding variants of apolipoprotein L1 (APOL1), called G1 and G2, explain much of the excess risk of kidney disease in African Americans. While various cytotoxic phenotypes have been reported in experimental models, the proximal mechanism by which G1 and G2 cause kidney disease is poorly understood.
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In Acute Kidney Disease, SGLT2 inhibitors Were All-Around Protective
Med Page Today
JANUARY 4, 2024
(MedPage Today) -- SGLT2 inhibitors significantly lowered the risk of death, major adverse kidney events (MAKE), and major adverse cardiovascular events (MACE) in people with type 2 diabetes and acute kidney disease, according to a cohort study.
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Gut Microbiota Dysbiosis Significantly Influences Chronic Kidney Disease Progression
HCPLive
DECEMBER 14, 2023
Microbiota-based interventions may be a novel strategy to benefit the mitigation of chronic kidney disease advancement.
Targeting de novo lipogenesis to mitigate kidney disease
Journal of Clinical Investigation - Cardiology
FEBRUARY 15, 2024
Ten percent of the population worldwide suffers from chronic kidney disease (CKD), but the mechanisms driving CKD pathology are incompletely understood. Identify acyl-CoA synthetase short-chain family 2 (ACSS2) as a disease risk gene and demonstrate a role for ACSS2 in de novo lipogenesis (DNL).
SGLT-2is Mitigate Risk of Cardiovascular, Kidney Diseases in Patients with Type 2 Diabetes and AKD
HCPLive
JANUARY 4, 2024
Compared to nonusers, patients with type 2 diabetes and acute kidney disease administered SGLT-2is had a significantly lower risk of mortality, major adverse kidney events, and major adverse cardiovascular events.
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Adults younger than 40 with ideal heart health had lower heart disease, stroke, and kidney disease risk
American Heart News - Heart News
MARCH 21, 2024
Research Highlights: A study of nearly 4 million young adults under age 40 in South Korea found that those who had ideal cardiovascular health were nearly two-thirds less likely to develop heart disease, stroke and/or kidney disease during a 12-year.
Heart failure causally linked to chronic kidney disease
Medical Xpress - Cardiology
DECEMBER 19, 2023
Heart failure is causally associated with chronic kidney disease (CKD), according to a study published online Dec. 11 in PLOS ONE.
Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease
Journal of the American Heart Association
FEBRUARY 16, 2024
BackgroundInhibition of prostaglandin synthesis by nonsteroidal anti‐inflammatory drugs is associated with cardiovascular mortality and kidney disease. Future studies should address whether these associations are causal and can be targeted to improve cardiovascular and kidney outcomes.
Frail hypertensive older adults with prediabetes and chronic kidney disease: insights on organ damage and cognitive performance - preliminary results from the CARYATID study
Cardiovascular Diabetology
APRIL 9, 2024
Hypertension and chronic kidney disease (CKD) pose significant public health challenges, sharing intertwined pathophysiological mechanisms. Prediabetes is recognized as a precursor to diabetes and is often acc.
Endothelin System in Hypertension and Chronic Kidney Disease
Hypertension Journal
DECEMBER 7, 2023
ETs were shown to play important roles among others, in systemic hypertension, particularly when resistant or difficult to control, and in pulmonary hypertension, atherosclerosis, cardiac hypertrophy, subarachnoid hemorrhage, chronic kidney disease, diabetic cardiovascular disease, scleroderma, some cancers, etc.
PO-02-086 PREDICTORS OF SHOCKABLE VERSUS NON-SHOCKABLE SUDDEN CARDIAC ARREST IN PATIENTS WITH CHRONIC KIDNEY DISEASE
HeartRhythm
APRIL 30, 2024
We have recently reported that chronic kidney disease (CKD) is associated with higher likelihood of sudden cardiac arrest (SCA) presenting with non-shockable rhythms (NSR) (pulseless electrical activity/asystole), as opposed to shockable rhythms (ventricular fibrillation/pulseless ventricular tachycardia).
Kidney disease linked to increased mortality after stroke thrombolysis
Medical Xpress - Cardiology
DECEMBER 13, 2023
Renal dysfunction, especially chronic kidney disease, is the biggest risk factor of mortality among thrombolysed stroke patients, according to a retrospective cohort observational study published in Medicine.
PO-04-176 THE IMPACT OF CHRONIC KIDNEY DISEASE ON HEALTHCARE UTILIZATION AND COSTS ASSOCIATED WITH CARDIAC IMPLANTABLE ELECTRONIC DEVICE INFECTION
HeartRhythm
APRIL 30, 2024
Chronic kidney disease (CKD) increases the risk of CIED infections. Cardiac implantable electronic device (CIED) infections are a burden to hospitals and costly for health care systems. CKD may also have an impact on the severity of the infection and hospitalization.
Tricuspid Regurgitation Velocity Linked to Cerebrovascular, Kidney Disease in SCD
HCPLive
APRIL 26, 2024
A higher TRV was significantly associated with cerebrovascular disease and persistent albuminuria in children with SCD across two large cohorts.
The Critical Role of RAASi Therapy in Chronic Kidney Disease, with Wei Ling Lau, MD
HCPLive
MAY 18, 2024
Wei Ling Lau, MD, explains the importance of medication adherence to maximize the benefits of RAASi therapy.
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Efficacy and Safety of Aldosterone Synthase Inhibition With and Without Empagliflozin for Chronic Kidney Disease
American College of Cardiology
JANUARY 11, 2024
The goal of the ASi in CKD trial was to determine the effect on albuminuria of BI 690517, an investigational aldosterone synthase inhibitor, alone and in combination with empagliflozin compared with placebo in patients with chronic kidney disease (CKD).
Hemoglobin Levels Predict Renal Outcomes in Diabetic Kidney Disease
HCPLive
MARCH 26, 2024
A study in China identified a negative and non-linear relationship between hemoglobin levels and a renal composite end point in patients with DKD.
Association of long-term triglyceride-glucose index patterns with the incidence of chronic kidney disease among non-diabetic population: evidence from a functional community cohort
Cardiovascular Diabetology
JANUARY 2, 2024
The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and previous studies have confirmed the association of TyG index with incident chronic kidney disease (CKD). However, t.
Associations Between Life's Essential 8 and Chronic Kidney Disease
Journal of the American Heart Association
DECEMBER 8, 2023
BackgroundChronic kidney disease (CKD) is closely associated with cardiovascular disease. Journal of the American Heart Association, Ahead of Print.
BMI in Late Adolescence Linked to Early Chronic Kidney Disease
HCPLive
DECEMBER 14, 2023
These results highlight the potential of preventing increasing CKD burden and of preventing subsequent cardiovascular conditions, especially given current rates of obesity among adolescents.
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Cardiovascular risk and renal injury profile in subjects with type 2 diabetes and non-albuminuric diabetic kidney disease
Cardiovascular Diabetology
DECEMBER 12, 2023
In the last years, the classical pattern of diabetic kidney disease (DKD) has been partially overcome, because of the uncovering of a new DKD phenotype with significant renal dysfunction without presence of al.
Severity and Remission of Metabolic Dysfunction–Associated Fatty/Steatotic Liver Disease With Chronic Kidney Disease Occurrence
Journal of the American Heart Association
FEBRUARY 23, 2024
MAFLD/MASLD was defined as hepatic steatosis combined with metabolic dysfunction and MASLD further excluded alcohol or other causes of liver disease. Chronic kidney disease (CKD) was defined as estimated glomerular filtration rate<60 mL/min per 1.73 Hepatic steatosis was diagnosed by ultrasound.
Association of systemic in?ammation response index with all-cause mortality as well as cardiovascular mortality in patients with chronic kidney disease
Frontiers in Cardiovascular Medicine
FEBRUARY 27, 2024
Background Chronic Kidney Disease (CKD) stands as a formidable health challenge, recognized not only for its growing prevalence but also for its association with elevated mortality rates. Emerging evidence suggests that CKD is inherently linked to inflammatory processes, marking it as an inflammatory disorder.
Abstract TP292: Chronic Kidney Disease Exacerbates Post-Stroke Cell Death and Inflammatory Mechanisms
Stroke Journal
FEBRUARY 1, 2024
Chronic kidney disease (CKD) is an important independent risk factor for stroke. Stroke, Volume 55, Issue Suppl_1 , Page ATP292-ATP292, February 1, 2024. To understand the mechanisms of CKD that exacerbates stroke pathogenesis, we developed a rodent CKD model by feeding adult C57BL/6 mice with adenine.
Associations between cardiometabolic indices and the risk of diabetic kidney disease in patients with type 2 diabetes
Cardiovascular Diabetology
APRIL 24, 2024
This study was designed to assess the associations between emerging cardiometabolic indices—the atherogenic index of plasma (AIP), the stress hyperglycemia ratio (SHR), the triglyceride-glucose (TyG) index, an.
Structural Racism Linked to Increased Prevalence of Kidney Disease, Diabetes, & Cardiovascular Disease
HCPLive
DECEMBER 21, 2023
A new study is raising awareness around the effects of structural racism on the prevalence of chronic health conditions.
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Enhancing Cardiovascular Health in End-Stage Kidney Disease, with Maya N. Clark-Cutaia, PhD, RN
HCPLive
MAY 16, 2024
Clark-Cutaia, PhD, ACNP-BC, RN, highlights strategies to improve cardiovascular disease-related outcomes in patients with ESKD.
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Insulin sensitivity estimates and their longitudinal association with coronary artery disease in type 1 diabetes. Does it matter?
Cardiovascular Diabetology
MAY 2, 2024
Insulin resistance and chronic kidney disease are both associated with increased coronary artery disease risk. Many formulae estimating glucose disposal rate in type 1 diabetes infer insulin sensitivity from c.
Prognostic Value of Nighttime Double Product in Nondialysis Chronic Kidney Disease With Hypertension
Journal of the American Heart Association
DECEMBER 18, 2023
BackgroundBoth nighttime systolic blood pressure and pulse rate are associated with adverse outcomes in patients with chronic kidney disease (CKD). Journal of the American Heart Association, Ahead of Print.
Diabetes Dialogue: FLOW Trial and Chronic Kidney Disease Updates, with Brendon Neuen, MBBS, PhD
HCPLive
MARCH 21, 2024
In this episode, Neuen talks about the FLOW trial, the concept of 4 pillars of GDMT for CKD in type 2 diabetes, and how to approach sequencing of these therapies.
America’s CKM Syndrome Problem
CardiacWire
MAY 8, 2024
A new JAMA study revealed that a shocking 90% of US adults are at risk of developing cardiovascular-kidney-metabolic (CKM) syndrome, underscoring the need for preventative action before we face a wave of CKM-related heart disease. Stage 4 (heart disease, with or without kidney disease) – 9.2%
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Abstract WP159: Chronic Kidney Disease and Risk of Intracerebral Hemorrhage: The Role of Hypertension as a Mediator
Stroke Journal
FEBRUARY 1, 2024
Introduction:Chronic kidney disease (CKD) is a well-established risk factor for spontaneous intracerebral hemorrhage (ICH). Stroke, Volume 55, Issue Suppl_1 , Page AWP159-AWP159, February 1, 2024. However, the biological pathway underlying this association remains unclear.
Treatment and Control of Hypertension Among Adults With Chronic Kidney Disease, 2011 to 2019
Hypertension Journal
SEPTEMBER 14, 2023
BACKGROUND:Hypertension frequently accompanies chronic kidney disease (CKD) as etiology and sequela. Hypertension, Volume 80, Issue 12 , Page 2533-2543, December 1, 2023.
Initiation patterns of anticoagulants for atrial fibrillation among older UK adults with and without chronic kidney disease, 2010-2020
Open Heart
JANUARY 31, 2024
Background There is a paucity of data on the initiation patterns of anticoagulants among older atrial fibrillation patients with and without chronic kidney disease (CKD).
Safety of continuing mineralocorticoid receptor antagonist treatment in patients with heart failure with reduced ejection fraction and severe kidney disease: data from Swedish Heart Failure Registry
European Journal of Heart Failure
OCTOBER 18, 2023
Mineralocorticoid receptor antagonist (MRA) use in severe chronic kidney disease and heart failure with reduced ejection fraction (HFrEF). CI, confidence interval; eGFR, estimated glomerular filtration rate; HR, hazard ratio.
Clinical Quiz: Nutritional Assessment in CKD from KDOQI Guidelines
HCPLive
MAY 15, 2024
Check out this quiz on the NKF's KDOQI recommendations on nutrition in chronic kidney disease, with a focus on their guidance for nutritional assessments!
Dialysis Modality and Incident Stroke Among Patients With End-Stage Kidney Disease: A Registry-Based Cohort Study
Stroke Journal
OCTOBER 10, 2023
BACKGROUND:Patients with end-stage kidney disease undergoing dialysis are at significant risk of stroke. Whether dialysis modality is associated with cerebrovascular disease is unclear. Stroke, Volume 54, Issue 12 , Page 3054-3063, December 1, 2023.
Multidisciplinary Team Intervention Flops for Improving CKD Outcomes
Med Page Today
APRIL 15, 2024
(MedPage Today) -- A multi-pronged electronic health record-based population health management intervention failed to move the needle for slowing chronic kidney disease (CKD) progression, a cluster randomized trial showed. Over a median follow.
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EHR Alerts Trigger Primary Care Clinics to Improve Hypertension Care in CKD
Med Page Today
MARCH 15, 2024
(MedPage Today) -- A computerized clinical decision support (CDS) tool for primary care helped lower blood pressure (BP) in patients with chronic kidney disease (CKD) and uncontrolled hypertension, a cluster-randomized trial found. When primary.
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