Sat.Jan 20, 2024 - Fri.Jan 26, 2024

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Analysis finds biomarkers that improve prediction accuracy of cardiovascular disease risk in people with type 2 diabetes

Medical Xpress - Cardiology

An international academic consortium has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis, conducted by 23 experts from 11 countries, was led by The Johns Hopkins University in the United States, the Chinese University of Hong Kong in Hong Kong, and Lund University in Sweden.

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More than half of U.S. adults don’t know heart disease is leading cause of death, despite 100-year reign

American Heart News - Heart News

Highlights: More than half (51%) of respondents in a 2023 Harris Poll survey conducted on behalf of the American Heart Association did not identify heart disease as the leading cause of death in the U.S. According to the 2024 Heart Disease and Stroke.

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Ibuprofen Fails Another Crack at Reducing Preemie Lung Issues and Deaths

Med Page Today

(MedPage Today) -- Ibuprofen again failed to improve short-term outcomes when used to close patent ductus arteriosus (PDA) in newborns, the placebo-controlled Baby-OSCAR trial showed. Administered parenterally a few days after infants were born.

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Heart transplantation and biomarkers: a review about their usefulness in clinical practice

Frontiers in Cardiovascular Medicine

Advanced heart failure (AdvHF) can only be treated definitively by heart transplantation (HTx), yet problems such right ventricle dysfunction (RVD), rejection, cardiac allograft vasculopathy (CAV), and primary graft dysfunction (PGD) are linked to a poor prognosis. As a result, numerous biomarkers have been investigated in an effort to identify and prevent certain diseases sooner.

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Harnessing skin cancer genes to heal hearts

Medical Xpress - Cardiology

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

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Targeted scientific research projects to demonstrate effectiveness of ‘food is medicine’ in health care

American Heart News - Heart News

DALLAS, Jan. 24, 2024 — In an effort to identify effective food is medicine approaches for incorporating healthy food into health care delivery, the American Heart Association, the world’s leading voluntary organization focused on heart and brain health.

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Breast Cancer Drug Repurposed for Infant With Congenital Hyperinsulinism

Med Page Today

(MedPage Today) -- A 4-month-old with congenital hyperinsulinism responded well to off-label treatment with a breast cancer drug, researchers reported. A newborn presented with severe congenital hyperinsulinism due to homozygous deletion of the.

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Premature Mortality Gap Persists Among Patients with Gout

HCPLive

Mortality risks in gout have not improved in the United States in the past 3 decades, with a similar risk found among contemporary cases of gout in the United Kingdom.

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National retailers support heart and stroke health through annual Life is Why™ campaign

American Heart News - Heart News

DALLAS, Jan. 25, 2024 — This February, during American Heart Month and the American Heart Association’s Centennial year, the Association is devoted to a world of healthier lives for all by teaming up with retailers and brands around the country for Life.

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Can the Eye Reveal Cardiac and Lung Disease -- Plus Much More?

Med Page Today

(MedPage Today) -- Thinner retinal layers were associated with a long list of major diseases, including pulmonary and cardiac disorders, according to a phenotypic and genomic analysis. Among the many diseases, each standard deviation of thinner.

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Lipoprotein(a)’s Outsized Per-Particle Risks

CardiacWire

A pair of JACC studies laid what might be a new scientific foundation for all that research showing that people with high lipoprotein(a) have elevated cardiovascular risks. The first study analyzed 502k UK Biobank participants , identifying two clusters of genetic variants that either raise apoB by increasing Lp(a) or LDL, showing that the Lp(a) cluster faced far greater cardiovascular risks: Each 50 nmol/L higher Lp(a)-apoB brought a 28% greater risk for coronary heart disease, versus 4% with L

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Most US Adults Fail to Recognize Heart Disease as Leading Killer of Americans, Study Finds

HCPLive

The American Heart Association's annual report on heart disease and stroke statistics for 2024 sheds new light on the impact and level of public education surrounding the impact of heart disease and stroke in the US and abroad.

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Potassium-enriched salt is the missing ingredient in hypertension guidelines, say experts

Medical Xpress - Cardiology

A call to include recommendations on low-sodium potassium-enriched salt in hypertension treatment guidelines has been made by an international group of experts in the journal Hypertension.

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Increase in Congenital Syphilis; Decrease in Breast Cancer Mortality

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Top 103 hospitals for cardiology, per Healthgrades

Becker's Hospital Review - Cardiology

Discover the top 103 hospitals nationwide for exceptional cardiology care, recognized by Healthgrades' "America's Best Hospitals" awards.

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Anxiety, Depression Symptoms Increase Post-Dobbs Abortion Decision

HCPLive

Respondents in trigger states had significantly greater increased anxiety and depression symptoms following the Dobbs abortion decision on June 24, 2022 than respondents in non-trigger states.

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Association found between dark chocolate consumption, reduced risk of essential hypertension

Medical Xpress - Cardiology

A team of cardiologists at Shaoxing People's Hospital, working with a colleague from Zhuji People's Hospital, both in China, has found an association between consumption of dark chocolate and reductions in the risk of essential hypertension.

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ECG #413 — A Pre-Op ECG in an ASx Patient

Ken Grauer, MD

I was sent the tracing shown in Figure-1 — told only that this was a preoperative ECG obtained from an asymptomatic older woman scheduled for non-cardiac surgery. How would YOU interpret this ECG? Would you approve her for surgery if the procedure was nonemergent? Figure-1: Preoperative ECG from an asymptomatic older woman scheduled for non-cardiac surgery.

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Childhood relationships, experiences may have good and bad effects on adult heart health

American Heart News - Heart News

Research Highlights: Positive, warm relationships between caregiver and child were associated with higher odds of attaining ideal heart health at multiple points across a 20-year span of adulthood. Meanwhile, experiencing childhood adversity such as.

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Childhood Adversity May Increase Poor Heart Health Risk in Adulthood

HCPLive

Childhood trauma may decrease the likelihood of optimal heart health in adulthood, while stable and nurturing experiences are shown to promote heart health.

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Dapagliflozin and Mode of Death in Heart Failure With Improved Ejection Fraction

JAMA Cardiology

This post hoc analysis of a randomized clinical trial evaluates the association of dapagliflozin with cause-specific deaths in patients with heart failure with improved ejection fraction.

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Global Trends in Cardiovascular Diseases: Insights from the 2023 Almanac

Cardiology Update

In 2020, a collaboration involving the Journal of the American College of Cardiology (JACC), the National Heart, Lung, and Blood Institute (NHLBI), and the Institute for Health Metrics and Evaluation (IHME) was formed to focus on CVD trends. The 2023 Almanac results derived from the Global Burden of Disease (GBD) and spanning 1990 to 2022, were recently published in the Journal of American College of Cardiology.

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EM Quick Hits 54 Button Battery Ingestion, C. difficile, ECG in Tox, Bed Bugs, Fibrinogen in Trauma, Cold Air for Croup

ECG Cases

Olivia Ostrow on the management of button battery ingestions, Brit Long on C difficile infection, Jesse McLaren on an approach to ECG's in the tox patient, Joe Mullally on the identification and treatment of bed bug bites, Andrew Petrosoniak on fibrinogen replacement in bleeding trauma patients, Justin Morganstern on Cold Air for Croup. The post EM Quick Hits 54 Button Battery Ingestion, C. difficile, ECG in Tox, Bed Bugs, Fibrinogen in Trauma, Cold Air for Croup appeared first on Emergency Medi

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Energy Drinks Linked to Poor Sleep Quality, Insomnia Among College Students

HCPLive

Male college students were found to consume more energy drinks than female college students, and they had a greater risk for a short sleep duration due to energy drink consumption.

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Spotlight on Advancements in Mitral Valve Repair, Research

DAIC

You may not know Carol Barr, but in the future, she could save your life. Barr’s death at 39 from sudden cardiac arrest was caused by mitral valve prolapse—a heart valve defect that can affect the heart’s ability to pump blood. It can, in some cases, lead to death. Now, thanks to the cardiovascular advances in research and Opportunities Legacy (CAROL) Act—legislation named in honor of Barr that allocates funding through the National Heart, Lung, and Blood Institute to study heart valve disease

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More than half of US adults don't know heart disease is leading cause of death, despite 100-year reign

Science Daily - Heart Disease

More than half (51%) of respondents in a 2023 Harris Poll survey conducted on behalf of the American Heart Association did not identify heart disease as the leading cause of death in the U.S. Heart disease has been the leading cause of death in the U.S. for 100 years. Heart disease along with stroke, which is the fifth leading cause of death, claimed more lives in 2021 in the U.S. than all forms of cancer and chronic lower respiratory disease combined.

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Researchers uncover new signaling pathway in the development of atherosclerosis

Medical Xpress - Cardiology

Atherosclerosis, a chronic inflammatory disease of the inner walls of blood vessels, is responsible for many cardiovascular conditions. Dendritic cells, which act to recognize foreign substances in the body and mount an immune response, play an important role in the disease. They produce the signaling protein CCL17, a chemokine, which influences the activity and mobility of T cells, which track down infected cells in the body and attack the pathogens.

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Central Obesity Potentially Linked to Hyperuricemia, Gout

HCPLive

After adjusting for confounders, data revealed higher levels of obesity indices were linked with a gradual and dose-dependent increase in urate levels.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heart attack or myocardial infarction (MI), stroke, and cardiovascu

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“Did that go okay?” How to tell if your message is landing

Heart Sisters

"We all want the words we use publicly to be heard, understood and maybe even remembered."~ Carrie Fox :3 ways my public speaking skills evolved after my heart attack.

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Team develops bioengineered material to rapidly stop bleeding in patients on blood thinners

Medical Xpress - Cardiology

More than 11 million people in the United States take anticoagulation or antiplatelet medications, such as heparin or aspirin, to treat serious conditions like heart attack and stroke. However, these medications also put patients at risk of life-threatening bleeding in the case of injury or during surgery.

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Automated AKI Alert Prompts Change of Care, Shows No Impact on Patient Outcomes

HCPLive

Use of the electronic AKI alert system led to slight improvements in intervention rates and AKI diagnosis, although kidney function and patient-centered outcomes did not differ from patients receiving usual care.

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Afib Detected After Stroke: Link to Recurrent Events Questioned

Med Page Today

(MedPage Today) -- Cryptogenic stroke survivors who went on to get an insertable cardiac monitor (ICM) had a similar risk of recurrent stroke whether or not any atrial fibrillation (Afib, AF) ever turned up on monitoring, an observational study.

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Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 26 January 2024; doi:10.1038/s41569-023-00986-9 In this Review, Varga and colleagues provide an overview of the evidence on immune checkpoint inhibitor-induced heart failure and cardiac dysfunction that is unrelated to myocarditis, and discuss how pharmacological targeting of immune checkpoints might be a potential strategy to treat heart failure.

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Post-pandemic, US cardiovascular death rate continues upward trajectory

Medical Xpress - Cardiology

New research confirms what public health leaders have been fearing: The significant uptick in the cardiovascular disease (CVD) death rate that began in 2020 has continued. The continuing trend reverses improvements achieved in the decade before the COVID-19 pandemic to reduce mortalities from heart disease and stroke, the leading causes of death in the United States.

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Geovanni Faddoul, MD: IgAN Recurrence After Kidney Transplantation

HCPLive

Geovanni Faddoul, MD, discusses findings from his recent study examining the impact of induction and maintenance therapy on IgAN recurrence, graft survival, and mortality in kidney transplantation.

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Agepha Pharma and Caristo Diagnostics Team Up to Fight Coronary Inflammation

DAIC

Getty Images milla1cf Thu, 01/25/2024 - 20:44 January 25, 2024 — Agepha Pharma , a leading multinational pharmaceutical company with the first FDA-approved anti-inflammatory cardiovascular treatment ( LODOCO – colchicine, 0.5 mg tablets), together with Caristo Diagnostics , a leading cardiac disease diagnostics company with the novel CaRi-Heart technology to visualize and quantify coronary inflammation, announced today their collaboration to improve awareness and clinical education about the