Sat.Mar 23, 2024 - Fri.Mar 29, 2024

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Sotatercept's FDA Approval a New Chapter for Pulmonary Arterial Hypertension

Med Page Today

(MedPage Today) -- The FDA approved sotatercept (Winrevair) for treating pulmonary arterial hypertension (PAH) in adults, Merck announced on Tuesday. A novel activin signaling inhibitor, sotatercept is indicated to increase exercise capacity.

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Google Street View reveals how built environment correlates with risk of cardiovascular disease

Medical Xpress - Cardiology

Researchers have used Google Street View to study hundreds of elements of the built environment, including buildings, green spaces, pavements and roads, and how these elements relate to each other and influence coronary artery disease in people living in these neighborhoods.

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Alcohol raises heart disease risk, particularly among women

Science Daily - Heart Disease

Young to middle-aged women who reported drinking eight or more alcoholic beverages per week--more than one per day, on average--were significantly more likely to develop coronary heart disease compared with those who drank less, finds a study presented at the American College of Cardiology's Annual Scientific Session. The risk was highest among both men and women who reported heavy episodic drinking, or 'binge' drinking, and the link between alcohol and heart disease appears to be especially str

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Evidence that tirzepatide protects against diabetes-related cardiac damages

Cardiovascular Diabetology

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are effective antidiabetic drugs with potential cardiovascular benefits. Despite their well-established role in reducing the risk of major adverse cardiovas.

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Our Brains Are Getting Bigger, MRIs Show

Med Page Today

(MedPage Today) -- Human brains appeared to be getting bigger, temporal trends showed. From the 1930s to 1970s, brain volumes and cortical surface area of people who had neither dementia nor stroke became progressively larger, reported Charles.

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Young adults with migraine, other nontraditional risk factors may have higher stroke risk

American Heart News - Heart News

Research Highlights: Nontraditional risk factors for stroke were significantly associated with the development of strokes in adults younger than ages 35 to 45. Migraine was the most important nontraditional risk factor for stroke among both men and.

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Eggs may not be bad for your heart after all

Science Daily - Heart Disease

Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.

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Need 10,000 Daily Steps to Prevent Obesity? It May Depend on Genetics

Med Page Today

(MedPage Today) -- The daily step count needed to reduce the risk of obesity may be largely dependent on genetics, a retrospective cohort study indicated. Among U.S. adults without obesity in the All of Us Research Program, incidence of obesity.

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Social, environmental factors may raise risk of developing heart disease and stroke

American Heart News - Heart News

Research Highlights: People living in neighborhoods with more environmental adversities, including pollution, toxic sites, high traffic and few parks, had higher rates of cardiovascular disease and cardiovascular disease risk factors. This association.

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For younger women, mental health now may predict heart health later

Science Daily - Heart Disease

Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health conditions. A new study found that having anxiety or depression could accelerate the development of cardiovascular risk factors among young and middle-aged women.

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Wide Complex Tachycardia -- VT, SVT, or A Fib with RVR? If SVT, is it AVNRT or AVRT?

Dr. Smith's ECG Blog

A 69 y.o. male with pertinent past medical history including Atrial fibrillation, atrial flutter, cardiomyopathy, Pulmonary Embolism, and hypertension presented to the Emergency Department via ambulance for respiratory distress and tachycardia. Per EMS report, patient believes he has been in atrial fibrillation for 5 days, since coming down with flu-like illness with rhinorrhea, productive cough, SOB.

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SGLT2 Inhibitors Could Play a Role in Treating Gout

HCPLive

A new review considers how SGLT2 inhibitors like dapagliflozin and empagliflozin have been shown to clinically improve gout while reducing its cardiometabolic and renal comorbidities.

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More exposure to artificial, bright, outdoor nighttime light linked to higher stroke risk

American Heart News - Heart News

Research Highlights: A large study of residents in Ningbo, China, a major city of more than 8.2 million residents, found that exposure to more artificial, outdoor, nighttime light was associated with a higher risk of conditions that affect brain.

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Clear shift in arterial diseases in diabetes

Science Daily - Heart Disease

There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to new studies.

Diabetes 114
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Most Post-Stroke Depression Strikes Within 5 Years

Med Page Today

(MedPage Today) -- The vast majority of post-stroke depression (87.9%) occurred within the first 5 years after a stroke, suggesting a benefit for screening within that timeframe, according to a prospective study from the U.K. During an 18-year.

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A rare morphology of the cardiac fibroma in a child: a case report

Frontiers in Cardiovascular Medicine

Here we report a rare morphology of a cardiac fibroma in a child. A 2-year and 8-month-old toddler came for “chronic constipation” and was found to have a heart murmur on cardiac auscultation. Further transthoracic echocardiography suggested “a strong echogenic mass in the left ventricular wall, with some part of “a string of beads” in shape extending into left ventricle outflow tract”, which was atypical for either a tumor, thrombus or vegetation.

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Feds to probe UPMC heart implant practices

Becker's Hospital Review - Cardiology

The House Committee on Energy and Commerce is asking the FDA to investigate whether patients received experimental heart implants at UPMC Children’s Hospital of Pittsburgh without consent or proper information, the Pittsburgh Post-Gazette reported March 24.

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Study finds high prevalence of hidden brain changes in people with heart disease

Science Daily - Heart Disease

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

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ADHD stimulants may increase risk of heart damage in young adults

Medical Xpress - Cardiology

Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed stimulants, according to a study presented at the American College of Cardiology's Annual Scientific Session.

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Novel CAR-T Cell Therapy Trial for Lupus Launched by Atlantic Health System

HCPLive

Mohamed Cherry, MD, and Neil Kramer, MD, shed light on a phase 1 trial using CAR-T cell therapy for SLE and its potential implications for lupus treatment.

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Medtronic Announces FDA Approval of Newest-generation Evolut TAVR System for Treatment of Symptomatic Severe Aortic Stenosis

DAIC

milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis. The latest Evolut FX+ TAVR system maintains the valve performance benefits of the legacy Evolut TAVR platform and is designed to facilitate coronary access.

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Virtual rehabilitation provides benefits for stroke recovery

Science Daily - Stroke

A stroke often impacts a person's ability to move their lower body from the hips down to the feet. This leads to diminished quality of life and mental health in addition to increased susceptibility to falls. But now, researchers are exploring new treatment methods to help bridge the service delivery gap, and recovery outcomes, for patients after a stroke.

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Young adults with migraine, other nontraditional risk factors may have higher stroke risk

Science Daily - Heart Disease

Nontraditional risk factors such as migraines are as important as traditional risk factors like high blood pressure for adults younger than ages 35-45, finds new study.

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FDA Warns About Impella Left-Sided Blood Pumps, Linked to 49 Deaths

HCPLive

FDA issued a warning for the the Impella left-sided blood pumps as it had received many reports of heart-wall tears, increasing the risk of death, hypertension, and more.

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Living Past 100: Insights from Centenarians on a Long, Healthy Life

Dr. Paddy Barrett

Living to more than 100 years of age is a rare feat. Surviving this long with a good quality of life is even rarer. What can healthy centenarians teach us about achieving such a lofty goal? And what can we reasonably expect for ourselves? Let’s start with some simple facts. While the average lifespan has increased dramatically over the last 1,000 years, the maximum human lifespan has changed very little.

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Study discovers how a magnesium cellular transport 'pump' plays a vital role in cardiac function

Medical Xpress - Cardiology

Magnesium is a mineral critical to a wide range of biological functions, and a new study takes aim at how it's transported to address cardiac dysfunction and other diseases, opening new possibilities for treatment.

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Risk analysis of the association between different hemoglobin glycation index and poor prognosis in critical patients with coronary heart disease-A study based on the MIMIC-IV database

Cardiovascular Diabetology

The hemoglobin glycation index (HGI) is the difference between the observed and predicted values of glycosylated hemoglobin (HbA1c), which is closely associated with a variety of poor prognoses. However, there.

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Elixir Medical Receives FDA Breakthrough Device Designation for DynamX BTK System for Below-The-Knee Arterial Disease

DAIC

Elixir Medical has announced it has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA) for its DynamX BTK System, a novel, adaptive implant for use in the treatment of narrowed or blocked vessels below-the-knee (BTK) in patients with chronic limb-threatening ischemia (CLTI). The company reports this broadens the use of the novel bioadaptor platform technology beyond the treatment of coronary artery disease.

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Lupus Patients with Nephritis at Greater Risk of Cholesterol Disorders, Cardiovascular Events

HCPLive

Presence of nephritis in SLE patients is linked to higher cardiovascular risk factors and 3-fold increase in incidence of cardiovascular mortality.

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Study finds link between getting too little sleep and high blood pressure

Medical Xpress - Cardiology

Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a study presented at the American College of Cardiology's Annual Scientific Session.

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ADHD stimulants may increase risk of heart damage in young adults, study finds

Science Daily - Heart Disease

Young adults who were prescribed stimulant medications for attention-deficit/hyperactivity disorder (ADHD) were significantly more likely to develop cardiomyopathy (weakened heart muscle) compared with those who were not prescribed stimulants, in a new study.

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Abbott Announces First Procedures in ENVISION Trial of Navitor TAVI System to Treat Patients With Severe Aortic Stenosis

DAIC

milla1cf Mon, 03/25/2024 - 07:00 March 25, 2024 — Abbott announced the first patient has been enrolled in the ENVISION investigational device exemption (IDE) clinical trial. The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve).

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Contemporary pharmacological treatment and management of heart failure

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 26 March 2024; doi:10.1038/s41569-024-00997-0 In this Review, Bozkurt provides an overview of the management of patients with heart failure across the full range of left ventricular ejection fraction, derived from the recommendations in the latest US and European guidelines.

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Deepak Sambhara, MD: Impact of Aflibercept 8 mg Durability for AMD, DME

HCPLive

Deepak Sambhara, MD, discusses how clinical practice has responded to the introduction of aflibercept 8 mg and the significance of extended treatment intervals for patients with retinal diseases.

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Getting too little sleep linked to high blood pressure

Science Daily - Heart Disease

Sleeping fewer than seven hours is associated with a higher risk of developing high blood pressure over time, according to a new study.

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CLS Health Cardiologists Achieve Historic First with Transcarotid TAVR in Southeast Houston

DAIC

milla1cf Mon, 03/25/2024 - 07:30 March 25, 2024 — In a groundbreaking medical advancement, three esteemed cardiologists from CLS Health , Dr. Bahaeddin Shabaneh , Dr. Fethi Benraouane , and Dr. Molham Aldeiri , have successfully performed the first series of transcarotid Transcatheter Aortic Valve Replacement (TAVR) procedures ever done in Southeast Houston.

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Study finds high prevalence of hidden brain changes in people with heart disease

Medical Xpress - Cardiology

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.