Sat.Mar 02, 2024 - Fri.Mar 08, 2024

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Wegovy Approved for Heart Disease Prevention

Med Page Today

(MedPage Today) -- The FDA approved semaglutide (Wegovy) to reduce the risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and either obesity or overweight, the agency announced on Friday. A GLP-1 receptor.

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Boehringer Ingelheim Announces $35 Monthly Price Cap on Inhalers for Asthma, COPD Patients

HCPLive

On March 07, 2024, Boehringer Ingelheim announced it would be instituting a $35 per month out-of-pocket cost cap for its portfolio of inhaler products, with this cap going into effect on June 01, 2024.

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Sweetened drinks linked to atrial fibrillation risk

American Heart News - Heart News

Research Highlights: An analysis of health data in the UK Biobank found a 20% higher risk of irregular heart rhythm, known as atrial fibrillation, among people who said they drank two liters or more per week (about 67 ounces) of artificially sweetened.

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Case report of belt electrode-skeletal muscle electrical stimulation for acute heart failure with severe obesity: a novel therapeutic option for acute phase rehabilitation

Frontiers in Cardiovascular Medicine

Background Belt electrode skeletal muscle electrical stimulation (B-SES) is an emerging therapy anticipated to yield more favorable outcomes than conventional neuromuscular electrical stimulation (NMES), owing to its larger stimulation area. However, information on its efficacy and safety in patients with heart failure remains limited. Case presentation A 43-year-old man with a body mass index of 41 kg/m 2 was admitted to our hospital for acute heart failure due to dilated cardiomyopathy.

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CVD Risks Tied to Teeny-Tiny Plastics Lodged in Atherosclerotic Plaque

Med Page Today

(MedPage Today) -- It was common for tiny plastic particles from the environment to infiltrate people's vascular lesions, foreshadowing future cardiovascular disease in patients who underwent carotid endarterectomy, an observational study showed.

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Semaglutide (Wegovy) Receives FDA Label Expansion to Include Cardiovascular Risk Reduction

HCPLive

On March 08, 2024, the FDA approved semaglutide 2.4 mg (Wegovy) to reduce cardiovascular risk in adults with obesity or overweight and heart disease based on the SELECT trial.

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Microplastics, Nanoplastics, and Major Cardiac Events

CardiacWire

A landmark NEJM study revealed that many patients with carotid artery disease might have microplastics and nanoplastics (MNPs) embedded in their carotid plaque, and those patients have a massive 4.5-fold greater risk of heart attack, stroke, or death within three years. The researchers examined carotid plaque specimens from 257 patients with asymptomatic carotid artery disease, analyzing their plaque for the presence of 11 MNPs, and tracking the patients’ cardiovascular outcomes over 34 months.

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FDA Says Eating Yogurt May Reduce Diabetes Risk

Med Page Today

(MedPage Today) -- The FDA said that it will not object to the use of a qualified health claim that eating yogurt is associated with a reduced risk of type 2 diabetes, the agency announced Friday. After a review of the evidence -- albeit limited.

Diabetes 132
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Tapinarof Cream for Atopic Dermatitis: An Interim Analysis of Results in Adults, Children

HCPLive

A new analysis of the phase 3 ADORING 3 extension trial involved a large, diverse population and the analysis showed that 91% of eligible participants from previous phases rolled over into this trial.

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More than half of American Indian youth may have abnormal or high cholesterol

Science Daily - Heart Disease

More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovascular disease, a new study suggests. In some cases, these levels -- specifically high low-density lipoprotein (LDL) cholesterol, often thought of as 'bad cholesterol,' -- were linked to plaque buildup and cardiovascular events, such as heart attack and stroke.

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Advanced detection of coronary artery disease via deep learning analysis of plasma cytokine data

Frontiers in Cardiovascular Medicine

The 2017 World Health Organization Fact Sheet highlights that coronary artery disease is the leading cause of death globally, responsible for approximately 30% of all deaths. In this context, machine learning (ML) technology is crucial in identifying coronary artery disease, thereby saving lives. ML algorithms can potentially analyze complex patterns and correlations within medical data, enabling early detection and accurate diagnosis of CAD.

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Afib Might Be a Not-So-Pleasant Aftertaste of Sweetened Beverages

Med Page Today

(MedPage Today) -- Overconsumption of beverages with added sugar or artificial sweetener, already associated with several cardiometabolic diseases, showed new links to atrial fibrillation (Afib or AF) in a prospective cohort study. Within the.

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Psychological Interventions Effectively Decrease Depression, Anxiety in Patients with Fibromyalgia

HCPLive

The overall effect of psychological interventions on patients with fibromyalgia was -0.31 for depressive symptoms and -0.15 for anxiety symptoms, which were deemed statistically significant.

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Children with 'lazy eye' are at increased risk of serious disease in adulthood

Science Daily - Heart Disease

Adults who had amblyopia ('lazy eye') in childhood are more likely to experience hypertension, obesity, and metabolic syndrome in adulthood, as well as an increased risk of heart attack, finds a new study.

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Clinical significance of regional constructive and wasted work in patients receiving cardiac resynchronization therapy

Frontiers in Cardiovascular Medicine

Background Previous studies have shown that global constructive work (CW) and wasted work (WW) predict response to cardiac resynchronization therapy (CRT). This study evaluated the predictive value of regional CW and WW for reverse remodeling and clinical outcomes after CRT. Methods We performed a prospective study involving 134 CRT candidates with left bundle branch block and left ventricular ejection fraction ≤35%.

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FDA Clears First OTC Continuous Glucose Monitor

Med Page Today

(MedPage Today) -- The first over-the-counter continuous glucose monitor (CGM) was cleared for use by adults with or without diabetes, the FDA announced on Tuesday. The Dexcom Stelo Glucose Biosensor System is an integrated CGM (iCGM) that will.

Diabetes 109
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FDA Clears Dexcom Stelo Sensor, First OTC Glucose Sensor in Agency History

HCPLive

The FDA has greenlit Dexcom's Stelo Glucose Biosensor System, marking a historic first as the first continuous glucose monitors to be available over-the-counter.

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Coronary artery calcium score predictive of heart attacks, strokes

Science Daily - Heart Disease

Coronary artery calcium scoring with CT can identify symptomatic patients with a very low risk of heart attacks or strokes. Researchers said the findings may one day help some patients with stable chest pain avoid invasive coronary angiography.

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Young man with Gunshot wound to right chest with hemorrhagic shock, but bullet path not near heart

Dr. Smith's ECG Blog

A young man presented with a gunshot wound to the right chest, with hemo-pneumothorax and hemorrhagic shock. He got a chest tube and intubation and massive transfusion and stabilized. CT of chest showed the bullet path through his right lung but nowhere near his heart. But he did get an EKG: What is this? There were times when it would be usurped by sinus tachycardia, then return to this rhythm.

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10,000 Steps Lowers Death Risk; Obesity Drug Beats Wegovy; Lead in Cinnamon Warning

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Accruing about 10,000 steps per day was associated with the lowest mortality risk independent of sedentary time, but any amount above 2,200 steps a day showed mortality.

Obesity 108
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Effects of continuous supplementation of Acanthopanax senticosus Harms on the cardiac autonomic function of community-dwelling elderly individuals during resting and standing tests: a randomized controlled trial

Frontiers in Cardiovascular Medicine

Background Cardiac autonomic function (CAF) decreases with aging, and Acanthopanax senticosus Harms (ASH) consumption reportedly induces anti-stress effects. This study aimed to assess the effect of continuous supplementation of ASH on CAF during resting and standing tests in the elderly population. Methods This double-blind, randomized controlled trial was conducted in the morning in a laboratory setting and was carried out between June 2017 and July 2017 at Kambaikan, Doshisha University (Kara

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New Findings Compare Safety of Risankizumab Versus Apremilast Among Psoriasis Patients

HCPLive

In phase 4 data from the IMMpulse study, presented at AAD 2024, comparisons in efficacy were highlighted between risankizumab and apremilast for psoriasis patients eligible for systemic therapy.

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World's longest-living heart transplant recipient named

Becker's Hospital Review - Cardiology

"Discover the incredible story of Bert Janssen, the Dutch man who has lived with a donor heart for 39 years and 252 days, officially confirmed as the world's lo

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Use of CGM Linked to Lower Risk of Retinopathy in Type 1 Diabetes

Med Page Today

(MedPage Today) -- In patients with type 1 diabetes, use of continuous glucose monitoring (CGM) devices -- alone or with insulin pumps -- was associated with lower odds of developing diabetic retinopathy and proliferative diabetic retinopathy.

Diabetes 107
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When the conventional algorithm diagnoses the ECG as COMPLETELY NORMAL, but there is in fact OMI, what does the Queen of Hearts PM Cardio AI app say? (with 10 case examples)

Dr. Smith's ECG Blog

I have often written about how an ECG interpreted as "normal" by a conventional algorithm may well be manifesting OMI, or even long QT or hyperkalemia. I have collected 51 OMI cases that were diagnosed as completely normal by the conventional automated computer algorithm. Shifa Karim and Gabe Keller helped with a project to assess all these ECGs with the Queen of Hearts.

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FDA Rejects sNDA of Tasimelteon for Treating Insomnia

HCPLive

FDA issued a Complete Response Letter to Vanda Pharmaceuticals stating tasimelteon for treating insomnia cannot be approved in its current form due to identified deficiencies.

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Teen Topics – The Top 10 Things to Remember About CHD as an Adult

Conquering CHD

It often seems that the “taboo topics” in life aren’t really all that relevant until your teen years. As the seasons change, new milestones come and go. This can be an especially trying time in the life of an adolescent with congenital heart disease, especially as they are undergoing the major transition of leaving the nest and going off to college, joining the workforce, or just moving far from home.

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Cardiometabolic Disorders Tend to Accompany a 'Lazy Eye'

Med Page Today

(MedPage Today) -- Somehow, people with persistent amblyopia (also known as "lazy eye") from childhood had a higher risk of cardiometabolic disorders in adulthood, an observational cohort study showed. Within the U.K. Biobank, people over 40 years.

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Instructors' Collection ECG: Regular Really Wide QRS Tachycardia

ECG Guru

The Patient: Unfortunately, this is an old tracing, and we do not have patient information, other than the list of medications the patient has been taking, (Lasix, Capoten, Ntg, and Procardia). Lasix (furosemide) is a potassium – wasting diuretic. Capoten (captopril) is an ACE inhibitor. Ntg is presumably sublingual nitroglycerine used for angina.

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Sleep Experts Discuss Dangers of Daylight Savings Time Transition

HCPLive

In time for daylight saving time starting on March 10, sleep experts weigh in on the harms of the daylight saving transition, such as increased risks for cardiovascular events, car accidents, and mortality.

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A Look at February's Top 10

DAIC

February was a short but busy month in the diagnostic and interventional cardiology world, with a lot of news being generated and clinical trial data released. Here is a look at last month's Top 10. 1. Ismail El-Hamamsy, MD, PhD, Named President of the Heart Valve Society 2. ISC 2024 Late-breaking Science Finding from ZODIAC Study: Position of Head Before Surgery May Improve Stroke Patient’s Neurological Function 3.

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One-Week GLP-1 Agonist Hold Not Enough Before Anesthesia?

Med Page Today

(MedPage Today) -- Use of GLP-1 receptor agonists was linked with increased residual gastric content on preprocedural gastric ultrasonography, even after fasting for the guideline-recommended duration, a cross-sectional study showed. In 124 patients.

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High cholesterol was twice as prevalent among American Indian teens and young adults

American Heart News - Heart News

Research Highlights: A study of more than 1,400 people in U.S. tribal communities found that high cholesterol was twice as prevalent among American Indian adolescents and young adults compared to the overall U.S. population. The study also noted that.

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Poor Sleep Habits Tied to Diabetes Risk, Even with Healthy Dietary Habits

HCPLive

Results of a new analysis underscore the significance of sleep health in mitigating type 2 diabetes risk, revealing that even an optimal diet may not fully offset the negative impact of inadequate sleep.

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Revascularization Strategies in Stable Coronary Artery Disease: ISCHEMIA Trial Insights

Cardiology Update

In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronary artery disease. The study evaluated outcomes associated with an invasive strategy involving angiography and percutaneous coronary intervention (PCI) or surgical coronary artery bypass grafting (CABG), compared to a conservative strategy involving initial medical therapy.

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Semaglutide Reduced Inflammatory Biomarkers in HIV Patients With Lipohypertrophy

Med Page Today

(MedPage Today) -- DENVER -- People with HIV who received semaglutide (Ozempic, Wegovy) had reduced levels of several inflammatory biomarkers associated with cardiovascular disease, a randomized controlled trial showed. After 32 weeks, interleukin.

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Cardiac College for (Freshly Diagnosed) Women: “Your heart is like a house”

Heart Sisters

The more heart patients learn about heart disease, the better we can manage the 8,765 hours per year we aren't spending with our cardiologist. Here's how 'Cardiac College for Women' can help us manage those hours.