Sat.Sep 21, 2024 - Fri.Sep 27, 2024

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ESC 2024 Highlights

Cardiology Update

Dr. Chadi Alraies discusses some of the important trials presented at the European Society of Cardiology 2024 congress. Read more about the important ESC 2024 highlights. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram. The post ESC 2024 Highlights appeared first on Cardiology Update.

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Sexual and Gender Minorities More Likely to Have Adverse Brain Outcomes

Med Page Today

(MedPage Today) -- People who identified as a sexual or gender minority (LGBTQ+) had a higher likelihood of adverse brain health outcomes, cross-sectional data showed. Among nearly 400,000 participants in the All of Us research program, sexual.

Outcomes 130
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ECG Blog #448 — A Young Man with Chest Pain.

Ken Grauer, MD

The ECG in Figure-1 was obtained from a previously healthy man in his early 20s — who initially presented with GI symptoms, that then evolved into CP ( C hest P ain ). The patient was thought to have anxiety. QUESTIONS: Given the above history — How would YOU interpret the initial ECG that is shown in Figure-1 ? Does the patient's age infuence your interpretation?

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Soil and water pollution and cardiovascular disease

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 September 2024; doi:10.1038/s41569-024-01068-0 In this Review, Münzel and colleagues describe the adverse effects of soil and water pollution, including heavy metal, pesticide, and microplastic and nanoplastic pollution, on cardiovascular health and provide an overview of the eco-disruptive causes of this pollution.

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Measure of body roundness may help to predict risk of cardiovascular disease

Medical Xpress - Cardiology

Having a high body roundness index (BRI) over a 6-year period was associated with an increased risk of developing cardiovascular disease for adults older than age 45, according to new research published today in the Journal of the American Heart Association. Previous research has indicated that BRI, a measure to reflect abdominal fat and body shape, may be helpful to predict CVD risk.

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The heart of the question: Who can get Medicare-covered weight loss medicine?

Science Daily - Heart Disease

With Medicare now covering semaglutide for people with obesity and cardiovascular disease who don't have diabetes, a study looks at who that might include, depending on what cutoffs prescription plans apply.

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Estimated Long-Term Benefits of Finerenone in Heart Failure

JAMA Cardiology

This prespecified analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial investigates the long-term effects of treatment with the nonsteroidal mineralocorticoid receptor antagonist, finerenone, in patients with heart failure with mildly reduced or preserved ejection fraction.

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Women still missing out on treatment for cardiovascular disease, despite major progress in disease management

Medical Xpress - Cardiology

Women in the UK, and elsewhere, are still missing out on vital treatment for their No 1 killer—cardiovascular disease—despite significant progress in the medical management of heart disease and stroke, concludes a consensus statement published online in the journal Heart.

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Edgewise Therapeutics’ EDG-7500 Emerges as New HCM Contender

CardiacWire

A new HCM competitor emerged last week, after Edgewise Therapeutics’ EDG-7500 showed strong evidence of its safety and efficacy in a pair of early-stage trials. EDG-7500 is an oral cardiac sarcomere modulator designed to slow early contraction velocity and address impaired cardiac relaxation associated with HCM and other diastolic dysfunctions. EDG-7500 is later to the HCM party than BMS’ Camzyos and Cytokinetics’ aficamten, but is differentiated by its potential to improve blood flow without sa

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Acute artery occlusion -- which one?

Dr. Smith's ECG Blog

Written by Willy Frick with edits by Ken Grauer A woman in her 70s with a history of hypertension presented with acute onset shortness of breath. She was out walking her dog when she developed sudden dizziness and light-headedness. When EMS found her, she was dyspneic and diaphoretic. Her ECG is shown below: What do you think? The conventional machine algorithm interpreted this ECG as STEMI.

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DAA Marketing Payments From Manufacturers Linked to Physician Prescribing Patterns

HCPLive

Physicians who received pharmaceutical industry payments related to 4 different direct-acting antivirals were more likely to prescribe these medications.

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Soil and water pollution: An invisible threat to cardiovascular health

Medical Xpress - Cardiology

Pesticides, heavy metals, micro- and nanoplastics in the soil and environmentally harmful chemicals can have a detrimental effect on the cardiovascular system, according to a review paper published today in Nature Reviews Cardiology.

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Evidence of a bi-directional relationship between heart failure and diabetes: a strategy for the detection of glucose abnormalities and diabetes prevention in patients with heart failure

Cardiovascular Diabetology

Prevalence of heart failure (HF) and diabetes are markedly increasing globally. In a population of HF patients, approximately 40% have diabetes which is associated with a more severe HF, poorer cardiovascular.

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The Computer and Overreading Cardiologist call this completely normal. Is it?

Dr. Smith's ECG Blog

This is another case sent by the undergraduate (who is applying to med school) who works as an EKG tech. The undergraduate is now willing to identify himself: Hans Helseth. A 56 year old male with a history of diabetes, dyslipidemia, hypertension, and coronary artery disease presented to the emergency department with sudden onset weakness, fatigue, lethargy, and confusion.

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Heplisav-B Vaccine Bests Standard 3-Dose Series in Heart, Lung Transplant Candidates

HCPLive

Heplisav-B provided a greater vaccine completion rate and higher HBV seroprotection than the conventional 3-dose Recombivax HB in thoracic organ transplant candidates.

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Human and other primate hearts differ genetically, says study

Medical Xpress - Cardiology

A team at the Hübner and Diecke Labs at the Max Delbrück Center has shown how human and non-human primate hearts differ genetically. The study, published in Nature Cardiovascular Research, reveals evolutionary adaptations in human hearts and provides new insights into cardiac disease.

Research 105
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Babies born after fertility treatment have higher risk of heart defects, study suggests

Science Daily - Heart Disease

The risk of being born with a major heart defect is 36% higher in babies who were conceived after assisted reproductive technology, such as in vitro fertilization (IVF), according to results of a very large study.

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Tissue inhibitor of metalloproteinase (TIMP)-1 predicts failure of recovery of ejection fraction in acute heart failure with reduced ejection fraction

Open Heart

Background Heart failure (HF) with improved ejection fraction (HFimpEF) is a recently identified phenotype of HF, which had better cardiovascular outcomes compared with persistent HF with reduced ejection fraction (HFrEF). The present study aimed to investigate the predictive value of tissue inhibitor of metalloproteinase (TIMP)-1 and matrix metalloproteinases-9 (MMP-9) in the recovery of left ventricular ejection fraction (LVEF).

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Treating iron deficiency in patients with heart failure: what, why, when, how, where and who

Heart BMJ

For patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, iron deficiency is common and associated with more severe symptoms, worse quality of life and an increased risk of hospitalisations and death. Iron deficiency can be swiftly, effectively and safely treated by administering intravenous iron, either as ferric carboxymaltose or ferric derisomaltose, which improves patient well-being and reduces the risk of hospitalisations including those for heart fai

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Absolute, Functional Iron Deficiency Affects Large Proportion of US Adults

HCPLive

Rates of absolute and functional iron deficiency were high among adults in the US, even in those without anemia, heart failure, or chronic kidney disease.

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Tragus Stimulation for High BP; House Passes HEARTS Act; Risk in Pregnancy Surrogacy

Med Page Today

(MedPage Today) -- Noninvasive, low‐level tragus stimulation modestly reduced blood pressure (BP) in relatively healthy people with grade 1 hypertension. (Journal of the American Heart Association) The House passed the HEARTS Act, which.

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Peripheral artery disease: Leg pain, leg cramps, lingering foot wounds among symptoms

Medical Xpress - Cardiology

Leg pain and leg cramps aren't always an orthopedic issue: Both can be signs of peripheral artery disease, or PAD, a serious blood-flow issue with implications for the heart. In this expert alert, Young Erben, M.D., a vascular surgeon at Mayo Clinic in Jacksonville, Florida, explains how the most common form, PAD that affects the legs and feet, is treated.

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Universal definition of myocardial infarction: what must we know? What is next?

Heart BMJ

In the beginning of the 20th century, the first reports of the clinical manifestations of myocardial infarction (MI) appeared, followed around a decade later by reports regarding the electrocardiographic (ECG) changes associated with MI ( figure 1 ). From the middle of the 20th century, the application of assays for muscle enzymes for the diagnosis of MI became widespread, culminating in the WHO definition of MI based on clinical, ECG and cardiac enzyme criteria.

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FDA Accepts sNDA for Roflumilast Foam as Scalp, Body Psoriasis Treatment

HCPLive

The FDA has set a PDUFA target action date of May 22, 2025, for roflumilast foam 0.3% for individuals aged ≥12 with scalp and body psoriasis.

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Timely Skin Cancer Screening After Organ Transplant Still Lacking

Med Page Today

(MedPage Today) -- Recent skin cancer risk stratification guidelines did not improve rates of timely dermatologic follow-up visits among solid organ transplant recipients, according to an analysis of claims data. The rate of post-transplant dermatology.

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Is Ultra-Processed Food Really That Bad For You?

Dr. Paddy Barrett

Ultra-processed foods are a modern invention. They are here to stay. But are ultra-processed foods really that bad for you? The answer is yes. Kind of. Let Me Explain. There is a huge body of evidence that points to the harms of ultra-processed foods on health outcomes. For every serving of ultra-processed food, the risk of an early death increases by 18% 1.

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The burden of atrial fibrillation in the Asia–Pacific region

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 25 September 2024; doi:10.1038/s41569-024-01091-1 The burden of atrial fibrillation (AF) is increasing worldwide; however, most existing data on AF epidemiology are from Western regions. According to our analyses, the estimated absolute prevalence of AF in the Asia–Pacific region in 2023 was approximately 80 million, which is much higher than has been calculated for other global regions.

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Precocious Puberty More Common in Children with Hidradenitis Suppurativa

HCPLive

A new case-control study reported a higher prevalence of precocious puberty in children and adolescents with HS compared with controls.

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New approach to defibrillation may improve cardiac arrest outcomes

Science Daily - Heart Disease

A new observational study suggests the position in which responders initially place the two defibrillator pads on the body may make a significant difference in returning spontaneous blood circulation after shock from a defibrillator.

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GLP-1 Agent May Hold Opioid Use Disorder Benefit

Med Page Today

(MedPage Today) -- Semaglutide (Ozempic, Wegovy) may help reduce the risk of an opioid overdose in certain people, an emulation target trial suggested. Over a 1-year follow-up, people with comorbid type 2 diabetes and opioid use disorder (OUD.

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NONSUSTAINED VT

ECG Guru

Extract from a Holter ECG, 2 continuous strips, recorded at 25 mm/s. At the top you can see a broad complex tachycardia without recognizable P waves, which ends spontaneously after 2 beats in the lower section. This is a VT. The very first beat in the 1st strip is most probably a fusion beat. After the end of the VT in the 2nd strip, a narrow QRS complex appears, here you can also recognize that atrial fibrillation is present.

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Biosimilars Saved $12.3 Billion in 2023, a Fraction of Potential Savings

HCPLive

To date, biosimilars have supported 495 million incremental days of therapy that patients would otherwise not have received.

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Measure of body roundness may help to predict risk of cardiovascular disease

American Heart News - Heart News

Research Highlights: Body roundness index — a measure to reflect abdominal body fat and height that some health care professionals believe better reflects the proportion of body fat and visceral fat than body mass index — may help to predict a.

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Obstructive sleep apnea may increase risk of abdominal aortic aneurysms

Medical Xpress - Cardiology

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health. "Chronic Intermittent Hypoxia Facilitates the Development of Angiotensin II-Induced Abdominal Aortic Aneurysm in Male Mice" was recently published in the Journal of Applied Physiology.

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How to Tell When Imaging Equipment Has Reached End-of-Life (and How to Extend Its Value)

Cassling

Like humans, medical imaging equipment shows signs of aging. But instead of creaky joints, wrinkles, or gray hair, the machinery gives other hints that it is wearing out and that it might be time for you to make a change. Here are five signs that your imaging equipment is approaching its last lap, plus tips on what you can do to get a little more usage out of it before it completely gives out.

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Study Reveals Factors Associated with Non-DKD on Kidney Biopsy in Patients with Diabetes

HCPLive

Lack of retinopathy, lower hemoglobin A1c levels, preserved eGFR, microalbuminuria, and lower UPCR were linked to non-DKD.

Diabetes 105
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ATRIAL FIBRILLATION

ECG Guru

Unfortunately, I can't remember who the author of this ECG is. Perhaps he/she will get in touch with me. However, the ECG is very nice (despite the less than optimal recording quality) and that's why I want to post it. I don't know the history. In the first section of the ECG we see coarse fibrillation waves and QRS complexes with very different RR intervals, which is why this is atrial fibrillation.