Sun.Jun 23, 2024

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Diabetes Dialogue: INHALE-3 and Diabetes Tech Updates, with Grazia Aleppo, MD

HCPLive

In this episode, hosts are joined by Grazia Aleppo, MD, for a discussion on the use of inhaled insulin following the INHALE-3 trial and relevant updates in diabetes technology at ADA 2024.

Diabetes 124
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VF arrest at home, no memory of chest pain. Angiography non-diagnostic. Does this patient need an ICD? You need all the ECGs to know for sure.

Dr. Smith's ECG Blog

Written by Willy Frick A man in his 50s was at home with his family when they heard a thud and rushed into the room to find him unconscious with agonal respirations. His daughter immediately started CPR and another family member called EMS. When EMS arrived the patient was in ventricular fibrillation. They shocked him twice before return of spontaneous circulation.

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What to Know About Cannabis Use and Diabetes, with Halis Akturk, MD

HCPLive

Halis Akturk, MD, offers an overview of the growing prevalence and dangers associated with cannabis use among patients with type 1 diabetes.

Diabetes 110
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“What? So what? Now what?” Self-reflection for the new heart patient

Heart Sisters

Most patients aren't experienced enough to be competent in handling a scary new diagnosis, but here's how self-reflection can make a difference during recovery.

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Diabetes Dialogue: ADA Introduces Obesity Association, with Robert Gabbay, MD, PhD

HCPLive

In the special on-site ADA 2024 episode, hosts are joined by the ADA's Chief Scientific and Medical Officer Robert Gabbay, MD, PhD, to discuss the newly formed Obesity Association.

Obesity 83
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Novel Triple-Hormone Agonist Boosts Beta-Cell Function in T2D

Med Page Today

(MedPage Today) -- ORLANDO -- An investigational triple-hormone receptor agonist improved metabolic profiles of people with obesity with or without type 2 diabetes, an exploratory biomarker analysis of a phase II trial found. After 36 weeks.

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Semaglutide leads to greater weight loss in women than men with HF and improves HF symptoms

Science Daily - Heart Disease

Semaglutide, a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options. Women experienced greater weight loss and the same symptom benefits compared with men.

Obesity 73

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MOMENTUM: Pemvidutide Boasts "Class-Leading" Lean Mass Preservation with Weight Loss

HCPLive

MOMENTUM trial data shows pemvidutide reduced body weight by 15.6%, with 78.1% fat loss, highlighting the GLP-1/Glucagon receptor agonist's ability to achieve significant weight reduction and minimal muscle loss.

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Automated Insulin Pump Helps Type 2 Diabetes Control

Med Page Today

(MedPage Today) -- ORLANDO -- Putting type 2 diabetes patients on an automated insulin delivery (AID) pump improved glycemic control, the SECURE-T2D pivotal trial showed. Type 2 diabetes patients started on the Omnipod 5 System, currently approved.

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Role of arachidonic acid in ischemic heart disease under different comorbidities: risk or protection?

Cardiovascular Diabetology

In a translational study involving animal models and human subjects, Lv et al. demonstrate that arachidonic acid (AA) exhibits cardioprotective effects in diabetic myocardial ischemia, suggesting a departure f.

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Resection of the entire first rib for giant osteochondroma by trans manubrial approach: a case report and review of the literature

Journal of Cardiothoracic Surgery

First rib tumors are extremely rare. Its compression of neurovascularity can easily lead to severe complications such as thoracic outlet syndrome, so early surgical resection is crucial. However, there is no s.

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RNAseq of INOCA patients identifies innate, invariant, and acquired immune changes: potential autoimmune microvascular dysfunction

Frontiers in Cardiovascular Medicine

BackgroundIschemia with non-obstructive coronary arteries (INOCA) is a major clinical entity that involves potentially 20%–30% of patients with chest pain. INOCA is typically attributed either to coronary microvascular disease and/or vasospasm, but is likely distinct from classical coronary artery disease (CAD).ObjectivesTo gain insights into the etiology of INOCA and CAD, RNA sequencing of whole blood from patients undergoing both stress testing and elective invasive coronary angiography (ICA)

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A case of lung metastasis from gastric cancer presenting as ground-glass opacity dominant nodules

Journal of Cardiothoracic Surgery

Most metastatic lung tumors present as solid nodules on chest computed tomography (CT). In contrast, ground-glass opacity on chest computed tomography usually suggests low-grade malignant lesions such as adeno.

Cancer 52
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Study Links Newer GLP-1 Receptor Agonists to Population-Level Improvements in HbA1c

HCPLive

An analysis of over 2.5 million patients with type 2 diabetes shows newer GLP-1 RAs are linked to lower HbA1c levels.

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Prognostic role of CRABP2 in lung cancer: a meta-analysis

Journal of Cardiothoracic Surgery

The prognostic value of cellular retinoic acid-binding protein 2 (CRABP2), in lung cancer patients remains to be uncertained. Therefore, our research attempted to assess the relationship between CRABP2 and sur.

Cancer 52
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LX9211 Reduces Diabetic Nerve Pain, Improves Quality of Life in Phase 2 Trial

HCPLive

Use of LX9211 showed significant benefits for diabetic peripheral neuropathic pain in the phase 2 RELIEF-DPN 1 trial.

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Investigation of mediastinal lymph node dissection in clinical stage IA pure-solid non-small cell lung cancer patients

Journal of Cardiothoracic Surgery

To explore the independent predictors of pathological mediastinal lymph node (pN2) metastasis in clinical stage IA (cIA) pure-solid non-small cell lung cancer (NSCLC) patients, and to find an appropriate metho.

Cancer 52
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Understanding Eosinophilic Meningitis: A Comprehensive Overview

BMH Medical Journal

Eosinophilic meningitis (EM) presents a diagnostic challenge due to its varied etiologies, encompassing both infectious and non-infectious causes. Typically, cerebrospinal fluid (CSF) devoid of eosinophils serves as the norm, with their presence indicating a potential underlying condition such as parasitic infections or other systemic disorders.

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Assessment of subclinical LV myocardial dysfunction in T2DM patients with diabetic peripheral neuropathy: a cardiovascular magnetic resonance study

Cardiovascular Diabetology

Diabetic peripheral neuropathy (DPN) is the most prevalent complication of diabetes, and has been demonstrated to be independently associated with cardiovascular events and mortality. This aim of this study wa.

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Time to Benefit and Harm of Direct Oral Anticoagulants in Device-Detected Atrial Fibrillation: A Pooled Analysis of the NOAH-AFNET 6 and ARTESiA Trials

HeartRhythm

Direct oral anticoagulants (DOACs) reduce stroke risk in patients with device-detected atrial fibrillation (DD-AFib) but increase major bleeding risk. The time to benefit (TTB) and time to harm (TTH) are not well quantified.

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The Association of Mitral Annular Calcification with Cardiovascular and Non-Cardiovascular Outcomes: The Multi-Ethnic Study of Atherosclerosis

The American Journal of Cardiology

Publication date: Available online 23 June 2024 Source: The American Journal of Cardiology Author(s): Ebenezer Oni, Ellen Boakye, Gregg S. Pressman, Zeina Dardari, Kunal Jha, Moyses Szklo, Matthew Budoff, Khurram Nasir, Timothy M. Hughes, Michael J.

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Diltiazem, Direct Oral Anticoagulants and Risk of Major Bleeding in Patients with Atrial Fibrillation

HeartRhythm

Direct oral anticoagulants (DOACs) are the preferred anticoagulant strategy for stroke prevention in patients with atrial fibrillation. Concomitantly, non-dihydropyridine (non-DHP) calcium channel blockers (CCBs) and beta-blockers are commonly utilized for rate control in this cohort. Existing research has shown a potential increase in bleeding risk associated with administering non-DHP CCBs with anticoagulants; however, these findings remain tentative, attributed to variations in study design,

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Veno-venous extracorporeal membrane oxygenation for perioperative management of infective endocarditis after COVID-19 with acute respiratory distress syndrome: a case report

Journal of Cardiothoracic Surgery

Infective endocarditis (IE) is a rare cardiovascular complication in patients with coronavirus disease 2019 (COVID-19).

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Catheter Ablation Guided by Intracardiac Echocardiography: The “ICE” Age During Global Warming

HeartRhythm

Catheter ablation has become the most effective rhythm control strategy in treating atrial fibrillation (AF), preventing AF recurrence and delaying its progression to persistent AF better than antiarrhythmic drugs. Furthermore, among patients with heart failure, both reduced and preserved ejection fraction, catheter ablation reduces heart failure hospitalizations and mortality.

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July 2024 Stroke Highlights

Stroke Journal

Stroke, Volume 55, Issue 7 , Page 1729-1729, July 1, 2024.

Stroke 40
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Stroke Literature Synopsis (Clinical)

Stroke Journal

Stroke, Volume 55, Issue 7 , Page e189-e190, July 1, 2024.

Stroke 40
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Correction to: Advances in Primordial, Primary, and Secondary Prevention of Stroke in Diverse Populations

Stroke Journal

Stroke, Volume 55, Issue 7 , Page e235-e235, July 1, 2024.

Stroke 40
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Correction to: Association of Intravenous Alteplase, Early Reperfusion, and Clinical Outcome in Patients With Large Vessel Occlusion Stroke: Post Hoc Analysis of the Randomized DIRECT-MT Trial

Stroke Journal

Stroke, Volume 55, Issue 7 , Page e234-e234, July 1, 2024.

Stroke 40
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Correction to: CCR5 Activation Promotes NLRP1-Dependent Neuronal Pyroptosis via CCR5/PKA/CREB Pathway After Intracerebral Hemorrhage

Stroke Journal

Stroke, Volume 55, Issue 7 , Page e232-e232, July 1, 2024.

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Correction to: Uncommon Causes of Nontraumatic Intracerebral Hemorrhage

Stroke Journal

Stroke, Volume 55, Issue 7 , Page e231-e231, July 1, 2024.