Sat.Oct 26, 2024 - Fri.Nov 01, 2024

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Kidney Compass: Semaglutide for Nondiabetic Kidney Disease, with Hiddo Heerspink, PhD, PharmD, at Kidney Week 2024

HCPLive

Hiddo Heerspink, PhD, PharmD, joins the podcast during Kidney Week 2024 to discuss the SMART trial and the potential of semaglutide in people with kidney disease without diabetes.

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Standing desks are not the answer to decreasing blood pressure, clinical trial shows

Medical Xpress - Cardiology

Alternating between sitting and standing at work decreases sedentary behavior, but it has no effect on lowering blood pressure, according to a study led by a West Virginia University epidemiologist. Researchers also found that too much standing during work may have negative effects on cardiovascular health.

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ASA Advises No Longer Holding GLP-1 Agents Prior to Surgery for Most Patients

Med Page Today

(MedPage Today) -- Most patients should not stop taking GLP-1 receptor agonists prior to elective surgery, according to updated guidance from several medical societies, including the American Society of Anesthesiologists (ASA). This recommendation.

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One Of The Biggest Impact Things You Can Do To Live Longer.

Dr. Paddy Barrett

“But what can I do to make a difference?” This is one of the most common questions I get as a cardiologist when talking about preventing heart disease and living longer. As a doctor, there are many things I can do, and only a doctor can do: Prescribe medications Order certain diagnostic tests. Perform or arrange medical procedures. And so on.

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Prehospital activation: De-activated on ED arrival by Cardiologist because "It's not a STEMI"

Dr. Smith's ECG Blog

This was submitted by a paramedic, Hailey Kennedy A late 50s male called 911 following 2 hours of chest pain that started while working at his desk. He reported the crushing chest pain radiated down his left arm. Pt took an antacid with no relief and decided to call at the request of his wife. Here is his EMS ECG: What do you think? This was sent to me with no clinical information, and my initial impression viewing it on my phone was "It’s a tricky one.

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ECG Blog #454 — Look for the "Break".

Ken Grauer, MD

I was sent this ECG recording — and asked for my interpretation of the rhythm in Figure-1. I had little clinical information. QUESTIONS: How was I able to guess the probable correct answer in less than 5 seconds? How was I then able to prove that my guess was correct? Figure-1: The initial ECG in today's case. ( To improve visualization — I've digitized the original ECG using PMcardio ).

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Omega-3 Supplements Show Benefit in APOE4 Carriers

Med Page Today

(MedPage Today) -- High-dose supplements of docosahexaenoic acid (DHA), an omega-3 fatty acid, penetrated the brain in both APOE4 carriers and non-carriers before dementia onset, the placebo-controlled PreventE4 trial showed. The treatment did.

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More Trending

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Long COVID inflammation damages the heart, study finds

Science Daily - Heart Disease

New research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

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Heart signals brain to boost sleep for healing after heart attack, study finds

Medical Xpress - Cardiology

A heart attack can trigger a desire to get more sleep, allowing the heart to heal and reduce inflammation—and this happens because the heart sends special signals to the brain, according to a new Mount Sinai study.

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Cardiac Arrest Drug Administration Route a Toss Up

Med Page Today

(MedPage Today) -- Intraosseous vascular access for the administration of epinephrine during out-of-hospital cardiac arrest wasn't better than going for the veins first, two separate randomized trials showed. In the PARAMEDIC-3 trial conducted.

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Stress Triggers IBS Symptoms, Impacts Quality of Life More Than Diet, Study Finds

HCPLive

Mohammad Abuassi, MD, explains how classifying IBS based on triggers can aid the development of effective, personalized approaches to management.

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Low-level lead poisoning is still pervasive in the US and globally

Science Daily - Heart Disease

Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.

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Can you treat Non-STEMI with thrombolytics if it is OMI (Occlusion MI)? Of course!

Dr. Smith's ECG Blog

This case was sent by an old residency friend, Kirk Lufkin. He works in a small hospital in Northern Michigan. Case A 61 year old female. hypertension no other past history presented with 30 minutes of fluctuating non-radiating heaviness in chest, with diaphoresis and nausea. VS normal. No cardiac past history. Here is her ECG: What do you think? There are inferior hyperacute T-waves (diagnostic of inferior OMI), with 1) reciprocal ST depression in aVL, 2) a reciprocally inverted hyperacute T-wa

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Weight Loss After Bariatric Surgery in Teens Persisted at 10 Years

Med Page Today

(MedPage Today) -- For adolescents, weight loss after bariatric surgery was durable out to 10 years, data from the Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study confirmed. Among 260 adolescents who underwent bariatric surgery.

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Methods to Manage Psoriasis Using Oral Therapies, with Andrea Murina, MD

HCPLive

In her Fall Clinical interview, Murina highlighted several key takeaways related to her talk titled ‘Managing Psoriasis with Oral Therapy: 2024 & Beyond.

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Researchers identify 'sweet spot' for safe surgery after heart attack

Science Daily - Heart Disease

New research suggests older adults wait 3-6 months after a heart attack before elective noncardiac surgery to reduce the risk of serious complications like stroke or another heart attack.

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Long COVID inflammation damages the heart, blood analysis finds

Medical Xpress - Cardiology

University of Queensland-led research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

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Colchicine Goes Belly-Up in a More Definitive Heart Attack Trial

Med Page Today

(MedPage Today) -- Any cardiovascular protection from colchicine in heart attack survivors seemed to be debunked with a better-powered randomized trial, researchers found. Between acute MI patients randomized to colchicine or placebo right after.

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ESSENCE: Semaglutide Improves Fibrosis, Resolves Steatohepatitis in MASH

HCPLive

Headline results from part 1 of the phase 3 ESSENCE trial highlight semaglutide 2.4 mg’s benefits for fibrosis and steatohepatitis in patients with MASH.

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50 top hospitals for vascular surgery: Healthgrades

Becker's Hospital Review - Cardiology

Healthgrades published its 2025 Specialty Excellence Awards recipients Oct. 22. Of those recipients, 50 hospitals were recognized for delivering superior clinical outcomes in vascular surgery.

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The clinical effect of thoracoscopic segmentectomy in the treatment of lung malignancies less than 2CM in diameter

Journal of Cardiothoracic Surgery

To investigate the clinical effect of thoracoscopic segmentectomy in the treatment of lung malignancies less than 2CM in diameter. In this retrospective study, a total of 103 patients with lung cancer who received outpatient or inpatient treatment from December 2020 to May 2022 were selected and divided into the lobectomy group (n = 48) and the segmentectomy group (n = 55) according to different surgical methods.

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Major Win for Preemptive TAVR in Symptomless Aortic Stenosis

Med Page Today

(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.

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Depagliflozin Lowers Risk of Decline in Late-Stage Kidney Disease

HCPLive

The dapagliflozin group had an average eGFR rate of -2.24 mL/min/1.73 m2 compared to -3.67 mL/min/1.73 m2 in the control group after about 1.5 years of follow-up.

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Standing desks are bad for your health, according to a new study

Medical Xpress - Cardiology

The global market for standing desks is booming, projected to reach US$12.6 billion by 2032 (£9.7 billion). These desks have been hailed as a simple fix for the health risks associated with sitting all day. However, recent research suggests that standing might not be the health booster many hoped for.

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MASH and Cardiometabolic Health: Practical Treatments for Managing Complex Patients (Part 1) 

Cardiometabolic Health Congress

November is National Diabetes Month , and with the increasing overlap between type 2 diabetes (T2D) and metabolic dysfunction-associated steatohepatitis (MASH) , it’s critical to focus on integrating liver health into the management of cardiometabolic patients. This two-part series breaks down key treatment approaches for MASH, helping healthcare providers stay informed and deliver evidence-based care.

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Heart Attack Patients Who Receive Heparin ASAP Are Better Primed for Cath Lab

Med Page Today

(MedPage Today) -- The heparin frequently given before percutaneous coronary intervention (PCI) should be pushed to as early as possible in patients with ST-segment elevation myocardial infarction (STEMI), according to findings from the Chinese.

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Violeta Popov, MD, PhD: Do GLP-1 RAs Need to Be Held Before Endoscopy?

HCPLive

Popov reviews findings from her late-breaking presentation at ACG 2024 suggesting GLP-1 RAs may not need to be held prior to upper endoscopy.

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Microaxial Flow Pump Effects in Infarct-Related Cardiogenic Shock

JAMA Cardiology

This substudy of the Danish-German (DanGer) Shock randomized clinical trial investigates if the use of a microaxial flow pump reduces the need for pharmacological support and what the effects are on hemodynamics and lactate clearance in patients with ST-elevation myocardial infarction–induced cardiogenic shock.

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Chest pain and Saddleback STE. For Which of these 6 Cases should we Activate the cath lab? And how does the Queen of Hearts perform?

Dr. Smith's ECG Blog

Smith Introduction: Saddleback ST Elevation is often an OMI mimic, so one needs to scrutinize these ECGs!! Written by Magnus Nossen Below are ECGs from six different patients. All of the patients contacted EMS due to acute onset chest pain. Imagine you get these ECGs in real time and you are asked whether or not the cath lab should be activated? All ECGs in this case have saddleback ST elevation.

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Going Beyond Hearing Aids for Equal Care Access

Med Page Today

(MedPage Today) -- As a physician who is hard of hearing, I was excited to learn about FDA's authorization of Apple's newest AirPods, which will come with the capability to convert into hearing aids. If the AirPods live up to their promise, individuals.

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Prior Authorization Managers, Care Management Homes Could Expedite IBD Care

HCPLive

A retrospective review of a community-based practice provides insights into navigating setbacks in IBD care initiation due to insurance requirements.

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Targeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis

Journal of Clinical Investigation - Cardiology

Multiple sclerosis (MS) is a chronic disease characterized by dysregulated self-reactive immune responses that damage the neurons’ myelin sheath, leading to progressive disability. The primary therapeutic option, immunosuppressants, inhibits pathogenic anti-myelin responses but depresses the immune system. Antigen-specific monocyte-derived autologous tolerogenic dendritic cells (tolDCs) offer alternative therapeutic approaches to restore tolerance to autoantigens without causing generalized immu

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Brighter nights and darker days could lead to an early grave

Science Daily - Stroke

A study of more than 13 million hours of data, collected from light sensors worn by 89,000 people, has found exposure to bright nights and dark days is associated with an increased risk of death.

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Wegovy Cut Albuminuria by Half in Non-Diabetic CKD

Med Page Today

(MedPage Today) -- SAN DIEGO -- Semaglutide (Wegovy) reduced albuminuria in patients with overweight or obesity and chronic kidney disease (CKD) but without type 2 diabetes, a randomized trial showed. Among 101 patients, those who received 2.

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Exploring the Cardiovascular Benefits, Potential of Finerenone

HCPLive

In the final part of this 5-part series, Lala-Trindade discusses the findings of the FINEARTS-HF trial and how it might inform use of finerenone.

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Study shows no difference between two common methods for saving lives during cardiac arrest

Medical Xpress - Cardiology

There is no difference in the effectiveness of the two most commonly used methods for administering medication during out-of-hospital cardiac arrest.

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TET3-overexpressing macrophages promote endometriosis

Journal of Clinical Investigation - Cardiology

Endometriosis is a debilitating, chronic inflammatory disease affecting approximately 10% of reproductive-age women worldwide with no cure. While macrophages have been intrinsically linked to the pathophysiology of endometriosis, targeting them therapeutically has been extremely challenging due to their high heterogeneity and because these disease-associated macrophages (DAMs) can be either pathogenic or protective.

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