JAMA Cardiology
JUNE 10, 2025
This cross-sectional study investigates the magnitude of variability in the patterns of care in patients with ST-elevation myocardial infarction (STEMI) by hospital performance, location, or primary percutaneous coronary intervention volume and the association of these patterns with outcomes.
Circulation
JUNE 12, 2025
Circulation, Ahead of Print. Intraoperative transesophageal echocardiography is used with increasing frequency in cardiac surgery for monitoring and diagnostic purposes. Recent data have shown the impact of improved outcomes in patients undergoing cardiac surgery and the use of intraoperative transesophageal echocardiography in managing complex surgical decisions.
Frontiers in Cardiovascular Medicine
JUNE 10, 2025
BackgroundMajor adverse cardiac and cerebrovascular events (MACCE) following noncardiac surgery are the main cause of perioperative mortality. However, there are few evidence-based prediction models available for predicting the risk of MACCE. We aimed to analyze the risk factors of MACCE in patients aged 90 and older and to construct a prediction model, ultimately leading to the development of a nomogram.MethodsThis review study included clinical data from 872 patients aged 90 and older who unde
HCPLive
JUNE 9, 2025
News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
CardiacWire
JUNE 11, 2025
Bringing a more effective BP therapy to the U.S. market, the FDA approved George Medicines’ triple therapy polypill called Widaplik for patients with hypertension, making it the first of its kind to go to market in the U.S. The AHA estimates that more than 122M adults have high blood pressure in the U.S., and nearly 40% aren’t aware of it. George’s Widaplik contains the ARB telmisartan, calcium-channel blocker amlodipine, and diuretic indapamide, combining the three for effective BP management.
Journal of the American Heart Association
JUNE 11, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundPatients with both peripheral artery disease (PAD) and coronary artery disease are at heightened risk for adverse cardiovascular outcomes. Although long‐term risk has been well documented, contemporary in‐hospital outcomes for patients with PAD presenting with acute myocardial infarction (AMI) are less well characterized.MethodsWe analyzed 493 740 AMI hospitalizations from 670 US sites in the NCDR (National Cardiovascular Data
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
JUNE 8, 2025
News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol
Stroke Journal
JUNE 9, 2025
Stroke, Ahead of Print. Software programs leveraging artificial intelligence to detect vessel occlusions are now widely available to aid in stroke triage. Given their proprietary use, there is a surprising lack of information regarding how the software works, who is using the software, and their performance in an unbiased real-world setting. In this educational review of automated vessel occlusion software, we discuss emerging evidence of their utility, underlying algorithms, real-world diagnost
Journal of the American Heart Association
JUNE 11, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundCoronary artery bypass grafting (CABG) has been associated with reduced mortality, myocardial infarction, and repeat revascularization compared with percutaneous coronary intervention (PCI) for patients with 3‐vessel coronary artery disease (CAD) and diabetes. The majority of previous studies have been limited to follow‐up of <10 years.
Frontiers in Cardiovascular Medicine
JUNE 13, 2025
BackgroundSubendocardial myocardial infarction (SEMI) represents a more severe form of myocardial infarction. Currently, there lacks a comprehensive clinical index for predicting mortality in cases of subendocardial myocardial infarction. The objective of our study was to develop and evaluate a nomogram for predicting the 28-day risk of mortality among patients with SEMI.MethodsPatients diagnosed with subendocardial infarction were identified from the MIMIC-III database based on ICD-9 codes.
DAIC
JUNE 12, 2025
tim.hodson Thu, 06/12/2025 - 16:19 June 04, 2025 — HeartSciences Inc. has announced that the U.S. Food and Drug Administration has granted Breakthrough Device designation for its Aortic Stenosis (“AS”) ECG algorithm. Aortic Stenosis is one of the most serious and common heart valve diseases, often progressing silently and leading to severe, life-threatening outcomes if left undetected.
Heart BMJ
JUNE 13, 2025
Background Iron deficiency (ID) is common in patients with atrial fibrillation/flutter (AF), but its prognostic implications and optimal diagnostic criteria, particularly in those with and without heart failure (HF), remain unclear. This study assessed the associations between different ID definitions and clinical outcomes in patients with AF. Methods This Danish nationwide cohort study included 10 834 patients with AF who underwent iron studies between 2008 and 2019, stratified by HF status.
HCPLive
JUNE 11, 2025
A panelist discusses how spironolactone is typically the first fourth medication added for resistant hypertension but has limitations in patients with kidney disease or electrolyte issues, necessitating alternative strategies like renal denervation and highlighting the need for multiple treatment approaches to avoid polypharmacy-related adherence problems.
Frontiers in Cardiovascular Medicine
JUNE 13, 2025
ObjectivesMitral valve replacement in young children is a challenging situation due to limited options. In this study, we aimed to present the results of our patients who underwent mitral valve replacement using Melody (Medtronic Inc) and Sapien 3 (Edwards Inc) valves.MethodsWe performed a total of 18 mitral valve replacements at Phoenix Children's between 2017 and 2024.
DAIC
JUNE 11, 2025
As healthcare systems continue to shift toward value-based care and proactive disease management, remote monitoring has become a cornerstone of chronic care delivery —especially in cardiology. Among patients with implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy devices (CRT-Ds), real-time monitoring offers the promise of earlier intervention, reduced hospitalizations and better quality of life.
Heart BMJ
JUNE 13, 2025
Background Frailty is an independent risk factor for cardiovascular events. It is uncertain whether frailty modifies the efficacy of intensive blood pressure (BP) control among participants with type 2 diabetes mellitus(T2DM). Methods The Action to Control Cardiovascular Risk in Diabetes Blood Pressure (ACCORD BP) trial, a two-by-two factorial trial, examined the effects of systolic BP (<120 vs <140 mm Hg) and glycaemic control on cardiovascular events in T2DM.
Medical Xpress - Cardiology
JUNE 13, 2025
An international study has shown that targeted online education on atrial fibrillation (AF) for health professionals can improve guideline-adherent care. This cluster-randomized controlled trial, published in Nature Medicine this week, was designed to test if structured online AF education for health professionals could improve the care that individual patients receive.
Frontiers in Cardiovascular Medicine
JUNE 13, 2025
ObjectiveThis study aims to investigate the role of perivascular adipose tissue (PVAT) attenuation in predicting residual false lumen formation following thoracic endovascular aortic repair (TEVAR) in patients with Stanford Type B aortic dissection (TBAD). The focus is on the association between PVAT attenuation (HUΔand HUratio) and postoperative outcomes, particularly the development of residual false lumen.MethodsA retrospective analysis was conducted on 132 patients who underwent TEVAR for TB
Journal of Cardiovascular Electrophysiology
JUNE 12, 2025
ABSTRACT Background There are few comparative studies on the everyday clinical outcomes of commercially available pulsed field ablation (PFA) systems for atrial fibrillation (AF). Objective This study evaluates the acute efficacy and safety outcomes of the FARAPULSE™ (pentaspline catheter) and PulseSelect™ (circular catheter) system. Methods International, multicenter, registry on patients with paroxysmal or persistent AF, undergoing a first ablation using either PFA system between January 29th,
The British Journal of Cardiology
JUNE 10, 2025
Myocardial fibrosis is a common pathological process associated with various cardiovascular diseases, contributing to adverse cardiac remodelling and increased morbidity. Angiotensin-converting enzyme inhibitors (ACEi) have been widely used for myocardial protection in high-risk patients. However, there are no clear recommendations for their use for the prevention of fibrosis after myocardial injury.
Medical Xpress - Cardiology
JUNE 10, 2025
Researchers have developed a novel method for simultaneously recording action potentials (APs)—temporary changes in electrical potential when cells become excited—and calcium transients—calcium fluctuations that drive muscle contraction—in single cardiomyocytes (heart muscle cells) derived from iPS cells.
Frontiers in Cardiovascular Medicine
JUNE 12, 2025
IntroductionThe surgical and medical management of aging patients with adult congenital heart disease (ACHD) continues to innovate to meet the evolving needs of this unique patient population, leading to improved life expectancy and quality of life. However, the ACHD population is characterized by high morbidity and mortality. With this study, we aim to describe patient characteristics and surgical outcomes for the over fifty ACHD cardiac surgical cohort, focusing on risk factors for mortality a
Med Page Today
JUNE 9, 2025
(MedPage Today) -- The FDA approved a polypill containing telmisartan, amlodipine, and indapamide, known as Widaplik, for the treatment of hypertension in adults, including as initial treatment. This marks the first time that a triple combination.
Circulation: Arrhythmia and Electrophysiology
JUNE 11, 2025
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Mitral isthmus (MI) gap conduction is common despite ethanol infusion into the vein of Marshall (EI-VOM) and endocardial ablation of the MI. This study aimed to investigate the characteristics of electrograms of the distal coronary sinus (CSd) to guide the identification of the gap location in the MI.METHODS:A total of 187 patients who underwent EI-VOM and MI ablation were included in the study.
Medical Xpress - Cardiology
JUNE 13, 2025
A new lab-grown material has revealed that some of the effects of aging in the heart may be slowed and even reversed. The discovery could open the door to therapies that rejuvenate the heart by changing its cellular environment, rather than focusing on the heart cells themselves.
Frontiers in Cardiovascular Medicine
JUNE 12, 2025
IntroductionAcute ST-elevation myocardial infarction (STEMI) is a frequent and serious presentation of acute coronary syndrome. The STOP-SCA+ study aimed to (i) describe 1-year compliance to secondary prevention cardiac tri-therapy and (ii) identify factors associated with negative outcomes 1 year after STEMI, particularly the impact of compliance and rehabilitation care.MethodsPatients who were >18 years old and hospitalized for STEMI in five interventional cardiac centers with the same cardiac
Dr. Smith's ECG Blog
JUNE 7, 2025
A middle-aged man with a history of HOCM presented with 24 hours of chest pain, still active. He stated that he had been dehydrated for a day as well. The pain was not at all severe, and localized to the left sternal border, without radiation. The patient was in no distress and had normal vital signs. Here is his presentation ECG: What do you think?
European Journal of Cardiovascular Nursing
JUNE 12, 2025
Abstract Aim To assess the effects of organised clinical service delivery models for AF on all-cause mortality and hospitalisation, as well as cardiovascular outcomes, thromboembolic events, bleeding complications, quality of life, symptom burden, healthcare costs, and length of hospital stay. Methods and Results A systematic search was conducted across several databases, including Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and CINAHL, and clinical trial registrie
The British Journal of Cardiology
JUNE 10, 2025
Cardiac rehabilitation (ExCR) is an essential, evidence-based part of the management of people with chronic heart failure (CHF), but research indicates it is underused. This retrospective audit explores the eligibility of heart failure inpatients for ExCR, according to the European Society of Cardiology (ESC) consensus statement, and the impact of frailty on referral rates.
Frontiers in Cardiovascular Medicine
JUNE 9, 2025
BackgroundFamilial hypercholesterolaemia (FH) is characterised by significantly elevated low-density lipoprotein cholesterol (LDL-C) levels and early-onset coronary artery disease. Additionally, clopidogrel resistance is observed in approximately 30%–50% of individuals globally. Among FH patients with early-onset coronary artery disease, inadequate LDL-C management and suboptimal antiplatelet therapy after stent implantation are key factors contributing to recurrent in-stent restenosis (ISR).Cas
The American Journal of Cardiology
JUNE 8, 2025
Publication date: Available online 8 June 2025 Source: The American Journal of Cardiology Author(s): Zade Bihag, Jay Patel, Jeff F. Mather, Robert Hagberg, Jawad Haider, Talhat Azemi, Immad Sadiq, Mohiuddin Cheema, Bryan Piccirillo, Sheelagh Pousatis, Priyesh Thakurathi, David Yaffee, Sabet W. Hashim, Raymond G.
Circulation: Genomic and Precision Medicine
JUNE 13, 2025
Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Pathogenic variants in thelamin A/C(LMNA) gene cause an aggressive form of dilated cardiomyopathy (DCM), marked by higher rates of advanced conduction disease, malignant ventricular tachyarrhythmias, and advanced heart failure compared with other causes of nonischemic cardiomyopathy.
Medical Xpress - Cardiology
JUNE 10, 2025
Heating the lower limbs before exercise has been found to significantly improve endurance in individuals with heart failure.
Frontiers in Cardiovascular Medicine
JUNE 13, 2025
BackgroundPost-cardiotomy cardiogenic shock (PCCS) is a serious condition that necessitates veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Although acute kidney injury (AKI) often complicates PCCS, its specific effects on patient outcomes remain unclear. This study seeks to evaluate the impact of AKI on 90-day mortality.MethodsThis retrospective study included 91 patients with postoperative cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation following cardi
HCPLive
JUNE 9, 2025
Phase 3 trials show enlicitide decanoate significantly lowers LDL cholesterol, offering a promising oral treatment for hyperlipidemia and cardiovascular risk.
Open Heart
JUNE 12, 2025
Background The detection of atrial fibrillation (AF) after a cryptogenic stroke (CS) carries important therapeutic implications. In this study, we aimed to accurately assess the incidence of AF among CS subjects by using an insertable cardiac monitor (ICM). Methods A prospective, single-arm, multicentre registry was conducted to identify AF in 155 CS subjects using the Confirm Rx ICM (Abbott, California, USA) across 20 global sites.
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