Sat.Sep 07, 2024 - Fri.Sep 13, 2024

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Direct-to-Consumer Drugs: Big Pharma's Digital Health Play

Med Page Today

(MedPage Today) -- More than a quarter of a century ago, the FDA eased regulations to make it easier for pharmaceutical companies to advertise directly to consumers. Today, it is nearly impossible to get through a family sitcom without hearing.

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Babies born to women consuming a high fat, sugary diet at greater risk of cardiovascular disease and diabetes in later life

Science Daily - Heart Disease

Babies born to pregnant women with obesity are more likely to develop heart problems and diabetes as adults due to fetal damage caused by the high-fat, high-energy diet of their mother.

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Semaglutide Reduces Rates of Cardiovascular, COVID-19-Related Deaths

HCPLive

Semaglutide lowers rates of cardiovascular and COVID-19-related deaths in patients with overweight/obesity, offering promising cardio-metabolic and non-cardiovascular benefits.

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Better cardiovascular health in early pregnancy may offset high genetic risk

American Heart News - Heart News

Research Highlights: Favorable cardiovascular health in early pregnancy, as measured by the American Heart Association's Life's Essential 8 (LE8) cardiovascular health score, was linked to lower risk of preeclampsia and gestational hypertension,

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Acute chest pain, right bundle branch block, no STEMI criteria, and negative initial troponin.

Dr. Smith's ECG Blog

Written by Pendell Meyers A man in his 40s called EMS for acute chest pain that awoke him from sleep, along with nausea and shortness of breath. His history included known heart failure with prior EF 18%, insulin dependent diabetes, and polysubstance abuse. Vitals were within normal limits except for tachypnea. Here are his EMS ECGs along with the Queen of Hearts interpretations below each one: EMS1 0650 EMS2 0707 Click here to sign up for Queen of Hearts Access The ECGs show RBBB and LAFB, with

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How many people have A-Fib? Three times more than we thought

Science Daily - Heart Disease

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5% of the population, or 10.5 million U.S. adults, according to new estimates.

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Cannabis Cream Safely Reduces Itch in Patients with CKD-Associated Pruritus

HCPLive

A new study found cannabis-containing cream may be effective at alleviating itch in patients with chronic kidney disease (CKD)-associated pruritus with no adverse events.

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An elderly male with shortness of breath

Dr. Smith's ECG Blog

A 70-something y.o. male presents to triage with shortness of breath. He reports significant chest pain at the base of his scapula on the right side along with new shortness of breath. ECG 1 at time zero EARLY REPOLARIZATION ABNORMAL ECG ED final official overread: "early repol vs hyperacute T, minimal changes from previous (previous shown below)" What do YOU think?

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Breakthrough is a game changer in heart valve technology

Science Daily - Heart Disease

When a patient needs a new heart valve, the current mechanical and tissue replacements each have strengths and weaknesses. Now, a team of researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing -- and life-saving -- for many.

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Texas cardiologist 1st in nation to place dual-chamber leadless pacemaker

Becker's Hospital Review - Cardiology

A cardiologist from the Heart and Vascular Institute at Longview (Texas) Regional Medical Center became the first in the nation to place a dual-chamber leadless pacemaker.

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Patients with IBS Report Treatment Dissatisfaction, Lack of Symptom Control

HCPLive

Findings highlight disease burden and ongoing unmet needs in patients with IBS-C and IBS-D, suggesting the benefit of prescription medications on rates of satisfaction and symptom control.

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Texted from a former EM resident: 70 yo with syncope and hypotension, but no chest pain. Make their eyes roll!

Dr. Smith's ECG Blog

A former resident texted me this case: "Hey Dr. Smith. Hope you’re doing well! How excited would you have been about this case?" Here is the case: Report from EMS was witnessed syncope, his son did CPR, but the patient had pulses when EMS arrived. When the patient arrived in the ED, he was still hypotensive in 70s, slowly improving with EMS fluids. No Chest Pain, but somnolent.

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Like father, like daughter

Science Daily - Heart Disease

When they become fathers, men who have an unhealthy, high-cholesterol diet can cause increased risk of cardiovascular disease, or CVD, in their daughters, a mouse study has found.

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Addison Gutierrez

Conquering CHD

The Warrior Heart Project Hi my name is Addison Gutierrez! On June 21, 2008 my mom went in for a routine ultrasound. She had low amniotic fluid which meant that she had to have an emergency C section. My dad was a surgery resident at the hospital so he was able to meet her there. I was born at 35 weeks with the lungs of a 28 week old and blue because of my lack of oxygen.

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Reagan Udall Foundation’s PTSD Meeting Was “Reassuring,” Says Healthcare Expert

HCPLive

HCPLive spoke to a healthcare expert who gave his thoughts on the Reagan Udall Foundation for the FDA’s recent meeting to discuss advancing treatments for PTSD.

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Researchers discover new target for treating heart failure: Protein kinase N

Medical Xpress - Cardiology

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the heart, known as fibrosis, is associated with the progression of heart failure. A group from the Nagoya University Graduate School of Medicine in Japan has found an enzyme protein kinase N (PKN) that regulates heart fibrosis. The enzyme catalyzes the conversion of heart fibroblasts to myofibroblasts, which threatens the integrity of the heart.

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A new app to 'uncuff' blood pressure monitoring

Science Daily - Heart Disease

Researchers have developed a groundbreaking smartphone app that measures blood pressure using a smartphone's built-in sensors, eliminating the need for traditional cuffs. This technology can make blood pressure monitoring more accessible and convenient, especially for underserved populations. By allowing users to measure their blood pressure anytime and anywhere, the app could revolutionize cardiovascular care and improve early detection of hypertension.

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8-Hour Eating Window Improved Glycemic Control, Small Study Shows

Med Page Today

(MedPage Today) -- Eating within an 8-hour window improved glycemic variability in adults at risk for type 2 diabetes, an interim analysis of a randomized crossover study of 15 people showed. Compared with eating over 14+ hours per day, eating.

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Spontaneous avulsion of left internal mammary artery graft a complication of coronary artery bypass surgery: case report and review of the literature

Journal of Cardiothoracic Surgery

Coronary artery bypass grafting (CABG) surgery is a common procedure for managing multi-vessel coronary artery disease to revascularize the myocardium. Among the various conduits used, the left internal mammar.

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Study Finds Traditional Risk Scores Miss Most Patients at Risk of First Heart Attack

HCPLive

New study finds ASCVD risk score often misses at-risk patients for first acute coronary syndrome, highlighting need for better prediction methods.

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Throat problems could impair autonomic nervous system's ability to regulate blood pressure

Science Daily - Heart Disease

Patients with throat problems were less able to regulate their blood pressure in a new study. The study shows reduced baroreflex sensitivity in patients with throat symptoms.

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Atheroimmunology: keeping the immune system in atherosclerosis in check

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 11 September 2024; doi:10.1038/s41569-024-01075-1 The immune response is not unlike a game of chess, with white and black pieces playing opposing roles and orchestrating an opening, a middle and an endgame of innate immunity, adaptive immunity and resolution, respectively. After decades of research, the study of atheroimmunology has brought the first therapeutics to the clinic.

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World Stroke Organization, Philips Release Paper on Expanding Access to Stroke Care

DAIC

tim.hodson Tue, 09/10/2024 - 13:18 Sept. 10, 2024 — Royal Philips and the World Stroke Organization (WSO) have published a policy paper calling for a revolution in stroke care to make a real difference to the lives of millions and bring significant economic benefits worldwide. Strokes affect an estimated 12 million people globally every year, including an increasing number of young people.

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HCV Viremic Donor Kidney Exposure Not Linked to Opportunistic Viral Infection

HCPLive

There was no difference in the incidence of BKPyV, CMV, or EBV in patients who received HCV NAT-positive donor kidneys versus those who received HCV NAT-negative donor kidneys.

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Experimental blood test predicts risk for developing COPD, other severe respiratory diseases

Science Daily - Heart Disease

A scientific team has created a preclinical blood test to identify adults most likely to develop severe respiratory conditions, including chronic obstructive pulmonary disease (COPD). The blood test analyzes 32 proteins that scientists determined accurately predicted an adult with an increased likelihood for requiring medical care for or dying from severe respiratory illness.

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EM Quick Hits 59 Traumatic Coronary Artery Dissection, Proper Use of Insulin, Mesenteric Ischemia, Exercise Associated Hyponatremia, AI for OMI

ECG Cases

On this month's EM Quick Hits podcast: Ian Chernoff on the often elusive diagnosis of traumatic coronary artery dissection, Anand Swaminathan on proper use of insulin in DKA and in hyperkalemia, Brit Long and Hans Rosenberg on mesenteric ischemia pearls and pitfalls in diagnosis and management, Dave Jerome on recognition and management exercise-associated hyponatremia and heat illness and Jesse McLaren on the Queen of Hearts AI model in helping identify occlusion MI on ECG.

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Foods with low Nutri-Scores associated with an increased risk of cardiovascular diseases

Medical Xpress - Cardiology

Cardiovascular diseases are the leading cause of mortality in Western Europe, accounting for 1/3 of deaths in 2019. Diet is thought to be responsible for around 30% of such deaths. Nutrition-related prevention policies therefore constitute a major public health challenge for these diseases.

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Why Insulin Resistance Is The Biggest Silent Risk Factor For Heart Disease.

Dr. Paddy Barrett

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Everyone sits somewhere on the scale of insulin sensitivity from very insulin sensitive to very insulin resistant at the point of type 2 diabetes. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers.

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Diagnostic tool identifies puzzling inflammatory diseases in kids

Science Daily - Heart Disease

RNA is expelled from cells via cell death or active release, and can then find its way into blood plasma. Medical researchers have now developed machine learning models that use these cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions that are difficult to differentiate. The diagnostic tool can accurately determine if a patient has Kawasaki disease (KD), Multisystem Inflammatory Syndrome in Children (MIS-C), a viral infection or a bacterial infection, while simultaneousl

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Study Reveals Research Gaps on Acute Pancreatitis in Sickle Cell Disease

HCPLive

A systematic review found a higher prevalence of acute pancreatitis in individuals with the HbSS genotype, though a meta-analysis could not be performed.

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A new app uses smartphone technology to 'uncuff' blood pressure monitoring

Medical Xpress - Cardiology

Researchers at the University of Pittsburgh are pioneering a new approach to blood pressure monitoring—using the devices we carry with us every day.

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Liraglutide Helped Cut BMI in Kids With Obesity as Young as 6

Med Page Today

(MedPage Today) -- Liraglutide (Saxenda) added to lifestyle intervention helped reduce BMI in young children with obesity, the phase IIIa SCALE Kids trial found. By week 56, kids, ages 6 to <12 years, on once-daily 3-mg liraglutide lost 5.8.

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Can having a stroke change your sleep?

Science Daily - Heart Disease

People who have had a stroke may be more likely to sleep too much or too little compared to those without prior stroke, according to a new study. The study does not prove that stroke causes abnormal sleep; it only shows an association.

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Transcutaneous Pacing: Part 3

EMS 12-Lead

Complete Heart Block with Altered Mental Status Josh Kimbrell, NRP @joshkimbre Judah Kreinbrook, EMT-P @JMedic2JDoc This is the third installment of a blog series showing how transcutaneous pacing (TCP) can be difficult and how you can improve your skills. We will be using information from different cases where paramedics attempted TCP in the field.

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Increased testing for heart disease indicator needed worldwide, say experts

Medical Xpress - Cardiology

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

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Effects of dietary interventions and intermittent fasting on HDL function in obese individuals with T2DM: a randomized controlled trial

Cardiovascular Diabetology

Cardiovascular disease represents a significant risk factor for mortality in individuals with type 2 diabetes mellitus (T2DM). High-density lipoprotein (HDL) is believed to play a crucial role in maintaining c.

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Study Identifies Link Between Maternal Bread Consumption, Risk of Infant Allergies

HCPLive

In this analysis, an increased risk of allergy and eczema was associated with bread and thiamine intake increases during pregnancy.

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