Sat.May 31, 2025 - Fri.Jun 06, 2025

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Type 2 diabetes worsens the outcome of ischemia/reperfusion in female STEMI patients and female db/db mice with HFpEF cardiometabolic phenotype

Cardiovascular Diabetology

Heart failure with preserved ejection fraction (HFpEF) poses a significant global health challenge, disproportionately affecting women. Diabetic women with HFpEF represent a high-risk subgroup, particularly af.

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AHA PREVENT and Lp(a) for Cardiovascular Disease Risk

JAMA Cardiology

This analysis of 2 cohort studies assesses whether adding lipoprotein(a) levels to the AHA PREVENT equations improved risk prediction of atherosclerotic cardiovascular disease.

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Semaglutide Linked to Age-Related Macular Degeneration Risk

Med Page Today

(MedPage Today) -- Older adults taking GLP-1 receptor agonists, primarily semaglutide (Rybelsus, Ozempic, Wegovy), had a small uptick in their risk of developing neovascular age-related macular degeneration (nAMD), according to a retrospective.

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Higher linoleic acid levels linked to lower heart disease and diabetes risk

Medical Xpress - Cardiology

New research that used blood markers to measure linoleic acid levels and their relation to cardiometabolic risk adds evidence that this omega-6 fatty acid may help to lower risks of heart disease and type 2 diabetes. The findings challenge claims that seed oils are harmful to cardiometabolic health.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Women with Premature Menopause Face Greater Cardiovascular Risks, Study Finds

HCPLive

News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol

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AHA PREVENT Equations With Lipoprotein(a) and Risk Assessment for Primary Prevention

JAMA Cardiology

Quantitative risk estimation is the starting point for decisions regarding use of drug therapy to reduce events in primary prevention of atherosclerotic cardiovascular disease (ASCVD). Equations that predict 10-year risk have steadily improved in their content, relevance, accuracy, and precision over time. When assessing the utility of risk equations for clinical practice, the metrics of discrimination, calibration, and reclassification are of paramount importance.

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Over-the-counter supplement could prevent heart disease in type 2 diabetes patients

Medical Xpress - Cardiology

A cheap over-the-counter supplement could hold the key to preventing heart failure in people with Type 2 diabetes, according to research presented Tuesday at the British Cardiovascular Society conference in Manchester.

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Don’t Miss a Beat: CONFIDENCE Trial and Combination T2D, CKD Therapy at Heart in Diabetes 2025

HCPLive

News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol

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ACC CardiaCast: Conversations in Heart Failure: Extrapolate With Caution: A STEMI Shock Reality Check

American College of Cardiology

In this episode, Drs. Jenna Skowronski, Francesco Castagna and Saraschandra Vallabhajosyula unpack how assumptions drawn from ST-segment elevation myocardial infarction (STEMI) data may be leading us astray in broader shock management.

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Two Drugs Better Than One for Easing Albuminuria in CKD Patients With Diabetes

Med Page Today

(MedPage Today) -- An SGLT2 inhibitor combined with a nonsteroidal mineralocorticoid receptor antagonist quickly cut urinary albumin-to-creatinine ratio (UACR) in patients with albuminuria and both chronic kidney disease (CKD) and type 2 diabetes.

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For heart health, food quality may matter more than cutting carbs or fat

Medical Xpress - Cardiology

A new study that followed almost 200,000 people for several decades has found that when it comes to heart health, the quality of food consumed matters as much as following a low-carbohydrate or low-fat diet. The results suggest that choosing healthy, high-quality foods is key to protecting the heart.

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Combination GIP/GLP-1 Agonism More Effectively Prevents Cardiovascular Events

HCPLive

News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol

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Cardiac Injury Detected by Smartwatch

The New England Journal of Medicine

A 76-year-old retired cardiovascular nurse presented to the ED with 2 hours of chest pain triggered by severe emotional distress and associated with changes in the electrocardiogram on her smartwatch.

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Young People Lead New Wave of Americans Unaware of Their Hypertension

Med Page Today

(MedPage Today) -- High blood pressure (BP) awareness increasingly slipped under the radar since the COVID-19 pandemic, according to nationally representative health data. Results from National Health and Nutrition Examination Survey (NHANES.

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Milli-spinner technique more than doubles success rate for blood clot removal

Medical Xpress - Cardiology

Researchers at Stanford have developed a new technology for removing blood clots that is more than twice as effective as current techniques. It could significantly improve success rates in treating strokes, heart attacks, pulmonary embolisms, and other clot-related diseases.

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CONFIDENCE: SGLT2i and Finerenone Effective, Safe to Initiate Simultaneously in CKD

HCPLive

Combination therapy with finerenone and empagliflozin significantly reduces urinary albumin levels in CKD patients.

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Contrast Use During PCI on the Decline

CardiacWire

New ACC registry data suggests interventional cardiologists are using less contrast for PCI procedures in the cath lab which helps reduce post-PCI acute kidney injury risks, but a deeper look tells us there’s still room for improvement. Iodinated contrast agents are commonly used for PCI with gadolinium-based contrast serving as an alternative but both can cause complications like acute kidney injury.

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Surgical Ablation During CABG Linked to Improved Survival in Patients with Preexisting Atrial Fibrillation

Society of Thoracic Surgeons - Congenital

Press Release Surgical Ablation During CABG Linked to Improved Survival in Patients with Preexisting Atrial Fibrillation June 4, 2025 KCummings Thu, 06/05/2025 - 12:56 CHICAGO (June 4, 2025) — A new study published in The Annals of Thoracic Surgery, a journal from The Society of Thoracic Surgeons, finds that Medicare patients with atrial fibrillation (AF) who undergo surgical ablation during isolated coronary artery bypass grafting (CABG) live longer than those who do not, offering compelling su

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Organoids containing blood vessels have been grown, holding promise for research and treatment

Medical Xpress - Cardiology

For over a decade, scientists have been growing organoids—small clusters of cells that mimic a particular organ—to serve as miniature biological models. Organoids of the brain have been used to study neurodevelopmental disorders; intestinal organoids, to model celiac disease; and lung organoids, to investigate SARS-CoV-2. Heart organoids have even been sent to space to test the effect of microgravity on cardiac muscle.

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Asthma, Peanut Exposure Linked to Increased Risk of Fatal Food Anaphylaxis

HCPLive

Asthma and peanuts were identified as key risk factors for grade 4 anaphylaxis in a retrospective study, highlighting the need for tailored prevention.

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Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report

Frontiers in Cardiovascular Medicine

BackgroundGuideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) has been demonstrated to significantly reduce morbidity and mortality. However, many patients, especially those with advanced HFrEF, are unable to tolerate optimal GDMT due to hypotension. Cardiac contractility modulation (CCM) is a novel therapeutic approach that enhances myocardial contractility and reverses cardiac remodeling, thereby improving cardiac function and quality of life

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Think Aorta: aortic dissection awareness and perspectives from the patient

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 03 June 2025; doi:10.1038/s41569-025-01177-4 Aortic dissection has long been considered a rare, unpreventable and inevitably fatal disease. However, recent advances now prove otherwise. The patient-led Think Aorta campaign is challenging old thinking, improving diagnosis and advocating for better care, such as family screening.

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Why a heart attack can cause ventricular fibrillation

Medical Xpress - Cardiology

Many people who have suffered a heart attack subsequently develop life-threatening complications like ventricular fibrillation. Now an international research team from the University of Freiburg's Faculty of Medicine and Dalhousie University Halifax in Canada have found out why this is the case.

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Study Highlights Cardiopulmonary Benefits of GLP-1 RAs in Patients with Diabetes, OSA

HCPLive

New research has indicated that glucagon-like peptide-1 receptor agonists result in lower all-cause mortality and risk of cardiovascular events in patients with concurrent sleep apnea and type 2 diabetes.

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Health Warnings on E-Cigarettes May Improve Perception of Risks

Med Page Today

(MedPage Today) -- Words that cautioned about the health effects of e-cigarettes increased beliefs in the harms associated with these tobacco products, a meta-analysis showed, supporting additional warnings beyond nicotine addiction. Text-only.

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Leadless and extravascular cardiac resynchronization therapy: the future for CRT?

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 06 June 2025; doi:10.1038/s41569-025-01178-3 Cardiac resynchronization therapy is used to treat dyssynchronous heart failure. Lead-related complications and anatomical constraints can limit pacing lead placement, but leadless systems are now becoming available. These new systems overcome lead-related issues, offering a new option for patients with complex disease (such as congenital heart disease) by eliminating intravascular hardware.

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Wildfire smoke may silently threaten heart health far beyond fire zones

Medical Xpress - Cardiology

Smoke from Canada wildfires is rapidly drifting into the U.S. and the American Heart Association, a global force changing the future of health for all, warns that this wildfire smoke exposure may pose an increased risk for heart disease.

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Phase 3 ORIGIN Sets Stage for Atacicept in IgA Nephropathy, with Richard Lafayette, MD

HCPLive

News Media Podcasts State Of Sciences - Presentations Videos Webinars Multimedia Series CURE Connections® Insights Medcast Peer Exchange Peers & Perspectives Special Report Conferences Conference Coverage Conference Listing Partners CME/CE Resources Digital Supplements Interactive Tools Live Events Press Release Publications Sponsored Advisory Board Subscribe Choose Specialty Allergy Allergy Allergy Allergy Biosimilars Cardiology Cardiology Cardiology Cardiology Cardiology Cardiology Cardiol

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A retrospective cross-sectional study of association between triglyceride-glucose index and carotid atherosclerosis

Frontiers in Cardiovascular Medicine

BackgroundThe triglyceride-glucose (TyG) index, a simple surrogate marker of insulin resistance (IR), has been associated with cardiovascular risk factors and atherosclerosis. However, its relationship with carotid atherosclerosis (CA), including carotid intima thickening (CMT), plaques, and stenosis, remains inadequately studied in the general population.PurposeThis study aimed to evaluate the association between the TyG index and CA.MethodsA retrospective cross-sectional study was conducted am

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New Study: GLP-1 Medications Decrease Risk of Major Cardiovascular Events

DAIC

tim.hodson Fri, 06/06/2025 - 14:01 June 6, 2025 – A large retrospective review of more than 100,000 patients found the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in moderate peripheral artery disease (PAD) is associated with a decreased rate of cardiovascular events, major limb events and inpatient admissions. This is the first retrospective trial to evaluate the clinical impact of GLP-1 RAs for patients with moderate PAD.

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Engineered with heart: Student-designed device could streamline imaging for cardiac procedures

Medical Xpress - Cardiology

Irregular heartbeats affect more than 4 million Americans, and for many, the treatment is cardiac ablation—a procedure that uses long, flexible catheters inserted through blood vessels to modify small areas of the heart and restore a normal rhythm. It is a routine yet delicate procedure that requires constant real-time ultrasound imaging from within the heart.

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Atopic Disorders Linked to Increased Risk of Mental Illness in UK Cohort Study

HCPLive

UK study finds atopic conditions, especially anaphylaxis, significantly raise the risk of anxiety, depression, OCD, and other mental illnesses in primary care patients.

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Left atrial pressure and significant tricuspid regurgitation in persistent atrial fibrillation

Frontiers in Cardiovascular Medicine

IntroductionAtrial fibrillation (AF) is a well-established contributing factor to isolated tricuspid regurgitation (TR), with elevated left atrial pressure (LAP) playing a crucial role in disease progression and patient outcomes. We investigated the relationship between LAP and TR in patients with AF.MethodsWe enrolled individuals diagnosed with AF who underwent LA appendage closure at two centers in China, between January 2015 and December 2023.

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Study Finds Surgical Ablation During CABG Linked to Improved Survival in Patients with Preexisting Atrial Fibrillation

DAIC

tim.hodson Wed, 06/04/2025 - 16:27 June 4, 2025 A new study published in The Annals of Thoracic Surgery, a journal from The Society of Thoracic Surgeons, finds that Medicare patients with atrial fibrillation (AF) who undergo surgical ablation during isolated coronary artery bypass grafting (CABG) live longer than those who do not, offering compelling support for clinical guidelines that recommend this procedure but are too often not followed in practice.

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Treatment with orforglipron, an oral glucagon like peptide-1 receptor agonist, is associated with improvements of CV risk biomarkers in participants with type 2 diabetes or obesity without diabetes

Cardiovascular Diabetology

Orforglipron, a novel oral, non-peptide glucagon like peptide-1 (GLP-1) receptor agonist, has demonstrated efficacy in improving body weight reduction and glycemic control. However, its potential benefits in i.

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Common Diabetes Treatment May Cause Neovascular Age-Related Macular Degeneration

HCPLive

GLP-1 RAs, one of the most common medications for obesity and diabetes, have several inherent risks that are often overlooked in favor of their efficacy.