Sat.Aug 24, 2024 - Fri.Aug 30, 2024

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ECG Blog #445 — VT or LBBB?

Ken Grauer, MD

The ECG in Figure-1 was obtained from an 80-year old woman — who presented to the ED ( E mergency D epartment ) — with a several hour history of "palpitations" and CP ( C hest P ain ). She was hemodynamically stable at the time ECG #1 was recorded. QUESTIONS: The ECG in Figure-1 was seen by a number of physicians — the majority of whom thought the rhythm was some form of SVT ( S upra V entricular T achycardia ) with LBBB ( L eft B undle B ranch B lock ) aberration.

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Wegovy Protects Against Deadly COVID Cases

Med Page Today

(MedPage Today) -- LONDON -- The clinical benefits of semaglutide (Wegovy) went beyond expectations in the SELECT trial, given the reductions in non-cardiovascular and infectious disease deaths observed. Among people with overweight or obesity.

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These areas have the US' highest cardiac death rate

Becker's Hospital Review - Cardiology

High-poverty rural regions in the Southern U.S. have the highest cardiovascular disease-associated death rate, according to a report published Aug. 16 in the Journal of Rural Health.

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Topical Roflumilast 0.3% Superior to Vehicle in Treating Plaque Psoriasis

HCPLive

In this systematic review and meta-analysis, the investigators highlighted topical roflumilast’s success in clinical milestones such as IGA and PASI score success.

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Study shows reduced inflammation in residents after adding trees to their neighborhoods

Science Daily - Heart Disease

A new project has found that people living in neighborhoods where the number of trees and shrubs was more than doubled showed lower levels of a blood marker of inflammation than those living outside the planted areas. General inflammation is an important risk indicator for heart disease and other chronic diseases.

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Experts: Don't Say 'Heartbeat' to Describe Ultrasound Findings in Early Pregnancy

Med Page Today

(MedPage Today) -- Some terms commonly used to describe observations seen on ultrasound during first-trimester pregnancies are outdated and should be replaced with more descriptive language, a multisociety panel of ob/gyns, radiologists, and emergency.

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GLP-1s reduce cardiovascular mortality: Study

Becker's Hospital Review - Cardiology

GLP-1s reduced mortality and complications from cardiovascular events, according to a study published Aug. 22 in Diabetes, Obesity and Metabolism: A Journal of Pharmacology and Therapeutics.

More Trending

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Is long-term beta-blocker therapy needed after a heart attack?

Science Daily - Heart Disease

The appropriate duration of beta-blocker treatment after a heart attack (a myocardial infarction [MI]) is unknown in patients who do not need to take beta-blockers for another reason. In the ABYSS trial, the cardiovascular safety of interrupting beta-blocker could not be shown in comparison with beta-blocker continuation and beta-blocker interruption did not improve quality of life.

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COVID Vax Myocarditis Stays Mild With Good Prognosis Over a Year Later

Med Page Today

(MedPage Today) -- People with postvaccine myocarditis did not share the typical mid-term complications associated with conventional myocarditis, based on a population-based study from France. With 18-month follow-up of people who had been hospitalized.

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Prefilled Pens, Fewer Injections Improve Satisfaction in Psoriasis Patients with Needle Phobia

HCPLive

Prefilled pens and fewer injections improve satisfaction in psoriasis patients with needle phobia, enhancing adherence and treatment effectiveness, a study finds.

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Five Things Every Middle Aged Adult Should Know About Sleep & Heart Disease.

Dr. Paddy Barrett

Most people do not know that sleep is a key factor when it comes to good cardiovascular health. Because of this, sleep is pushed to the bottom of the list of priorities for addressing cardiovascular health. In my view, this is a terrible idea. Here is why. Get Sleep Right. Get Everything Else Right. There is a multitude of factors that will determine your cardiovascular risk.

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Catching up on sleep on weekends may lower heart disease risk by up to 20%

Science Daily - Heart Disease

Modern lifestyles mean many people are sleep deprived on work or school days, and try to 'catch-up' with compensatory sleep on weekends. A new study of more than 90,000 individuals showed that those who had the most catch-up sleep on weekends had a 20% lower risk of developing heart disease than those with the least.

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Marked Cognitive Decline in Husbands After a Spouse's CVD Event?

Med Page Today

(MedPage Today) -- Incident cardiovascular disease (CVD) in one spouse was followed by the other developing dementia more often than expected in a large Japanese cohort study. In the study's predominantly male cohort of seniors, the dementia diagnosis.

Dementia 108
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Epigastric and Right Upper Quadrant pain after eating spicy food

Dr. Smith's ECG Blog

A 60-something woman with no cardiac history presented with epigastric and right upper quadrant pain after eating spicy food. She had an ECG recorded at triage: What do you think? This was sent to me without any info while I was out and about, and I looked at it on my phone. I responded: "That is a tough one. V2 is very worrisome. But no other leads are.

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Clinical Measures Insufficient for Capturing Full Patient Experience for Psoriasis

HCPLive

These data suggest that there are a subset of individuals with complete skin clearance of their psoriasis who report residual effects of their condition.

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20 hospitals with the lowest, highest heart attack death rates

Becker's Hospital Review - Cardiology

Discover the top hospitals with the lowest and highest death rates for heart attack patients, according to CMS data.

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Amyloidosis Drug Improves Outcomes, Survival

Med Page Today

(MedPage Today) -- LONDON -- Vutrisiran (Amvuttra) improved functional and disease outcomes as well as survival in transthyretin amyloidosis cardiomyopathy (ATTR-CM), according to findings from the HELIOS-B phase III trial. And the benefits.

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Knowing you have a brain aneurysm may raise anxiety risk, other mental health conditions

American Heart News - Heart News

Research Highlights: People diagnosed with unruptured cerebral aneurysms (weakened areas in brain blood vessels) who are being monitored without treatment have a higher risk of developing mental illness compared to those who have not been diagnosed.

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Trauma History Linked to Reduced Access to Liver Transplant in Women

HCPLive

A study found that women with trauma history have reduced liver transplant access compared to men, with gender disparities not driven by psychiatric symptoms.

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Becoming a patient: a daily exercise in accepting reality

Heart Sisters

Learning to accept reality may often seem counter-intuitive, but could accepting reality be the strategy that can protect against the more dangerous response of DENIAL?

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Stopping Beta-Blockers Did Not Go as Planned for Long-Time Users

Med Page Today

(MedPage Today) -- LONDON -- Heart attack survivors who were expected to be fine after going off their beta-blockers fared worse clinically compared with those who continued them, a randomized trial showed. After years of taking these relatively.

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Prehospital Pulse-Dose Glucocorticoid in STEMI

JAMA Cardiology

This randomized clinical trial investigates if prehospital pulse-dose glucocorticoid treatment has a cardioprotective effect in patients with ST-segment elevation myocardial infarction (STEMI).

STEMI 86
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Perioperative Mortality Risk After Living Kidney Donation Significantly Declined in 2013-2022

HCPLive

Findings from a recent national registry study suggest perioperative mortality after living kidney donation significantly declined in 2013-2022 compared with 1993-2002 and 2003-2012.

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Borderzone Breakthrough: A new source of cardiac inflammation

Science Daily - Heart Disease

Researchers report the discovery of a novel mechanism of cardiac inflammation that may expand therapeutic opportunities to prevent heart attacks from becoming heart failure.

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FDA Clears First Automated Insulin-Delivery Tech for Type 2 Diabetes

Med Page Today

(MedPage Today) -- The FDA cleared the first automated insulin dosing device for adults with type 2 diabetes, the agency announced on Monday. An interoperable automated glycemic controller, Insulet's SmartAdjust technology is software that automatically.

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Gestational diabetes mellitus and development of intergenerational overall and subtypes of cardiovascular diseases: a systematic review and meta-analysis

Cardiovascular Diabetology

Objective We aimed to summarize the association between gestational diabetes mellitus (GDM) and its intergenerational cardiovascular diseases (CVDs) impacts in both mothers and offspring post-delivery in existing literature. Methods PubMed, Embase, Web of Science, and Scopus were utilized for searching publications between January 1980 and June 2024, with data extraction and meta-analysis continuing until 31 July 2024.

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The Clinical Challenge of Seronegative Villous Atrophy: A Preview

HCPLive

Findings suggest a heterogeneous makeup of seronegative enteropathies, presenting difficulty in diagnosing patients with villous atrophy and negative celiac serologic testing.

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Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia

Circulation

Circulation, Volume 150, Issue 9 , Page 724-735, August 27, 2024. Familial hypercholesterolemia (FH) is a genetic disease that leads to elevated low-density lipoprotein cholesterol levels and risk of coronary heart disease. Current therapeutic options for FH remain relatively limited and only partially effective in both lowering low-density lipoprotein cholesterol and modifying coronary heart disease risk.

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Novel insight into neurofilament light chain and rhythm outcomes after catheter ablation of new onset atrial fibrillation:A prospective cohort study

HeartRhythm

Atrial fibrillation (AF) is an age-related disorder closely linked to autonomic nervous system dysfunction. Neurofilament light chain (NFL) protein is a biomarker for neurodegenerative diseases.

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Pathophysiological insights into HFpEF from studies of human cardiac tissue

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 28 August 2024; doi:10.1038/s41569-024-01067-1 The pathophysiology of heart failure with preserved ejection fraction (HFpEF) remains poorly understood. In this Review, Redfield and colleagues highlight the importance of studying human cardiac tissue in HFpEF, discuss sources, challenges and methods for studying human myocardial samples, summarize pathophysiological insights derived from studies of human myocardium in HFpEF and outline knowledge gaps t

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Anemia Increases Cardiac Arrest, Stroke Risk in COVID-19 Admissions

HCPLive

Moderate to severe anemia was linked to an increase in cardiac arrest or stroke compared with normal hemoglobin levels in critically ill COVID-19 patients.

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Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women

The New England Journal of Medicine

Measurement of low-density lipoprotein cholesterol, high-sensitivity C-reactive protein, and lipoprotein(a) predicted the 30-year cardiovascular disease risk among women enrolled in the Women’s Health Study.

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New procedure puts Lee Health on cutting edge of cardiac care

Becker's Hospital Review - Cardiology

Fort Myers, Fla.-based Lee Health completed its first fully endoscopic heart-valve surgery through the smallest incision possible — putting it on the forefront of cardiac care, it said in an Aug. 29 news release.

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Amino Acids May Protect Kidneys During Surgery; EDTA for Chelation Therapy

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Study Compares Accuracy of ChatGPT-3.5, GPT-4 in Diagnosing for Skin of Color

HCPLive

This analysis was designed to examine ChatGPT’s accuracy in diagnosing dermatologic conditions among those with and without skin of color.

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Prevention of Cardiovascular Disease — Don’t Stop Thinking about Tomorrow

The New England Journal of Medicine

Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease.1 Moreover, emerging therapeutic targets include vascular.

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More people at risk of hereditary heart disease than thought

Science Daily - Heart Disease

A new study used data from the UK Biobank to analyze the genes of 469,789 people in the UK and found that one in 1,000 possessed genetic variants with a likely link to cardiac transthyretin (ATTR) amyloidosis.