Circulation

APRIL 17, 2025

Circulation, Ahead of Print. Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements. Although people are living longer lives, there may be an adverse impact on quality of life, necessitating a greater need for palliative care services and support. Palliative care for adults with advanced cardiovascular disease has the potential to significantly improve quality of life for individuals living with cardiovascular disease and their

Cardiovascular Disease 81

Cardiovascular Disease Quality of Life Circulation Research 81

DAIC

APRIL 15, 2025

tim.hodson Tue, 04/15/2025 - 15:54 April 15, 2025 DESKirecently announced FDA clearance for HeartFocus , its AI-enabled heart exam software that empowers any healthcare professional, including novices, to perform clinical-quality heart scans from any compatible device after just a few hours of training. The FDA also approved DESKis Predetermined Change Control Plan (PCCP) for HeartFocus growth opportunities.

Technology 81

Technology Echocardiogram Heart Disease Ultrasound 81

Journal of the American Heart Association

APRIL 17, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundNonvitamin K oral anticoagulants prevent stroke and systemic embolism in patients with nonvalvular atrial fibrillation. However, potential drug interactions with concomitant medications may compromise their efficacy and escalate the risk of adverse effects.Methods and ResultsWe conducted a territorywide retrospective cohort study in Hong Kong, focusing on nonvalvular atrial fibrillation prescribed nonvitamin K oral anticoagulan

Atrial Fibrillation 75

Atrial Fibrillation Hemorrhage Embolism Hospital 75

CardiacWire

APRIL 18, 2025

Building stronger evidence for AIs place in cardiology, this week brought several examples of how AI can improve ECG use cases and automate Echo for new disease detection methods. Starting with AI improving ECG for coronary revascularization , a deep learning ECG model outperformed both clinician-led ECG and troponin T testing in predicting which ED patients needed coronary revascularization.

Tricuspid 59

Tricuspid Research 59

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

Nature Reviews - Cardiology

APRIL 13, 2025

Nature Reviews Cardiology, Published online: 14 April 2025; doi:10.1038/s41569-025-01150-1 In this Review, Liu, Yang and He explore the diverse mechanisms by which various post-translational protein acylations, and the dynamic interactions between them, contribute to cardiac hypertrophy. The authors also discuss the therapeutic potential of targeting acylations to modulate their effects on chromatin architecture, enzyme activity and metabolic pathways.

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DAIC

APRIL 16, 2025

Cedars-Sinai investigators are using AI to analyze images from a common heart test to identify signs of valve disease. Photo: Getty. tim.hodson Wed, 04/16/2025 - 14:19 April 16, 2025 An artificial intelligence (AI) program trained to review images from a common medical test can detect early signs of tricuspid heart valve disease and may help doctors diagnose and treat patients sooner, according to research from the Smidt Heart Institute at Cedars-Sinai.

Heart Valves 71

Heart Valves Tricuspid Echocardiogram Research 71

CardiacWire

APRIL 16, 2025

Completing its pharma comeback story, Verve Therapeutics announced successful results from the Heart-2 Phase 1b Clinical Trial of its in-vivo base editing drug, VERVE-102, that targets the PCSK9 gene for reducing LDL-C. PCSK9 is a molecule that breaks down LDL receptors, so drugs that inhibit it force the bodys LDL receptors to work harder, which reduces LDL-C more efficiently.

Technology 59

Technology Research 59

Stroke Journal

APRIL 18, 2025

Stroke, Ahead of Print. BACKGROUND:Stroke often results in significant impairments across various domains, including movement, language, cognition, and mood. Neurostimulants have been proposed as potential therapeutic interventions to enhance recovery in these areas.METHODS:This narrative literature review examines clinical trials investigating the efficacy of neurostimulants in poststroke recovery.

Stroke 53

Stroke Strokes Outcomes 53

Cardiometabolic Health Congress

APRIL 18, 2025

World Liver Day 2025 | A Global Call to Action for Liver Health through Nutrition A global coalition of leading health organizations unites to mark World Liver Day on Saturday, April 19, emphasizing the pivotal role of nutrition in supporting liver function and preventing disease. With the theme Food is Medicine, the campaign urges the global community to take action through sustainable lifestyle changes.

Diet 52

Diet CME Exercise Education 52

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

Cardiovascular disease (CVD) remains a global health burden despite advances in prevention and treatment. Conventional biomarkers, while effective for a number of patient groups, fail to provide personalized diagnosis and prognosis, necessitating the exploration of novel markers. Advancements in sequencing technology have unveiled the role of cell-free DNA (cfDNA) as a reservoir of genetic information from all cells within the body, and associations between elevated cfDNA levels and CVD risk fac

Cardiovascular Disease 52

Cardiovascular Disease Circulation Biomarkers Risk Factors 52

Med Page Today

APRIL 14, 2025

(MedPage Today) -- People that required emergency department (ED) or acute hospital care for cannabis use may have an increased risk of a subsequent dementia diagnosis, a retrospective matched cohort study of 6 million people in Canada suggested.

Dementia 132

Dementia Hospital 132

American Heart News - Heart News

APRIL 17, 2025

Research Highlights: Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk.

Risk Factors 126

Risk Factors Stroke Strokes Research 126

HCPLive

APRIL 16, 2025

Experts discuss the challenges of identifying and diagnosing hypercortisolism, the reasons behind its often-delayed diagnosis, the impact of a wide spectrum of clinical signs and symptoms on clinicians ability to diagnose the condition, and recent data on the prevalence of hypercortisolism in at-risk populations, including those with difficult-to-control diabetes, hypertension, and cardiovascular disease.

Cardiovascular Disease 52

Cardiovascular Disease Diabetes Hypertension 52

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

Chronic heart failure (CHF) combined with depression represents a significant clinical challenge due to the mutual exacerbation of physical and psychological symptoms. This study investigated the therapeutic effects of Zhigancao decoction, a traditional Chinese medicine, in combination with conventional Western treatments in patients with CHF and depression.

Heart Failure 52

Heart Failure Quality of Life Cardiac Function Outcomes 52

Med Page Today

APRIL 17, 2025

(MedPage Today) -- Hearing loss may play a bigger role in dementia than previously thought, data from a U.S. cohort study suggested. In a sample of nearly 3,000 older adults, up to 32% (95% CI 11.0%-46.5%) of incident dementia over 8 years could.

Dementia 124

Dementia 124

Stroke Journal

APRIL 17, 2025

Stroke, Ahead of Print. BACKGROUND:Branch atherosclerosis disease (BAD) is prone to early neurological deterioration (END). The purpose of this study was to assess the efficacy and safety of argatroban plus dual antiplatelet therapy (DAPT) for preventing END in high-risk branch atherosclerosis disease patients.METHODS:This multicenter, open-label, blinded end point, randomized controlled trial including branch atherosclerosis disease patients with mild stroke (National Institutes of Health Strok

Atherosclerosis 45

Atherosclerosis Stroke Strokes Hemorrhage 45

American Heart News - Heart News

APRIL 14, 2025

Statement Highlights: While the strongest evidence exists that getting sufficient sleep (duration of sleep) is important for overall health , other components of sleep health, such as consistent bedtime, uninterrupted sleep, daytime functioning and.

Cardiovascular Disease 118

Cardiovascular Disease 118

Frontiers in Cardiovascular Medicine

APRIL 14, 2025

BackgroundHeart failure (HF) is a multifaceted clinical condition, and our comprehension of its genetic pathogenesis continues to be significantly limited. Consequently, identifying specific genes for HF at the transcriptomic level may enhance early detection and allow for more targeted therapies for these individuals.MethodsHF datasets were acquired from the Gene Expression Omnibus (GEO) database (GSE57338), and through the application of bioinformatics and machine-learning algorithms.

Heart Failure 52

Heart Failure Cancer Research 52

HCPLive

APRIL 18, 2025

Dupilumab's approval marks the first new, targeted therapy for CSU in more than a decade and is the 7th indication for a disease with underlying type 2 inflammation.

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Med Page Today

APRIL 18, 2025

(MedPage Today) -- The Supreme Court will hear oral arguments Monday in a case that could affect what kind of preventive care is covered at no charge under Americans' health insurance plans. The case, known as Kennedy v. Braidwood, involves Christian.

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Science Daily - Heart Disease

APRIL 14, 2025

New research suggests increasing the ratio of dietary potassium to sodium intake may be more effective for lowering blood pressure than simply reducing sodium intake.

Blood Pressure 112

Blood Pressure Research 112

Frontiers in Cardiovascular Medicine

APRIL 16, 2025

Background and AimHypertension (HTN) is a widespread global health challenge, and its increasing prevalence is attributed to individual and environmental risk factors. Persistent organic pollutants (POPs), especially polychlorinated biphenyls (PCBs), contribute to cardiovascular risk by accumulating in fatty tissues, which leads to oxidative stress and vascular inflammation.

Hypertension 52

Hypertension Risk Factors Research 52

Dr. Prateek Bhatnagar

APRIL 13, 2025

Dr. Prateek Bhatnagar, the best cardiac surgeon in India, operated a 68-year-old gentleman from Bengal, who had been refused coronary bypass surgery by leading cardiac centers across India, due to the high-risk nature of his condition. The patient had a critically low pumping of heart (left ventricular ejection fraction) of just 22%, indicating severely compromised heart function.

Bicuspid/Mitral 52

Bicuspid/Mitral Hospital 52

HCPLive

APRIL 18, 2025

Greenspan offers tips in treating seasonal allergies in patients with pulmonary conditions, such as long-COVID, and provides his 2025 spring allergy prediction.

Pulmonary 104

Pulmonary 104

Science Daily - Heart Disease

APRIL 14, 2025

Healthy sleep includes multiple components, such as number of hours of sleep per night, how long it takes to fall asleep, daytime functioning and self-reported sleep satisfaction, and addressing these different dimensions of sleep may help to reduce cardiometabolic health and related risk factors, according to a new scientific statement.

Cardiovascular Disease 108

Cardiovascular Disease Risk Factors 108

Frontiers in Cardiovascular Medicine

APRIL 16, 2025

BackgroundLeft ventricular hypertrophy (LVH) is often a complication of hypertension and an independent risk factor for cardiovascular events. In Ethiopia, there is a scarcity of data on the prevalence and associated factors of left ventricular hypertrophy among hypertensive adults. This study aimed to assess the prevalence and associated factors of left ventricular hypertrophy among adult patients with hypertension attending treatment at two public hospitals in Harar, Eastern Ethiopia from 20 D

Hypertension 52

Hypertension Blood Pressure Risk Factors Hospital 52

Med Page Today

APRIL 12, 2025

(MedPage Today) -- BOSTON -- After living kidney donation, projection of renal function may vary by gender, a retrospective cohort study of 174,311 living kidney donors suggested. Over a median 6.7 months, the incidence rate of worsening post.

Outcomes 104

Outcomes 104

Journal of Cardiovascular Electrophysiology

APRIL 16, 2025

ABSTRACT Introduction Pulsed Field Cryoablation (PFCA) is a dual-energy cardiac ablation modality consisting of short-duration ultra-low temperature cryoablation (ULTC) followed immediately by pulsed field ablation (PFA) delivered from the same catheter. It is hypothesized that PFCA may improve contact stability during PFA, while maintaining lesion depth and effectiveness of ULTC.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Pulmonary Hospital 40

Heart Sisters

APRIL 13, 2025

I was told I’d hear the pathology lab results after my breast biopsy as soon as they were available. But the results sure weren’t what I expected.

Heart Disease 100

Heart Disease Cancer 100

Frontiers in Cardiovascular Medicine

APRIL 15, 2025

ObjectiveThe aim of this study was to examine the effectiveness of brief aerobic exercise on patients diagnosed with hyperlipidemia.MethodsSeventy patients diagnosed with hyperlipidemia were enrolled from community health centers between May 2023 and October 2023. They were randomly assigned into two groups: test and control group, each consisting of 35 patients.

Exercise 52

Exercise Blood Pressure Research 52

HCPLive

APRIL 18, 2025

This interview in the latest issue of The Respiratory Report features Divay Chandra, MD, MSc, discussing lithium's potential enhancement of alveolar repair after injury.

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Journal of Cardiovascular Electrophysiology

APRIL 16, 2025

ABSTRACT Introduction The role of corticosteroids in the management of ventricular tachyarrhythmia (VA) in cardiac sarcoidosis (CS) remains controversial. This study assessed the effect of early steroid initiation on VA recurrence rates in patients with CS and evaluated VA frequency before and after steroid therapy. Methods From a registry of 137 patients with CS with arrhythmias, those with VA and more than 60 days of follow-up were included.

Arrhythmia 40

Arrhythmia Article 40

Stroke Journal

APRIL 18, 2025

Stroke, Ahead of Print. BACKGROUND:The international trial AVERT (A Very Early Rehabilitation Trial) found that very early mobilization (VEM; commenced <24 hours after stroke) negatively affected functional outcome (modified Rankin Scale [mRS]). The drivers of this effect remain unclear. One plausible mechanism is that high-dose upright activity worsens cerebral perfusion in patients with cerebral large vessel occlusion (LVO).

Stroke 40

Stroke Strokes Thrombolysis Outcomes 40

Frontiers in Cardiovascular Medicine

APRIL 15, 2025

Severe tricuspid regurgitation (TR) is a prevalent and challenging condition associated with poor survival outcomes and significant morbidity. Medical therapy alone often fails to provide adequate symptom relief, and stand-alone surgical intervention is linked to high mortality rates, making it a less favorable option unless combined with left-sided valve surgery.

Tricuspid 52

Tricuspid Outcomes 52

HCPLive

APRIL 16, 2025

Ustekinumab and its generic biofamailiar SYSA1902 exhibited clinical equivalence in terms of safety, efficacy, pharmacokinetics, and immunogenicity.

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Plaque 95

Medical Xpress - Cardiology

APRIL 14, 2025

Researchers from Rutgers Health and RWJBarnabas Health have developed an artificial intelligence (AI) technology that transforms basic electrocardiogram (ECG) readings of electrical activity into sophisticated heart motion signals normally obtained via echocardiogram, potentially improving how heart disease is detected and monitored.

Echocardiogram 91

Echocardiogram Electrocardiogram Technology Heart Disease 91