Sat.Nov 02, 2024 - Fri.Nov 08, 2024

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Midlife Choices May Offset Genetic Risk for Dementia, Stroke, Late-Life Depression

Med Page Today

(MedPage Today) -- Healthier lifestyle behaviors in midlife were linked with better outcomes in people with genetic predisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed. Over about 12 years of follow-up.

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Should You Take A Statin To Lower Your Cholesterol?

Dr. Paddy Barrett

Let’s start with the fact that this is not a yes or no answer. To answer this question, you need to understand three key factors: What is your baseline risk? Over what time horizon are you looking to reduce risk? What is your attitude toward reducing that risk? Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol.

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Role of Testing in CSU Diagnosis

HCPLive

Panelists discuss the recommended diagnostic testing for chronic spontaneous urticaria (CSU), noting that extensive testing is not necessary and that routine blood counts, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), IgG anti-thyroid peroxidase (TPO), and total IgE are adequate, while also addressing the limited role of biopsy; they further explore how disease severity is assessed using tools like Urticaria Activity Score (UAS7) and Urticaria Control Test (UCT).

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Epigenomic biomarkers of cardiometabolic disease: How far are we from daily practice?

Cardiovascular Diabetology

Determining whether someone has cardiometabolic disease (CMD), especially in the early stages, can be complicated. Risk stratification ordinarily depends on an extended process relying on medical history that.

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FDA Adds New Warning to GLP-1 Drugs

Med Page Today

(MedPage Today) -- Labels of all GLP-1 receptor agonists now carry a warning about pulmonary aspiration during general anesthesia or deep sedation. The warning affects all treatments containing GLP-1 receptor agonists, including semaglutide (Ozempic.

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Boston Scientific Bolsters AFib Mapping with Cortex Acquisition

CardiacWire

Boston Scientific made what could become a major addition to its electrophysiology portfolio, acquiring AFib mapping startup Cortex, Inc. for an undisclosed sum. Cortex gives Boston Scientific a new mapping technology that detects AFib signs and triggers outside of the pulmonary veins, and can help EP teams develop ablation strategies for more complex AFib cases.

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Risankizumab Effectively Clears Psoriasis in Indirect Comparison to Deucravacitinib

HCPLive

Risankizumab achieves significantly higher rates of skin clearance and improved quality of life versus deucravacitinib in matching-adjusted indirect comparison analysis.

More Trending

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Alzheimer's Progression May Be Slowed by Targeted Magnetic Pulses, Study Suggests

Med Page Today

(MedPage Today) -- Investigational transcranial magnetic stimulation that targeted a brain network involved in memory slowed progression in mild-to-moderate Alzheimer's disease, data from a small phase II study suggested. At 1 year, noninvasive.

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Five minutes of extra exercise a day could lower blood pressure

Science Daily - Heart Disease

New research suggests that adding a small amount of physical activity -- such as uphill walking or stair-climbing -- into your day may help to lower blood pressure.

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Dupilumab Reduces Itch in Chronic Spontaneous Urticaria in Phase 3 Data

HCPLive

According to Phase 3 LIBERTY-CUPID trial results, dupilumab significantly reduces itch and hive activity from baseline in chronic spontaneous urticaria.

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What's overweight enough for lower disability after stroke?

Science Daily - Stroke

Slightly overweight stroke survivors have a lower risk of sustaining disabilities. New research adds another aspect to the obesity paradox but also highlights the importance of considering the population's normal when recommending best practices.

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Patients With Obesity Shed Pounds With Drug-Free Capsule

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Use of an oral biodegradable drug-free capsule led to more weight loss among patients with overweight or obesity compared with placebo, according to the randomized RESET trial. Among 279 patients, mean change.

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Dog-owner interaction is reflected in heart rate variability

Science Daily - Heart Disease

A recent study showed that the heart rate variability of a dog and its owner adapt to each other during interaction. High heart rate variability is associated with relaxation, while low heart rate variability indicates stimulation. The study deepens our understanding of the emotional connection between a dog and its owner, including its underlying physiological mechanisms.

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Phase 3 Data Shows TEV-‘749 Injection Improves Social Function in Schizophrenia

HCPLive

Teva presents 2 findings at Psych Congress 2024: TEV’749’s effects on social function and quality of life in adults with schizophrenia and risperidone adherence patterns.

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Top-ranked hospitals for pacemaker placement, by state

Becker's Hospital Review - Cardiology

California and Florida have the most top-ranked hospitals for pacemaker or defibrillator placement in the U. S. , according to the WebMD Choice Awards.

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Early-Life Sugar Restriction Reduced Diabetes, Hypertension Risk

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Limiting exposure to sugar starting in utero reduced risk and delayed onset of type 2 diabetes and hypertension in adulthood, a study showed. Adults exposed to early-life sugar rationing in the U.K. for at least.

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A little more on the trial

Dr. Malcolm Kendrick

When the background information leading up to the libel trial was released to us, there was one trail of e-mails that struck me as very damning. It emerged that Barney Calman was very keen to find case histories where people had stopped taking statins and then suffered a catastrophic event, such as a heart attack or stroke, or dying. This ‘ stopping statins and dying’ concept was pretty much central to the articles.

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Autoimmune/Inflammatory Tissue Disorders Associated With COVID-19 Infection

HCPLive

A new cohort study including over 6 million participants has found an increased likelihood of Behçet disease, alocpecia, bulbous pemphigoid and other disorders post-COVID infection.

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Advanced heart model can provide patient-specific simulations

Medical Xpress - Cardiology

A team led by researchers at UNC-Chapel Hill have developed an innovative computer model of blood flow in the human heart that promises to transform how we understand, diagnose, and treat heart conditions. This new model, grounded in realistic mathematical descriptions of the heart's anatomy and physiology, successfully captures normal heart function and can predict how the heart responds to different levels of blood flow.

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Nurse's Death Tied to GLP-1 Drug; Research Monkey Jailbreak; Congressman Has Cancer

Med Page Today

(MedPage Today) -- Note that some links may require registration or subscription. Diabetes and weight-loss drug tirzepatide (Mounjaro, Zepbound) was listed as a contributing factor in the death of a 58-year-old nurse from Scotland who died of.

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Defibrillation devices can save lives using 1,000 times less electricity

Science Daily - Heart Disease

Researchers used an electrophysiological computer model of the heart's electrical circuits to examine the effect of the applied voltage field in multiple fibrillation-defibrillation scenarios. They discovered far less energy is needed than is currently used in state-of-the-art defibrillation techniques. The authors applied an adjoint optimization method and discovered adjusting the duration and the smooth variation in time of the voltage supplied by defibrillation devices is a more efficient mec

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Monica Kraft, MD: Discussing Phase 3b Findings on Albuterol/Budesonide for Asthma

HCPLive

This interview with Kraft features a discussion regarding her team’s new data from the BATURA study on albuterol for patients’ asthma exacerbations.

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An extra five minutes of exercise per day could help to lower blood pressure

Medical Xpress - Cardiology

Adding small amounts of exercise into daily routine, such as climbing stairs or cycling errands, could help to reduce blood pressure, with just five additional minutes a day estimated to yield improvements, finds a new study from researchers at UCL and the University of Sydney.

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Zepbound's Weight Loss, Cardiometabolic Benefits Hold Up at 3 Years

Med Page Today

(MedPage Today) -- SAN ANTONIO -- Patients with overweight or obesity lost an average one-fifth of their body weight with the highest dose of tirzepatide (Zepbound) and maintained that loss for more than 3 years, follow-up of a randomized trial.

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Using a fan and wetting the skin reduces risk of deadly cardiac strain in hot and humid weather

Science Daily - Heart Disease

New collaborative research has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US. The study looked at the efficacy of different low-cost cooling strategies -- such as electric fans with and without spraying water on the skin -- for older adults, who are known to be at a heightened health risk during hot summer weather.

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Survey Highlights Critical Role of Pharmacists in HCV Management

HCPLive

Survey data show pharmacists are integral to HCV screening and treatment across healthcare settings, highlighting their contributions to HCV elimination efforts.

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New findings on heart failure: Dysferlin protein protects and shapes the membrane of heart muscle cells

Medical Xpress - Cardiology

Researchers from the Heart Center of the University Medical Center Göttingen (UMG) led by Priv.-Doz. Dr. Sören Brandenburg have identified a protein that plays a central role in the heart's adaptation to increased stress. The results of the study were published in Circulation Research.

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Mixed Bag for Clinicians Vying for House Seats

Med Page Today

(MedPage Today) -- The presidential election was not the only race on Tuesday -- the seats for all 435 members of the House were also up for grabs. See below how some of the healthcare-affiliated non-incumbent candidates fared, according to results.

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Baseline wander. But what else do you see?

Dr. Smith's ECG Blog

Written by Magnus Nossen The below ECG was obtained from a 65 year old man with ongoing chest pain. He has a history of hypertension an d tobacco use. He is otherwise healthy. There is no prior ECG for comparison. What do you think? ECG #1 Interpretation: The quality of the above ECG is not optimal. There is significant baseline wander that does make it more challenging to interpret ischemic changes.

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Current Interventions Fail to Reduce Benzodiazepine Use in Older Adults

HCPLive

Neither clinician peer comparison nor patient informational mail reduced benzodiazepine use among older adults in anesthesia care, a new study finds.

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Lesbian, gay, bisexual veterans at greater risk for cardiovascular disease even when accounting for inequities

Medical Xpress - Cardiology

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death among U.S. adults. Despite declining rates of ASCVD mortality, significant disparities across multiple social and demographic characteristics, such as race and income, persist.

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Examining the clinical role and educational preparation of heart failure nurses across Europe. A survey of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) and the Association of Cardiovascular Nursing and Allied Professions (ACNAP) of the ESC

European Journal of Heart Failure

The clinical role and educational preparation of heart failure nurses across Europe. HF, heart failure; HFN, heart failure nurse; MDT, multidisciplinary team. Aims To describe the clinical practice and educational preparation of heart failure (HF) nurses across Europe and determine the key differences between countries. Methods and results A survey tool was developed, in English, by the Heart Failure Association Patient Care committee of the European Society of Cardiology (ESC).

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Superior Vena Cava Isolation After Pulsed-Field Ablation of the Right Superior Pulmonary Vein

HeartRhythm

Superior vena cava (SVC) conduction delay or isolation during right superior pulmonary vein (RSPV) ablation using thermal ablation technologies has been previously described.1,2 No reports regarding the impact of pulsed-field ablation (PFA) on the SVC exist.

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Racial, Ethnic IgA Nephropathy Stratification Provides New Insight Into US Incidence

HCPLive

The study is one of the first to report United States IgAN incidence based on a large racially and ethnically diverse cohort.

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Can a mammogram identify heart disease risk?

Medical Xpress - Cardiology

When people check in for their annual mammogram these days, some may face a surprising question: In addition to reviewing the mammogram for breast cancer, would the patient like the radiologist to examine the images for heart disease risk?

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Antithrombotic Therapy in High Bleeding Risk for Noncardiac Interventions: Key Points

American College of Cardiology

The following are key points to remember from a state-of-the art review on antithrombotic therapy in patients with high bleeding risk (HBR) noncardiac percutaneous interventions from the Working Group of Thrombosis of the Italian Society of Cardiology.

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Physiology Friday #243: Brief Activity Bouts Throughout the Day Make Sedentary Behavior Less Risky

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post! Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. “Sitting is the new smoking” is a metaphor that I once found to be hyperbolic.