Medical Xpress - Cardiology

MARCH 7, 2025

Researchers report a discovery in cardiac regeneration that offers new hope for the treatment of ischemic heart failure. Published in npj Regenerative Medicine, the study reveals a novel approach to promoting cardiomyocyte proliferation. The researchers are from the Michael E. DeBakey Department of Surgery at Baylor College of Medicine, the QIMR Berghofer Medical Research Institute in Brisbane, Australia, and collaborating institutions.

Heart Failure 138

Heart Failure Research 138

The British Journal of Cardiology

MARCH 4, 2025

Coronary artery spasm (CAS), or Prinzmetal angina, is a recognised cause of myocardial ischaemia in non-obstructed coronary arteries which typically presents with anginal chest pain. This case report describes an atypical presentation of CAS in a 68-year-old white British male with cardiovascular risk factors. The patient presented with recurrent palpitations and pre-syncope, with no chest pain.

Chest Pain 73

Chest Pain Tachycardia Angina Arrhythmia 73

Nature Reviews - Cardiology

MARCH 2, 2025

Nature Reviews Cardiology, Published online: 03 March 2025; doi:10.1038/s41569-025-01140-3 The brainheart axis comprises the anatomical and functional interaction between the neural and cardiovascular systems that regulate physiological, cognitive and emotional states in both health and disease. In this Review, Valenza and colleagues explore the three primary pathways of the brainheart axis neural, mechanical and biochemical discussing the regulatory mechanisms generated by each individual pat

Physiology 64

Physiology 64

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

BackgroundHeart failure (HF), a global health challenge, is a leading cause of mortality in hospitalized patients. Early and accurate prognostic evaluation in these patients is vital for guiding clinical management. Our aim was to explore the association between albumin-corrected calcium (ACC) and mortality in hospitalized patients.MethodsThis retrospective cohort study utilized data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database.

Heart Failure 52

Heart Failure Hospital Outcomes Research 52

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AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

Medical Xpress - Cardiology

MARCH 7, 2025

Teenagers who do not get the recommended amount of sleep may be at an increased risk for high blood pressure, according to preliminary research presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Scientific Sessions 2025. The meeting is being held in New Orleans, March 69, 2025, and features the latest science on population-based health and wellness and implications for lifestyle.

Blood Pressure 80

Blood Pressure Research 80

Journal of Clinical Investigation - Cardiology

MARCH 3, 2025

N-methyl-d-aspartate (NMDA) receptormediated autoimmune encephalitis (NMDAR-AE) is the most common cause of autoimmune encephalitis, especially in children and young adults. The disorder is caused by antibodies directed against the GluN1 protein, an obligatory constituent of NMDA receptors, which are key signaling molecules in brain development, learning and memory, and executive function.

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Frontiers in Cardiovascular Medicine

MARCH 5, 2025

IntroductionHeart failure (HF) with improved ejection fraction (HFimpEF) was shown to be related with improved outcome but increase of left ventricular ejection fraction (LVEF) in patients without HF is of less known clinical significance. The aim of the study was to evaluate long-term prognosis in patients with different cardiovascular disorders, with and without HF, depending on temporal variations of LVEF.MethodsThe study covered 31 920 patients (median age 71 years, 37.7% females) with diffe

Heart Failure 52

Heart Failure Outcomes Academic Research 52

Med Page Today

MARCH 7, 2025

(MedPage Today) -- Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) was tied to a decreased risk of dementia, data from the prospective Rotterdam Study showed. Over an average follow-up of 14.5 years, use of NSAIDs for 24 months.

Dementia 125

Dementia 125

Journal of Clinical Investigation - Cardiology

MARCH 3, 2025

Cellular senescence is a cell state induced by irreparable cellular damage. The hallmark of senescence is cell cycle exit, yet neurons, which are postmitotic from birth, have also been found to undergo senescence. Neuronal senescence is prevalent in aging as well as in neurodegenerative disease. However, a role for senescence in epilepsy is virtually unexplored.

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HCPLive

MARCH 1, 2025

There was a 79% relative reduction in annualized asthma exacerbation rate in the 6 months after starting treatment compared with the prior 6 months.

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Frontiers in Cardiovascular Medicine

MARCH 6, 2025

BackgroundIn the electrophysiologic (EP) lab, technical support for implantable cardioverter/defibrillators (ICD) and cardiac resynchronization therapy (CRT-D) procedures is often limited by the availability and costs of field clinical specialist (FCS) bioengineers.MethodsThis study explores the viability of using remote support through an internet-based platform for ICD and CRT-D implantation procedures, aiming to enhance efficiency and overcome geographical or pandemic-related barriers.

Defibrillator 52

Defibrillator Electrophysiology Research 52

American Heart News - Heart News

MARCH 6, 2025

Research Highlights: The prevalence of cardiovascular disease risk factors varies greatly among Asian American, Native Hawaiian and other Pacific Islander (AANHPI) populations, according to an analysis of electronic health records for more than.

Risk Factors 121

Risk Factors Cardiovascular Disease Stroke Strokes 121

The British Journal of Cardiology

MARCH 4, 2025

Acute coronary syndromes (ACS) are common in patients with end-stage renal disease (ESRD). Diagnosis may be challenging given diverse symptomatology, absence of classical symptoms on presentation, and difficulties in the interpretation of biomarkers. Morbidity and mortality in this patient population remain high compared with patients with normal renal function, partly due to a lack of evidence for optimal management.

Biomarkers 49

Biomarkers Article 49

Journal of the American Heart Association

MARCH 7, 2025

Journal of the American Heart Association, Ahead of Print. BackgroundThe Fontan operation is the current standard of care for singleventricle congenital heart disease. Almost all patients with Fontan operation develop liver fibrosis at a young age, known as Fontanassociated liver disease (FALD). The pathogenesis and mechanisms underlying FALD remain little understood, and there are no effective therapies.

Congenital Heart Disease 45

Congenital Heart Disease Congenital Heart Disease Circulation 45

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

IntroductionDual-task training (DTT) emerged as a promising intervention strategy to improve cognition in individuals with cardiovascular diseases (CVDs). The aim of this study is to describe the literature on the relationship between motor-cognitive DTT and cognitive performance (CP) in individuals with coronary artery disease (CAD) and/or heart failure (HF).MethodThis systematic review includes intervention and observational studies that assessed motor-cognitive DTT on CP in individuals with C

Coronary Artery Disease 52

Coronary Artery Disease Heart Failure Cardiac Rehabilitation Article 52

American Heart News - Heart News

MARCH 6, 2025

Research Highlights: Teenagers who slept less than 7.7 hours in a sleep lab were observed to be almost three times more likely to have elevated blood pressure than well-rested peers. Those who reported insomnia and slept less than 7.7 hours in a.

Blood Pressure 115

Blood Pressure Research 115

All About Cardiovascular System and Disorders

MARCH 2, 2025

Calculation of intracardiac shunts by cardiac cath and Flamm formula. Pulmonary blood flow is designated as QP and systemic blood flow as QS in hemodynamic calculations. When there is a left to right shunt, pulmonary blood flow is more than the systemic blood flow. The systemic blood flow is more than the pulmonary blood flow when there is a right to left shunt.

Pulmonary 52

Pulmonary General Cardiology 52

Science Daily - Heart Disease

MARCH 7, 2025

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

Heart Failure 112

Heart Failure Research 112

Frontiers in Cardiovascular Medicine

MARCH 5, 2025

Pulmonary artery sling (PAS) is an uncommon congenital anomaly in which the left pulmonary artery (LPA) originates abnormally from the posterior aspect of the right pulmonary artery (RPA). The LPA then traverses between the trachea and esophagus, resulting in compression of the lower trachea. This compression can lead to respiratory symptoms, including wheezing and stridor, and in some cases, airway obstruction.

Pulmonary 52

Pulmonary Congenital 52

Med Page Today

MARCH 3, 2025

(MedPage Today) -- An investigational compound incorporating an herbal-based supplement improved blood glucose in adults with inadequately controlled type 2 diabetes in a Chinese phase II randomized clinical trial. By week 12, HbA1c significantly.

Diabetes 112

Diabetes 112

The British Journal of Cardiology

MARCH 4, 2025

Pericardial cyst is a rare diagnosis, mainly considered a congenital condition. Most patients with pericardial cysts present without symptoms. Symptomatic presentation often relates to the size and location of the pericardial cyst. We report a case of a 49-year-old man who presented with subacute breathlessness in which the diagnosis of a pericardial cyst was made following various investigations from transthoracic echocardiography and computed tomography scan to video-assisted thoracoscopic su

Congenital 45

Congenital Outcomes Article 45

HCPLive

MARCH 5, 2025

In part 1 of this episode of Crisis Point, 3 nephrology experts and a patient advocate discuss CKDs emergence as a public health crisis.

Kidney Disease 110

Kidney Disease Public Health 110

Frontiers in Cardiovascular Medicine

MARCH 6, 2025

BackgroundCongenital absence of the right coronary artery (RCA) is an extremely rare coronary anomaly with a very low incidence in the general population. The prevalence of complete atrioventricular (AV) block also appears to be low. No previous reports have documented the coexistence of congenital absence of the RCA and complete AV block in the same patient.Case summariesCase 1 was a 52-year-old man with no significant past medical history who experienced syncope.

Congenital 52

Congenital Pacemaker Myocardial Infarction Atherosclerosis 52

JAMA Cardiology

MARCH 4, 2025

This Special Communication discusses the measurement of coronary artery calcium score in those at intermediate risk for atherosclerotic cardiovascular disease, when such testing may be omitted or deferred and when it may provide clinically useful information.

Cardiovascular Disease 108

Cardiovascular Disease 108

Science Daily - Heart Disease

MARCH 7, 2025

The discovery of a novel approach to promote cardiomyocyte proliferation offers new hope for the treatment of ischemic heart failure.

Heart Failure 106

Heart Failure Research 106

Becker's Hospital Review - Cardiology

MARCH 6, 2025

"It's kind of like that quote in "Field of Dreams," 'If you build it, they will come,'" Tom Nguyen, MD, told Becker's of the robotic cardiac surgery program at the Baptist Health Miami Cardiac & Vascular Institute. "It's pretty clear that we built it and they're coming.

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Frontiers in Cardiovascular Medicine

MARCH 6, 2025

BackgroundCoronary heart disease (CHD) is a pervasive chronic condition that poses a significant threat to global health and mortality worldwide. Given the severity of this disease, it is imperative to consider pivotal factors such as age, concurrent diseases, and physical frailty of patients diagnosed with ischemic non-obstructive CHD prior to initiating cardiopulmonary rehabilitation.

Cardiac Function 52

Cardiac Function Exercise Heart Disease Ischemia 52

The British Journal of Cardiology

MARCH 4, 2025

Acute coronary syndrome (ACS) events in people receiving long-term haemodialysis (HD) are common, present atypically and are associated with poor outcomes. 13 Diagnosis is challenging, and treatment even more so. The complexity of this population drives their exclusion from clinical trials, resulting in a scarcity of evidence supporting any optimal treatment strategy. 4 Guidelines are, as a result, vague and, to a degree, contradictory. 57 These are some of the reasons that the combination of ca

Kidney Disease 45

Kidney Disease Outcomes Article 45

Med Page Today

MARCH 3, 2025

(MedPage Today) -- A fuller picture of protein S deficiency emerged with large-scale research showing the immense thrombotic risks faced by carriers of rare loss-of-function gene variants, though patients with non-inherited forms of the condition.

Research 106

Research 106

HCPLive

MARCH 1, 2025

HCPLive spoke with Cohen about how patients with a peanut allergy responded to oral immunotherapy with autoclaved peanuts.

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Frontiers in Cardiovascular Medicine

MARCH 5, 2025

Introduction and objectivesThe use of vitamin K antagonists (VKA) in patients with atrial fibrillation (AF) in Spain remains high, even though the available data on anticoagulation control (TRT, time in therapeutic range) shows suboptimal results. The objective of the AMFA project, an atlas of the management of anticoagulation in patients with AF, was to describe oral anticoagulation management in Spanish patients.Materials and methodsThe AMFA Project is a descriptive, multicenter study.

Atrial Fibrillation 52

Atrial Fibrillation Research 52

Medical Xpress - Cardiology

MARCH 6, 2025

Two studies led by researchers at the Broad Institute of MIT and Harvard and Mass General Brigham have greatly expanded the number of known genetic variants that boost the risk for atrial fibrillation (AF), a common heart condition marked by an irregular heartbeat that can lead to stroke and heart failure.

Atrial Fibrillation 103

Atrial Fibrillation Heart Failure Research Stroke 103

Med Page Today

MARCH 5, 2025

(MedPage Today) -- Most of America "springs forward" Sunday for daylight saving time and losing that hour of sleep can do more than leave you tired and cranky the next day. It also could harm your health. Darker mornings and more evening light.

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HCPLive

MARCH 7, 2025

Chambliss and colleagues found a 1% increase in asthma-related emergency department visits per unit of distance to semiconductor fabrication plants.

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JAMA Cardiology

MARCH 4, 2025

This Viewpoint recommends simultaneous or rapid sequence initiation of combination therapy with 3 specific classes of medication for heart failure with mildly reduced ejection fraction or preserved ejection fraction.

Preserved Ejection Fraction 101

Preserved Ejection Fraction Heart Failure 101

Medical Xpress - Cardiology

MARCH 7, 2025

A study published in The Lancet Regional HealthAmericas highlights a growing divide in cardiovascular health in the U.S., showing that wealth and education play a significant role in heart disease risk.

Education 100

Education Heart Disease 100