HCPLive
DECEMBER 12, 2024
An FDA review of postmarket clinical trial data revealed an increased risk of liver injury with obeticholic acid in patients with PBC without cirrhosis.
Science Daily - Heart Disease
DECEMBER 11, 2024
Scientists have made a significant breakthrough in understanding how 'bad' cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptor -- a process that starts the clearing of LDL from the blood -- and what happens when that process gets impaired.
Medical Xpress - Cardiology
DECEMBER 11, 2024
National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were able to show for the first time how the main structural protein of LDL binds to its receptora process that starts the clearing of LDL from the bloodand what happens when that process gets impaired.
Med Page Today
DECEMBER 13, 2024
(MedPage Today) -- Diets higher in inflammatory foods were tied to an increased incidence of dementia in older adults, longitudinal data from the Framingham Heart Study Offspring cohort showed. Over 13 years of follow-up, higher Dietary Inflammatory.
HCPLive
DECEMBER 10, 2024
Navigating the long road of Long COVID requires more than just recovery from an infection, it demands specialized, multifaceted care to address persistent and often invisible neurological symptoms.
Science Daily - Heart Disease
DECEMBER 11, 2024
Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels.
Medical Xpress - Cardiology
DECEMBER 13, 2024
The devastating news of a cancer diagnosis understandably makes doctors and patients focus on the cancer itself. However, experts in cardio-oncology from the European Society of Cardiology (ESC) emphasize that heart and cardiovascular health must be included as early as possible in the patient's cancer treatment plan to ensure the best possible outcomes.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HCPLive
DECEMBER 12, 2024
Patients with schizophrenia and COVID-19 both present dysregulated energy metabolism, explaining the high COVID-19 rates among those with schizophrenia.
Frontiers in Cardiovascular Medicine
DECEMBER 9, 2024
BackgroundLow-Density Lipoprotein Cholesterol (LDL-C) is the primary lipid therapy target for coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI). However, progression of coronary atherosclerosis occurs even LDL-C controlled well, some potentially important factors have been overlooked.ObjectiveThis study aims to elucidate the relationship between remnant lipoprotein particle cholesterol (RLP-C) and the progression of non-target lesions (NTLs) in patients with w
Medical Xpress - Cardiology
DECEMBER 10, 2024
A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves survival, in what a paper describing the results calls "an unprecedented recovery of cardiac function.
Med Page Today
DECEMBER 12, 2024
(MedPage Today) -- Actor, comedian, and singer Jamie Foxx revealed that his mystery ailment last year was a brain bleed and stroke. In his new comedy special "Jamie Foxx: What Had Happened Was," filmed in the fall in Atlanta and now streaming.
HCPLive
DECEMBER 10, 2024
A recent study found that loneliness among adults aged 50 80 increased from 2018 to 2022 and dropped in 2023 and 2024.
Science Daily - Heart Disease
DECEMBER 12, 2024
Some patients with diabetes develop a serious condition known as diabetic cardiomyopathy, which is slow and cannot be directly attributed to hypertension or other cardiovascular disorders. This often under-diagnosed heart function impairment is one of the leading causes of death in diabetic patients and it affects both type 1 and type 2 diabetes. There is no current specific drug treatment or clinical protocol approved to address this disease.
Medical Xpress - Cardiology
DECEMBER 9, 2024
People with type 2 diabetes have a higher risk of suffering a stroke, a heart attack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are. Andreas Edsfeldt and Isabel Gonalves, researchers at Lund University Diabetes Centre, have led a study that has mapped out differences in the atherosclerotic process in people who have type 2 diabetes and in people who do not have the disease.
Med Page Today
DECEMBER 11, 2024
(MedPage Today) -- A recent New York Times story described a new fad: "microdosing" GLP-1 anti-obesity drugs like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound). I was asked to discuss the topic on CBS News recently, which gave.
HCPLive
DECEMBER 9, 2024
Pipe discussed findings from the open-label extension of the ATLAS studies at ASH 2024.
Dr. Paddy Barrett
DECEMBER 13, 2024
When it comes to cardiovascular disease, two of the biggest risk factors we must consider are: ApoB concentration - A measure of the number of circulating lipid particles. Visceral Fat & Insulin Resistance - The amount of fat in your abdominal cavity and major organs and how it influences your risk of insulin resistance. It is easy to separate these two factors and attempt to address them independently, but recent studies suggest that there may be a close relationship that we need to be awar
Medical Xpress - Cardiology
DECEMBER 8, 2024
A little of what you fancy does you good unless it's a fizzy drink. Scientists studying the impact of sugar on the risk of cardiovascular disease have found that eating too much added sugar increases your risk of stroke or aneurysm, but eating a few treats is associated with a lower risk of cardiovascular diseases. Meanwhile, drinking sweetened beverages raises your risk of stroke, heart failure, and atrial fibrillation.
Science Daily - Heart Disease
DECEMBER 11, 2024
The majority of children who started smoking tobacco at age 10 years or in their later teens continued to smoke until their mid-twenties. Continuous smoking from childhood significantly increased the risk of premature heart damage, a new study shows.
HCPLive
DECEMBER 9, 2024
Panelists discuss the role of cardiovascular risk management for patients with chronic kidney disease (CKD) and how cardiovascular care can be effectively integrated into CKD management strategies.
Dr. Smith's ECG Blog
DECEMBER 13, 2024
Written by Magnus Nossen and Ken Grauer ( with Comment by Smith ) The ECG in Figure-1 was electronically transmitted by the ambulance service for evaluation. The patient is a young adult male with acute onset of palpitations. He was hemodynamically stable at the time ECG #1 was recorded. QUESTIONS: How would you interpret this ECG? What entities to consider in your differential diagnosis?
Medical Xpress - Cardiology
DECEMBER 13, 2024
Wildfire smoke has long been known to exacerbate health problems like heart disease, lung conditions, and asthma, but now a new study finds that smoke from these fires can lead to poor health thousands of miles away.
Science Daily - Stroke
DECEMBER 12, 2024
Endovascular therapy, a minimally invasive surgery performed inside the blood vessels, is preferred to alternative approaches for vessel obstructions in life-sustaining areas of the brain, analysis suggests.
HCPLive
DECEMBER 9, 2024
HepB-CpG achieved superior seroprotection response versus conventional HepB-alum in patients with HIV and nonresponse to prior hepatitis B vaccination.
Ken Grauer, MD
DECEMBER 12, 2024
I was sent the ECG in Figure-1 initially told only that it was obtained from an older man with palpitations. The cardiology team thought the rhythm was an SVT ( S upra V entricular T achycardia ) with QRS widening as a result of aberrant conduction. QUESTION: Do YOU agree that the rhythm is consistent with an SVT , in which there is QRS widening because of aberrancy?
Medical Xpress - Cardiology
DECEMBER 12, 2024
Cardiovascular problems are the leading cause of disease and mortality worldwide. Plant extracts, rich in bioactive compounds, have contributed significantly to the development of drugs, as they offer therapeutic potential for several of these diseases. However, their use is limited by possible side effects, drugdrug interactions and the lack of scientific evidence from quality preclinical and clinical studies.
Stroke Journal
DECEMBER 12, 2024
Stroke, Ahead of Print. Considerable variation exists in the delivery of acute stroke care and stroke outcomes across settings and population groups. This is attributable in part to variation in resources among emergency departments in the United States, most notably in rural regions. Structural constraints of the US health care system, including the geographic distribution of where patients live relative to the location of hospitals and certified stroke centers, will continue to mean that many
HCPLive
DECEMBER 11, 2024
Investigators developed and validated a novel model to identify liver fibrosis in patients with diabetes which performed better than existing models.
American College of Cardiology
DECEMBER 11, 2024
The following are key points to remember from a state-of-the-art review on revisiting implantable cardioverter-defibrillator (ICD) therapy for primary prevention in patients with heart failure and reduced ejection fraction (HFrEF).
Medical Xpress - Cardiology
DECEMBER 10, 2024
How do human organs develop and what happens to them when they become diseased? To answer these questions, researchers are increasingly focusing on so-called organoids. These mini-organs, just a few millimeters in size, consist of groups of cells cultivated in the laboratory that can form organ-like structures.
European Journal of Heart Failure
DECEMBER 11, 2024
Abstract Worldwide, valvular heart disease (VHD) is a common cause of hospitalization for acute heart failure. In acute heart failure caused by VHD, symptoms result from rapid haemodynamic changes and subsequent decline in cardiac function, and if left untreated, leads to acute decompensation and cardiogenic shock. Current evidence remains scarce and recommendations regarding the management of acute heart failure caused by VHD are lacking in most recent international guidelines.
HCPLive
DECEMBER 9, 2024
In this month's episode of Lungcast, Jacob Sands, MD, discusses the American Lung Associations recently newly-released 2024 State of Lung Cancer report.
American College of Cardiology
DECEMBER 10, 2024
The following are key points to remember from a 2024 American College of Cardiology (ACC) expert consensus decision pathway (ECDP) on strategies and criteria for the diagnosis and management of myocarditis.
Medical Xpress - Cardiology
DECEMBER 10, 2024
Veins in the lungs, or pulmonary veins, play a critical role not only in lung functioning but also in maintaining sufficient oxygen in tissues throughout the body. When a person sustains a pulmonary injury from an illness such as influenza or COVID, repair of blood vessels and the creation of new ones is vital to meet oxygen demands; however, research in these areas remains underexplored.
Stroke Journal
DECEMBER 9, 2024
Stroke, Volume 56, Issue 1 , Page 183-189, January 1, 2025. BACKGROUND:Thrombectomy for acute large vessel occlusion is a well-established treatment for stroke prevention. However, futile recanalization cases, where no-reflow occurs despite successful recanalization, have been reported. This study aimed to assess cerebral hemodynamics immediately after thrombectomy and their relationship with clinical outcomes.METHODS:We prospectively enrolled patients who underwent successful thrombectomy (modi
HCPLive
DECEMBER 8, 2024
At ASH 2024, Annette von Drygalski, MD, PharmD, described the paradigm shift that has taken place in hemophilia over the past decade.
American College of Cardiology
DECEMBER 9, 2024
How do changes in physical activity levels before and after a cancer diagnosis affect the risk of developing cardiovascular diseases (CVDs) in cancer survivors?
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