Sat.Jan 25, 2025 - Fri.Jan 31, 2025

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How Wearable Tech Can Help Monitor Your Heart Health

MIBHS

In the age of technology, wearable devices have revolutionized how we approach health and wellness. From fitness trackers to smartwatches, these gadgets offer users real-time insights into their physical well-being. Among their many benefits, wearable tech has proven to be a game-changer in monitoring heart health, particularly for individuals managing cardiovascular conditions or preparing for minimally invasive or bloodless heart surgery.

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New Study Finds Mechanical Valves Offer Superior Long-Term Survival for Aortic Valve Replacement Patients Aged 60 and Younger

Society of Thoracic Surgeons - Congenital

Press Release New Study Finds Mechanical Valves Offer Superior Long-Term Survival for Aortic Valve Replacement Patients Aged 60 and Younger January 25, 2025 KCummings Sat, 01/25/2025 - 13:33 LOS ANGELESJanuary 25, 2025A late-breaking study presented today at the 2025 Society of Thoracic Surgeons (STS) Annual Meeting reveals that mechanical aortic valve replacements (AVRs) provide significant long-term survival benefits for patients aged 60 and younger compared to bioprosthetic valves.

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GOLD 2025 Report: Addressing Heart Disease in COPD

HCPLive

Panelists discuss how the coexistence of heart disease and chronic obstructive pulmonary disease (COPD) requires careful management as these conditions significantly impact each other. In stable COPD, cardiovascular complications are a leading cause of mortality, whereas acute exacerbations can worsen heart function. Key treatable traits in COPD-associated pulmonary hypertension include hypoxemia, inflammation, and right ventricular dysfunction.

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Patients Who Received Ross Procedure Demonstrate Excellent Survival Rates after 20 Years

Society of Thoracic Surgeons - Adult Cardiac

Press Release Patients Who Received Ross Procedure Demonstrate Excellent Survival Rates after 20 Years January 26, 2025 KCummings Sun, 01/26/2025 - 13:40 LOS ANGELES January 26, 2024 Young patients who have undergone the Ross procedure for aortic valve disease have shown excellent long-term survival, the majority without the need for additional surgery two decades later.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Embolic risk management in infective endocarditis: predicting the 'embolic roulette

Open Heart

Life-threatening complications of infective endocarditis (IE,) are heart failure, uncontrolled infection and embolic events (EE), which pose significant morbidity and mortality risks. EE from vegetation rupture are frequent, occurring in more than 50% of patients and can lead to ischaemic stroke and systemic organ infarctions, contributing to poor patient outcomes.

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New Tool Helps Predict Stroke Outcome with Higher Accuracy

DAIC

tim.hodson Thu, 01/30/2025 - 15:31 Jan. 29, 2025 Researchers atOchsner Health, led byHernan Bazan, MD, DFSVS, FACS, have developed a predictive model with a 93% accuracy rate in determining whether urgent carotid-intervention patients will regain functional independence. This study, Precision in Stroke Care: A Novel Model for Predicting Functional Independence in Urgent Carotid Intervention Patients, is now available in the Journal of the American College of Surgeons.

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Endothelial protease-activated receptor 4: impotent or important?

Frontiers in Cardiovascular Medicine

The protease thrombin, which increases its levels with various pathologies, can signal through the G protein-coupled receptors protease-activated receptors 1 and 4 (PAR1/PAR4). PAR1 is a high-affinity receptor for thrombin, whereas PAR4 is a low-affinity receptor. Finding functions for PAR4 in endothelial cells (ECs) has been an elusive goal over the last two decades.

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A 34 yo Man with chest pain and Zero ST Elevation

Dr. Smith's ECG Blog

Written by Hans Helseth A 34 year old man with no known medical history presented to the ED after an hour of chest pain. He described the pain as a mid sternal "burning sensation" and rated it 8.5 out of 10 at onset, but on presentation to the ED, reported that the pain had improved to 4.5. His first EKG is shown below, with a lead II rhythm strip: EKG 1, 1645 A provisder who is looking for STEMI would not see much in this EKG.

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Clipping Spline Technique Progresses Reproductive Health and Cardiac Development Research

DAIC

The clipping spline provides unprecedented capabilities to see inside 3D images. The clipping spline (mesh) is defined by the control points (green) and provides a smooth cutaway view into the looping embryonic mouse heart, revealing the blood flow (orange and blue) in the hearts atrium and ventricle. Credit : Andre C. Faubert and Shang Wang, Stevens Institute of Technology tim.hodson Tue, 01/28/2025 - 10:45 Jan. 28. 2025 Researchers have developed a new software tool that provides unprecedente

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Specialists’ Individual Treatment Plans for Patients With FCS patients: Pancreatic Specialist

HCPLive

Panelists discuss their specific areas of focus in the care for a patient with familial chylomicronemia syndrome (FCS) as endocrinologists, cardiologists, internists, and pancreatic specialists, outlining primary treatment goals, such as reducing triglyceride levels below 500 mg/dL to lower the risk of acute pancreatitis, and providing recommendations to support optimal collaboration across all specialties involved in managing FCS.

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A study on the global patterns in the design and development of ventricular assist devices: a visualization approach

Frontiers in Cardiovascular Medicine

IntroductionVentricular assist devices (VADs) are lifesavers for people with advanced heart failure. The design of these devices has undergone drastic changes over time with the latest designs being far more efficient, small, lightweight, and more user-friendly. This study aims to analyze publications using bibliometric analysis and see the progress and identify key themes, trends, and collaboration networks.MethodData relevant to this study were obtained from Scopus and Web of Science databases

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Circulating bone morphogenetic protein 10 as a novel marker of atrial stress and remodelling in heart failure

Heart BMJ

Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes. Methods BMP10 levels were quantified in 2085 chronic HF patients from the European BIOlogy Study to TAilored Treatment in Chronic Heart Failure (BIOSTAT-CHF) cohort and in 1

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Study Shows Medtronic ICM Accurately Predicts Risk Thresholds for AFib Patients Using AI

DAIC

tim.hodson Wed, 01/29/2025 - 13:02 Jan. 16, 2025 Primary results from the DEFINE AFib clinical study show the Medtronic LINQ family of insertable cardiac monitors (ICM), paired with a novel algorithm, were able to detect atrial fibrillation episodes and properly risk stratify patients as high risk prior to an AF-related healthcare utilization 80% of the time.

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Ischaemia-reperfusion time differences in ST-elevation myocardial infarction in very young patients: a cohort study

Open Heart

Introduction ST-elevation myocardial infarction (STEMI) is one of the most prevalent presentations in young patients. It is essential to emphasise that each minute of delay in providing medical care is negatively correlated to the patient’s prognosis. The present study was carried out to evaluate the ischaemia-reperfusion times in patients ≤40 years of age versus individuals >40 years of age and their association with mortality and major adverse cardiac event (MACE) over the long

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Systematic review: characteristics of myocarditis followed by fixed drug eruption and dry eye syndrome in patients who have been vaccinated with monkeypox in children and adults

Frontiers in Cardiovascular Medicine

BackgroundThe Monkeypox Virus (MPOX) has caused a surge in viral infections, leading to the WHO recognizing it as a public health emergency of international concern. MPOX infection shares clinical similarities with smallpox but can cause complications like myocarditis, anorectal pain, ocular lesions, kidney damage, or soft tissue superinfection. The study aims to understand the characteristics of myocarditis, fixed drug eruption, and dry eye syndrome in Monkeypox patients.MethodsThis review was

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Age-stratified comparison of heart age and predicted cardiovascular risk in 370 000 primary care patients

Heart BMJ

Background Cardiovascular disease (CVD) preventive medications are recommended for patients at high short-term CVD risk. As most younger people with multiple raised CVD risk factors levels have low short-term risk, they could be falsely reassured to take no action. Heart age—the chronological age of a hypothetical person with the same short-term absolute CVD risk as the patient being assessed, but with an ‘ideal’ risk profile—is a complementary relative CVD risk metric de

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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

Circulation, Ahead of Print. BACKGROUND:The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health.

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How To Show Your Heart Some Love This February

AMS Cardiology

We often associate the month of February with hearts because of Valentines Day. However, there is another reason we should think of hearts in February its American Heart Month, a designated time to advocate for cardiovascular health and raise awareness about heart disease. According to the Centers for Disease Control and Prevention (CDC), one person dies every 34 seconds from heart disease, making this disease the leading cause of death for both men and women of most racial and ethnic groups in

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Cardiovascular outcomes in long COVID-19: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

IntroductionThere is growing evidence that patients with SARS-CoV-2 (The severe acute respiratory syndrome coronavirus 2) may have a variety of cardiovascular complications in the post-acute phase of COVID-19, but these manifestations have not yet been comprehensively characterized.MethodsWe performed a systematic review and meta-analysis of primary research papers which evaluated individuals at least four weeks after confirmed COVID-19 diagnosis and reported on cardiovascular disease prevalence

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Prevalence and relevance of H558R in the efficacy and toxicity of flecainide in patients with atrial fibrillation: a cohort study

Heart BMJ

Background The SCN5A gene polymorphism histidine-558-to-arginine (H558R) has been associated with atrial fibrillation (AF) and may affect the therapeutic effects of flecainide. This study aimed to assess the prevalence of the H558R polymorphism in a European cohort of patients with AF and examine its association with flecainide’s effects on AF recurrence and toxicity.

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Complex high-risk indicated PCI (CHIP-PCI): is it safe to let fellows-in-training perform it as primary operators?

Open Heart

Background Training in complex high-risk indicated percutaneous coronary intervention (CHIP-PCI) has frequently been reserved for established operators (consultants/attending) with trainees (fellows-in-training or FIT) being often discouraged from carrying out such procedures as a primary operator due to their high-risk nature. Whether the outcomes of these cases differ if the primary operator is a supervised FIT compared with a consultant is unknown.

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Why Mechanical AVR Valves Still Matter

CardiacWire

A presentation at this years Society of Thoracic Surgeons (STS) conference suggests mechanical valves might lead to better survival compared to bioprosthetic valves in patients aged 60 or younger undergoing SAVR even though it seems like theyre going out of style. Mechanical SAVR valves have been around in one form or another since the 1960s, but have fallen out of favor in recent years.

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Circulating miRNA-486 as a novel diagnostic biomarker for right ventricular remodeling

Frontiers in Cardiovascular Medicine

ObjectiveClinical practice currently faces a significant shortfall in specific biomarkers needed for diagnosing right ventricular (RV) remodeling in patients with pulmonary hypertension (PH). While small noncoding microRNAs (miRNAs) are crucial regulators of RV remodeling, the biomarker potential of serum miRNAs in this process is little known. This study systematically screened and identified candidate serum miRNAs as potential diagnostic biomarkers for RV remodeling in PH patients.MethodsPulmo

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Improving antiarrhythmic therapy for patients with atrial fibrillation using common genetic variants

Heart BMJ

Many medical specialties have already integrated genetic variants into their clinical decision-making and therapeutic management. While genetic diagnoses take centre stage in clinics for inherited cardiac conditions, common cardiovascular variants still linger in the shadows. The observational cohort study by Trancado et al examines the efficacy and toxicity of flecainide for rhythm control therapy of atrial fibrillation (AF) depending on a common gene polymorphism in the SCN5A gene, histidine-5

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Challenging Rhythms in an 80-something Man

Dr. Smith's ECG Blog

Written by Magnus Nossen and Ken Grauer You are shown the ECG that appears in Figure-1 obtained from an 80-something year old man. Other than sinus rhythm What else do you see in this tracing? Note: The ECG in Figure-1 was initially recorded using the Cabrera Format ( See Comment by Dr. Grauer at the bottom of the page in the October 26, 2020 post for review of the Cabrera Format ).

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Realheart TAH Receives Humanitarian Use Device Designation from FDA

DAIC

tim.hodson Thu, 01/30/2025 - 15:22 Jan. 29, 2025 Scandinavian Real Heart AB (recently aannouncedthat its total artificial heart, Realheart TAH, has been granted Humanitarian Use Device (HUD) designation by the U.S. Food and Drug Administration (FDA). The HUD designation makes Realheart TAH eligible to apply for Humanitarian Device Exemption (HDE), an expedited regulatory pathway that can grant the product limited marketing rights.

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Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial

Frontiers in Cardiovascular Medicine

BackgroundThe efficacy and mechanism of Fufang Danshen dripping pills (FFDS) in the secondary prevention of stable coronary heart disease (SCHD) is currently undetermined. This study aims to investigate the efficacy and preliminary mechanism by which FFDS may impact the progression of SCHD.MethodsBased on randomization, we administered oral FFDS to 30 patients with SCHD in addition to conventional treatment for 30 days.

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New wearable cardiac acoustic monitoring technology for evaluation of subclinical leaflet thrombosis after transcatheter aortic valve replacement

Heart BMJ

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Multidimensional CT (MDCT) is the main imaging mortality for the diagnosis of SLT but it enhances the risk of contrast-induced nephropathy. Our study aimed to use an innovative wearable acoustic cardiography (ACG) device to diagnose SLT as an alternative option.

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Impact of porcelain aorta on outcomes in transfemoral aortic valve implantation (TAVI) with balloon-expandable valves

Open Heart

Background Current guidelines recommend transcatheter aortic valve implantation (TAVI) for patients with aortic stenosis and porcelain aorta (PA). Neurological outcomes of patients with PA undergoing TAVI with modern valves require clarification as most trials examined balloon-expandable valves (BEV) and self-expandable valves in intermediate or high-risk patients, but not specifically in patients with PA.

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Physiology Friday #255: Strength Training for Endurance, Optimal HIIT Protocols, Omega-3s + a Big Announcement!

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. You can find more products I’m affiliated with on my website. Physiologically Speaking is a reader-supported publication.

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Development and validation of a prediction model of hospital mortality for patients with cardiac arrest survived 24 hours after cardiopulmonary resuscitation

Frontiers in Cardiovascular Medicine

ObjectiveResearch on predictive models for hospital mortality in patients who have survived 24h following cardiopulmonary resuscitation (CPR) is limited. We aim to explore the factors associated with hospital mortality in these patients and develop a predictive model to aid clinical decision-making and enhance the survival rates of patients post-resuscitation.MethodsWe sourced the data from a retrospective study within the Dryad dataset, dividing patients who suffered cardiac arrest following CP

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Clot-in-transit and pulmonary embolism: an urgent call for awareness and action

Heart BMJ

Patients with acute pulmonary embolism (PE) have a wide spectrum of clinical presentations, from incidental findings to sudden cardiac death. Management and treatment recommendations in currently available guidelines vary according to patient risk and haemodynamic profile. A clot-in-transit (CiT) in the right heart chambers may be occasionally identified and is, therefore, an under-recognised but challenging condition, often preceding an abrupt clinical deterioration, and associated with increas

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3 Mistakes Most People Make About High Blood Pressure.

Dr. Paddy Barrett

High blood pressure is one of the biggest killers on the planet. As a risk factor, it is responsible for more early deaths than any other risk factor 1. It impacts over 1 billion people. But here is the real problem. It is silent. Most people do not know when they have high blood pressure. And even when they do, it is usually not managed correctly. Getting this wrong is costing lives on a global scale.

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Long-Term Prognostic Implications of Non-Culprit Lesions in Patients Presenting With an Acute Myocardial Infarction: Is It the Angiographic Stenosis Severity or the Underlying High-Risk Morphology?

Circulation

Circulation, Ahead of Print. BACKGROUND:Patients with acute myocardial infarction and angiographically obstructive non-culprit lesions are at high risk for recurrent major adverse cardiac events (MACEs). However, it remains largely unknown whether events are due to stenosis severity or due to the underlying high-risk lesion morphology.METHODS:Between January 2017 and December 2021, 1312 patients with acute myocardial infarction underwent optical coherence tomography of all the 3 main epicardial

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Associations between left atrial indices and cardiorespiratory and muscular fitness among physically active military personnel

Frontiers in Cardiovascular Medicine

BackgroundLeft atrial (LA) size and function are linked to exercise intolerance in heart failure, while associations between LA parameters and exercise performance remain unclear in athletes.ObjectivesThis study aimed to identify correlations between echocardiographic LA size, pressure, stiffness, and composite indices, and various exercise performance indicators.MethodsEchocardiographic parameters were obtained from 181 physically active military personnel receiving regular training and tests f

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Heart age tools are good for raising awareness, but bad for shared decision-making about medication

Heart BMJ

There is something compelling about being told that your heart age is older than your actual age. For this reason, heart age calculators are both numerous and popular, reaching millions of users worldwide. 1 They can be an effective way to engage the general public with an interesting ‘call to action’ in health promotion campaigns, including younger people who may be less aware of heart disease prevention. 2 3 However, a careful review of the evidence shows they are not the magic bul