Sat.May 24, 2025 - Fri.May 30, 2025

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Preterm Infants Treated Early for Patent Ductus Arteriosus Had Worse Outcomes

Med Page Today

(MedPage Today) -- Active treatment of hemodynamically significant patent ductus arteriosus (PDA) in preterm infants within the first 2 weeks of life was associated with worse outcomes than expectant management, a meta-analysis suggested. In the.

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Timely initiation of statin therapy for diabetes shown to dramatically reduce risk of heart attack and stroke

Science Daily - Heart Disease

Taking a statin medication is an effective, safe, and low-cost way to lower cholesterol and reduce risk of cardiovascular events. Despite clinicians recommending that many patients with diabetes take statins, nearly one-fifth of them opt to delay treatment. In a new study, researchers found that patients who started statin therapy right away reduced the rate of heart attack and stroke by one third compared to those who chose to delay taking the medication.

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Diabetes Dialogue: INHALE-3 Trial and Afrezza, With Roy Beck, MD, PhD

HCPLive

In this episode, hosts explore technosphere inhaled insulin (Afrezza) in comparison to standard diabetes therapies in the INHALE-3 trial.

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Intravenous tenecteplase beneficial before endovascular thrombectomy

Medical Xpress - Cardiology

For patients with acute ischemic stroke due to large-vessel occlusion who present within 4.5 hours, intravenous tenecteplase before endovascular thrombectomy is associated with higher functional independence at 90 days, according to a study published online May 21 in the New England Journal of Medicine to coincide with the annual European Stroke Organisation Conference, held from May 21 to 23 in Helsinki.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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AI vs. human. Can the use of artificial intelligence in Holter ECG testing replace a specialist?

Cardiomatics

In a world where rapidly developing Artificial Intelligence (AI) is entering more spheres of life, questions about its use are beginning to arise. With ongoing changes in the job market, many employees across various industriesincluding healthcareare beginning to feel the impact. One notable shift is the increasing use of AI to analyse medical data and accelerate the work of specialists.

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Where there’s smoke, there’s fire – and heart health risks

American Heart News - Heart News

DALLAS, May 30, 2025 Smoke from Canada wildfires is rapidly drifting into the U.S. and the American Heart Association, a global force changing the future of health for all, warns that this wildfire smoke exposure may pose an increased risk for heart.

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Just three nights of poor sleep might harm your heart: New study

Medical Xpress - Cardiology

We've long known that a lack of sleep is bad for the heartbut scientists are now starting to understand exactly how it causes harm.

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Impact of sodium–glucose transport protein-2 (SGLT2) inhibitors on the inflammasome pathway in acute myocardial infarction in type 2 diabetes mellitus: a comprehensive review

Cardiovascular Diabetology

Sodiumglucose transport protein-2 (SGLT2) inhibitors, initially developed for glycemic control in type 2 diabetes mellitus (T2DM), have emerged as potential cardioprotective agents, reducing cardiovascular mo.

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Understanding cultural differences in salt usage may help lower consumption

American Heart News - Heart News

Research Highlights: An analysis of data from a national health survey conducted before the pandemic found that pizza, soup and chicken are some of the main sources of sodium (salt) intake for people in all racial and ethnic groups. The study also.

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LAP May Predict Risk of Hyperuricemia and Gout

HCPLive

New research highlights Lipid Accumulation Product as a key predictor for gout and hyperuricemia, offering a modifiable risk factor for prevention.

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AMI Could Carry Higher Risk of Hematologic Malignancies

American College of Cardiology

Patients with new acute myocardial infarction (AMI) had a 49% higher risk of hematologic malignancies, according to original research published May 27 in JACC: CardioOncology.

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Validation and Feasibility of PETS-Stroke: A Patient-Reported Measure of Treatment Burden After Stroke

Stroke Journal

Stroke, Ahead of Print. BACKGROUND:Treatment burden is the workload of health care for people with long-term conditions and the impact on wellbeing. A validated measure of treatment burden for use as an outcome measure in stroke trials is needed. We adapted a patient-reported measure of treatment burden in multimorbidity, Patient Experience With Treatment and Self-Management (PETS), version 2.0, to create a stroke-specific measure, PETS-stroke, and examined its psychometric properties.METHODS:We

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AHA Looks to Advance Access to Clinical Trials for Cardiomyopathy

DAIC

tim.hodson Tue, 05/27/2025 - 11:01 May 27, 2025 Despite scientific advances in cardiovascular care, people in living in rural areas and other communities with long-term economic or social challenges still face barriers to cutting-edge therapies such as gene editing, according to a 2020 American Heart Association presidential advisory. To address gaps in care, the Association, devoted to changing the future of health for all, is using its Get With The Guidelines data to support patient populatio

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How to Address Food Allergy Anxiety with Proximity Challenges

HCPLive

Katherine Dahlsgaard, PhD, and Megan Lewis, MSN, discuss how proximity challenges can reduce medically unnecessary avoidance for patients with food allergy anxiety.

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The influence of psychological intervention-assisted cardiac rehabilitation on kinesiophobia in individuals diagnosed with coronary heart disease

Frontiers in Cardiovascular Medicine

ObjectiveKinesiophobia is prevalent among patients with coronary heart disease (CHD). This study aimed to explore whether psychologically-informed cardiac rehabilitation (CR) could positively influence the reduction of kinesiophobia in CHD patients.MethodsA total of 86 CHD patients, who sought treatment at Bethune International Peace Hospital between June 2022 and June 2023, were selected and divided into two groups: a psychological intervention group comprising 42 patients and a conventional CR

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SWEDEHEART Registry Tracks Rise in Complete Revascularization, Physiology-Guided Procedures

American College of Cardiology

Use of complete revascularization (CR) and physiology-guided procedures has increased over time in patients with STEMI and multivessel disease (MVD), with half of patients in 2021 undergoing CR vs. incomplete revascularization (IR), and physiology-based guidance was used in 14%.

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Impact of aortic landing zone geometry on TAVI implantation depth: comparison between ACURATE neo2 and Portico/Evolut

Open Heart

Background During transcatheter aortic valve implantation (TAVI), increased aortic angulation can affect the final implantation depth of self-expandable (SE) devices due to the interaction between the high stent frame and the targeted aortic landing zone (LZ). We herein sought to investigate the behaviour of the ACURATE neo 2, a SE device with a unique release mechanism, in relation to patient-specific angulation and curvature of the aortic LZ.

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RAD 2025 Conference: Abstracts to Watch

HCPLive

This summary features a variety of abstracts to be presented at the RAD meeting in June 2025, highlighting new data in atopic dermatitis and the dermatology space in general.

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Adverse effects of finerenone in patients with heart failure: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine

BackgroundFinerenone has been shown to improve outcomes in patients with heart failure (HF), encompassing those with reduced (HFrEF), mildly reduced (HFmrEF), or preserved ejection fraction (HFpEF). However, its clinical use is accompanied by notable adverse effects. This study aimed to evaluate the relative risks of adverse events associated with finerenone across HF phenotypes.MethodsA systematic search of PubMed, Embase, and Web of Science identified six randomized controlled trials involving

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Dr. Richard Wright and Dr. C. Michael Gibson discuss: Transthyretin tetramer destabilization and increased mortality, and the physiologic importance of TTR.

Clinical Trial Results

Disclosures: Sponsored by BridgeBio Pharma, Inc

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Target Heart Rate – What You Need to Know

MIBHS

Whether youre starting a new exercise program or trying to take your cardiovascular fitness to the next level, understanding your target heart rate is crucial. Its the compass that helps you navigate your workouts, ensuring youre working hard enough to see results, but not so hard that you put unnecessary strain on your heart muscle. In this post, well walk you through the science and practical tips for finding and using your target heart rate zone to maximize the benefits of physical activityes

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The Medical Sisterhood: Expertise into Influence—Owning the Podium in Dermatology, with Amy Spizuoco, DO

HCPLive

Amy Spizuoco, DO, joins the show to discuss her journey as a key opinion leader in dermatology.

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The gut-heart axis: unveiling the roles of gut microbiota in cardiovascular diseases

Frontiers in Cardiovascular Medicine

The gut microbiome refers to the collective genomes of the approximately 1,0001,150 microbial species found in the human gut, called the gut microbiota. Changing the gut microbiota composition has been shown to affect cardiovascular health significantly. Numerous studies have demonstrated the part that gut microbiota and its metabolites play in the development and course of several illnesses, including colon cancer, heart failure, stroke, hypertension, and inflammatory bowel disease.

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Top EHR Features for Cardiovascular Chronic Care Management

GEMMS

Managing chronic cardiovascular conditions presents unique challenges and opportunities. As the prevalence of heart disease, hypertension, and heart failure continues to rise, cardiology practices must adopt innovative solutions to provide effective, coordinated care. Electronic Health Records (EHR) systems play a pivotal role in this transformation, offering tools that streamline workflows, enhance patient engagement, and ensure compliance with complex billing requirements.

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Physiology Friday #272: Is Endurance Exercise the Best Way to Improve Longevity?

Physiologically Speaking

Greetings! Welcome to the Physiology Friday newsletter. As most of you know by now, I’m a huge fan of creatine. I take it to support my performance and recovery and have so for about a year. There’s some pretty compelling evidence that this supplement can support your brain and body through several mechanisms, and it’s very low-risk.

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Assessing Systemic Sclerosis With AI Deep Neural Networks

HCPLive

AI revolutionizes systemic sclerosis diagnosis, enhancing treatment tracking and potentially improving patient outcomes through innovative deep neural network analysis.

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ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels

Frontiers in Cardiovascular Medicine

BackgroundThe widespread use of zinc oxide nanoparticles (ZnO NPs) has raised safety concerns on human health. However, the effects and underlying mechanisms of ZnO NPs exposure on the heart, especially during acute exposure, have yet to be elucidated.MethodsTwo different sizes of ZnO NPs (40 nm and 100 nm) were selected and their in vivo effects on mouse heart were evaluated by echocardiography and electrocardiograms.

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Depression Risk After Diagnosis of a Medical Condition; Fatty Liver and Pregnancy

Med Page Today

(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.

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Assessing the psychometric properties of generic (EQ-5D-5L) and disease-specific (KCCQ) quality of life in patients with hypertrophic cardiomyopathy in the AFFECT-HCM study

Open Heart

Background To assess the psychometric properties (content validity, reliability and construct validity) of generic and disease-specific health-related quality of life (HRQoL) instruments in patients with hypertrophic cardiomyopathy (HCM) and genotype-positive, phenotype-negative (G+/P–) individuals. Methods As part of the multicentre, observational AFFECT-HCM study, HRQoL was measured using the generic EuroQoL-5 Dimension-5 Level (EQ-5D-5L) questionnaire, the Visual Analogue Scale (EQ VAS)

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Optimal Timing for Hen’s Egg Oral Food Challenge in FPIES May Be Age 2 Years

HCPLive

Study suggests age 2 may be optimal for hens egg oral food challenge in FPIES. Early OFCs linked to higher risk of positive results in Turkish pediatric cohort.

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Methods and validity indicators for measuring adherence and persistence to aspirin in secondary cardiovascular prevention: a systematic review

Frontiers in Cardiovascular Medicine

BackgroundAspirin (acetylsalicylic acid, ASA) is widely recommended for long-term secondary cardiovascular prevention (SCP), but its clinical effectiveness depends on patient adherence, which remains suboptimal. Understanding how adherence and persistence to ASA are measured is essential to improving outcomes. This systematic review aimed to identify the methods used to assess adherence and persistence to ASA in SCP and evaluate their validity indicators.MethodsWe systematically searched EMBASE,

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The Truth About Muscle Loss and Weight Loss Drugs.

Dr. Paddy Barrett

The benefits of weight loss medications for those who need them are crystal clear. Weight loss of between 15-25%. Lower Blood Pressure. Prevention of diabetes. Fewer cardiovascular events. Less liver fat. Less insulin resistance. The list goes on, but you get the point. But as Thomas Sowell so famously said about all things in life: “There are no solutions, only trade-offs.” Every medication has the potential to cause adverse effects, and weight loss medications are no different.

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Artificial Heart Receives Breakthrough Device Designation from FDA

DAIC

tim.hodson Fri, 05/30/2025 - 11:57 May 30, 2025 BiVACOR , a clinical-stage medical device company developing the worlds first titanium Total Artificial Heart (TAH), announced that its device has received Breakthrough Device Designation from the U.S. Food and Drug Administration (FDA). The designation supports the BiVACOR TAH as a bridge to transplant (BTT) for adults with severe biventricular or univentricular heart failure where current treatments, including LVADs, are not viable.

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Using AI to Explore CPAP’s Impact on Abdominal Obesity in OSA, with Jennifer Prevot, MD

HCPLive

Prevot describes her research exploring the relationship between OSA severity and abdominal obesity metrics as well as changes in both metrics following CPAP.

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Cryo-ablation management of atrial fibrillation in Fabry disease without agalsidase alpha: a case report

Frontiers in Cardiovascular Medicine

Fabry disease (FD) is a rare genetic disorder caused by mutations in the GLA gene, affecting multiple organs. Over 60% of patients experience heart-related issues, primarily arrhythmias. Unlike typical cases, these arrhythmias are complex and often do not respond well to standard antiarrhythmic drugs, sometimes worsening symptoms. This paper presents a case study of a FD patient with paroxysmal atrial fibrillation successfully treated using bilateral pulmonary vein cryoablation, resulting in pos

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Endothelial Dysfunction and Chronic Cannabis Use

JAMA Cardiology

This cross-sectional study aims to determine whether cannabis use is associated with vascular endothelial function.

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