Open Heart

JANUARY 20, 2025

Introduction Cardiac rehabilitation (CR) programs are essential for the recovery and secondary prevention of cardiovascular diseases. Despite the proven benefits of such programs, participation and completion rates remain suboptimal. This systematic review aims to identify literatures that systematically analyse and synthesize the factors and barriers influencing patients’ participation in cardiac rehabilitation programs.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Education Cardiovascular Disease Research 52

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

ObjectiveTo quantify the risk of heart diseases (HD) and determine the relationship between physical activity (PA) dimensions and HD among Chinese middle-aged and older individuals.MethodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS, 2018), 16,927 participants were included in this study. Multivariate logistic regression was performed to determine the association between HD risk and PA dimensions, including volume, intensity, frequency, and duration.

Heart Disease 52

Heart Disease Research 52

Medical Xpress - Cardiology

JANUARY 24, 2025

Researchers from Mass General Brigham and collaborating institutions have developed a non-invasive approach to manipulate cardiac tissue activity by using light to stimulate an innovative ink incorporated into bioprinted tissue. Their goal is to develop a technique that can be used to repair the heart. Their findings in preclinical models, published in Science Advances, show the transformative potential of non-invasive therapeutic methods to control electrically active tissues.

Innovation 130

Innovation Research 130

Science Daily - Heart Disease

JANUARY 22, 2025

Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The breakthrough science focused on replicating heart tissues, bringing research closer to generating functional, bioprinted organs, which would have broad applications in disease modelling, drug screening and regenerative medicine.

Research 129

Research 129

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

Open Heart

JANUARY 20, 2025

Introduction Cardiovascular rehabilitation (CR) is a crucial intervention in secondary prevention, aimed at stabilizing clinical conditions and reducing future cardiovascular events. CR is a class 1 recommendation for all patients with coronary artery disease (CAD). Objective This study evaluates the impact of CR on modifying coronary risk factors in patients who underwent Coronary Artery Bypass Grafting (CABG) or received non-surgical interventions like medical therapy or percutaneous coronary

Risk Factors 52

Risk Factors Cardiac Rehabilitation Coronary Artery Bypass Graft Coronary Artery Disease 52

DAIC

JANUARY 24, 2025

tim.hodson Fri, 01/24/2025 - 11:51 Jan. 24, 2025 In-patients undergoing coronary artery bypass grafting (CABG), a novel analysis evaluating surgeon preference for multi- versus single-arterial grafting may help explain the differing results between prior retrospective analyses and randomized controlled trials regarding long-term survival. A study presented at The Society of Thoracic Surgeons 61st Annual Meeting explores findings in more than a million U.S.

Outcomes 52

Outcomes Coronary Artery Bypass Graft Cardiothoracic Medicare 52

European Journal of Heart Failure

JANUARY 20, 2025

Remote patient monitoring in heart failure (HF). Abstract Aims Methods of non-invasive remote patient monitoring (RPM) for heart failure (HF) remain diverse. Understanding factors that influence the effectiveness of RPM on HF-related and all-cause hospitalizations, mortality, and emergency department visits is crucial for developing successful RPM interventions.

Heart Failure 40

Heart Failure Hospital Education Technology 40

Open Heart

JANUARY 19, 2025

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain. Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients.

Cardiogenic Shock 52

Cardiogenic Shock Aortic Stenosis Aortic valve 52

DAIC

JANUARY 24, 2025

tim.hodson Fri, 01/24/2025 - 11:03 Jan. 22, 2025 Anthos Therapeutics, Inc., aclinical-stage biopharmaceutical company developing therapies to treatcardiovascular metabolic diseases, founded by Blackstone Life Sciences, has published the results of the landmark AZALEA-TIMI 71 study in the January 23 issue of the New England Journal of Medicine (NEJM).

AFIB 52

AFIB Atrial Fibrillation General Cardiology Strokes 52

Frontiers in Cardiovascular Medicine

JANUARY 22, 2025

BackgroundHeart failure (HF) is a clinical syndrome resulting from structural damage or dysfunction of the heart. Previous investigations have highlighted the critical involvement of immune cells in the progression of heart failure, with distinct roles attributed to different types of immune cells. The objective of the current research was to explore the potential connections between immune characteristics and the development of HF, as well as to ascertain the nature of the causality between the

Heart Failure 52

Heart Failure Research 52

Science Daily - Heart Disease

JANUARY 19, 2025

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their body mass index, according to new research. This 'intermuscular' fat is highly prized in beef steaks for cooking. However, little is known about this type of body fat in humans, and its impact on health.

Heart Disease 113

Heart Disease Heart attacks Heart Attack Heart Failure 113

Open Heart

JANUARY 20, 2025

Introduction Peripartum cardiomyopathy (PPCM) is a cardiovascular condition that occurs during late pregnancy or within five months postpartum, often leading to poor clinical outcomes. The global incidence of PPCM is estimated to range from 1 in 100 to 1 in 20,000 live births, depending on the population and geographic region. Identifying predictors of poor clinical outcomes in PPCM is essential for optimizing care management and improving the prognosis of affected patients.

Cardiomyopathy 52

Cardiomyopathy Outcomes Blood Pressure Tachycardia 52

CardiacWire

JANUARY 22, 2025

Although GLP-1s have proven to significantly help with weight loss and cardiometabolic disorders, a new Nature Medicine study shed light on the drugs potential side-effects. GLP-1s have skyrocketed in popularity due to their weight loss impact, while their potential heart benefits could make GLP-1s a common cardiology drug. However, little is known about the long-term risks of this wonder drug class due to its relatively short time on the market and a lack of studies on the topic.

Obesity 59

Obesity Cardiac Arrest Dementia Outcomes 59

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

Background Early prediction of heart failure (HF) after acute myocardial infarction (AMI) is essential for personalized treatment. We aimed to use interpretable machine learning (ML) methods to develop a risk prediction model for HF in AMI patients.MethodsWe retrospectively included patients initially with AMI who received percutaneous coronary intervention (PCI) in our hospital from November 2016 to February 2020.

Myocardial Infarction 52

Myocardial Infarction Heart Failure Research Hospital 52

HCPLive

JANUARY 24, 2025

Panelists discuss how dysbiosis of the lung microbiome can exacerbate chronic obstructive pulmonary disease (COPD) through increased inflammation and altered immune responses. In contrast, chest CT imaging is indicated for patients with severe COPD, suspected comorbidities, surgical planning, or unexplained symptoms despite standard treatment. These factors highlight the complexity of COPD management.

Pulmonary 59

Pulmonary 59

Open Heart

JANUARY 20, 2025

Introduction Myxomas are the most frequent type of benign tumour of the heart, typically found in the left atrium. We present a case of myxoma with cardioembolic stroke coexisting with coronary artery disease. Case Presentation 39-year-old man, active smoker with bilateral sensorineural hearing loss, and dyslipidaemia presented with dizziness. After initial treatment failed, CT brain and perfusion scan revealed left cerebellar infarct and right parietal haemorrhage.

Coronary Artery Disease 52

Coronary Artery Disease Strokes Stroke Embolism 52

Ken Grauer, MD

JANUARY 24, 2025

I was sent the ECG in Figure-1 without clinical information. I interpreted the rhythm as AFib ( A trial F ibrillation ). QUESTION: Do you see anything else? Figure-1: The initial ECG in today's case. Take another LOOK. To facilitate description I've numbered the beats in Figure-2. Figure-2: I've numbered the beats from Figure-1. Confession: I initially looked at this tracing too quickly.

Blog 95

Blog AFIB Ablation Strokes 95

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

Accurate evaluation of coronary artery pathology is essential for risk stratification and tailoring appropriate treatment. Intravascular imaging was introduced for this purpose 40 years ago enabling for the first time in vivo plaque characterization. Since then, several studies have evaluated the efficacy of the existing intravascular imaging modalities in assessing plaque pathology and composition and their potential in guiding intervention and predicting vulnerable plaques.

Plaque 52

Plaque 52

Physiologically Speaking

JANUARY 24, 2025

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. You can find more products I’m affiliated with on my website. Physiologically Speaking is a reader-supported publication.

Physiology 64

Physiology Diet Exercise BMI 64

Open Heart

JANUARY 20, 2025

Introduction Hypertension is a major risk factor for cardiovascular disease. World Health Organization (WHO) stated that hypertension affects 1.28 billion of the population globally, with high prevalence in Malaysia. Effective management is crucial for reducing complications, yet inadequate patients’ knowledge may hinder treatment adherence. Therefore, this study aimed to assess the level of knowledge on hypertension and its relationship with socio-demographic characteristics among adult h

Hypertension 52

Hypertension Education Risk Factors Public Health 52

Dr. S. Venkatesan MD

JANUARY 24, 2025

Wars and scientific debates do not end that easily. Parallel to the Vietnam war days of 1970s to the current Ukraine-Russia conflict of 2025, one silent academic war is going on, in the conflict-ridden corridors of cardiology and cardiac surgery. (The CASS study of 1970s to the ORBITA era of 2025) Any amount of scientific literature, debates, guidelines, failed to tick the right choice of revascularisation in chronic CAD.

Academic 52

Academic Hospital Outcomes 52

Frontiers in Cardiovascular Medicine

JANUARY 23, 2025

The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. While this occurrence was once rare, the growing number of patients undergoing this procedure has made it more prevalent. The actual frequency of pulmonary vein (PV) occlusion remains a topic of debate.

Atrial Fibrillation 52

Atrial Fibrillation Stenosis Pulmonary Ablation 52

Dr. Smith's ECG Blog

JANUARY 19, 2025

OMI Manifesto About Resources Teaching Images Lectures + Podcasts Rules + Equations OMI Literature Timeline OMI Facts and References The OMI Quizzes OMI Pocket Guide Cardiac CATH Guide QTc Calculator Lead Reversals-Artifact Neuroprotective CPR OMI AI: The Queen of Hearts Sunday, January 19, 2025 Case from Cortland Ashbrook in FB Messenger Posted by Steve Smith at 10:36 AM Email This BlogThis!

STEMI 52

STEMI Tachycardia Chest Pain Atrial Fibrillation 52

Open Heart

JANUARY 20, 2025

Introduction Atherosclerotic Cardiovascular Disease (ASCVD) remains a leading cause of global cardiovascular mortality, responsible for 80% of related deaths. Lowering low-density lipoprotein cholesterol (LDL-C) is crucial in mitigating atherosclerotic plaque progression and reducing ASCVD incidence. Objective The primary objective of this study is to assess the effectiveness of the Cardiovascular Risk Reduction Clinic (CRRC) at Hospital Pulau Pinang in achieving risk-based LDL-C targets in pati

Hospital 52

Hospital Education Plaque Cholesterol 52

Nature Reviews - Cardiology

JANUARY 19, 2025

Nature Reviews Cardiology, Published online: 20 January 2025; doi:10.1038/s41569-025-01118-1 The past 20 years have witnessed remarkable progress in the evolution of transcatheter procedures for the treatment of adult patients with congenital heart disease. In this Review, Rods-Cabau and colleagues provide a comprehensive overview of the available transcatheter interventions for these patients, focusing on their current indications and associated outcomes.

Congenital Heart Disease 92

Congenital Heart Disease Congenital Heart Disease Outcomes 92

Frontiers in Cardiovascular Medicine

JANUARY 21, 2025

Atrial fibrillation is the most prevalent arrhythmia with a lifetime risk of nearly 30%. It can be associated with reduced quality of life and complications such as heart failure and stroke. Pulmonary vein isolation (PVI) is the most effective treatment for rhythm control. It has initially been performed with fluoroscopic catheter guiding. The advent of three-dimensional (3D) electro-anatomical mapping has significantly reduced the need for fluoroscopy.

Atrial Fibrillation 52

Atrial Fibrillation Quality of Life Ablation Electrophysiology 52

Dr. Smith's ECG Blog

JANUARY 21, 2025

I was reading ECGs on the system and saw all of these, from one patient. I read them without clinical context and looked at the clinical context later. A 70-something dialysis patient presented and coronary disease had missed dialysis and then presented with acute onset of shortness of breath. He denied chest pain. There was mild hypoxia prehospital, lowest saturation 90%, On arrival, BP was 140/84, pulse 122, O2sat 100% and the patient had increased work of breathing.

Chest Pain 66

Chest Pain STEMI Tachycardia Myocardial Infarction 66

Open Heart

JANUARY 20, 2025

Introduction ST-Elevation Myocardial Infarction (STEMI) accounted for 43.3% of Acute Coronary Syndromes (ACS) in Malaysia in 2019. Malaysia uses thrombolysis, specifically streptokinase, for acute STEMI reperfusion, even though Primary Percutaneous Coronary Intervention (PPCI) is the gold standard. This study investigates thrombolysis results and Primary Percutaneous Coronary Intervention (MACE) risk variables.

Thrombolysis 52

Thrombolysis Myocardial Infarction Cardiogenic Shock Cardiac Arrest 52

HeartRhythm

JANUARY 23, 2025

Pulsed-field ablation (PFA) offers notable advantages in atrial fibrillation (AF) ablation by selectively targeting cardiomyocytes via an irreversible electroporation mechanism, thereby minimizing damage to surrounding tissues. Although clinical studies demonstrate that PFA is both safe and effective, PFA-mediated hemolysis and potential acute kidney injury (AKI) development have been recently reported.

Atrial Fibrillation 40

Atrial Fibrillation Ablation Risk Factors 40

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

AimThe association between red cell distribution widthalbumin ratio (RAR) and the risk of all-cause mortality in intensive care unit (ICU) patients with heart failure remains uncertain. This study aimed to investigate this association.MethodsClinical data from MIMIC- (version 2.2) database was utilized for the analysis of ICU patients with heart failure.

Heart Failure 52

Heart Failure ICU Physiology Outcomes 52

Dr. Smith's ECG Blog

JANUARY 24, 2025

Written by Willy Frick A 52 year old man with hypertension, dyslipidemia, and seropositive rheumatoid arthritis (a risk factor for CAD) presented with acute substernal chest pressure with diaphoresis which woke him from sleep just after midnight. He said it felt like "someone ripped [his] heart out." Ominous. While walking into the ED, the patient had an episode of "dizziness" causing him to fall onto his stomach.

Chest Pain 131

Chest Pain STEMI Risk Factors Coronary Artery Disease 131

Open Heart

JANUARY 19, 2025

Introduction Data on the characteristics and outcomes of pregnancy and among patients with Fontan physiology are limited. We aimed to evaluate the immediate and long-term outcomes among these patients who were followed at our centre. Methods We included adult patients who had undergone Fontan surgery for congenital heart disease and were pregnant between 1994 and 2021.

Congenital Heart Disease 52

Congenital Heart Disease Outcomes Physiology Arrhythmia 52

Dr. S. Venkatesan MD

JANUARY 22, 2025

ACS is one of the sinister diagnoses made at medical ER. The fear comes built in with the diagnosis often amplified by young felllows on call (& often times by senior consultants as well) It may appear real, from a clinical angle, but trust, when we deal with the whole gamut of so-called ACS (other than STEMI), there is indeed a benign face in many of them.

Coronary Angiogram 52

Coronary Angiogram Chest Pain Anatomy Outpatient 52

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

BackgroundImproving medication compliance and self-efficacy in hypertensive patients is of significant importance for their prognosis. This meta-analysis aimed to assess the role of motivational interviewing in reducing systolic and diastolic blood pressure, self-efficacy, quality of life and medication adherence in hypertensive patients.MethodsTwo authors searched PubMed, Cochrane Library, Clinicaltrials, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical

Hypertension 52

Hypertension Quality of Life Blood Pressure Article 52

CardiacWire

JANUARY 24, 2025

Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. Current guidelines recommend direct-acting oral anticoagulants (DOACs) for AF because they reduce ischemic stroke with a lower risk of brain hemorrhage.

Strokes 59

Strokes Stroke AFIB Thrombosis 59

Open Heart

JANUARY 20, 2025

Introduction Cardiac rehabilitation is a structured program provided to patients with major cardiovascular diseases, shown to enhance functional capacity, reduce morbidity and mortality rate worldwide. However, in Malaysia, the availability of such programs is limited due to disparities in healthcare access. This led to our objective of testing a newly developed AI-based home health monitoring cardiac rehabilitation application (ORCUS) designed to improve patients’ functional status.

Cardiac Rehabilitation 52

Cardiac Rehabilitation Heart Disease Exercise Angina 52