Sat.May 03, 2025 - Fri.May 09, 2025

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Shingles vaccine lowers the risk of heart disease for up to eight years

Science Daily - Heart Disease

People who are given a vaccine for shingles have a 23% lower risk of cardiovascular events, including stroke, heart failure, and coronary heart disease, according to a recent study of more than a million people. The protective effect of the vaccine lasts for up to eight years and is particularly pronounced for men, people under the age of 60 and those with unhealthy lifestyles.

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Oral Obicetrapib Takes Lipid Lowering to Another Level in Trials

Med Page Today

(MedPage Today) -- Obicetrapib provided dramatic reductions in LDL cholesterol, without noticeable side effects, in a phase III trial of high-risk individuals already on maximal lipid-lowering therapy. In adults with heterozygous familial hypercholesterolemia.

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Study Highlights Cardiovascular Safety of Systemic Therapies for Psoriasis

HCPLive

This analysis highlighted the cardiovascular safety of systemic psoriasis drugs using a prospective cohort trial design.

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Cardiomatics Arseus Medical Partnership

Cardiomatics

We are proud to announce our partnership with Arseus Medical , a leading distributor of medical technology in the Benelux region. This partnership brings innovation straight to cardiology clinics across the Netherlands and Belgium. What the Cardiomatics Arseus Medical Partnership Means Together with Arseus Medical, Cardiomatics is now part of a unified, end-to-end solution for cardiac diagnostics combining high-quality Holter recorders with AI-powered ECG interpretation in one integrated offeri

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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A crown, a crowd and a standing ovation

Heart Sisters

"Out of the 700+ scientific papers presented at my first national cardiology conference, only four focused specifically on women's heart disease. FOUR!? Out of HUNDREDS!?" As you might guess, hearing that appalling news became the real story behind that conference for me.

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Heart rhythm disorder traced to bacterium lurking in our gums

Science Daily - Heart Disease

New research shows that the gum disease bacterium P. gingivalis can slip into the bloodstream and infiltrate the heart. There, it quietly drives scar tissue buildup -- distorting the heart's architecture, disrupting electrical signals, and raising the risk of atrial fibrillation.

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The Diabetic Supplies Gray Market Is Ripe for Disruption

Med Page Today

(MedPage Today) -- "CA$H 4 SEALED & UNEXPIRED DIABETIC TEST STRIPS -- CALL NOW." This message, printed in black on a neon yellow poster board, hangs just outside the $1.1 billion Charlotte R. Bloomberg Children's Center at Johns Hopkins.

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Invited Article: Al guided Dual Antiplatelet Therapy and Anticoagulation

Journal of Cardiovascular Pharmacology

Artificial intelligence (AI) has emerged as a transformative tool in healthcare through data analysis, pattern recognition and predictive modeling capabilities. AI-driven approaches have the potential to positively transform patient care through personalized treatment regimens comprising antiplatelet and anticoagulant therapy. This review explores the integration of AI in guiding antithrombotic therapies, highlighting the potential to improve patient outcomes through personalized medicine.

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Commercial Implant Experience of a Helix‐Fixation Dual‐Chamber Leadless Pacemaker

Journal of Cardiovascular Electrophysiology

Dual-chamber leadless pacemakers were implanted successfully in 99.4% of patients, with a mean total procedure time of 64.3min, mean implant-to-implant communication success in >90% of beats, and a 30-day complication-free rate of 98.9%. ABSTRACT Introduction The AVEIR DR pacemaker (Abbott) is a dual-chamber leadless pacemaker (LP) system that includes right atrial and right ventricular helix-fixation LPs (ALP, VLP), with atrioventricular synchrony maintained via wireless communication betwee

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Shared Decision-Making Needed to Address Environmental, Social Factors of Asthma Management

HCPLive

Explore innovative strategies for asthma management that prioritize shared decision-making and address environmental, social, and behavioral factors.

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Zoster Vax & Heart Disease; Jewel WCD OK'd; Carotid Revascularization for Low-Risk?

Med Page Today

(MedPage Today) -- In a nationwide Korean study, live zoster vaccination was linked with lower risks of heart disease, including major adverse cardiovascular events, heart failure, ischemic heart disease, and other outcomes. (European Heart Journal.

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FAVOR III Europe Trial: Quantitative Flow Ratio vs. Fractional Flow Reserve For Coronary Revascularization Guidance

American College of Cardiology

FAVOR III Europe (Functional Diagnostic Accuracy of Quantitative Flow Ratio in Online Assessment of Coronary Stenosis III Europe) was a multicenter, randomized, open-label, noninferiority trial to compare clinical outcomes of quantitative flow ratio (QFR)-guided and fractional flow reserve (FFR)-guided revascularization in patients with intermediate coronary stenosis (40-90% diameter stenosis by visual estimation) at 12 months.

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Obicetrapib Puts on a Show

CardiacWire

Results from NewAmsterdam Pharmas Phase 3 BROADWAY and TANDEM trials suggest that obicetrapib could be an effective LDL-C lowering treatment , both on its own or combined with another drug. TANDEM examined the effects of a fixed-dose obicetrapib/ezetimibe combination therapy and found An LDL-C reduction of ~50% at day 84 of treatment compared to placebo.

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Adding Upadacitinib to the Treatment Landscape of GCA, with Daniel Blockmans, MD, PhD

HCPLive

Blockmans discussed data supporting upadacitinibs new indication and why the approval is important for patients with giant cell arteritis.

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Does Coronary Calcium Mean the Same in Active and Sedentary Individuals?

Circulation

Circulation, Volume 151, Issue 18 , Page 1309-1311, May 6, 2025.

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Viet Le, DMSc, MPAS, PA-C, FACC, Named CardioSmart Editor

American College of Cardiology

The ACC has named Viet Le, DMSc, MPAS, PA-C, FACC, to lead its CardioSmart patient engagement program.

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Four-dimensional flow provides incremental diagnostic value over echocardiography in aortic stenosis

Open Heart

Aims Four-dimensional flow cardiovascular MRI (4D flow CMR) has emerged as a promising technique for assessing aortic stenosis (AS). This study aimed to evaluate the agreement between 4D flow CMR and transthoracic echocardiography (TTE) in estimating peak aortic valve (AV) velocities (V Peak ), grading AS severity and predicting AV intervention in a real-world setting.

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Cannabis Use, Dependence Linked to Worse Clinical Outcomes in Chronic Pancreatitis

HCPLive

Compared with non-users, the cannabis use cohort showed significantly greater risks of acute pancreatitis flare pancreatic cancer, and all-cause mortality.

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Intravascular lithotripsy vs. rotational atherectomy on coronary microcirculation: a retrospective multicenter propensity-matched multicenter study

Frontiers in Cardiovascular Medicine

BackgroundCoronary microvascular dysfunction (CMD) predicts poor prognosis in patients with coronary artery disease (CAD). However, the impact of intravascular lithotripsy (IVL) on CMD remains unclear, and no studies have directly compared IVL and rotational atherectomy (RA) in the context of CMD.ObjectiveThis study aimed to evaluate CMD, as indicated by angiographic microvascular resistance (AMR), in patients undergoing IVL- or RA-assisted PCI for heavily calcified coronary lesions.MethodsThis

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ACC Cardio-Obstetrics Member Section Advocates For Legislative Solutions to Improve Maternal Health

American College of Cardiology

Members of ACC's Reproductive Health & Cardio-Obstetrics Member Section met virtually with representatives from 11 congressional offices on May 7 to push for stronger federal action on maternal health.

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Redefining respiratory sinus arrhythmia as respiratory heart rate variability: an international Expert Recommendation for terminological clarity

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 06 May 2025; doi:10.1038/s41569-025-01160-z The physiological phenomenon whereby heart rate varies in phase with breathing in vertebrates has been known as respiratory sinus arrhythmia. In this Expert Recommendation, the authors argue that this terminology is potentially misleading and propose replacing it with the term respiratory heart rate variability, which avoids pathological connotations.

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Managing Mental Health in Patients with IBD, with Sara Horst, MD, MPH

HCPLive

Horst explains the importance of addressing depression and anxiety in patients with IBD and steps clinicians can take to support their patients mental health.

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Marea Makes Progress on MAR001

CardiacWire

Marea Therapeutics presented positive data from the Phase 2a clinical trial of its fat-targeting monoclonal antibody, MAR001, that could help address lipid and metabolic drivers of ASCVD. Originally developed by Novartis, MAR001 targets the ANGPTL4 protein in body fat tissue, which helps it lower remnant cholesterol and triglycerides in the blood. To assess MAR001s impact on remnant cholesterol and triglycerides, researchers randomized 55 patients with hypertriglyceridemia to one of three doses

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OCT-Guided PCI Performs Better Than Angiographic PCI Guidance

American College of Cardiology

The use of optical coherence tomography (OCT) plus predefined algorithmic management achieved better stent implantation results than angiographic guidance when performing PCI in patients with calcified lesions.

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Latin Heart Rounds Series: Current Outcomes of the Norwood Operation

Society of Thoracic Surgeons - Adult Cardiac

Webinar Latin Heart Rounds Series: Current Outcomes of the Norwood Operation gmckinney Wed, 05/07/2025 - 15:05 May 30, 2025 During this webinar, a panel of top surgeons and pediatric cardiologists will review current outcomes of the challenging Norwood operation, including cases found in the STS National Database. Topics will include: Patient selection Surgical primary palliation vs. hybrid approach with both surgical bands and more recent pulmonary flow restrictors Technical aspects of surgical

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MAR001 Cuts Remnant Cholesterol, Triglycerides by 50% in Phase 2a Trial

HCPLive

MAR001 significantly lowers remnant cholesterol and triglycerides in Phase 2a data, offering hope for high-risk cardiovascular patients.

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'Doubly Protected' Carotid Stenting Makes Stroke Less of a Risk

Med Page Today

(MedPage Today) -- WASHINGTON -- The Neuroguard carotid stent system, with its integrated embolic filter, continued to show good results at 2 years for people with carotid artery stenosis deemed poor candidates for surgery, based on the PERFORMANCE.

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Smart Science, Real Solutions: ACC Asia 2025 Tackles Heart Health Challenges Across Asia

American College of Cardiology

The ACC and Singapore Cardiac Society (SCS) are in Singapore for the ACC Asia 2025 Together With SCS 36th Annual Scientific Meeting, bringing together leading experts and cardiovascular clinicians from across Asia to examine emerging trends and evidence-based strategies in the prevention and management of patients with heart disease.

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Cholesterol pill helps those at high risk of heart attack and stroke: Study

Medical Xpress - Cardiology

A Monash-led international study has found a cholesterol-lowering drug may offer a more effective and convenient way to protect people at high risk of heart attack and stroke.

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Despite Guideline Update, Universal HBV Screening Uptake Remains Suboptimal

HCPLive

Najy Issa, MD, describes underwhelming universal HBV screening uptake since 2023 CDC guidelines were implemented and steps to get more patients screened.

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Pathophysiology and clinical use of agents with vasodilator properties in acute heart failure. A scientific statement of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

European Journal of Heart Failure

Vasodilators in acute heart failure: disconnection between beneficial pathophysiological and haemodynamic effects and clinical effects in randomized clinical trials. AHF, acute heart failure; ASCEND-AHF, A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure; BLAST-AHF, Biased Ligand of the Angiotensin receptor STudy in Acute Heart Failure; ED, emergency department; ELISABETH, Effect of an Emergency Department Care Bundle on 30-Day Hospital Discharge a

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ACCEL Lite: WARRIOR Trial: Outcomes to Reduce Events in Non-Obstructive Coronary Artery Disease

American College of Cardiology

Funded by the Congressionally Directed Medical Research Programs (CDMRP) of the Department of Defense, the WARRIOR (Women's IschemiA TRial to Reduce events In non-ObstRuctive CAD) Trial addresses the urgent need for evidence-based care in a growing population of patientsparticularly womenexperiencing ischemia without obstructive coronary artery disease (INOCA).

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Heart rhythm disorder traced to bacterium lurking in gums

Medical Xpress - Cardiology

Tempted to skip the floss? Your heart might thank you if you don't. A new study from Hiroshima University (HU) finds that the gum disease bacterium Porphyromonas gingivalis (P. gingivalis) can slip into the bloodstream and infiltrate the heart. There, it quietly drives scar tissue buildupknown as fibrosisdistorting the heart's architecture, interfering with electrical signals, and raising the risk of atrial fibrillation (AFib).

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Roflumilast Foam 0.3% for Scalp, Body Psoriasis Effective, Safe for Patients

HCPLive

These phase 3 findings from the ARRECTOR trial, published in JAMA, demonstrate rapid and significant relief from plaque psoriasis with roflumilast foam use.

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Pulse Blog: Confronting the Silent Killer

Cardiometabolic Health Congress

Confronting the Silent Killer: Advancing Hypertension Awareness and Action May is High Blood Pressure Education Month Its time to elevate awareness around hypertensionthe silent killer affecting millions of Americansand in support, were offering a special incentive to attend this years annual Cardiometabolic Health Congress (CMHC) in Boston. This month is National High Blood Pressure Education Month the perfect opportunity for healthcare professionals to intensify efforts in combating hypertens

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Is Aficamten Plus Disopyramide More Effective Than Aficamten Alone in oHCM?

American College of Cardiology

The addition of aficamten to disopyramide was effective and well-tolerated in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) with persistent left ventricular overflow tract (LVOT) obstruction, and the withdrawal of disopyramide did not reduce the effectiveness of aficamten.