Heart BMJ

APRIL 10, 2025

Since the first implementation in 2002 by Alain Cribier, transcatheter aortic valve replacement (TAVR) has become a standard procedure for high-risk and elderly patients with severe aortic valve stenosis. Recently, the use of TAVR has expanded to relatively younger patients with low to moderate surgical risk. Infective endocarditis (IE) after TAVR, first reported in medical literature in 2010, is a relatively new and extremely concerning complication. 1 Its incidence, reported as 1.1% per person

Aortic valve 102

Aortic valve Aortic TAVR Stenosis 102

Circulation

APRIL 10, 2025

Circulation, Ahead of Print. The Physical Activity Guidelines for Americans supports sitting less and moving more. Growing evidence suggests that a waking behavior profile with less sedentary behavior and more light-intensity physical activity is associated with more favorable cardiovascular health. Remarkably, little is known about how these behaviors relate to cardiovascular health during pregnancy.

Blood Pressure 83

Blood Pressure Cardiovascular Disease Outcomes Hypertension 83

Nature Reviews - Cardiology

APRIL 6, 2025

Nature Reviews Cardiology, Published online: 07 April 2025; doi:10.1038/s41569-025-01145-y To regenerate the injured heart, cardiomyocytes must proliferate to replace lost myocardial tissue, but this capacity is largely absent in adult mammals. In this Review, Koopmans and van Rooij explore the key pathways that drive cardiomyocyte maturation after birth and how targeted manipulation might reactivate the cell cycle in adult cardiomyocytes.

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Science Daily - Heart Disease

APRIL 8, 2025

New research has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes -- not the presence of certain fats, but their suppression. The study challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels causing inflammation and health risks. Instead, their findings reveal that when ceramides decrease in endothelial cells lining blood vessels, it can be damaging and cause chronic illnesses.

Obesity 66

Obesity Cardiovascular Disease Diabetes Research 66

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

Dr. Paddy Barrett

APRIL 11, 2025

More than heart disease or cancer, dementia is the primary concern for many of the patients I see. Heart disease and cancer attack your body, but dementia attacks your mind and identity. It strips away the fabric of who a person is. That is why I believe people fear dementia so much. Thankfully, 45% of all dementia is preventable 1. Many factors make up that 45%, but one factor seems to impact the risk of dementia the most.

Dementia 76

Dementia Exercise Cancer Heart Disease 76

Circulation

APRIL 7, 2025

Circulation, Ahead of Print. Populations most affected by cardiovascular health disparities, including underrepresented populations with lower socioeconomic status, people with disabilities, and those living in underserved rural communities, are disproportionately exposed to adverse social determinants of health. Specifically, economic instability and suboptimal living conditions within the neighborhood and built environment directly determine access to resources and opportunities for healthful

Technology 79

Technology Health Disparities Cardiovascular Disease Circulation 79

CardiacWire

APRIL 9, 2025

Casting doubt on value based cardiac care, a JAMA study found that outpatient cardiology practices enrolled in an accountable care organization (ACO) through the Medicare Shared Savings Program (MSSP) dont offer better care than non-ACO practices. MSSP was introduced in 2012 to improve care quality and lower Medicare costs by having ACOs assume responsibility for Medicare beneficiaries costs and care quality.

Medicare 59

Medicare Outpatient Coronary Artery Disease AFIB 59

DAIC

APRIL 7, 2025

tim.hodson Mon, 04/07/2025 - 16:15 April 4, 2025 Viz.ai has been named an Award Winner in the 2025 Edison Awards, for the third year in a row. Viz HCM, the companys AI software solution designed to detect and triage patients with signs of hypertrophic cardiomyopathy (HCM), was recognized in the Health Medical & Biotech category and Cardiovascular Health Diagnostics and Monitoring subcategory.

Academic 52

Academic Innovation Cardiomyopathy Electrocardiogram 52

Frontiers in Cardiovascular Medicine

APRIL 10, 2025

ObjectiveTo compare the image quality, radiation dose, and examination time between non-electrocardiogram (ECG)-gated coronary CT angiography (ECG-less CCTA) and conventional ECG-gated CCTA using wide-detector CT, and validate its clinical applicability.MethodsIn this prospective study, 109 patients with suspected coronary artery disease were divided into ECG-less (Group A, n=59) and ECG-gated (Group B, n=50) groups.

Coronary Artery Disease 52

Coronary Artery Disease Plaque Electrocardiogram Stenosis 52

Heart BMJ

APRIL 10, 2025

Background Heart failure (HF) guidelines recommend routine testing for iron deficiency (ID) and, for those with ID, intravenous iron if the left ventricular ejection fraction is <50%. Guideline adherence to these recommendations by cardiologists in China is unknown. Methods and results An independent academic web-based survey was designed and distributed via social networks to cardiologists across China.

Heart Failure 59

Heart Failure Academic Education 59

CardiacWire

APRIL 5, 2025

Expanding the potential patient population for pulsed field ablation, results from the SINGLE SHOT CHAMPION study suggest PFA might be just as good as cryoballoon ablation for patients with paroxysmal AFib. Paroxysmal atrial fibrillation is a type of AFib that causes short, intermittent episodes of irregular and rapid heartbeats originating in the atria.

AFIB 59

AFIB Ablation Atrial Fibrillation Pulmonary 59

Med Page Today

APRIL 7, 2025

(MedPage Today) -- SAN DIEGO -- New data explored the potential beneficial impact that glucagon-like peptide-1 (GLP-1) receptor agonists may have on neurodegenerative diseases. In a plenary session at the annual American Academy of Neurology.

Dementia 133

Dementia 133

Frontiers in Cardiovascular Medicine

APRIL 7, 2025

With the global impact of cardiovascular disease, there is a dire need to understand the mechanisms in the heart during injury and stress. It has been shown that the regulation of the extracellular matrix via cardiac fibroblasts plays a major role in the progression of heart failure and worsening function of the heart. Importantly, it has been suggested that crosstalk between other cardiac cells like cardiomyocytes, immune cells, and endothelial cells are influenced by the pathological function

Cardiovascular Disease 52

Cardiovascular Disease Heart Failure Research Outcomes 52

Open Heart

APRIL 5, 2025

Objective Pulsed-field ablation (PFA) is a new technology of catheter ablation for atrial fibrillation (AF). This research is to investigate the feasibility of a new strategy (transoesophageal echocardiography-guided pulsed field ablation, TEEP) to guide PFA for AF with no contrast and zero fluoroscopy. Methods Patients with AF underwent TEEP under general anaesthesia with the guidance of three-dimensional (3D) transoesophageal echocardiography (TEE) throughout the procedure.

Atrial Fibrillation 52

Atrial Fibrillation Ablation Pulmonary Technology 52

Heart BMJ

APRIL 10, 2025

‘Real knowledge is to know the extent of one’s ignorance ’ Confucius This editorial refers to ‘Gaps in knowledge and management of iron deficiency in heart failure: a nationwide survey of cardiologists in China’, by Su et al. 1 Over the last 25 years, an accumulation of data has highlighted the prevalence of iron deficiency and the value of its correction in patients with heart failure and reduced (HFrEF) or mildly reduced ejection fraction (HFmrEF).

Heart Failure 52

Heart Failure Quality of Life 52

Med Page Today

APRIL 8, 2025

(MedPage Today) -- As measles continues to spread through vulnerable communities in the U.S., HHS Secretary Robert F. Kennedy Jr. has suggested that there are long-term health benefits to contracting the virus, despite decades of data that suggest.

Heart Disease 122

Heart Disease Cancer 122

Frontiers in Cardiovascular Medicine

APRIL 11, 2025

Unlike mammals, zebrafish can regenerate their heart after cardiac insult. There are several ways to perform cardiac injury in zebrafish, but cryoinjury most closely resembles human myocardial infarction (MI). Studies demonstrated that macrophages are essential cells from the beginning to later stages of cardiac injury throughout the regenerative process in zebrafish.

Myocardial Infarction 52

Myocardial Infarction 52

DAIC

APRIL 9, 2025

tim.hodson Wed, 04/09/2025 - 14:38 April 9, 2025 Idorsia Ltd recently announced that the US Food & Drug Administration (FDA), after having released Tryvio from its REMS (Risk Evaluation and Mitigation Strategy) requirement ( announced March 17, 2025 ), has now approved the updated label for Tryvio(aprocitentan). Tryvio is Idorsias dual endothelin receptor antagonist (ERA) indicated for the treatment of systemic hypertension in combination with other antihypertensives to lower blood pressure in

Blood Pressure 52

Blood Pressure Hypertension Myocardial Infarction Kidney Disease 52

Open Heart

APRIL 8, 2025

Objective To validate the prognostic utility of peak creatine kinase-myocardial band isoenzyme (CK-MB) level, left ventricular posterior wall diameter (LVPWD), and a score model for successful weaning from mechanical circulatory support (MCS) in fulminant myocarditis (FM). Furthermore, the severity of the histological data was stratified, and its relationship with the clinical findings was investigated.

Outcomes 52

Outcomes 52

Med Page Today

APRIL 7, 2025

(MedPage Today) -- Comorbidities in midlife were associated with a modestly higher risk of cancer overall and more strongly associated with a risk for multiple individual cancer types, according to a secondary analysis of the prospective Prostate.

Cancer 122

Cancer 122

Frontiers in Cardiovascular Medicine

APRIL 7, 2025

ObjectiveAdvanced glycation end-products (AGEs) may contribute to the pathogenesis of atherosclerotic cardiovascular disease (ASCVD), potentially influencing its development and progression differently at various life stages. This study aimed to elucidate the associations between AGEs and the risk of ASCVD across different age groups.MethodsIn this cross-sectional study, 1,240 subjects were enrolled and divided into three groups (Group , 2039 years old, n=468; Group , 4059 years old, n=471; Grou

Risk Factors 52

Risk Factors Cardiovascular Disease Research 52

HCPLive

APRIL 5, 2025

The Best Practice Advice is aimed at detailing benefits and harms of cannabis or cannabinoids in the management of chronic noncancer pain.

Best Practices 119

Best Practices 119

Heart Sisters

APRIL 6, 2025

"Our medical language is filled with negativity and dehumanization." Dr. Colleen Christmas, Johns Hopkins University School of Medicine. Why doctors need to stop using words that hurt patients.

Heart Failure 118

Heart Failure 118

DAIC

APRIL 8, 2025

Prof. David Luria (left), Director of Electrophysiology at Hadassah Medical Center, and Ziv Menshes (right), CEO of CardioVia tim.hodson Tue, 04/08/2025 - 14:38 April 7, 2025 CardioVia, a medical device company specializing in advanced cardiac care solutions, has received U.S. Food and Drug Administration (FDA) clearance for its ViaOne system. This device is designed to enable safe and precise access to the hearts surface (pericardial space) for both diagnostic and therapeutic interventions wi

Electrophysiology 52

Electrophysiology Arrhythmia Innovation Technology 52

Frontiers in Cardiovascular Medicine

APRIL 7, 2025

Cardio-kidney metabolic (CKM) syndrome represents a complex and circular interplay of cardiovascular, renal, and metabolic dysfunctions, significantly contributing to global morbidity and mortality. This expert opinion synthesizes insights from a panel of Italian specialists in cardiology, nephrology, and diabetology, advocating for a holistic and integrated framework for CKM management.

Quality of Life 52

Quality of Life Innovation Outcomes 52

International Journal of Cardiovascular Sciences

APRIL 8, 2025

The International Journal of Cardiovascular Sciences (IJCS) is seeking a volunteer Assistant Editor to support the Editor-in-Chief in the journal’s editorial activities. This is an excellent opportunity for early-career individuals in the cardiovascular health field who wish to develop editorial skills and contribute to the advancement of science in this area, as well as engage in the journals outreach activities.

Article 52

Article Certification Academic Document 52

Med Page Today

APRIL 7, 2025

(MedPage Today) -- People taking medications for attention deficit-hyperactivity disorder (ADHD) showed small changes to their cardiovascular metrics -- and it wasn't just the stimulants to watch out for, a systematic review suggested. Based.

Blood Pressure 111

Blood Pressure 111

HCPLive

APRIL 10, 2025

Laine gave an overview of the ACP Internal Medicines Friday Plenary session and how it reflects top-of-mind topics for IM clinicians.

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Frontiers in Cardiovascular Medicine

APRIL 6, 2025

Arteria lusoria (AL), an anomaly of the right subclavian artery, occurs in 2% of individuals and can cause symptoms such as dysphagia due to its retroesophageal course. Often associated with Kommerell's diverticulum (KD), a dilation at the artery's origin, this condition poses risks of rupture or dissection. Symptomatic cases and aneurysms necessitate surgical intervention, while asymptomatic cases may warrant observation.

Aneurysm 52

Aneurysm Anatomy Outcomes 52

Medical Xpress - Cardiology

APRIL 7, 2025

Most people have right-dominant heartswhich to a doctor or a researcher means they have an artery that extends from the right side of their hearts to supply oxygenated blood to the back side. For some people, this artery, called the posterior descending artery, comes from the left side or from both directions. A study has found that the gene CXCL12 is connected to this artery's formation and that its directional pattern is set very early in human development.

Research 109

Research 109

American Heart News - Heart News

APRIL 7, 2025

Statement Highlights: Mobile health technologies, such as wearable devices, mobile health apps and telehealth or remote coaching, have shown potential to help people start and maintain heart-healthy behaviors, such as eating a healthy diet, increasing.

Technology 106

Technology Diet 106

HCPLive

APRIL 6, 2025

The study evaluated more than 450 patient visits and concluded AI decision support could improve adherence to guideline-adherent care recommendations.

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Stroke Journal

APRIL 8, 2025

Stroke, Ahead of Print. BACKGROUND:The National Institutes of Health Stroke Scale is used globally to rate neurological deficits in patients with acute stroke. Originally designed for research use, the scale uses idiosyncratic scoring rules and requires thorough training for proper use. Currently available training and certification systems are timeworn and limited in the range of demonstrated neurological findings.

Certification 40

Certification Stroke Strokes Research 40

Hypertension Journal

APRIL 11, 2025

Hypertension, Ahead of Print. BACKGROUND:Aberrant BMPR2 (bone morphogenetic protein receptor 2) signaling is associated with the pathogenesis of pulmonary hypertension. SMAD4 is an essential downstream effector of BMPR2 signaling, but whether and how it participates in pulmonary hypertension are unclear.METHODS:Globally and vascular cell-specifically inducible knockout mouse models were used to examine the role of SMAD4 deficiency in differential cell compartments in the development of pulmonary

Pulmonary 40

Pulmonary Hypertension Aneurysm Aortic 40

Cardiovascular Diabetology

APRIL 8, 2025

The global prevalence of diabetes is rapidly increasing, significantly raising the risk of various cardiovascular diseases. Among these, diabetic cardiomyopathy (DCM) is a distinct and critical complication ch.

Cardiomyopathy 100

Cardiomyopathy Diabetes Exercise Cardiovascular Disease 100

HCPLive

APRIL 10, 2025

Tailor discusses the future of AI in ophthalmology and beyond, and some of the challenges it may bring.

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