Sat.Aug 31, 2024 - Fri.Sep 06, 2024

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Presidential Candidates Should Undergo Standardized Cognitive and Physical Testing

Med Page Today

(MedPage Today) -- Health professionals often perform the "eyeball test" when they first meet a patient. Through the power of observation, pixels of information are gathered quickly and often unconsciously to determine whether a patient is unwell.

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20 hospitals with highest, lowest heart failure death rates

Becker's Hospital Review - Cardiology

Chicago-based Northwestern Memorial Hospital and VA Boston Healthcare System-Jamaica Plain (Mass.) have the lowest death rate for heart failure patients in the country, according to CMS data.

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GLP-1R–positive neurons in the lateral septum mediate the anorectic and weight-lowering effects of liraglutide in mice

Journal of Clinical Investigation - Cardiology

Liraglutide, a glucagon-like peptide-1 (GLP-1) analog, is approved for obesity treatment, but the specific neuronal sites that contribute to its therapeutic effects remain elusive. Here, we show that GLP-1 receptor–positive (GLP-1R–positive) neurons in the lateral septum (LSGLP-1R) play a critical role in mediating the anorectic and weight-loss effects of liraglutide.

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Wearable heart monitor increases diagnosis of irregular heart rhythm

Science Daily - Stroke

Wearable, long-term continuous heart monitors helped identify 52% more cases of atrial fibrillation compared to usual care, but that did not lead to a reduction in hospitalizations due to stroke, according to a new study.

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Up to 1 in 5 Dementia Cases May Be Attributable to Vision Impairment

Med Page Today

(MedPage Today) -- Up to one in five prevalent dementia cases may be attributable to impaired vision, a cross-sectional analysis suggested. In a study of nearly 2,800 older Americans, the population attributable fraction (PAF) of prevalent dementia.

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Reagan Udall Foundation for FDA Facilitates Discussion on Urgent Needs in PTSD Therapy

HCPLive

The Reagan Udall Foundation hosted a meeting on PTSD treatment needs, with experts and stakeholders highlighting gaps and potential therapies, including MDMA-assisted therapy.

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Research shows regular mobile phone is associated with increased risk of cardiovascular diseases

Medical Xpress - Cardiology

A new study has found that regular mobile phone use was positively associated with incident cardiovascular disease risk, especially in current smokers and individuals with diabetes. In addition, this association was partly attributed to poor sleep, psychological distress, and neuroticism.

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Study estimates home blood pressure devices don't fit properly for more than 17 million US adults

Science Daily - Heart Disease

Over-the-counter blood pressure measuring devices offer a simple, affordable way for people to track hypertension at home, but the standard arm-size ranges for these devices won't appropriately fit millions of U.S. consumers, according to a new study.

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European Commission Revokes Obeticholic Acid (Ocaliva) CMA for Primary Biliary Cholangitis

HCPLive

The decision to revoke the conditional marketing authorization is based on a June 2024 CHMP recommendation from the EMA suggesting the benefits of Ocaliva do not outweigh its risks.

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Why the sudden shock after a few days of malaise?

Dr. Smith's ECG Blog

Written by Magnus Nossen - Edits by Grauer and Smith The patient in today’s case is a woman in her 70s with a previous medical history of HTN and hyperlipidemia. She presented to an outside hospital after several days of malaise and feeling unwell. At the time of admission, her vital signs were normal. Heart rate was in the 80s. She had a very elevated troponin T at 12,335 ng/L at the time of presentation. ( This is a value typical for a large subacute MI, n ormal value 48 hours after myocardial

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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Clinical trial finds finerenone reduces worsening heart failure and cardiovascular death

Science Daily - Heart Disease

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial.

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Afib Ablation Delivers in First Sham-Controlled Study

Med Page Today

(MedPage Today) -- LONDON -- Pulmonary vein isolation (PVI) produced real short-term improvements for people with atrial fibrillation (Afib or AF), according to the first sham-controlled trial on the subject. Continuous monitoring by implantable.

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Study Unlocks Key Bacteria That Explains Why Only Some with IBD Respond to Thiamine

HCPLive

A new study discovers patients with IBD who respond well to high-dose thiamine treatment have an abundance of faecalibacterium prausnitzii.

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Remote monitoring and pharmacist helped improve hard-to-control blood pressure

American Heart News - Heart News

Research Highlights: A new study finds that up to 74% of participants with resistant or difficult-to-control high blood pressure, including those with chronic kidney disease, were able to improve control of their blood pressure within 12 months after.

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Pregnancy-related heart failure is under-detected; AI-enabled stethoscope helped doctors diagnose twice as many cases

Science Daily - Heart Disease

Heart failure during pregnancy is a dangerous and often under-detected condition because common symptoms -- shortness of breath, extreme fatigue and trouble breathing while lying down -- are easily mistaken for typical pregnancy discomforts. A new study showed an artificial intelligence (AI)-enabled digital stethoscope helped doctors identify twice as many cases of heart failure compared to a control group that received usual obstetric care and screening.

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Brain Aging Trajectories Identified in Post-Mortem Tissue

Med Page Today

(MedPage Today) -- Two trajectories of brain aging were identified in a cellular analysis of post-mortem brain tissue: one leading to Alzheimer's disease, the other to an alternative brain aging pathway. The study involved participants in the.

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Dana Rizk, MD: “Very Exciting” Pipeline Developments in IgA Nephropathy

HCPLive

Rizk discusses the recent FDA accelerated approval of iptacopan (Fabhalta) and reflects on the significance of other therapeutic developments in IgAN.

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High blood pressure a concern for adolescents and young adults in U.S.

American Heart News - Heart News

Research Highlights: In the first study, nearly 23% of young adults (ages 18-39 years) included in the NHANES 2017-2020 datasets had high blood pressure (130/80 mm Hg or greater). In addition, they were more likely to self-report being uninsured, food.

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Regular mobile phone use may increase the risk of cardiovascular diseases, study suggests

Science Daily - Heart Disease

A new study has found that regular mobile phone use was positively associated with incident cardiovascular diseases risk. In addition, this association was partly attributed to poor sleep, psychological distress, and neuroticism.

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Cancer therapy–related salivary dysfunction

Journal of Clinical Investigation - Cardiology

Salivary gland dysfunction is a common side effect of cancer treatments. Salivary function plays key roles in critical daily activities. Consequently, changes in salivary function can profoundly impair quality of life for cancer patients. We discuss salivary gland anatomy and physiology to understand how anticancer therapies such as chemotherapy, bone marrow transplantation, immunotherapy, and radiation therapy impair salivary function.

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The Widowmaker: Clarifying the Record for Our Patients

Med Page Today

(MedPage Today) -- I'm a retired doctor who walks about 8 miles on some rural roads each morning. People sometimes stop to ask me medical questions. Some call me, "The Street Doctor." Last week, a 72-year-old man stopped to tell me about his heart.

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Lessons learnt from HF coding in primary care. What might best practice look like?

The British Journal of Cardiology

Heart failure (HF) is a prevalent and complex condition that demands precise and efficient management. This paper delves into a critical, yet often under-recognised, challenge in HF care – the accurate coding of patients on HF registers. We explore how discrepancies in coding, including missing patients and incorrect HF type classifications, can significantly impact patient management.

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Analysis found weight-loss surgery may help people with obesity manage high blood pressure

American Heart News - Heart News

Research Highlights: In an analysis of 18 randomized clinical trials, people with obesity and high blood pressure who underwent bariatric (weight-loss) surgery were almost three times more likely to achieve blood pressure remission, defined as.

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Study looks deeper into olive oil's health benefits

Medical Xpress - Cardiology

Olive oil has long been touted for its ability to lower heart disease risk. So University of Florida researchers set out to dig deeper to learn how much olive oil is beneficial.

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Women's 30-Year Heart Risk Can Be Predicted by Just Three Factors

Med Page Today

(MedPage Today) -- LONDON -- A combination of three factors -- high-sensitivity C-reactive protein (hsCRP), LDL cholesterol, and lipoprotein(a), or lp(a) -- independently predicted cardiovascular disease over 30 years in women who were initially.

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Researchers discover new insights into the neurobiological origins of ataxia

Science Daily - Stroke

A study investigated the origin of ataxia in the brain of patients with stroke. A significant number of the stroke lesions in the patients were located outside the cerebellum.

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Popular home blood pressure monitoring cuff devices may not fit some US adults

American Heart News - Heart News

Research Highlights: An analysis of at-home blood-pressure monitors estimates that the arm cuffs for 10 of the most popular potentially do not fit up to 18 million adults in the U.S. and nearly 12% of Black adults. To ensure accurate blood pressure.

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You Don't Want Money. You Want Time.

Dr. Paddy Barrett

If you spend long enough thinking about health, you will come to a singular realisation: Regardless of how long you live or how good your physical or cognitive capabilities are, how you spend your time will have the biggest impact on the quality of your life. This is the domain of soul span. Soul span is about how you optimise for meaning and purpose in your life.

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Stenting, TAVR Make Sense Packaged Together for Some Patients

Med Page Today

(MedPage Today) -- LONDON -- Some individuals already undergoing transcatheter aortic valve replacement (TAVR, also TAVI) might as well get coronary lesions revascularized around the same time, according to the NOTION-3 randomized trial. Clinical.

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Thomas A. Wadden, PhD: Semaglutide Not Linked to Increased Depression Risk

HCPLive

In an interview with HCPLive, Wadden discussed the findings of a post-hoc analysis, supporting how semaglutide is not linked to an increased suicidal ideation risk.

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Novel point-of-care heart attack test leads to shorter emergency department stays for some patients

Medical Xpress - Cardiology

A new, rapid blood test that spots whether people are having a heart attack could improve the treatment of people presenting with chest pain at emergency departments, according to late-breaking research presented in a Hot Line Session Sept. 2 at this year's ESC Congress 2024.

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High cholesterol levels at a young age significant risk factor for atherosclerosis

Science Daily - Heart Disease

Our risk of developing atherosclerosis -- 'furring' of the arteries -- can begin much earlier in life than was previously thought, highlighting the need to keep cholesterol levels low even when we are young, new research has discovered.

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Potassium Strategy After Cardiac Bypass Grafting Doesn't Impact Afib Risk

Med Page Today

(MedPage Today) -- LONDON -- Keeping potassium levels high after cardiac surgery in hopes of preventing post-surgical atrial fibrillation (Afib) didn't work, a randomized clinical trial showed. New-onset Afib after isolated coronary artery bypass.

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FDA Approves Travere Therapuetics’ Sparsentan for Proteinuria Reduction in Adult Primary IgAN

HCPLive

The FDA has granted full approval to sparsentan (Filspari) for reducing proteinuria in adults with IgAN at risk of rapid disease progression based on PROTECT trial data.

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Dedicated trial in women demonstrates the superiority of transcatheter vs. surgical aortic valve replacement

Medical Xpress - Cardiology

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis Risk

The New England Journal of Medicine

In this phase 3 trial involving patients with persistant chylomicronemia, plozasiran, a short interfering RNA that targets APOC3, reduced triglyceride levels and the incidence of pancreatitis.

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