Dr. Smith's ECG Blog

NOVEMBER 27, 2024

Pendell and I and the geniuses at Powerful Medical (Producers of the PMCardio Queen of Hearts OMI AI app ) are working on an objective, mathematical definition of hyperacute T-waves , based on real OMI outcomes and hyperacute T-wave annotation that has excellent interrater agreement (between me and Pendell), and it will end up being a logistic regression using these 3 variables: 1) area under the curve (AUC) relative to the QRS size 2) increased symmetry , as defined by time from T-wave onset to

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Medical Xpress - Cardiology

NOVEMBER 14, 2024

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns. Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens.

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Cholesterol Cardiovascular Disease Heart Attack Heart attacks 128

Physiologically Speaking

NOVEMBER 22, 2024

Greetings! Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including FSTFUEL electrolytes, Examine.com , and my book “VO2 Max Essentials ” can be found at the end of the post. Physiologically Speaking is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.

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Physiology Dementia Genetic predisposition Exercise 110

Science Daily - Heart Disease

NOVEMBER 18, 2024

A study testing a new nasal spray form of the medication bumetanide, a commonly prescribed diuretic, was found to be as safe and well-tolerated (meaning with no significant nasal irritation) in healthy adults in comparison to the oral and intravenous forms of the medication. The existing oral and intravenous forms of bumetanide are commonly prescribed for people with heart failure because they ease tissue swelling, a common cause of symptoms for people with heart failure.

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Heart Failure 107

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

Patient Care

DAIC

NOVEMBER 18, 2024

tim.hodson Mon, 11/18/2024 - 10:55 Nov. 16, 2024 Anthos Therapeutics, Inc.recently presented new data at the American Heart Association (AHA) Scientific Sessions from its AZALEA-TIMI 71 study that demonstrated the novel factor XI inhibitor abelacimab led to consistent and substantial reductions in bleeding for patients on or off antiplatelet (APT) therapy, as compared to rivaroxaban.

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Peripheral Arterial Disease Blood Clot Coronary Artery Disease General Cardiology 98

Dr. Paddy Barrett

NOVEMBER 30, 2024

Aaaaaaaand…… now today is the correct day for this email to go out. Not on Tuesday, as it inadvertently did. Our publishing platform has been letting us down recently with scheduling glitches, so if you have received any duplicate emails - our apologies for that. Just a reminder that you can get access to the Heart Health Formula for 30% off.

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Cholesterol Blood Pressure Heart Disease Coronary Angiogram 89

Medical Xpress - Cardiology

NOVEMBER 21, 2024

After severe heart failure, the ability of the heart to heal by forming new cells is very low. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart. This is according to a new study from Karolinska Institutet published in the journal Circulation.

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Heart Failure Circulation 106

CardiacWire

NOVEMBER 8, 2024

Late-breaking second year results from the PROMISE II trial showed that the LimFlow system achieved strong outcomes for avoiding amputations and promoting limb salvage among “no-option” patients with chronic limb-threatening ischemia (CLTI). The LimFlow system consists of several products designed to optimize blood flow in critically ischemic feet by facilitating revascularization.

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Ischemia Research Diabetes Outcomes 64

Science Daily - Heart Disease

NOVEMBER 26, 2024

You may have heard sleep described as something of a magic pill for the body. With the right amount, timing, and quality, it can work wonders -- strengthen the immune system, improve blood sugar, even decrease the risk of heart attacks and strokes. Sleep differences have been reported for some time in men and women, but it is not well known whether the characteristics of sleep serve different functions in one gender over the other, especially as it relates to the heart.

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Blood Pressure Research Heart Attack Heart attacks 120

Frontiers in Cardiovascular Medicine

NOVEMBER 14, 2024

BackgroundIn recent years, the relationship between periodontal disease (PD) and atherosclerosis (AS) has garnered significant scholarly attention. Chronic inflammation induced by PD may promote the onset and progression of AS through multiple mechanisms. Given the increasing global incidence of both PD and AS, which adversely affects patients’ quality of life and longevity, further investigation into the interplay between PD and AS is of substantial clinical importance.

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Atherosclerosis Quality of Life Research Document 64

Dr. Paddy Barrett

NOVEMBER 12, 2024

Let me tell you a story. At least once a week, one of my friends or someone I know will contact me with the same question: “I am getting to that age where heart disease is a possibility. What do I need to do?” After getting tired of writing long emails, I started thinking I should put together a presentation they could watch. This would at least prevent me from going over the same topic over and over again.

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Heart Disease 96

ADN Center of Excellence

NOVEMBER 14, 2024

For medical professionals, the path to excellence is one of continuous learning and skill enhancement. Fellowships represent a vital opportunity to bridge the gap between general practice and advanced specialization. Whether you are at the crossroads of choosing your career focus or seeking to refine your expertise, a fellowship could be the game-changing step you need.

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Academic Interventional Cardiology Private Practice Innovation 59

Medical Xpress - Cardiology

NOVEMBER 14, 2024

A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, β-conglycinin (β-CG), which can support heart health by influencing gut bacteria. Their analysis revealed that the soybean protein rich diet increased the production of the short-chain fatty acids (SCFAs) in the intestine that play a role in protecting the heart.

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Heart Failure Diet Research 112

CardiacWire

NOVEMBER 13, 2024

Troubling results from the SAFE-IVC study revealed that just one in six patients gets their inferior vena cava filters removed, despite clear guidelines calling for IVC filter removal as early as possible. An IVC filter is a small device that helps stop blood clots from going up into the lungs and is usually surgically inserted. IVC filters are used to prevent pulmonary embolism in patients with venous thromboembolism and can’t receive anticoagulation treatment.

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Blood Clot Thrombosis Embolism Medicare 59

Science Daily - Heart Disease

NOVEMBER 11, 2024

Fear of another heart attack was a significant ongoing contributor to how heart attack survivors perceive their health, according to a study. While anxiety and depression are recognized as common conditions after a heart attack, they did not explain the impact of fear of recurrence in this study. The researchers suggest that fear of another heart attack should be evaluated and addressed separately from depression and anxiety.

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Heart Attack Heart attacks Research 103

Frontiers in Cardiovascular Medicine

NOVEMBER 21, 2024

BackgroundIt's recognized that stress hyperglycemia ratio (SHR) is considered a significant indicator of poor prognosis in many diseases. However, its role in critically ill patients with acute heart failure (acute HF) remains underexplored.MethodsWe conducted a retrospective cohort study on patients with acute HF included in the Medical Information Mart for Intensive Care IV (MIMIC-IV) version 2.2 database.

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Heart Failure Research 59

MIBHS

NOVEMBER 15, 2024

Undergoing heart surgery can be a life-changing experience, especially for those with coronary artery disease or other heart conditions. Minimally invasive or bloodless heart surgery techniques have made recovery more manageable and less daunting. However, as patients emerge from this journey, many are eager to return to their normal activities, including running.

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Cardiac Rehabilitation Exercise Chest Pain Diet 52

ADN Center of Excellence

NOVEMBER 7, 2024

The journey from a freshly minted medical graduate to a skilled specialist involves years of dedication, hard work, and targeted training. Among the pivotal steps in this journey, fellowship programs play an essential role in helping doctors gain hands-on experience, deepen their expertise, and establish a career path in highly specialized fields. At ADN CoE, we are dedicated to providing top-tier fellowship programs in various specialties, enabling medical professionals to excel in their chosen

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Cancer Academic Research Interventional Cardiology 59

Heart BMJ

NOVEMBER 25, 2024

Cardiac rehabilitation (CR) is a multidisciplinary supervised programme which typically consists of tailored exercise and education on lifestyle management and risk factor modification in cardiac patients. Participation in CR reduces morbidity and mortality, while improving quality of life following major cardiovascular events. Despite the benefits of CR, it is underutilised, generally in the 20%–30% range for eligible patients.

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Cardiac Rehabilitation Quality of Life Exercise Education 52

DAIC

NOVEMBER 19, 2024

tim.hodson Tue, 11/19/2024 - 15:57 Nov. 18, 2024 — Abbott recently announced new data for the Amplatzer Amulet Left Atrial Appendage (LAA) Occluder to treat people with atrial fibrillation (AFib) who are at an increased risk of stroke. The new five-year findings demonstrate that Abbott's Amplatzer Amulet helps more patients avoid long-term use of blood-thinning medication compared to the Watchman device.

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AFIB Stroke Strokes Atrial Fibrillation 52

Medical Xpress - Cardiology

NOVEMBER 20, 2024

Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study in JACC: Basic to Translational Science. The authors say the research should serve as a "cautionary tale" about possible long-term health effects of these drugs.

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Research 143

Frontiers in Cardiovascular Medicine

NOVEMBER 26, 2024

Cardiovascular disease (CVD) is responsible for approximately 30% of annual global mortality rates, yet existing treatments for this condition are considered less than ideal. Despite being previously overlooked, lactate, a byproduct of glycolysis, is now acknowledged for its crucial role in the cellular functions of the cardiovascular system. Recent studies have shown that lactate influences the proliferation, differentiation, and activation of immune cells through its modulation of post-transla

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Cardiovascular Disease Article 59

Nature Reviews - Cardiology

NOVEMBER 17, 2024

Nature Reviews Cardiology, Published online: 18 November 2024; doi:10.1038/s41569-024-01100-3 Cholesterol crystals (CCs) have a pathogenic role in various cardiovascular diseases, particularly atherosclerosis. In this Review, Boisvert and colleagues describe the mechanisms underlying CC formation and the role of CCs in cardiovascular disease, as well as therapeutic approaches aimed at reducing CC-mediated atherosclerotic burden.

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Cholesterol Atherosclerosis Cardiovascular Disease 56

American Heart News - Heart News

NOVEMBER 13, 2024

Statement Highlights: A new scientific statement outlines the role of primary care professionals in helping their patients achieve Life's Essential 8, the key measures for improving and maintaining cardiovascular health defined by the American Heart.

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Becker's Hospital Review - Cardiology

NOVEMBER 11, 2024

Cleveland Clinic, Chesterfield, Mo.-based Mercy and Bentonville, Ark.-based nonprofit organizations the Alice L. Walton Foundation and the Heartland Whole Health Institute have partnered to invest $700 million over 30 years to address the "$950 million lost annually" as patients leave Northwest Arkansas for specialty care, according to a Sept. 24 news release shared by Cleveland Clinic.

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DAIC

NOVEMBER 8, 2024

tim.hodson Fri, 11/08/2024 - 13:23 Nov. 4, 2024 — Royal Philips recently announced enrollment of the first patient in the U.S. THOR IDE clinical trial, which will study an innovative combined laser atherectomy and intravascular lithotripsy catheter that integrates two critical PAD treatments into a single device. Procedures that previously required the use of two different devices can now be performed in a single procedure using a single device, simplifying workflows and procedures and potential

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Innovation Peripheral Arterial Disease Technology Ultrasound 52

GEMMS

NOVEMBER 11, 2024

As the healthcare landscape evolves, many cardiology practices shift from the traditional fee-for-service (FFS) model to value-based care. This transition reflects a growing focus on prioritizing patient outcomes over the volume of services provided. By emphasizing healthcare efficiency and improved outcomes, value-based care is transforming the way cardiology practices deliver patient care, especially when addressing chronic conditions common in cardiac patients.

Technology 59

Technology Patient Care Education Quality of Life 59

Frontiers in Cardiovascular Medicine

NOVEMBER 12, 2024

ObjectiveThis study aimed to investigate the causal relationship between insomnia and the risk of myocardial infarction (MI) and explore potential mediators such as smoking initiation, alcohol consumption and body mass index (BMI) using mendelian randomization (MR) analysis.MethodsData from 1,207,228 individuals of European ancestry were obtained from the UK Biobank and 23andMe for insomnia-related genetic associations.

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Myocardial Infarction BMI 59

American College of Cardiology

NOVEMBER 1, 2024

The Centers for Medicare and Medicaid Services (CMS) released the 2025 Medicare Physician Fee Schedule (PFS) final rule and the 2025 Hospital Outpatient Prospective Payment System (OPPS) and Ambulatory Surgery Center (ASC) final rule on Nov. 1. Of note, the 2025 PFS conversion factor is $32.3465, a reduction of 2.83% from $33.2875 in 2024. Overall, PFS reimbursement for cardiovascular services is projected to remain flat compared with 2024, with changes to policies and individual services roughl

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CMS Medicare Hospital Reimbursement 60

Medical Xpress - Cardiology

NOVEMBER 27, 2024

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier—from their mid 50s to mid 70s—than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

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Cardiovascular Disease Obesity Risk Factors 135

Med Page Today

NOVEMBER 8, 2024

(MedPage Today) -- Healthier lifestyle behaviors in midlife were linked with better outcomes in people with genetic predisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed. Over about 12 years of follow-up.

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Genetic predisposition Dementia Stroke Strokes 136

American Heart News - Heart News

NOVEMBER 11, 2024

Research Highlights: A preliminary study combining a patent-applied, AI-powered algorithm with a high-speed, 5-to 30-second video of skin on the face and the palm of the hand detected if someone had high blood pressure as well as using a blood.

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Blood Pressure Diabetes Research 135

DAIC

NOVEMBER 8, 2024

tim.hodson Fri, 11/08/2024 - 10:10 Medtronic recently announced results from two studies evaluating the utility of atherectomy for peripheral endovascular interventions. Results from both analyses were released at the Vascular InterVentional Advances (VIVA) 2024 conference in Las Vegas. The Total REALITY study retrospectively compared directional atherectomy (DA) versus balloon predilatation prior to drug-coated balloon (DCB) treatment of long, calcified femoropopliteal lesions.

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Stents Stent Angioplasty Peripheral Arterial Disease 52

Frontiers in Cardiovascular Medicine

NOVEMBER 11, 2024

AimTo evaluate the real-life effectiveness and safety of hydrogen inhalation (HI) therapy as an additional treatment in Chinese adults with hypertension.MethodsThis observational, retrospective clinical study included hypertensive patients receiving routine antihypertensives with or without HI initiation from 2018 to 2023. Participants were assigned to the HI group or non-HI group (control group) after propensity score matching.

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Hypertension Blood Pressure Research Outcomes 59

Society of Thoracic Surgeons - Congenital

NOVEMBER 8, 2024

At the 2024 European Association for Cardio-Thoracic Surgery (EACTS) meeting in Lisbon, Portugal, leaders in cardiac surgery and interventional cardiology came together, signaling a newfound harmony over coronary revascularization practices for complex heart conditions. This session marked a significant change from the intense disagreements that followed the EXCEL trial controversy five years ago, which raised concerns about data interpretation in revascularization treatments for left main disea

Interventional Cardiology 52

Interventional Cardiology 52

Medical Xpress - Cardiology

NOVEMBER 27, 2024

An irregular sleep-wake cycle is associated with a heightened risk of major cardiovascular events, such as heart attack and stroke, even for those who clock up the recommended nightly hours of shut-eye, finds research published online in the Journal of Epidemiology & Community Health.

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Heart Attack Heart attacks Research Stroke 133