Ken Grauer, MD
DECEMBER 28, 2024
I was sent the ECG in Figure-1 told only that the patient was an older adult who reported dizziness with activity. QUESTIONS: What is the rhythm? ( HINT: There are at least 4 important findings that should be noted ). Is there AV block? Figure-1: The initial ECG in today's case. ( To improve visualization I've digitized the original ECG using PMcardio ).
Science Daily - Stroke
DECEMBER 18, 2024
Light and moderate consumption of wine is associated with a lower risk of cardiovascular complications, according to a multicenter study. The study is based on the analysis of a biomarker of wine intake -- specifically, tartaric acid, present in grapes. It was carried out in 1,232 participants in the PREDIMED project, a major scientific epidemiological study in nutrition on the effects of the Mediterranean diet on cardiovascular health.
Science Daily - Heart Disease
DECEMBER 2, 2024
Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study. According to the researchers, these risk reductions are likely driven by the replacement of red and processed meats with plant proteins. The researchers also observed that a combination of consuming more plant protein and higher protein intake overall provided the most heart health benefits.
Dr. Smith's ECG Blog
DECEMBER 3, 2024
This was written by one of our fine residents, who will soon be an EMS fellow: Michael Perlmutter Case A mid-50s male came to the ED with a burning sensation that was acutely worse while at home. He had recently returned from overseas travel where these symptoms had been intermittently bothersome over the preceding weeks and had been attributed to heartburn.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Physiologically Speaking
DECEMBER 17, 2024
Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. While CAC is typically associated with traditional risk factors such as age, hypertension, and smoking, paradoxically elevated CAC scores have been observed in male endurance athletes despite their otherwise healthy profiles. This has raised concerns that long-term, high-volume exercise might be detrimental to heart health.
Frontiers in Cardiovascular Medicine
DECEMBER 18, 2024
Extracellular vesicles (EVs) are nanosized particles secreted by cells that play crucial roles in intercellular communication, especially in the context of cardiovascular diseases (CVDs). These vesicles carry complex cargo, including proteins, lipids, and nucleic acids, that reflects the physiological or pathological state of their cells of origin. Multiomics analysis of cell-derived EVs has provided valuable insights into the molecular mechanisms underlying CVDs by identifying specific proteins
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
Heart BMJ
DECEMBER 23, 2024
Extracorporeal shock wave lithotripsy (ESWL) is standard of care for the treatment of renal calculi. Fracturing large renal calculi using acoustic energy allows them to be safely passed as smaller fragments therefore avoiding surgical treatment. The adaption of ESWL to the vascular space, termed intravascular lithotripsy (IVL), could be said to have a similar goal and has sparked renewed interest in the percutaneous treatment of calcified coronary artery disease (CCAD).
ECG Cases
DECEMBER 3, 2024
In this month's ECG Cases Jesse McLaren takes us through 6 cases highlighting important mirror concepts in ECG interpretation including: which leads are reciprocal to each other, how to identify which is the main ST/T change and which is the mirror, reciprocal changes highlighting subtle inferior, lateral and posterior OMI, ST elevation in aVR as a mirror to widespread ST depression and more.
Dr. Smith's ECG Blog
DECEMBER 20, 2024
Written by Willy Frick with edits by Ken Grauer An older man with a history of non-ischemic HFrEF s/p CRT and mild coronary artery disease presented with chest pain. He said he had had three episodes of chest pain that day while urinating. The following ECG was obtained in the emergency department during active chest pain. ECG 1 What do you think? There is a lot going on in this ECG.
Heart Sisters
DECEMBER 8, 2024
"When Connie Jorsvik was a cardiac nurse, it always seemed like more women than men were admitted to her hospital after Christmas. Many of these women had been experiencing cardiac symptoms for days - and even weeks. Women tend to put off seeking treatment because we so often put ourselves last on our priority list - and there is no bigger time for everyone else's priorities than the holidays!
HeartRhythm
DECEMBER 31, 2024
Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute Myocardial Infarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardial infarction (MI) has changed over time. Patients recruited to these trials had left ventricular ejection fraction (LVEF) <40% following acute MI.
Circulation
DECEMBER 3, 2024
Circulation, Ahead of Print. Smokeless oral nicotine products are addictive, and their use has potential adverse effects on some but not all biomarkers of cardiovascular risk. The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovascular disease. Similarly, smokeless tobacco has the potential to increase the risk of oral cancer, but the risks depend on the chemical composition of the product.
DAIC
DECEMBER 3, 2024
tim.hodson Tue, 12/03/2024 - 16:52 Nov. 18, 2024 — In November, Esperion presented an analysis from the CLEAR Outcomes study focused on patients with Peripheral Artery Disease (PAD) who were unable or unwilling to take statin medications. These data were presented at the 2024 American Heart Association Scientific Sessions, in Chicago, IL. Additionally, two exploratory analyses from the CLEAR Outcomes trial and a real-world analysis of bempedoic acid usage were presented at the conference.
ECG Cases
DECEMBER 3, 2024
On this month's EM Quick Hits podcast: Ross Prager on TEE in cardiac arrest, Justin Morgenstern on nebulized ketamine for analgesia in the ED, Hans Rosenberg & Krishin Yadav on standardizing cellulitis management, Mathew McArther on latest studies on subcutaneous insulin protocols in DKA, Jennifer C. Tang on documenting differential diagnoses medicolegal tips.
Dr. Smith's ECG Blog
DECEMBER 16, 2024
Which patient needs a CT Scan? Case 1: 20-something woman with chest pain Case 2: 50-something man with chest pain Case 1 A 20-something yo woman presented in the middle of the night with severe crushing chest pain. It had begun 4 hours before arrival and was initially dull, but became severe and "unbearable" 2 hours prior to arrival. She was a walk-in at triage.
European Journal of Heart Failure
DECEMBER 19, 2024
Summary of the key background and findings of the study. ADHF, acute decompensated heart failure; IV, intravenous; IVC, inferior vena cava; NT-proBNP, N-terminal pro-B-type natriuretic peptide; OCT, optical coherence tomography; OCT-A, optical coherence tomography angiography. Abstract Aims To investigate the changes in retinal microvasculature by contemporary imaging techniques during episodes of acute decompensated heart failure (ADHF) and following recompensation compared to age-matched contr
MIBHS
DECEMBER 27, 2024
Heart bypass surgery, formally known as coronary artery bypass graft (CABG) surgery, is a life-saving procedure that helps improve blood flow to the heart when coronary arteries become blocked or narrowed. This surgery involves creating new pathways for blood to flow to the heart muscle by bypassing the blocked sections of the arteries. While this procedure can significantly enhance heart function and reduce symptoms of heart disease, it does come with potential risks and complications.
Physiologically Speaking
DECEMBER 2, 2024
Greetings! In case you missed it, here are all of the studies I covered in the November 2024 installments of the Physiology Friday newsletter. Enjoy (or re-enjoy) these summaries, and don’t forget to share them with someone you think might learn from or be interested in them. Thanks for reading! Physiologically Speaking is a reader-supported publication.
Heart BMJ
DECEMBER 23, 2024
Degenerative mitral valve disease is common. Up to a quarter of patients with degenerative mitral valve disease may be asymptomatic despite having severe valve regurgitation. Current guideline indications for intervention in asymptomatic patient are centred on left ventricular dimensions and ejection fraction and may include consideration in atrial fibrillation, pulmonary hypertension and those with left atrial dilatation.
AMS Cardiology
DECEMBER 16, 2024
The magic of the holidays often comes with hidden challenges for our hearts. Rich foods, packed calendars, and holiday pressures can derail even our best health intentions. Yet maintaining heart health doesn’t mean sacrificing the festivities. Simple, mindful choices during the holiday season can protect your cardiovascular health and lay the foundation for a lively year ahead.
Dr. Smith's ECG Blog
DECEMBER 6, 2024
A 50-something man presented with worsening severe exertional chest pain which was just resolving as he had an ECG recorded in triage. Time zero. Are the T-waves in leads I and II hyperacute? Hard to tell. How can we know? By the evolution of the ECG! Watch what happends as the heart recovers from its episode of ischemia. The T-waves deflate, demonstrating that the first one was indeed hyperacute. 2 hours T-waves in lead II are significant smaller In lead I not much difference Troponins returned
Frontiers in Cardiovascular Medicine
DECEMBER 3, 2024
BackgroundIn the era of fluoroless catheter ablation (CA), achieving a successful transseptal puncture (TSP) presents a significant challenge. We introduce a novel technique for zero-fluoroscopy and cost-effective needle-free TSP.Case summaryWe describe two cases where a GMS-1 guidewire (0.025 inch, pigtail configuration; Toray Medical Co., Ltd., Japan) was utilized for TSP.
CardiacWire
DECEMBER 4, 2024
The red hot weight loss segment just got even hotter, as the Phase 2 trial of Amgen’s maridebart cafraglutide (MariTide) yielded exceptional body mass reductions among people with obesity and T2D, propelling the pharma giant closer to FDA approval. Like Eli Lilly’s tirzepatide, MariTide is a GLP-1/GIP-agonist, setting it apart from Novo Nordisk’s popular GLP-1 semaglutide.
Med Page Today
DECEMBER 3, 2024
(MedPage Today) -- Traces of nine essential metals and non-essential metals in urine were linked with lower cognitive performance and the risk of future dementia, a large prospective study showed. The study assessed concentrations of the essential.
Heart BMJ
DECEMBER 23, 2024
Background Intravascular lithotripsy (IVL) is increasingly used for treatment of coronary artery calcification. This study aimed to evaluate contemporary utilisation patterns, safety and efficacy of IVL in an unselected real-world patient cohort. Methods We included 454 patients undergoing IVL from May 2019 to February 2024 across seven centres in two European countries.
Cardiometabolic Health Congress
DECEMBER 17, 2024
Cardiovascular and renal health are undeniably linkedwhen one system is compromised, the other is often at risk. For healthcare providers, adopting an integrated, patient-centered approach is important for better outcomes. Here are our five top tips to help you stay aligned with the latest guidelines and improve cardiorenal care. 1. Embrace a Multidisciplinary Perspective Cardiorenal health isnt just a focus area for cardiologists and nephrologistsit affects a wide range of specialties, includi
Dr. Smith's ECG Blog
DECEMBER 29, 2024
Dizziness is so unlikely to be OMI without an obvious ECG, that I am going to pretend that this patient presented with chest pain. The PMCardio Queen of Hearts app asks you, before giving an interpretation of OMI ("STEMI-Equivalent"), whether the patient's clinical presentation is high risk for OMI. If no, then she will tell you that the case is outside of the intended use group.
Frontiers in Cardiovascular Medicine
DECEMBER 23, 2024
BackgroundHeart failure (HF) is a leading cause of morbidity and mortality worldwide. Various factors can exacerbate disease progression in patients with HF and negatively impact treatment outcomes. This study aims to evaluate the pooled prevalence and contributing factors associated with poor heart failure treatment outcomes in Ethiopia.MethodsA systematic review and meta-analysis were conducted using five databases: Google Scholar, ScienceDirect, Hinari, PubMed, and Scopus.
Physiologically Speaking
DECEMBER 4, 2024
Greetings! Today, I’m cross-posting an article (with permission) from performance coach Jonah Rosner. I’ve been following Jonah on social media for a while and love his digestible and practical content on being a better runner and athlete. In this post, he outlines 4 strategies that you can use to prevent bone injuries from happening while training.
Science Daily - Heart Disease
DECEMBER 20, 2024
Physician-scientists found that a subset of artificial heart patients can regenerate heart muscle, which may open the door to new ways to treat and perhaps someday cure heart failure.
International Journal of Cardiovascular Sciences
DECEMBER 3, 2024
We would like to inform you that the deadline for submitting articles for the special collection on Artificial Intelligence in Cardiovascular Health has been extended to March 1, 2024. This special collection aims to explore advancements, applications, and challenges of artificial intelligence in the context of cardiovascular health, promoting the dissemination of knowledge and scientific innovations in the field.
Medical Xpress - Cardiology
DECEMBER 19, 2024
We sing about how Christmas brings "tidings of comfort and joy," but the holiday also brings something not so "merry and bright.
Dr. Paddy Barrett
DECEMBER 30, 2024
When medical interventions are being evaluated for cost-effectiveness, the benchmark for one additional quality year of life is $50,000. This is known as a QALY or Quality Adjusted Life Year. If the intervention costs less than $50,000 per year to provide an additional quality year, it is considered cost-effective. Of course, this is a somewhat arbitrary figure, but we have to start somewhere.
Frontiers in Cardiovascular Medicine
DECEMBER 18, 2024
Despite improvements in clinical outcomes of acute myocardial infarction (AMI), mortality rates remain high, indicating the need for further understanding of the pathogenesis and developing more effective cardiac protection strategies. Extracellular vesicles (EVs) carry proteins and noncoding RNAs (ncRNAs) derived from different cardiac cell populations, mainly including cardiomyocytes, endothelial cells, endothelial progenitor cells, cardiac progenitor cells, cardiosphere-derived cells, immune
Med Page Today
DECEMBER 31, 2024
(MedPage Today) -- A three-step process underscores new clinical practice guidelines for primary and specialty care clinicians to evaluate patients who may have cognitive impairment or dementia due to Alzheimer's or a related disease. In broad.
Science Daily - Heart Disease
DECEMBER 4, 2024
Earlier research showed that primary care clinicians using AI-ECG tools identified more unknown cases of a weak heart pump, also called low ejection fraction, than without AI. New study findings suggest that this type of screening is also cost-effective in the long term, especially in outpatient settings.
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