Med Page Today
JANUARY 23, 2025
(MedPage Today) -- For people with atrial fibrillation (Afib), investigational abelacimab proved to be a potent dual factor XI/XIa inhibitor with much lower safety risks compared with a direct oral anticoagulant (DOAC), according to the AZALEA.
Medical Xpress - Cardiology
JANUARY 23, 2025
Patients with atrial fibrillation are typically prescribed an anticoagulant, or blood thinner, to reduce the risk of stroke, but many may discontinue them or never receive a prescription due to concerns of increased risk of bleeding complications.
Med Page Today
JANUARY 23, 2025
(MedPage Today) -- More thyroid cancers were detected soon after starting a GLP-1 receptor agonist than other diabetes drugs, a secondary analysis of a target trial emulation of a comparative effectiveness study found. Of over 350,000 adults with.
HCPLive
JANUARY 23, 2025
A new study showed sedative, hypnotic, and anxiolytic use disorder diagnoses rose 3- to 5-fold from 20012019 among adolescents and young adults.
Medical Xpress - Cardiology
JANUARY 23, 2025
According to new research from the University of Missouri School of Medicine, the number of mechanical thrombectomies performed at hospitals is not an accurate indicator of patient outcomes.
HCPLive
JANUARY 23, 2025
CRN declined from 23.2% to 13.1% between 2011 and 2022 but still affects around 2.5 million adults in the US.
Medical Xpress - Cardiology
JANUARY 23, 2025
The prevalence of daily low-dose aspirin use fell significantly after the American College of Cardiology and the American Heart Association narrowed recommendations in 2019. However, new research published Jan. 22 in JAMA shows that message has not reached all population segments equally, leaving some groups at greater risk of adverse effects like gastrointestinal bleeding and intracerebral hemorrhage.
Cardiovascular Update brings together the best content for cardiovascular medicine professionals from the widest variety of industry thought leaders.
HeartRhythm
JANUARY 23, 2025
Catheter ablation is an effective treatment for atrial fibrillation (AF). Pulsed field ablation (PFA) has emerged as a novel energy modality, which relies on high-voltage electric fields to achieve cardiac tissue ablation. Data on its efficacy in the elderly are scarce.
HCPLive
JANUARY 23, 2025
The approval of Amneal Pharmaceuticals generic version of rifaximin 550 mg oral tablets is tentative due to the products involvement in litigation.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
ObjectiveTo quantify the risk of heart diseases (HD) and determine the relationship between physical activity (PA) dimensions and HD among Chinese middle-aged and older individuals.MethodsUsing data from the China Health and Retirement Longitudinal Study (CHARLS, 2018), 16,927 participants were included in this study. Multivariate logistic regression was performed to determine the association between HD risk and PA dimensions, including volume, intensity, frequency, and duration.
HCPLive
JANUARY 23, 2025
Findings point to global increases in alcohol use disorder, alcohol-associated liver disease, and liver cancer attributable to alcohol from 2000-2021.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
Background Early prediction of heart failure (HF) after acute myocardial infarction (AMI) is essential for personalized treatment. We aimed to use interpretable machine learning (ML) methods to develop a risk prediction model for HF in AMI patients.MethodsWe retrospectively included patients initially with AMI who received percutaneous coronary intervention (PCI) in our hospital from November 2016 to February 2020.
HCPLive
JANUARY 23, 2025
The lower BHI observed was likely associated with effects on the musculoskeletal system and not the central nervous system.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
Accurate evaluation of coronary artery pathology is essential for risk stratification and tailoring appropriate treatment. Intravascular imaging was introduced for this purpose 40 years ago enabling for the first time in vivo plaque characterization. Since then, several studies have evaluated the efficacy of the existing intravascular imaging modalities in assessing plaque pathology and composition and their potential in guiding intervention and predicting vulnerable plaques.
HCPLive
JANUARY 23, 2025
These data highlight the effectiveness of long-term ritlecitinib treatment among those with alopecia areata and significant scalp hair loss.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
The increased use of radiofrequency ablation (RFA) for atrial fibrillation (AF) has led to a rise in cases of pulmonary vein stenosis or occlusion (PVS/O) as a complication. While this occurrence was once rare, the growing number of patients undergoing this procedure has made it more prevalent. The actual frequency of pulmonary vein (PV) occlusion remains a topic of debate.
HCPLive
JANUARY 23, 2025
In this episode, hosts explore the latest updates to the ADA Standards of Care on therapeutic innovations and their real-world impact on diabetes management.
Journal of the American Heart Association
JANUARY 23, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundAcute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. We studied the association between the aggregated stressinduced changes in hemodynamic and vascular function tests with adverse cardiovascular outcomes in patients with coronary artery disease, after adjusting for sociodemographic and clinical factors.Methods and ResultsIndivi
HCPLive
JANUARY 23, 2025
These findings highlight the efficacy and tolerance of treatment with oral baricitinib along with phototherapy among those with the most severe form of vitiligo.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
IntroductionMyocardial perfusion MRI is important for diagnosing coronary artery disease, but current clinical methods face challenges in balancing spatial resolution, temporal resolution, and slice coverage. Achieving broader slice coverage and higher temporal resolution is essential for accurately detecting abnormalities across different slice locations but remains difficult due to constraints in acquisition speed and heart rate variability.
HCPLive
JANUARY 23, 2025
Abelacimab achieved notably lower levels of free factor XI and fewer bleeding events than standard-of-care rivaroxaban in the Phase 2b trial.
Frontiers in Cardiovascular Medicine
JANUARY 23, 2025
The primary electrophysiological mechanism of atrial fibrillation (AF) maintenance is poorly defined. AF mapping studies readily record focal activations (defining them as focal sources or breakthroughs) and incomplete reentries (defining them as reentries or would-be-reentries) but do not or rarely detect complete circular activations. Electrophysiological alterations induced by anti-AF drugs before AF cardioversion may help delineate the mechanism of AF maintenance.
HCPLive
JANUARY 23, 2025
A new study identified psychiatric, neurological, and somatic comorbidities of intermittent explosive disorder.
Cardiovascular Diabetology
JANUARY 23, 2025
Obesity, a major risk factor for cardiovascular disease (CVD), is associated with hypertension and vascular dysfunction. Perivascular adipose tissue (PVAT), a metabolically active tissue surrounding blood vess.
Medical Xpress - Cardiology
JANUARY 23, 2025
A recent study conducted by the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) found that mislabeled NSAID (Non-Steroidal Anti-Inflammatory Drug) allergies for stroke patients hinders the use of effective medications for them, leading to poorer treatment outcomes. It also revealed that when stroke survivors with NSAID allergy labels underwent testing, 80% were found to be mislabeled.
Cardiovascular Diabetology
JANUARY 23, 2025
The Cardiovascularkidneymetabolic (CKM) syndrome, a concept recently proposed by the American Heart Association (AHA), highlights the intricate connection between metabolic, renal, and cardiovascular illness.
HCPLive
JANUARY 23, 2025
MASLD and MetALD were linked to a greater risk of incident IBD, with risk increasing as the number of associated cardiometabolic risk factors increased.
Cardiovascular Diabetology
JANUARY 23, 2025
Diabetes mellitus (DM) and proteinuria each independently raise the risk of atrial fibrillation (AF). We aimed to investigate the relationship between proteinuria and the risk of incident AF across glycemic st.
Becker's Hospital Review - Cardiology
JANUARY 23, 2025
Florida and Illinois have the most top-ranked hospitals for stent placement in the U. S. , according to the WebMD Choice Awards.
HeartRhythm
JANUARY 23, 2025
We thank Hundal and colleagues for their letter1 regarding our analysis of the incidence of new-onset and progressive atrial fibrillation (AF) in mavacamtent-treated patients with obstructive hypertrophic cardiomyopathy (oHCM)2. Of note, the new-onset AF event rate (1/84; 1.4%) reported by Hundal et al1 stands in contrast to that observed in our study (7/63; 11%)2 and aligns with the AF adverse event rate observed in pivotal clinical trials (2%-3.6%)3.
Becker's Hospital Review - Cardiology
JANUARY 23, 2025
The drivers behind burnout in cardiovascular nursing require country- and systemwide interventions unique to the speciality, according to a statement published Dec. 18 in the Journal of the American Heart Association.
HeartRhythm
JANUARY 23, 2025
The authors of the current guidelines on the management of patients with atrial fibrillation (AF) state the following in the chapter on interventional left atrial appendage occlusion (LAAO): Patients with a contraindication to all of the oral anticoagulation (OAC) options () have the most appropriate rationale for LAAO implantationdespite the paradox that the need for post-procedure antithrombotic treatment exposes the patient to a bleeding risk that may be equivalent to that of direct (D)OACs.
Journal of the American Heart Association
JANUARY 23, 2025
Journal of the American Heart Association, Ahead of Print.
HeartRhythm
JANUARY 23, 2025
Pulsed-field ablation (PFA) offers notable advantages in atrial fibrillation (AF) ablation by selectively targeting cardiomyocytes via an irreversible electroporation mechanism, thereby minimizing damage to surrounding tissues. Although clinical studies demonstrate that PFA is both safe and effective, PFA-mediated hemolysis and potential acute kidney injury (AKI) development have been recently reported.
Journal of the American Heart Association
JANUARY 23, 2025
Journal of the American Heart Association, Ahead of Print.
HeartRhythm
JANUARY 23, 2025
The prevalence of atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM) is reported to be higher than in the general population, ranging from 3.6% to 8.9 % [1]. Also, the coexistence of T2DM and AF increases the risk of adverse cardiovascular events, including heart failure, atherosclerotic cardiovascular disease and mortality [2].
Journal of the American Heart Association
JANUARY 23, 2025
Journal of the American Heart Association, Ahead of Print. BackgroundApolipoprotein C3 (apo C3) is primarily secreted by the liver and is involved in promoting sterile inflammation and organ damage under pathological conditions. Previous studies have shown that apo C3 is abundant in the plasma exosomes of patients with aortic dissection (AD), but its specific role in AD remains unclear.Methods and ResultsIn vivo, adenoassociated virus was used to knock down hepatic apo C3 expression in an AD mou
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